Abstract: A classifier engine provides cell morphology identification and cell classification in computer-automated systems, methods and diagnostic tools. The classifier engine performs multispectral segmentation of thousands of cellular images acquired by a multispectral imaging flow cytometer. As a function of imaging mode, different ones of the images provide different segmentation masks for cells and subcellular parts. Using the segmentation masks, the classifier engine iteratively optimizes model fitting of different cellular parts. The resulting improved image data has increased accuracy of location of cell parts in an image and enables detection of complex cell morphologies in the image. The classifier engine provides automated ranking and selection of most discriminative shape based features for classifying cell types.

Abstract: A classifier engine provides cell morphology identification and cell classification in computer-automated systems, methods and diagnostic tools. The classifier engine performs multispectral segmentation of thousands of cellular images acquired by a multispectral imaging flow cytometer. As a function of imaging mode, different ones of the images provide different segmentation masks for cells and subcellular parts. Using the segmentation masks, the classifier engine iteratively optimizes model fitting of different cellular parts. The resulting improved image data has increased accuracy of location of cell parts in an image and enables detection of complex cell morphologies in the image. The classifier engine provides automated ranking and selection of most discriminative shape based features for classifying cell types.

Abstract: A classifier engine provides cell morphology identification and cell classification in computer-automated systems, methods and diagnostic tools. The classifier engine performs multispectral segmentation of thousands of cellular images acquired by a multispectral imaging flow cytometer. As a function of imaging mode, different ones of the images provide different segmentation masks for cells and subcellular parts. Using the segmentation masks, the classifier engine iteratively optimizes model fitting of different cellular parts. The resulting improved image data has increased accuracy of location of cell parts in an image and enables detection of complex cell morphologies in the image. The classifier engine provides automated ranking and selection of most discriminative shape based features for classifying cell types.

Abstract: The methods and systems described herein attempt to address the above-mentioned need by providing an algorithm and software capability to automatically detect and assess “natural experiments” that exist in any underlying dataset. In one embodiment, a computer-implemented method for identifying an experiment to use in an analysis of a business initiative comprises storing, by a computer, a set of historical data regarding entities in a business network; receiving, by the computer, a selection of inputs for the historical data; detecting, by the computer, a natural experiment based upon changes in the discretized historical data; and outputting, by the computer, a report of a detected experiment from the discretized historical data.

Abstract: A classifier engine provides cell morphology identification and cell classification in computer-automated systems, methods and diagnostic tools. The classifier engine performs multispectral segmentation of thousands of cellular images acquired by a multispectral imaging flow cytometer. As a function of imaging mode, different ones of the images provide different segmentation masks for cells and subcellular parts. Using the segmentation masks, the classifier engine iteratively optimizes model fitting of different cellular parts. The resulting improved image data has increased accuracy of location of cell parts in an image and enables detection of complex cell morphologies in the image. The classifier engine provides automated ranking and selection of most discriminative shape based features for classifying cell types.

Abstract: The methods and systems described herein attempt to address the above-mentioned need by providing an algorithm and software capability to automatically detect and assess “natural experiments” that exist in any underlying dataset. In one embodiment, a computer-implemented method for identifying an experiment to use in an analysis of a business initiative comprises storing, by a computer, a set of historical data regarding entities in a business network; receiving, by the computer, a selection of inputs for the historical data; detecting, by the computer, a natural experiment based upon changes in the historical data; and outputting, by the computer, a report of a detected experiment from the historical data.

Abstract: According to an example aspect of the present invention, there is provided a paper cup comprising: a base; a sidewall; said base and said sidewall together defining a space for receiving liquid or food; an upper end portion of the cup comprising a first and second pair of opposing closure panels, whereby each panel is attached to an upper edge of the sidewall via a respective first folding line and to adjacent panels via respective second folding lines. Said panels are foldable into a closed position to form a lid of the cup. Each panel of said first pair contains two additional folding lines to enable folding inwards. Upon folding to the closed position, a first panel of said second pair is partly inserted below a second panel of said second pair, and the panels of said second pair close the upper end portion.

Abstract: The methods and systems described herein attempt to address the above-mentioned need by providing an algorithm and software capability to automatically detect and assess “natural experiments” that exist in any underlying dataset. In one embodiment, a computer-implemented method for identifying an experiment to use in an analysis of a business initiative comprises storing, by a computer, a set of historical data regarding entities in a business network; receiving, by the computer, a selection of inputs for the historical data; detecting, by the computer, a natural experiment based upon changes in the historical data; and outputting, by the computer, a report of a detected experiment from the historical data.

Abstract: A classifier engine provides cell morphology identification and cell classification in computer-automated systems, methods and diagnostic tools. The classifier engine performs multispectral segmentation of thousands of cellular images acquired by a multispectral imaging flow cytometer. As a function of imaging mode, different ones of the images provide different segmentation masks for cells and subcellular parts. Using the segmentation masks, the classifier engine iteratively optimizes model fitting of different cellular parts. The resulting improved image data has increased accuracy of location of cell parts in an image and enables detection of complex cell morphologies in the image. The classifier engine provides automated ranking and selection of most discriminative shape based features for classifying cell types.

Abstract: According to an example aspect of the present invention, there is provided a paper cup comprising: a base; a sidewall; said base and said sidewall together defining a space for receiving liquid or food; an upper end portion of the cup comprising a first and second pair of opposing closure panels, whereby each panel is attached to an upper edge of the sidewall via a respective first folding line and to adjacent panels via respective second folding lines. Said panels are foldable into a closed position to form a lid of the cup. Each panel of said first pair contains two additional folding lines to enable folding inwards. Upon folding to the closed position, a first panel of said second pair is partly inserted below a second panel of said second pair, and the panels of said second pair close the upper end portion.

Abstract: According to an example aspect of the present invention, there is provided a paper cup comprising: a base; a sidewall; said base and said sidewall together defining a space for receiving liquid or food; an upper end portion of the cup comprising a first and second pair of opposing closure panels, whereby each panel is attached to an upper edge of the sidewall via a respective first folding line and to adjacent panels via respective second folding lines. Said panels are foldable into a closed position to form a lid of the cup. Each panel of said first pair contains two additional folding lines to enable folding inwards. Upon folding to the closed position, a first panel of said second pair is partly inserted below a second panel of said second pair, and the panels of said second pair close the upper end portion.

Abstract: Presented systems and methods facilitate efficient reset operation. In one embodiment, a system comprises a core domain portion an I/O domain portion and a core reset I/O by-pass component. The core domain portion is configured to operate at a nominal core domain voltage level. The I/O domain portion configured to operate at a nominal I/O domain voltage level. The core reset I/O by-pass component configured to forward a reset indication to the core domain independent of the I/O domain. In one exemplary implementation the core reset I/O by-pass component is operable to receive an input reset indication at a high domain voltage level and to convert the input reset indication to a core reset signal that is less than or substantially equal to the nominal core domain voltage, wherein the high domain is voltage higher than the core domain voltage level.

Abstract: The present invention provides a carton for a bag in box packaging. The carton has the overall configuration of a rectangular parallelepiped, with two pairs of opposing sidewalls and an upper end portion and a lower end portion, together defining a cavity for receiving a liquid holding bag. In the lower end portion there are a first pair of opposing flaps and a second pair of opposing flaps. The carton further has an opening extending through one sidewall in the lower end portion for dispensing liquid from a bag positioned inside the cavity. According to the invention the first pair of opposing flaps are foldable into an open position, in which the flaps extend outwards from the cavity to form a pair of legs. The legs are interlockable with a flap of said second pair of flaps so as firmly to fix the position of the legs with regard to the carton. The leg-forming flaps support the carton in an elevated position with respect to a surface thus facilitating dispension of liquid through the opening.

Abstract: The present invention provides a carton for a bag in box packaging. The carton has the overall configuration of a rectangular parallelepiped, with two pairs of opposing sidewalls and an upper end portion and a lower end portion, together defining a cavity for receiving a liquid holding bag. In the lower end portion there are a first pair of opposing flaps and a second pair of opposing flaps. The carton further has an opening extending through one sidewall in the lower end portion for dispensing liquid from a bag positioned inside the cavity. According to the invention the first pair of opposing flaps are foldable into an open position, in which the flaps extend outwards from the cavity to form a pair of legs. The legs are interlockable with a flap of said second pair of flaps so as firmly to fix the position of the legs with regard to the carton. The leg-forming flaps support the carton in an elevated position with respect to a surface thus facilitating dispension of liquid through the opening.

Abstract: Presented systems and methods facilitate efficient reset operation. In one embodiment, a system comprises a core domain portion an I/O domain portion and a core reset I/O by-pass component. The core domain portion is configured to operate at a nominal core domain voltage level. The I/O domain portion configured to operate at a nominal I/O domain voltage level. The core reset I/O by-pass component configured to forward a reset indication to the core domain independent of the I/O domain. In one exemplary implementation the core reset I/O by-pass component is operable to receive an input reset indication at a high domain voltage level and to convert the input reset indication to a core reset signal that is less than or substantially equal to the nominal core domain voltage, wherein the high domain is voltage higher than the core domain voltage level.

Abstract: Presented systems and methods facilitate efficient reset operation. In one embodiment, a system comprises a core domain portion an I/O domain portion and a core reset I/O by-pass component. The core domain portion is configured to operate at a nominal core domain voltage level. The I/O domain portion configured to operate at a nominal I/O domain voltage level. The core reset I/O by-pass component configured to forward a reset indication to the core domain independent of the I/O domain. In one exemplary implementation the core reset I/O by-pass component is operable to receive an input reset indication at a high domain voltage level and to convert the input reset indication to a core reset signal that is less than or substantially equal to the nominal core domain voltage, wherein the high domain is voltage higher than the core domain voltage level.

Abstract: Presented systems and methods facilitate efficient reset operation. In one embodiment, a system comprises a core domain portion an I/O domain portion and a core reset I/O by-pass component. The core domain portion is configured to operate at a nominal core domain voltage level. The I/O domain portion configured to operate at a nominal I/O domain voltage level. The core reset I/O by-pass component configured to forward a reset indication to the core domain independent of the I/O domain. In one exemplary implementation the core reset I/O by-pass component is operable to receive an input reset indication at a high domain voltage level and to convert the input reset indication to a core reset signal that is less than or substantially equal to the nominal core domain voltage, wherein the high domain is voltage higher than the core domain voltage level.