Abstract: The present invention, a tire mounting device, is a lifting and transporting device for the facilitating the removing and replacing of a tire. The tire mounting device comprises a cross assembly, handle assembly, left fork assembly, and right fork assembly. The handle assembly is perpendicularly rigidly attached to the cross assembly. The left fork assembly and right fork assembly are rigidly attached to opposing ends of cross assembly which extends horizontally. An obtuse angle is disposed in an intermediate position with each fork assembly. Tire supports the underside of each fork assembly to allow for the transporting the tire upon the tire mounting device.

Abstract: Methods and intermediates for the synthesis of selective inhibitors of dipeptidyl peptidase IV (DPP-IV) are provided. Coupling of a carboxylate salt with a boro-proline derivative provides a protected form of a DPP-IV inhibitor, which may be deblocked to yield the medicinal compound. The carboxylate salt can be a crystalline form of a sodium salt or a dicyclohexylammonium salt. The inhibitor can be used in the treatment of diabetes.

Abstract: A tracking system counts events in the operation of multiple vending machines. The tracking system receives event data through multiple channels and stores the data for collection and analysis.

Abstract: The present invention provides novel compounds which mimic peptides with a C-terminal penultimate proline, such compounds being useful as protease inhibitors, particularly as inhibitors of serine proteases, and more particularly as inhibitors of the NS3 serine protease from hepatitis C. The compounds find utility as antiviral agents directed at hepatitis C. The invention further provides methods of employing such inhibitors, alone or in combination with other therapeutic agents, to treat hepatitis C infection in a subject in need of such treatment.

Abstract: The invention provides compounds that inhibit a viral protease enzyme of the hepatitis C virus (HCV). The compounds are adapted for treatment of a HCV infection in a patient with the disease. The compounds include analogs of tripeptides and tetrapeptides that resemble the viral protease substrate. The invention also provides pharmaceutical compositions and combinations, methods of preparation of the compounds, and methods of treatment of patients afflicted with HCV using the compounds.

Abstract: The present invention is directed to pyrrolidinylaminoacetyl pyrrolidine boronic acid compounds that display selective, potent dipeptidyl peptidase IV (DPP-IV) inhibitory activity. These compounds are useful for the treatment of disorders that can be regulated or normalized via inhibition of DPP-IV including those characterized by impaired glycemic control such as Diabetes Mellitus and related conditions. The compounds can be administered alone or with another medicament that displays pharmacological activity for treatment of these and other diseases.

Abstract: The present invention, a tire mounting device, is a lifting and transporting device for the facilitating the removing and replacing of a tire. The tire mounting device comprises a cross assembly, handle assembly, left fork assembly, and right fork assembly. The handle assembly is perpendicularly rigidly attached to the cross assembly. The left fork assembly and right fork assembly are rigidly attached to opposing ends of cross assembly which extends horizontally. An obtuse angle is disposed in an intermediate position with each fork assembly. Tire supports the underside of each fork assembly to allow for the transporting the tire upon the tire mounting device.

Abstract: The present application relates to perfume systems and consumer products comprising new perfumes and/or such perfume systems, as well as processes for making and using such perfume systems and consumer products.

Abstract: In the context of synthesizing heterocyclic boronic acid compounds, a convergent synthetic methodology is particularly efficient for preparing boropyrrolidines and derivatives of boropyrrolidines.

Abstract: The present invention provides tagged acyl phosphate probes (“TAPPs”), and methods of their preparation and use. The subject methods and compositions can provide enhanced simplicity and accuracy in identifying changes in the presence, amount, or activity of target proteins in a complex protein mixture, preferably nucleotide binding proteins using nucleotide binding protein-directed TAPPs. The profiling methods described herein can have a number of steps leading to the identification of target nucleotide binding protein(s) in a complex protein mixture.

Abstract: An optical film for use in transparent displays, such as reflective LCDs. The optical film has three-dimensional, prismatic structures that reflect incoming light. The prismatic structures are configured so that the reflecting facets orient the reflected light in desired reflective light pattern. The pattern shape and intensity can be controlled by the shape and dimensions of the various reflecting facets. In one embodiment, the height of the prismatic structure varies along two dimensions of the structure.

Abstract: A cutting tool assembly having a tool post capable of lateral movement along a work piece to be cut and an actuator with a tool tip. The actuator provides for variable control of the movement of the tool tip in an x-direction into the work piece at two simultaneously independent speeds for use in making microstructures in the work piece.

Abstract: A cutting tool assembly having a tool post capable of lateral movement along a work piece to be cut and an actuator with a tool tip. The actuator provides for variable control of the movement of the tool tip in a z-direction laterally along the work piece, while maintaining the tool tip at a substantially constant position in an x-direction into the work piece, for use in making microstructures in the work piece.

Abstract: A cutting tool assembly having a tool post capable of lateral movement along a work piece to be cut and an actuator with a tool tip. The actuator provides for independent and variable control of the movement of the tool tip in an x-direction into the work piece and in a z-direction laterally along the work piece for use in making microstructures in the work piece.

Abstract: A cutting tool assembly having a tool post capable of lateral movement along a work piece to be cut and an actuator with a tool tip. The actuator provides for variable control of a rotation of the tool tip about an axis parallel to a y-direction transversely across the work piece for use in making microstructures in the work piece.

Abstract: The present invention is directed to pyrrolidinylaminoacetyl pyrrolidine boronic acid compounds that display selective, potent dipeptidyl peptidase IV inhibitory activity. These compounds are useful for the treatment of disorders that can be regulated or normalized via inhibition of DPP-IV including those characterized by impaired glycemic control such as Diabetes Mellitus and related conditions. The compounds can be administered alone or with another medicament that displays pharmacological activity for treatment of these and other diseases.

Abstract: A cutting tool assembly having a tool post capable of lateral movement along a work piece to be cut and an actuator with at least one machined tool tip and possibly other tool tips. The actuator provides for control of the movement of the tool tip in an x-direction into and out of the work piece in order to make continuous or discontinuous microstructures in it. The machined tool tip provides for microstructures within microstructures. The machined work piece can be used to make microstructured articles such as films having non-adjacent lenslets.

Abstract: An imaging system comprises a laser source for emitting a beam, a photoconductive surface, a scanning device and a controller. The controller designates at least a first part and a second part of each line of image data, corresponding to a first part and a second part of each associated sweep of the beam. The laser source is modulated based upon the first part of the line of image data during the first part of a first one of the associated sweeps of the beam. The laser source is not modulated according to image data for the second part of the first one of the sweeps. During the first part of a second one of the associated sweeps of the beam, the laser source is not modulated based upon image data. However, the laser source is modulated based upon the second part of the line of image data during the second part of the second one of the sweeps.

Abstract: A cutting tool assembly having a tool post capable of lateral movement along a work piece to be cut and an actuator with a tool tip. The actuator provides for control of the movement of the tool tip in an x-direction into and out of the work piece in order to make discontinuous microstructures in it. The machined work piece can be used to make microstructured articles such as films having non-adjacent lenslets.

Abstract: A cutting tool assembly having a tool post capable of lateral movement along a work piece to be cut and an actuator with a tool tip. The actuator provides for independent and variable control of the movement of the tool tip in an x-direction into the work piece and in a z-direction laterally along the work piece for use in making microstructures in the work piece.