Patents by Inventor Akira Nakao

Akira Nakao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of stimulating superoxide generation
    Patent number: 5082854
    Abstract: The present invention is directed to a method of stimulating superoxide generation using phenolic thioethers which stimulate the generation of superoxide.
    Type: Grant
    Filed: September 7, 1990
    Date of Patent: January 21, 1992
    Assignee: G. D. Searle & Co.
    Inventors: Richard A. Mueller, Akira Nakao, Richard A. Partis
  • Method of inhibiting superoxide generation
    Patent number: 5064860
    Abstract: The present invention relates to a method of inhibiting superoxide generation which comprises administering to a mammal in need of such treatment an amount of a compound of the Formula I ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and independently represent tert-alkyl or phenyl; Alk.sup.1 represents straight or branched chain alkylene of 1 to 10 carbon atoms, X represents sulfur or oxygen, Alk.sup.2 represents straight or branched chain alkylene of 1 to 4 carbon atoms; and m is 0, 1 or 2; or a pharmaceutically acceptable salt or stereoisomer or geometric isomer thereof, which is effective to inhibit superoxide generation.
    Type: Grant
    Filed: September 7, 1990
    Date of Patent: November 12, 1991
    Assignee: G. D. Searle & Co.
    Inventors: Richard A. Mueller, Akira Nakao, Richard A. Partis