Patents by Inventor Alan AN

Alan AN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Soluble guanylate cyclase activators
    Patent number: 9611278
    Abstract: A compound of Formula I or a pharmaceutically acceptable salt thereof, are capable of modulating the body's production of cyclic guanosine monophosphate (“cGMP”) and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The invention furthermore relates to processes for preparing compounds of Formula I, or a pharmaceutically acceptable salt thereof, for their use in the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical preparations which comprise compounds of Formula I or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: December 5, 2014
    Date of Patent: April 4, 2017
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Xiaoqing Han, Alan Whitehead, Subharekha Raghavan, Jonathan Groeper, Jian Guo, Yong Zhang
  • Ultrasonic airspeed and direction sensor system
    Patent number: 9612252
    Abstract: An ultrasonic airspeed and direction sensor system comprising an ultrasonic sensor array including an elongate base member for mounting to a vehicle, such as a helicopter, so as to extend outwardly from the vehicle. A number of radially extending support members are connected to the base member. The support members carry ultrasonic transducers arranged to define at least four bidirectional ultrasonic paths between respective pairs of the transducers, the ultrasonic paths being arranged into at least three non-coplanar sets. A processing system monitors the passage of ultrasonic signals along the paths to generate corresponding time of flight data, making a weighted selection containing at least one path from each of at least three sets, and processing the time of flight data for the selected paths, proportionate to the determined weighting, to generate airspeed and direction information.
    Type: Grant
    Filed: November 5, 2014
    Date of Patent: April 4, 2017
    Assignee: Meggitt (UK) Limited
    Inventor: Alan Waddington
  • Biomimetic chemical sensors using nanoelectronic readout of olfactory receptors
    Patent number: 9612240
    Abstract: The present invention provides biomimetic sensor devices that utilize proteins—such as G-protein coupled receptors—and are useful in high-sensitivity analysis of analyte-containing samples. These sensors may be used to determine the presence or concentration of one or more analytes in a sample. The invention also includes methods of fabricating the devices and methods of using the devices to assay samples.
    Type: Grant
    Filed: June 29, 2011
    Date of Patent: April 4, 2017
    Assignee: The Trustees Of The University Of Pennsylvania
    Inventors: Alan T. Johnson, Jr., Brett R. Goldsmith, Joseph J. Mitala, Jr., Bohdana Discher, Stephen G. Sligar, Timothy H. Bayburt
  • Power control of optical signals having different polarizations
    Patent number: 9614639
    Abstract: Consistent with an aspect of the present disclosure, an optical communication apparatus is provided that transmits a WDM signal including a plurality of optical channels, wherein each channel has a corresponding one of a plurality of wavelengths. Each of the plurality of optical channels includes optical signals having first (e.g., TE) and second (e.g., TM) polarizations. In one example, each polarized optical signal is modulated in accordance with an identifying tone. The optical channels are combined onto a waveguide, and an optical tap connected or coupled to the waveguide supplies a portion of the WDM signal including a composite of the optical channels to a photodiode. The aggregate power received by the photodiode includes the power associated with each optical channel, and the power of each channel is the sum of the powers of individual polarized optical signals within that channel.
    Type: Grant
    Filed: September 25, 2009
    Date of Patent: April 4, 2017
    Assignee: Infinera Corporation
    Inventor: Alan C. Nilsson
  • Systems and methods for automatically inspecting wire segments
    Patent number: 9612210
    Abstract: A wire inspection system is provided. The wire inspection system includes a mirror assembly including an odd number of sides arranged to form a pyramid structure configured to surround a wire segment, wherein a plurality of the sides include a mirror, a light source configured to illuminate the wire segment, and at least one camera configured to acquire a plurality of images of the wire segment that are reflected by the plurality of mirrors, wherein each image of the plurality of images shows a different side of the wire segment.
    Type: Grant
    Filed: June 25, 2015
    Date of Patent: April 4, 2017
    Assignee: The Boeing Company
    Inventors: Gary Alan Ray, Bentley Edwin Northon, Bradley J. Mitchell, James Ridgeway Gillis
  • Macrocyclic insulin-degrading enzyme (IDE) inhibitors and uses thereof
    Patent number: 9610322
    Abstract: Macrocyclic compounds that specifically inhibit insulin degrading enzyme (IDE) are provided. Pharmaceutically acceptable salts, solvates, hydrates, stereoisomers, polymorphs, tautomers, isotopically enriched forms, and prodrugs of the macrocyclic IDE inhibitors are also described. Pharmaceutical compositions are also provided. In vivo and in vitro methods of using the IDE inhibitor, and pharmaceutical compositions comprising the IDE inhibitor, for example, for the inhibition of IDE in a subject exhibiting aberrant IDE activity, impaired insulin signaling, or insulin resistance, for example, a subject having diabetes, are also provided.
    Type: Grant
    Filed: January 22, 2016
    Date of Patent: April 4, 2017
    Assignee: President and Fellows of Harvard College
    Inventors: David R. Liu, Juan Pablo Maianti, Alan Saghatelian, Ralph E. Kleiner
  • Histone demethylase inhibitors
    Patent number: 9611221
    Abstract: The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted amidopyridine or amidopyridazine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: April 4, 2017
    Assignee: Celgene Quanticel Research, Inc.
    Inventors: Young K. Chen, Toufike Kanouni, Zhe Nie, Jeffrey Alan Stafford, James Marvin Veal, Michael Brennan Wallace
  • Horizontal directional drilling system including sonde position detection using global positioning systems
    Patent number: 9611732
    Abstract: A locator device and methods of use are disclosed. The locator device includes a first locating system configured to generate to sense an electromagnetic field emanating from a sonde associated with a drill head, and a second locating system including a global positioning system. The locator device includes a display on the locating system configured to display a map of the area in which the locator device resides based on a location detected by the global positioning system. The locator device also includes control electronics configured to, upon receipt of an input from a user, record location data in a memory associated with the locator device for use by a horizontal directional drilling control system.
    Type: Grant
    Filed: June 21, 2012
    Date of Patent: April 4, 2017
    Assignee: Vermeer Manufacturing Company
    Inventors: Scott Alan Rempe, Tony Briggs, David Hanson, Keith Sjostrom, Nathan Copeland, Hans Kelpe, Tod Michael, Chad Van Soelen
  • Gas water heater control alternate power source
    Patent number: 9612037
    Abstract: Systems, circuits, and methods for providing operating power to a gas control circuit board are disclosed. A first power source for a gas control circuit board is derived from a utility supplied AC source while a backup supply is provided based on current flowing through an anode rod associated with the water heater as defined by Faraday's Law of Electrolysis. The backup supply based on anode current flow provided operating power for the gas control circuit in case of loss of power from the utility supplied AC source.
    Type: Grant
    Filed: October 1, 2014
    Date of Patent: April 4, 2017
    Assignee: Haier US Appliance Solutions, Inc.
    Inventor: Brett Alan Farris
  • SECURITY RISK MANAGEMENT
    Publication number: 20170093901
    Abstract: Among other things, traces are received of activities of an online user who is associated with an entity. By analysis of the traces a security state of the entity is inferred. Also, a map is generated between (a) technical assets that contribute to security characteristics of respective entities and (b) the identities of the entities that are associated with the respective technical assets. At least part of the generating of the map is done automatically. A user can be engaged to assist in the generating of the map by presenting to the user through a user interface (a) data about the technical assets of entities and (b) an interactive tool for associating the technical assets with the identities of the entities.
    Type: Application
    Filed: August 17, 2016
    Publication date: March 30, 2017
    Inventors: Philip J. Gladstone, Alan J. Kirby, John M. Truelove, David Feinzeig, Nagarjuna Venna, Stephen Boyer
  • METHOD AND APPARATUS FOR REPRESENTING MULTIDIMENSIONAL DATA
    Publication number: 20170091302
    Abstract: The present invention relates to methods for representing multidimensional data. The methods of the present invention are well suited but not limited to the representation of multidimensional data in such a way as to enable the comparison and differentiation of data sets. For example, the invention may be applied to the representation of flow cytometric data. The invention further relates to a program storage device having instructions for controlling a computer system to perform the methods, and to a program storage device containing data structures used in the practice of the methods.
    Type: Application
    Filed: December 7, 2016
    Publication date: March 30, 2017
    Inventors: Allan Robert MOSER, Wade Thomas ROGERS, Herbert Alan HOLYST
  • FLEXIBLE FLAT EMITTER FOR X-RAY TUBES
    Publication number: 20170092456
    Abstract: A flat emitter configured for use in an X-ray tube is presented. The X-ray tube includes a first conductive section including a first terminal. Further, the X-ray tube includes a second conductive section including a second terminal. Also, the X-ray tube includes a third conductive section disposed between the first conductive section and the second conductive section, wherein the third conductive section is configured to emit electrons toward a determined focal spot, and wherein the third conductive section includes a plurality of slits subdividing the third conductive section into a winding track coupled to the first conductive section and the second conductive section, wherein at least two of the plurality of slits are interwound spirally to compose the winding track, and wherein the winding track is configured to expand and contract based on heat provided to the third conductive section.
    Type: Application
    Filed: September 28, 2015
    Publication date: March 30, 2017
    Inventors: Xi Zhang, Mark Alan Frontera, Sergio Lemaitre, John Scott Price, Uwe Wiedmann
  • MERGING PRINT DATA AND METADATA FOR A PRINT JOB PROCESSED IN A PRINT WORKFLOW
    Publication number: 20170090838
    Abstract: Systems and methods are provided for merging print data and metadata for a print job processed in a print workflow. One system is a print server that monitors an input device that receives print files and metadata files, groups at least one print file and at least one metadata file into a batch based on a predetermined pattern defined for the input device, and initiates processing of the batch as a print job in a print workflow in response to a determination that the batch meets a threshold condition. A step of the print workflow is configured to merge document properties from the at least one print file and the at least one metadata file into a single document properties file. Subsequent steps in the print workflow process the print job according to the single document properties file.
    Type: Application
    Filed: March 2, 2016
    Publication date: March 30, 2017
    Applicant: Ricoh Company, Ltd.
    Inventors: Thomas Nathan Bilan, Scott Matthew Jones, Linda Sue Liebelt, Michael Glen Lotz, Jeffrey Alan Sikkink, Marquis G. Waller
  • HYDROGENATION OF OXYGENATED MOLECULES FROM BIOMASS REFINING
    Publication number: 20170088498
    Abstract: The present disclosure relates to methods, processes, and systems for utilizing the dehydrogenation of 2-butanol for hydrogen consuming reactions of biomass or biomass-derived molecules. The present invention relates to methods, processes, and systems for utilizing the dehydrogenation of 2-butanol for hydrogen consuming hydrogenation, hydrogenolysis, or hydrodeoxygenation reactions of biomass or biomass-derived molecules.
    Type: Application
    Filed: May 12, 2015
    Publication date: March 30, 2017
    Applicant: VIRDIA, INC.
    Inventors: Robert JANSEN, Noa LAPIDOT, James Alan LAWSON, Michael Zviely, Neta MATIS, Lee MADSEN, Bassem HALLAC
  • Electrical Devices with Camera Sensors
    Publication number: 20170094134
    Abstract: An electrical device located in a space. The electrical device can include a functional component for delivering an output. The electrical device can also include a camera sensor that captures at least one sensory element, where the at least one sensory element indicates at least one condition within the space. The electrical device can further include a controller coupled to the functional component and the camera sensor, where the controller controls the functional component based on the at least one sensory element captured by the camera sensor.
    Type: Application
    Filed: September 30, 2016
    Publication date: March 30, 2017
    Applicant: COOPER TECHNOLOGIES COMPANY
    Inventors: Michael Alan Lunn, Brian Eugene Elwell
  • DIGITAL SECURITY SURVEILLANCE SYSTEM
    Publication number: 20170094218
    Abstract: A digital security surveillance system allows a user to store selected security surveillance feeds while the user is simultaneously watching or reviewing another feed. User control commands are accepted and sent through the system. The system parses the resulting digital stream and generates identifying information associated with at least one video segment of the digital stream. The video segments are stored on a storage device. When a security surveillance feed is requested for display, a corresponding stored digital stream is found and its video segments are extracted from the storage device and sent to a decoder that converts the digital stream into display output signals. The security surveillance feeds can be simultaneously sent to an external storage device such as a DVD recorder or VCR.
    Type: Application
    Filed: December 13, 2016
    Publication date: March 30, 2017
    Inventors: James M. Barton, Roderick James McInnis, Alan S. Moskowitz, Andrew Martin Goodman, Ching Tong Chow, Jean Swey Kao
  • Drone Safety Mechanism
    Publication number: 20170090474
    Abstract: A drone safety mechanism that prevents autonomously controlled or human-in-the-loop drones from interfering with aircraft. A signal is generated at the center of an area to be maintained free of drone activity. The signal decays with distance from the source of the signal. A sensor onboard the drone is able to measure the signal itself, as well as the strength of the signal. When the signal strength passes above some threshold level, or the signal provides some other message, an intention is sent to the drone that forces the drone to stop and/or descend. The signal may be a preexisting signal, such as an electromagnetic signal emitted from a radar system atop an air traffic control tower. To prevent drones interfering with aircraft in flight, the signal may be emitted from the aircraft itself.
    Type: Application
    Filed: September 28, 2016
    Publication date: March 30, 2017
    Inventors: Vincent Paul Spinella-Mamo, Alan Keith Hopkins
  • CASTING CORE APPARATUS AND CASTING METHOD
    Publication number: 20170087631
    Abstract: A casting mold apparatus includes a unitary ceramic core including: an outer skin defining an outer surface; and an internal support structure disposed inside the outer skin, the internal support structure defining a plurality of voids configured to admit fluid to the core.
    Type: Application
    Filed: September 30, 2015
    Publication date: March 30, 2017
    Inventor: Scott Alan Gold
  • Toothbrush
    Patent number: D782825
    Type: Grant
    Filed: June 3, 2015
    Date of Patent: April 4, 2017
    Assignee: COLGATE-PALMOLIVE COMPANY
    Inventors: Douglas J. Hohlbein, Al Sprosta, Alan Sorrentino
  • Gardening tool
    Patent number: D782887
    Type: Grant
    Filed: December 3, 2014
    Date of Patent: April 4, 2017
    Inventors: Amy Catherine Karp, Steven Alan East