Patents by Inventor Alan Daniel

Alan Daniel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted Triazole Derivatives As Oxytocin Antagonists
    Publication number: 20130137671
    Abstract: The present invention relates to substituted triazoles of formula (I), uses thereof, processes for the preparation thereof and compositions containing said compounds. These inhibitors have utility in a variety of therapeutic areas including sexual dysfunction.
    Type: Application
    Filed: May 23, 2012
    Publication date: May 30, 2013
    Inventors: Alan Daniel Brown, Andrew Antony Calabrese, David Ellis
  • Chemical Compounds
    Publication number: 20130116285
    Abstract: The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula 10 (I):(I) or a pharmaceutically acceptable salt thereof, wherein Z, R1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.
    Type: Application
    Filed: July 6, 2011
    Publication date: May 9, 2013
    Applicant: Pfizer Limited
    Inventors: Andrew Simon Bell, Alan Daniel Brown, Russell Andrew Lewthwaite, Manuel Perez-Pacheco, David James Rawson, Robert Ian Storer, Nigel Alan Swain
  • Chemical Compounds
    Publication number: 20130109708
    Abstract: The invention relates to sulfonamide derivatives, to their use in medicine, to 5 compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I):10 X NH O S O O R1 R2 R5 R4 R3 Het1 (I) or a pharmaceutically acceptable salt thereof, wherein X, Het1, R1, R2, R3, R4 and R5 are as defined in the description. 15 Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.
    Type: Application
    Filed: July 4, 2011
    Publication date: May 2, 2013
    Applicant: Pfizer Limited
    Inventors: Alan Daniel Brown, David James Rawson, Robert Ian Storer, Nigel Alan Swain
  • Chemical Compounds
    Publication number: 20130109701
    Abstract: The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfon-amide Nav1.7 inhibitors of formula (I): or a pharmaceutically acceptable salt thereof, wherein X, Ar1, R1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.
    Type: Application
    Filed: July 4, 2011
    Publication date: May 2, 2013
    Applicant: Pfizer Limited
    Inventors: Alan Daniel Brown, David James Rawson, Robert Ian Storer, Nigel Alan Swain
  • IGE CH3 Peptide Vaccine
    Publication number: 20120294848
    Abstract: The present invention relates to the provision of novel immunogens comprising an antigenic IgE peptide preferably linked to an immunogenic carrier for the prevention, treatment or alleviation of IgE-mediated disorders. The invention further relates to methods for production of these medicaments, immunogenic compositions and pharmaceutical compositing thereof and their use in medicine.
    Type: Application
    Filed: August 1, 2012
    Publication date: November 22, 2012
    Applicant: PFIZER VACCINES LLC
    Inventors: Alan Daniel Brown, Brian Robert Champion, Clare Christy, David Paul Gervais, Lyn Howard Jones, Anne Maria Kristina Kjerrstrom, David Cameron Pryde, Lee Richard Roberts, David Michael Wyatt
  • IgE CH3 peptide vaccine
    Patent number: 8298547
    Abstract: The present invention relates to the provision of novel immunogens comprising an antigenic IgE peptide preferably linked to an immunogenic carrier for the prevention, treatment or alleviation of IgE-mediated disorders. The invention further relates to methods for production of these medicaments, immunogenic compositions and pharmaceutical compositing thereof and their use in medicine.
    Type: Grant
    Filed: December 9, 2009
    Date of Patent: October 30, 2012
    Assignee: Pfizer Vaccines, LLC
    Inventors: Alan Daniel Brown, Brian Robert Champion, Clare Christy, David Paul Gervais, Lyn Howard Jones, Anne Maria Kristina Kjerrstrom, David Cameron Pryde, Lee Richard Roberts, David Michael Wyatt
  • WHEEL END WITH INTEGRATED MOTOR ASSEMBLY
    Publication number: 20120233992
    Abstract: A wheel end assembly comprises a wheel hub support housing and a wheel hub drive assembly rotatably connected to the wheel hub support housing. The wheel end assembly also includes a hydraulic motor operatively coupled to the wheel hub drive assembly, the hydraulic motor being disposed to deliver a torque to the wheel hub drive assembly. The wheel end assembly further includes a pump, fluidly coupled to the wheel hub drive assembly and the hydraulic motor, the pump being disposed to provide a flow of hydraulic fluid to the wheel hub drive assembly.
    Type: Application
    Filed: June 4, 2012
    Publication date: September 20, 2012
    Inventors: Norval Paul Thomson, Steven Alan Daniel, Daniel Peter Sergison, Avert Glen Vannette
  • Wheel end with integrated motor assembly
    Patent number: 8215430
    Abstract: A wheel end assembly comprises a wheel hub support housing and a wheel hub drive assembly rotatably connected to the wheel hub support housing. The wheel end assembly also includes a hydraulic motor operatively coupled to the wheel hub drive assembly, the hydraulic motor being disposed to deliver a torque to the wheel hub drive assembly. The wheel end assembly further includes a pump, fluidly coupled to the wheel hub drive assembly and the hydraulic motor, the pump being disposed to provide a flow of hydraulic fluid to the wheel hub drive assembly.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: July 10, 2012
    Assignee: Caterpillar Inc.
    Inventors: Norval Paul Thomson, Steven Alan Daniel, Daniel Peter Sergison, Avert Glen Vannette
  • Substituted triazole derivatives as oxytocin antagonists
    Patent number: 8207198
    Abstract: The present invention relates to substituted triazoles of formula (I), uses thereof, processes for the preparation thereof and compositions containing said compounds. These inhibitors have utility in a variety of therapeutic areas including sexual dysfunction.
    Type: Grant
    Filed: May 15, 2009
    Date of Patent: June 26, 2012
    Assignee: Pfizer Inc.
    Inventors: Alan Daniel Brown, Andrew Antony Calabrese, David Ellis
  • Melanocortin type 4 receptor agonist piperidinoylpyrrolidines
    Patent number: 8138188
    Abstract: The present invention relates to a class of melanocortin MCR4 agonists of general formula (I) wherein the variables and substituents are as defined herein and especially to selective MCR4 agonist compounds, to their use in medicine, particularly in the treatment of sexual dysfunction and obesity, to intermediates useful in their synthesis and to compositions containing them.
    Type: Grant
    Filed: February 19, 2007
    Date of Patent: March 20, 2012
    Assignee: Pfizer Inc.
    Inventors: Mark David Andrews, Alan Daniel Brown, Mark Ian Lansdell, Nicholas William Summerhill
  • Multi-bank memory device method and apparatus
    Patent number: 8120985
    Abstract: In one embodiment, a memory device comprises a semiconductor substrate, a first set of memory banks disposed on the semiconductor substrate and a second set of memory banks disposed on the semiconductor substrate. Each memory bank of the second set is split into a plurality of memory bank segments physically separated from each other and from the first set of memory banks. Each memory bank segment is arranged adjacent to, and occupies less area than, one of the memory banks of the first set.
    Type: Grant
    Filed: March 12, 2008
    Date of Patent: February 21, 2012
    Assignee: Qimonda AG
    Inventors: Christopher Kunce, Benjamin Heilmann, Alan Daniel
  • Chemical Compounds
    Publication number: 20120010182
    Abstract: The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to new sulfonamide Nav1.7 inhibitors of formula (I): or pharmaceutically acceptable salts thereof, wherein Z1, Ra, Rb, R1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.
    Type: Application
    Filed: July 8, 2011
    Publication date: January 12, 2012
    Applicants: ICAGEN INC., PFIZER LIMITED
    Inventors: Alan Daniel Brown, Marcel John De Groot, Brian Edward Marron, David James Rawson, Thomas Ryckmans, Robert Ian Storer, Paul Anthony Stupple, Nigel Alan Swain, Christopher William West
  • Chemical Compounds
    Publication number: 20120010207
    Abstract: The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I): or a pharmaceutically acceptable salt thereof, wherein Ar1, X, R1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.
    Type: Application
    Filed: July 11, 2011
    Publication date: January 12, 2012
    Applicant: PFIZER LIMITED
    Inventors: Andrew Simon Bell, Alan Daniel Brown, Russell Andrew Lewthwaite, Ian Roger Marsh, David Simon Millan, Manuel Perez Pacheco, David James Rawson, Nunzio Sciammetta, Robert Ian Storer, Paul Anthony Stupple, Nigel Alan Swain, Marcel John De Groot
  • Chemical Compounds
    Publication number: 20120010183
    Abstract: The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I): or a pharmaceutically acceptable salt thereof, wherein Het1, X, R1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.
    Type: Application
    Filed: July 11, 2011
    Publication date: January 12, 2012
    Applicant: PFIZER LIMITED
    Inventors: Andrew Simon Bell, Alan Daniel Brown, Marcel John De Groot, Russell Andrew Lewthwaite, Ian Roger Marsh, David Simon Millan, Manuel Perez Pacheco, David James Rawson, Nunzio Sciammetta, Robert Ian Storer, Nigel Alan Swain, Steven Matthieu Gaulier
  • CONJUGATES FOR THE PREVENTION OR TREATMENT OF NICOTINE ADDICTION
    Publication number: 20110300174
    Abstract: The present invention relates in part to nicotine-derived hapten-carrier conjugates of the formula (III): wherein m, n, W, -(spacer)-, X* and Y are as defined in the description. In certain embodiments, said nicotine-derived hapten-carrier conjugates can be used to prepare vaccines for the treatment and/or prevention of nicotine addiction.
    Type: Application
    Filed: June 2, 2011
    Publication date: December 8, 2011
    Applicant: Pfizer Vaccines LLC
    Inventors: Alan Daniel BROWN, Heather Lynn DAVIS, David P. GERVAIS, Lyn Howard JONES, James R. MERSON, David Cameron PRYDE, David R. STEAD, Michael J. MCCLUSKIE, Jennifer Marie THORN, Paul Robert MEHELIC, Parag Ashok KOLHE, Keshab BHATTACHARYA, Jari Ilmari FINNEMAN, Erin Kristen PARSONS, Nickolas ANASTASIOU
  • Composite material formed from foam filled honeycomb panel with top and bottom resin filled sheets
    Patent number: 8062728
    Abstract: A composite panel is formed from a honeycomb core panel with a foam material filling the tubular cells and a fibrous reinforcing cover sheets extending over the top and bottom of the panel. The cover sheets are filled with a set resin material which extends from the cover sheets into the porous fibrous material of the walls of the core panel so as to form an integral structure of the resin extending between the walls and the sheets.
    Type: Grant
    Filed: January 19, 2009
    Date of Patent: November 22, 2011
    Inventors: Alan Daniel De Baets, Paul J. Dagesse
  • Sulfonamide derivatives for the treatment of diseases
    Patent number: 8013019
    Abstract: The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
    Type: Grant
    Filed: July 1, 2010
    Date of Patent: September 6, 2011
    Assignee: Pfizer Inc
    Inventors: Alan Daniel Brown, Mark Edward Bunnage, Paul Alan Glossop, Kim James, Charlotte Alice Louise Lane, Russel Andrew Lewthwaite, Ian Brian Moses, David Anthony Price, Nicholas Murray Thomson
  • Method of forming solid vias in a printed circuit board
    Patent number: 7987587
    Abstract: A method is described by which an electrical path is created between layers on a printed circuit board (PCB) without the use of plated through holes (PTH). Through the use of a liquid solder or conductive epoxy injection fixture, a conductive path is created in pre-drilled holes forming an electrical connection between internal PCB metal layers and surface mounted components without the creation of parasitic stubs on the signal nets.
    Type: Grant
    Filed: March 7, 2008
    Date of Patent: August 2, 2011
    Assignee: International Business Machines Corporation
    Inventors: Wiren Dale Becker, Michael Ford McAllister, Alan Daniel Stigliani, John G. Torok
  • 1,2,4-Triazole Derivatives and Their Use as Oxytocin Antagonists
    Publication number: 20110092529
    Abstract: The present invention relates to a class of substituted triazoles of formula (I) with activity as oxytocin antagonists, uses thereof, processes for the preparation thereof and compositions containing said inhibitors. These inhibitors have utility in a variety of therapeutic areas including sexual dysfunction, particularly premature ejaculation (P.E.).
    Type: Application
    Filed: January 6, 2006
    Publication date: April 21, 2011
    Inventors: Alan Daniel Brown, Andrew Antony Calabrese, David Ellis
  • MESOPOROUS PARTICULATE MATERIALS
    Publication number: 20110086270
    Abstract: Relatively disordered mesoporous particulate materials have internal porosity, a surface area of 100 m2/g or greater with a network of pores characterised by a peak in the pore size distribution at a value between 2 and 20 nm and a ratio of the half-height width of the distribution's peak to the pore diameter axis position of the peak of at least 0.6.
    Type: Application
    Filed: February 27, 2009
    Publication date: April 14, 2011
    Inventors: Katherine Elizabeth Amos, Tobias James Gordon-Smith, Alan Daniel Spong