Abstract: The present invention relates to an immunogenic polypeptide isolated from Mycobacterium avium subspecies paratuberculosis and variants of the polypeptide. The polypeptide and variants may be used in vaccines against Johne's disease and in methods for detection of the disease. Antibodies against the polypeptide or variants may be used in diagnostic tests for Johne's disease. Also included are polynucleotides encoding the polypeptide and variants, and methods for preparing these.

Abstract: A new system including circuit and methods are given to realize a dynamic matching of current sources, which are arranged as arrays of sets of current sources with added piecewise switchable trim bit transistors. The matching is achieved during an programmed calibration and trimming step by switching ON/OFF certain trim bit transistors until a required accuracy compared to a master reference is reached. The accuracy of the current source trimming is purely a function of the LSB size, and the trim range a function of the number of trim bits. Applying these new principles the drawbacks with regard to chip space and cost of prior art solutions can be overcome. Making use of modern chip manufacturing technologies allows for a very flexible and adaptive production of large arrays of current sources, as e.g. used in driver ICs for OLED displays.

Abstract: The invention provides a vaccine comprising secreted protein derived from Mycobacterium avium subsp paratuberculosis (M. ptb) substantially free of whole organisms of that species either dead or alive. The secreted protein may be obtained from a culture of M. ptb with the microorganisms being removed by centrifugation and subsequent filtration.

Abstract: The invention provides a vaccine comprising secreted protein derived from Mycobacterium avium subsp paratuberculosis (M. ptb) substantially free of whole organisms of that species either dead or alive. The secreted protein may be obtained from a culture of M. ptb with the microorganisms being removed by centrifugation and subsequent filtration. The vaccine may be used for vaccination against Johne's disease.

Abstract: The present invention relates to an immunogenic polypeptide isolated from Mycobacterium avium subspecies paratuberculosis and variants of the polypeptide. The polypeptide and variants may be used in vaccines against Johne's disease and in methods for detection of the disease. Antibodies against the polypeptide or variants may be used in diagnostic tests for Johne's disease. Also included are polynucleotides encoding the polypeptide and variants, and methods for preparing these.

Abstract: A pneumatic radial ply tire (500) comprises a tread (510), a belt structure (512), and a carcass (514). The carcass (514) has a radial ply (518) and two bead sections (530A, 530B). Each bead section (530A, 530B) has a bead (532) and a component apex (534) with a inner apex (534A), a middle apex (534B) and an outer apex (534C).

Abstract: The invention provides a vaccine comprising secreted protein derived from Mycobacterium avium subsp paratuberculosis (M. ptb) substantially free of whole organisms of that species either dead or alive. The secreted protein may be obtained from a culture of M. ptb with the microorganisms being removed by centrifugation and subsequent filtration. The vaccine may be used for vaccination against Johne's disease.

Abstract: The disclosed roller switch has a roller, a flag arm, and a photoelectric detector. The roller is connected to the flag arm and vertical movement of the roller causes the flag arm to move. The movement of the flag arm causes the photoelectric detector to send a signal. The signal may be used to measure the length of a material passing under the roller. The inventive roller switch has a pair of flag arms, and the roller is mounted on a shaft extending between the pair of flag arms. By providing a pair of flag arms connected by the roller, the roller switch is more robust and durable. The roller switch is also capable of pivoting across a conveyor belt.

Abstract: A subsea wellhead assembly has the capabilities of communicating from the outer surface of an outer wellhead housing to a casing annulus. Seals between the outer and inner wellhead housings define an annular chamber when the inner wellhead housing lands. The outer wellhead housing has a communication port formed through one of its sidewalls. The inner wellhead housing has a passageway extending from the annular chamber to the bore of the inner wellhead housing. The casing annulus located radially inward of the inner wellhead housing is in communication with the outer surface of the outer wellhead housing through the passageway, the annular chamber between the seals, and the communication port.

Abstract: Apparatus for automatic recognition of a target object from an infrared or visible light image, includes primary segmentation and classification means (4,8,9,10,11,12) in which objects are either recognised or unrecognised and one or more secondary segmentation means (15,21,22,23,12) applicable to primary segmented image areas in which objects which are unrecognised by the primary segmentation means are further classified and either recognised or rejected.

Abstract: A subsea wellhead assembly has the capabilities of communicating from the outer surface of an outer wellhead housing to a casing annulus. Seals between the outer and inner wellhead housings define an annular chamber when the inner wellhead housing lands. The outer wellhead housing has a communication port formed through one of its sidewalls. The inner wellhead housing has a passageway extending from the annular chamber to the bore of the inner wellhead housing. The casing annulus located radially inward of the inner wellhead housing is in communication with the outer surface of the outer wellhead housing through the passageway, the annular chamber between the seals, and the communication port.

Abstract: The disclosed roller switch has a roller, a flag arm, and a photoelectric detector. The roller is connected to the flag arm and vertical movement of the roller causes the flag arm to move. The movement of the flag arm causes the photoelectric detector to send a signal. The signal may be used to measure the length of a material passing under the roller. The inventive roller switch has a pair of flag arms, and the roller is mounted on a shaft extending between the pair of flag arms. By providing a pair of flag arms connected by the roller, the roller switch is more robust and durable. The roller switch is also capable of pivoting across a conveyor belt.

Abstract: In order to reduce bias associated with conventional ECG analysis, the present invention provides a method and apparatus to improve diagnosis of acute cardiac syndromes (ACS), such as acute myocardial infarction and acute cardiac ischemia (unstable angina), in specified groups of patients using ECG signals and automatic detection analysis. Specific criteria are developed and utilized based on a prespecified group selection for the particular patient. After identifying group membership for the particular patient, ECG data are acquired from a patient experiencing ACS symptoms. Known criteria typically used for assessing ACS are then modified for the particular group membership. Such criteria significantly reduce the bias found in a baseline group for which the known criteria were established.

Abstract: A conveyor assembly and method for conveying and storing a strip material in a conveyor system that is subject to changes in length of the strip material due to intermittent operation includes an upper conveyor (16), an adjustable substantially horizontal center conveyor (22) for receiving the strip material (34) from the upper conveyor, and a lower conveyor (28) for receiving the associated strip material from the center conveyor. A computer (94) controls the movement and rotation of the center conveyor, and loop detecting apparatus on the center conveyor may also detect a loop (90) in the strip material carried by the center conveyor and thereby detecting changes in length of the strip material not predetermined by the computer. A servomechanism (100) activated by signals from the computer or the loop detecting apparatus moves the center conveyor in a substantially horizontal direction.

Abstract: A method and system for secure transactions. The method and system comprise a security co-processor and an interface for interfacing the security co-processor to a host computer system. The method and system wherein secure transaction processing is performed locally in the security co-processor and non-secure transaction processing is performed in the host computer system. The method and system further include means for providing trusted input coupled to the security co-processor. In addition, the method and system include a second interface coupled to the security co-processor for receiving sensitive data from a smart card, and a trusted display coupled to the security co-processor for providing true transaction information. One advantage of the method and system in accordance with the present invention is that transactions are protected from unauthorized intrusion and, in addition, participation is proven so that transactions cannot be repudiated.

Abstract: A conveyor system and method for steering and shifting an associated strip component to a desired transverse position includes a sensor for sensing the transverse position of the associated strip component, a shaft rotatable about an axis generally perpendicular to the direction of motion of the strip component, and a plurality of guide disks rotatably mounted on side by side sleeve bearings which are keyed to the shaft. Each of the guide disks has an inner circumferential bearing surface and an outer circumferential surface for engagement with the bottom surface of the associated strip component. Each of the guide disks is canted at a fixed angle with respect to the shaft axis. Additionally the shaft is axially movable.

Abstract: The invention relates to a nucleotide sequence which is present at a position adjacent to the 5' end of the reverse sequence complementary to the open reading frame coding for a potential transposase contained in the insertion element IS900 in Mycobacterium paratuberculosis. The nucleotide sequence has promoter functions and contains important signals for the regulation of transcription and translation. The invention also relates to methods for cloning and expressing heterologous proteins using such regulatory sequences, to vectors and transformed host cells containing these sequences, and to immunogenic compositions prepared by expression of nucleotide sequences placed under control of these regulatory sequences.

Abstract: An extruder for extruding an associated material includes an extruder housing that has a feed section, a center section that includes a throttle section, and an outlet section with an extruder screw disposed in the extruder housing. The extruder also includes a throttle at the throttle section. The throttle has a plurality of pins that extend radially into the housing. The pins are adjusted by a cam extending around the extruder housing. The cam has an inner wall that has a plurality of cam surfaces engageable by pins. The radius of each of the cam surfaces gradually decreases from a maximum radius to a minimum radius distance. The pins have springs that urge the pins radially outward to contact the inner wall of the cam. The cam is rotated by a piston and cylinder assembly. The extruder further includes sensors for temperature, gauge, weight, and other properties of the material.

Abstract: A mobile irradiation device for providing either energetic electrons or short wavelength photons, i.e., gamma ray and/or x-rays has a photocathode, a laser for illuminating the photocathode and a radio-frequency electron gun for accelerating electrons emitted from the laser illuminated photocathode. A quadrupole magnet triple facilitates focusing of energetic electrons onto the target or the material to be irradiated.

Abstract: A vessel for the long term storage and monitoring of nuclear fuel materials incorporates a device (12) within its interior for providing an externally detectable signal indicating whether any pressure loss has occurred. The device (12) comprises a magnet (32) attracted towards a boundary wall (11) of the vessel and urged in that direction by the internal pressure within the vessel acting on a diaphragm (26). The magnet (32) is subjected to oppositely directed forces by pressurized fluid in chamber (40) bounded by diaphragm (26) and a spring (30), the arrangement being such that these latter forces collectively or individually are effective to drive the magent (32) away from the wall (11) in the event of a pressure loss within the vessel thereby producing an externally detectable change in magnetic flux.