Abstract: Provided is a light beam emission device and a light beam projection device, that are downsizable, have a simple configuration, and simplify complicated processing of video signals, such as the timing adjustment of video output signals, without generating color irregularity. The devices include: a plurality of light sources; and a condensing member. A range in the light source array direction, in which emission spots of the light beams emitted from the plurality of light sources respectively exist, is within a size in the array direction of a light beam, immediately after the light beam emitted from an emission spot located most closely to the center of the plurality of light sources, with respect to the condensing member, passed through the condensing member.

Abstract: An optical multiplexer and an optical multiplexing method capable of multiplexing light of four or more types of wavelengths are provided. An optical multiplexer 1 capable of multiplexing light of a plurality of wavelengths includes a plurality of coupling parts 10 each including a pair of main entrance paths 110, 120, a pair of main exit paths 130, 140, and a main coupler 150 arranged between the main entrance paths 110, 120 and the main exit paths 130, 140, the main coupler 150 causing light entering from the main entrance paths 110, 120 to be coupled and exit from the main exit paths 130, 140, in which one of the main entrance paths 110, 120 of the coupling parts 10 is joined to one of the main exit paths 130, 140 of anther coupling parts 10, and the main coupler 150 each has coupling characteristics different from those of at least one other main coupler 150.

Abstract: An optical multiplexer including a first and a second optical waveguides, and a multiplexing unit. The first and second optical waveguides have a first and a second mode coupling regions being proximate to each other with a predetermined gap width, the optical waveguides in the first and second mode coupling regions form the multiplexing unit. Light transfers between the optical waveguides in the first and second mode coupling regions, first light in the optical waveguide in the first mode coupling region and second light in the optical waveguide in the first or second mode coupling regions having the wavelength different from the first light are multiplexed to one of the waveguides in the first and second mode coupling regions, and the core cross-section of the optical waveguide at least in the first and second mode coupling regions in the first and second optical waveguides is asymmetric in the height direction.

Abstract: An object of the present invention is to provide a compound useful as a therapeutic drug for an autoimmune disease such as systemic lupus erythematosus (SLE) and lupus nephritis of SLE patients by suppressing immune cell function by inhibiting proliferation of activated T cells and production of interferon alpha (IFN-?). The present invention provides a compound represented by formula (I): wherein R1, R2 and R3 are the same as defined in the specification, or a pharmaceutically acceptable salt thereof.

Abstract: An optical multiplexer reduced in background light and reduced in size is provided. The optical multiplexer takes a plurality of light beams having different wavelengths as input from respective waveguides, and outputs multiple light obtained by multiplexing the plurality of light beams by a directional coupler. Background light is reduced by a reflection groove which reflects excess light outputted from a discard port of the directional coupler, and downsizing of the optical multiplexer is achieved.

Abstract: Disclosed herein are liquid pharmaceutical formulations comprising levodopa amino acid conjugates that may further comprise a decarboxylase inhibitor, such as carbidopa, an antioxidant, a solvent, or any other pharmaceutically acceptable excipient. Further disclosed are methods of treating generative conditions and/or conditions characterized by reduced levels of dopamine in the brain, such as Parkinson's disease, comprising administering the disclosed liquid pharmaceutical formulations. Disclosed also are LDAA conjugate compounds.

Abstract: A retinal scanning display device including an optical system emits laser light to a pupil of a user, an optical multiplexer individually receives types of laser light having different wavelengths emitted from a plurality of semiconductor lasers, which combines the types of laser light coaxially to output the combined laser light. On the optical multiplexer, a beam shaper shapes the combined laser light into a light beam having a predetermined divergence or convergence angle, and a direction-of-emission changer changes image signal corresponding to an image to be formed, the direction of emission of the light beam output through the beam shaper within at least a plane intersecting the direction of emission. Then, an optical engine formed with the semiconductor lasers, the optical multiplexer, the beam shaper and the direction-of-emission changer guides the laser light emitted from the direction-of-emission changer to the position of the pupil of the user.

Abstract: To provide a multiplexer that makes it possible to achieve a reduction in size and that minimizes the influence of the expansion of laser light on a multiplexing unit. A multiplexer is provided with a plurality of waveguides, multiplexing units that are provided at an intermediate location within the waveguides, and laser light sources, wherein: the first multiplexing unit is arranged at a position that is closest to the laser light sources; and the laser light sources that have an optical axis at a position that is separated from the transmission axis of the visible light that is introduced into the first multiplexing unit are arranged so that the optical axis is inclined with respect to the transmission axis and the outer periphery of laser light that expands at a predetermined expansion angle passes in front of the first multiplexing unit.

Abstract: Provided is a light beam emission device and a light beam projection device, that are downsizable, have a simple configuration, and simplify complicated processing of video signals, such as the timing adjustment of video output signals, without generating color irregularity. The devices include: a plurality of light sources; and a condensing member. A range in the light source array direction, in which emission spots of the light beams emitted from the plurality of light sources respectively exist, is within a size in the array direction of a light beam, immediately after the light beam emitted from an emission spot located most closely to the center of the plurality of light sources, with respect to the condensing member, passed through the condensing member.

Abstract: The present invention relates to an optical scanning type video projection device that decreases the height of the optical scanning type video projection device by improving the disposition of a light source module device and an optical scanning mirror device. The optical scanning type video projection device has: a first substrate on which an optical waveguide type multiplexer having a plurality of optical waveguides and a light multiplexer is provided; a second substrate on which an optical scanning mirror device having a movable mirror is provided; and an optical member configured to guide a light beam emitted from the optical waveguide type multiplexer to the movable mirror in a direction that is different from an emitting direction of the light beam. The first substrate and the second substrate are disposed in parallel with each other.

Abstract: To provide a multiplexer that makes it possible to achieve a reduction in size and that minimizes the influence of the expansion of laser light on a multiplexing unit. A multiplexer is provided with a plurality of waveguides, multiplexing units that are provided at an intermediate location within the waveguides, and laser light sources, wherein: the first multiplexing unit is arranged at a position that is closest to the laser light sources; and the laser light sources that have an optical axis at a position that is separated from the transmission axis of the visible light that is introduced into the first multiplexing unit are arranged so that the optical axis is inclined with respect to the transmission axis and the outer periphery of laser light that expands at a predetermined expansion angle passes in front of the first multiplexing unit.

Abstract: The present invention provides a compound having a particular chemical structure or a pharmacologically acceptable salt thereof which has an excellent inhibitory effect on EZH1 and/or EZH2 activity. The present invention provides a compound having a 1, 3-benzodioxole structure represented by the general formula (I) or a pharmacologically acceptable salt thereof, or a pharmaceutical composition comprising the compound (wherein R1, R2, R3, R4, R5, R6, and V in the formula (I) are each as defined in the present specification).

Abstract: To provide a multiplexer that makes it possible to achieve a reduction in size and that minimizes the influence of the expansion of laser light on a multiplexing unit. A multiplexer is provided with a plurality of waveguides, multiplexing units that are provided at an intermediate location within the waveguides, and laser light sources, wherein: the first multiplexing unit is arranged at a position that is closest to the laser light sources; and the laser light sources that have an optical axis at a position that is separated from the transmission axis of the visible light that is introduced into the first multiplexing unit are arranged so that the optical axis is inclined with respect to the transmission axis and the outer periphery of laser light that expands at a predetermined expansion angle passes in front of the first multiplexing unit.

Abstract: To provide a multiplexer that makes it possible to achieve a reduction in size and that minimizes the influence of the expansion of laser light on a multiplexing unit. A multiplexer is provided with a plurality of waveguides, multiplexing units that are provided at an intermediate location within the waveguides, and laser light sources, wherein: the first multiplexing unit is arranged at a position that is closest to the laser light sources; and the laser light sources that have an optical axis at a position that is separated from the transmission axis of the visible light that is introduced into the first multiplexing unit are arranged so that the optical axis is inclined with respect to the transmission axis and the outer periphery of laser light that expands at a predetermined expansion angle passes in front of the first multiplexing unit.

Abstract: To provide a multiplexer that makes it possible to achieve a reduction in size and that minimizes the influence of the expansion of laser light on a multiplexing unit. A multiplexer is provided with a plurality of waveguides, multiplexing units that are provided at an intermediate location within the waveguides, and laser light sources, wherein: the first multiplexing unit is arranged at a position that is closest to the laser light sources; and the laser light sources that have an optical axis at a position that is separated from the transmission axis of the visible light that is introduced into the first multiplexing unit are arranged so that the optical axis is inclined with respect to the transmission axis and the outer periphery of laser light that expands at a predetermined expansion angle passes in front of the first multiplexing unit.

Abstract: To provide a multiplexer that makes it possible to achieve a reduction in size and that minimizes the influence of the expansion of laser light on a multiplexing unit. A multiplexer is provided with a plurality of waveguides, multiplexing units that are provided at an intermediate location within the waveguides, and laser light sources, wherein: the first multiplexing unit is arranged at a position that is closest to the laser light sources; and the laser light sources that have an optical axis at a position that is separated from the transmission axis of the visible light that is introduced into the first multiplexing unit are arranged so that the optical axis is inclined with respect to the transmission axis and the outer periphery of laser light that expands at a predetermined expansion angle passes in front of the first multiplexing unit.

Abstract: To provide a multiplexer that makes it possible to achieve a reduction in size and that minimizes the influence of the expansion of laser light on a multiplexing unit. A multiplexer is provided with a plurality of waveguides, multiplexing units that are provided at an intermediate location within the waveguides, and laser light sources, wherein: the first multiplexing unit is arranged at a position that is closest to the laser light sources; and the laser light sources that have an optical axis at a position that is separated from the transmission axis of the visible light that is introduced into the first multiplexing unit are arranged so that the optical axis is inclined with respect to the transmission axis and the outer periphery of laser light that expands at a predetermined expansion angle passes in front of the first multiplexing unit.

Abstract: The present invention provides a compound having a particular chemical structure or a pharmacologically acceptable salt thereof which has an excellent inhibitory effect on EZH1 and/or EZH2 activity. The present invention provides a compound having a 1,3-benzodioxole structure represented by the general formula (I) or a pharmacologically acceptable salt thereof, or a pharmaceutical composition comprising the compound (wherein R1, R2, R3, R4, R5, R6, and V in the formula (I) are each as defined in the present specification).

Abstract: The present invention provides a compound having a particular chemical structure or a pharmacologically acceptable salt thereof which has an excellent inhibitory effect on EZH1 and/or EZH2 activity. The present invention provides a compound having a 1,3-benzodioxole structure represented by the general formula (I) or a pharmacologically acceptable salt thereof, or a pharmaceutical composition comprising the compound (wherein R1, R2, R3, R4, R5, R6, and V in the formula (I) are each as defined in the present specification).

Abstract: To provide a multiplexer that makes it possible to achieve a reduction in size and that minimizes the influence of the expansion of laser light on a multiplexing unit. A multiplexer is provided with a plurality of waveguides, multiplexing units that are provided at an intermediate location within the waveguides, and laser light sources, wherein: the first multiplexing unit is arranged at a position that is closest to the laser light sources; and the laser light sources that have an optical axis at a position that is separated from the transmission axis of the visible light that is introduced into the first multiplexing unit are arranged so that the optical axis is inclined with respect to the transmission axis and the outer periphery of laser light that expands at a predetermined expansion angle passes in front of the first multiplexing unit.