Abstract: The disclosed computer-implemented method may include (i) associating a planar element within a virtual environment with an alternate virtual environment and (ii) rendering the virtual environment such that (A) the alternate virtual environment is framed within the planar element, (B) at least one rendered element of the alternate virtual environment renders at a distal depth beyond a proximal depth of the planar element within the virtual environment, and (C) altering a viewpoint within the virtual environment relative to a position of the planar element within the virtual environment produces a parallax effect between the virtual environment and the rendered element of the alternate virtual environment due at least in part to the rendered element of the alternate virtual environment being rendered at the distal depth beyond the proximal depth of the planar element within the virtual environment. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: A communication system has a plurality of LEO satellites in a specified orbital plane and a plurality of trunk satellites in a medium earth orbit. Each LEO satellite acquires satellite-specific data and includes inter-satellite links with adjacent LEO satellites. Each trunk satellite includes inter-satellite links adjacent trunk satellites. One of the trunk satellites operates as a relay trunk satellite in position to maintain optical communication with a specified ground station on the Earth. Each LEO satellite has a limited field of regard to establish optical communication with any trunk satellite. A relay LEO satellite is configured to establish optical communication with a corresponding trunk satellite. The plurality of LEO satellites relay aggregated data to the relay LEO satellite. The relay LEO satellite relays the aggregated data to the corresponding trunk satellite. The relay trunk satellite relays the received aggregated data to the corresponding ground station.

Abstract: A method and system for initiating message listening and routing message content to authorized user devices is disclosed. For a second user device to receive notifications regarding records of a first user, the second user device provides information identifying the first user to a notification service. The notification service verifies the identifying information. The notification service initiates one or more listeners to listen for messages flowing over a messaging bus that are relating to the first user. Once a message is identified, at least a portion of the message is used to generate a notification that may be sent to the second user device.

Abstract: A clock monitor circuit detects departures from expected values for clock period, clock high time duration, or clock low time duration. A delay line of the clock monitor circuit is composed of delay portions of delay cells. Each delay cell also has a comparator portion with logic to compare aspects of the monitored clock signal to corresponding expected values, and to output a failure detection signal indicating whether the expected values are met. Expected values may be read from a fuse set. The delay of the delay line may be programmatically adjusted. The clock monitor circuit may be combined with a circuit that detects narrow glitches in the monitored clock signal. Devices and systems with one or more monitored clock signals, and methods of clock signal monitoring, are also described.

Abstract: The present application describes an apparatus a non-transitory memory having instructions stored thereon and a processor operably coupled to the non-transitory memory configured to execute the instructions. The executed instructions include extracting eigenvalues for a coupling matrix of a target device. The executed instructions also include extracting a first set of eigenvalues for a coupling matrix of a device under tune (DUT). The eigenvalues of the target device may be different than the first set of eigenvalues of the DUT. The executed instructions further include causing a material removal source to be positioned at a first location of the DUT. The executed instructions even further include causing the material removal source to tune the DUT. The executed instructions yet further include measuring a second set of eigenvalues of the DUT. The executed instructions yet even further include observing an iterative convergence of the DUT and the target device.

Abstract: The present invention relates to compositions and methods of inhibiting p38 kinase to reduce gene and protein expression of DUX4 and downstream genes regulated by DUX4. The present invention further relates to methods for treating patients suffering from diseases associated with increased expression of DUX4 or expression of an aberrant form of DUX4, such as Facioscapulohumeral muscular dystrophy (FSHD).

Abstract: Systems, methods, and machine-readable media for process-performing resources and process specifications particularized to loads are provided. A provisional electronic composite for a load may be created. A type of process-performing resource may be identified. Performance data may be accessed to identify a process-performance duration that corresponds to a process type, the type of process-performing resource, process-performance locations, and process-performance times. A process-assignment duration may be defined, and an availability of a process-performing resource may be detected. A performance time may be determined based on the availability of the process-performing resource. Instruction to perform the process at the performance time may transmitted to at least one resource-controlling device. The provisional electronic composite for the load may be modified based on the performance time and the instruction to form an updated electronic composite.

Abstract: The disclosure relates to methods and compositions including p38 kinase inhibitors and agents that regulate expression of DUX4 and downstream genes including but not restricted to ZSCAN4, LEUTX, PRAMEF2, TRIM43, MBD3L2, KHDC1L, RFPL2, CCNA1, SLC34A2, TPRX1, PRAMEF20, TRIM49, PRAMEF4, PRAME6, PRAMEF15, or ZNF280A. Methods useful for treating a disease associated with abnormal DUX4 and downstream gene expression (e.g., Fascioscapulohumeral muscular dystrophy) are disclosed.

Abstract: The present application describes a method of tuning a printed device. The method includes measuring a frequency response of a target device and a device under tune (DUT). The method includes computing, based on the measured frequency response, a coupling matrix for the target device and a coupling matrix for the DUT. The method also includes extracting eigenvalues for the coupling matrix of the target device and a first set of eigenvalues for the coupling matrix of the DUT. The eigenvalues of the target device are different than the first set of eigenvalues of the DUT. The method further includes tuning the DUT with a material removal source. The method even further includes measuring a second set of eigenvalues of the DUT. The second set of eigenvalues is different from the first set of eigenvalues of the DUT. The method yet even further includes calculating a tune path for iterative convergence of the second or a subsequent set of eigenvalues of the DUT with the eigenvalues of the target device.

Abstract: A system for dispensing sterile covers for a stethoscope or other medical device, including a container including elongated members positioned in the container, terminating at tips proximate one end of the container; one or more collapsed pouches positioned inside the container, each pouch having open and closed ends and retainers, each retainer adapted to receive a corresponding elongated member, the collapsed pouches being supported on the elongated members; each pouch comprising a tab positioned proximate the open end for being grasped and pulled in a direction away and downwards from the elongated members, the open end forming an open position defined by the retainers and the tab for receiving a head of the stethoscope inside the pouch while the retainers remain engaged with the elongated members; after use, the pouch is removable from the stethoscope without a user contacting a patient contacting region of the cover.

Abstract: This disclosure relates to the processing of data streams. More specifically, application of particular protocols to a stream and a detection analysis facilitate a selective, reliable and efficient transmission of pertinent stream data to destination addresses.

Abstract: An optical system includes a plurality of internal apertures, a plurality of external optical assemblies and a telescope assembly positioned between the plurality of internal apertures and the plurality of external optical assemblies. Each internal aperture is operable to receive a corresponding aperture-specific optical signal. Each external optical assembly corresponds to one of the internal apertures, and each external optical assembly is operable to direct the aperture-specific optical signal of the corresponding internal aperture in a corresponding external direction. The external direction for each external optical assembly is independently controllable and the telescope assembly defines a shared optical train arranged to direct the aperture-specific optical signals between each internal aperture and the corresponding external optical assembly.

Abstract: A method for assessing completion of events in a network environment is provided. The method includes receiving a first event vector, generating a second event vector, machine matching the first event vector to the second event vector, and generating an output that includes a variable indicating whether an event corresponding to the first event vector is complete. If each of a plurality of first nodes of the first event vector matches a corresponding one of a plurality of the second nodes of the second event vector, the variable indicates that the event corresponding to the first event vector is complete. If at least one of the plurality of the first nodes of the first event vector is mismatched with the corresponding one of the plurality of the second nodes of the second event vector, the variable indicates that the event corresponding to the first event vector is incomplete.

Abstract: A system for dispensing sterile covers for a stethoscope or other medical device, including a container including elongated members positioned in the container, terminating at tips proximate one end of the container; one or more collapsed pouches positioned inside the container, each pouch having open and closed ends and retainers, each retainer adapted to receive a corresponding elongated member, the collapsed pouches being supported on the elongated members; each pouch comprising a tab positioned proximate the open end for being grasped and pulled in a direction away and downwards from the elongated members, the open end forming an open position defined by the retainers and the tab for receiving a head of the stethoscope inside the pouch while the retainers remain engaged with the elongated members; after use, the pouch is removable from the stethoscope without a user contacting a patient contacting region of the cover.

Abstract: The disclosure relates to methods and compositions including p38 kinase inhibitors and agents that regulate expression of DUX4 and downstream genes including but not restricted to ZSCAN4, LEUTX, PRAMEF2, TRIM43, MBD3L2, KHDC1L, RFPL2, CCNA1, SLC34A2, TPRX1, PRAMEF20, TRIM49, PRAMEF4, PRAME6, PRAMEF15, or ZNF280A. Methods useful for treating a disease associated with abnormal DUX4 and downstream gene expression (e.g., Fascioscapulohumeral muscular dystrophy) are disclosed.

Abstract: The disclosure relates to methods and compositions including p38 kinase inhibitors and agents that regulate expression of DUX4 and downstream genes including but not restricted to ZSCAN4, LEUTX, PRAMEF2, TRIM43, MBD3L2, KHDC1L, RFPL2, CCNA1, SLC34A2, TPRX1, PRAMEF20, TRIM49, PRAMEF4, PRAME6, PRAMEF15, or ZNF280A. Methods useful for treating a disease associated with abnormal DUX4 and downstream gene expression (e.g., Fascioscapulohumeral muscular dystrophy) are disclosed.

Abstract: A portable imaging apparatus and system. A sample processing device has a reaction chamber configured to receive a sample and react the sample with a fluorescent compound that emits a specified wavelength of light when excited by light within an excitation band. An illumination source can be positioned to illuminate the reaction chamber when the sample processing device is positioned for imaging. A light guide can be positioned to face the reaction chamber and transfer the emitted light to an imaging detector. The light guide has a filter that blocks the wavelength of light from the illumination source and passes the fluorescent emitted light. The light guide unit defines an angular light acceptance range and is configured to constrain angular spreading of light.

Abstract: This disclosure relates to the processing of data streams. More specifically, application of particular protocols to a stream and a detection analysis facilitate a selective, reliable and efficient transmission of pertinent stream data to destination addresses.

Abstract: A method of treatment of skin tissue with two laser devices of unequal wavelengths comprising the steps of: (1) activating the two laser devices simultaneously to produce two laser beams of unequal wavelength; (2) directing the two laser beams into a handpiece having a distal tip to direct the laser beams onto the skin tissue; (3) directing the two laser beams within the handpiece to an adjustable beam deflector; and, (4) the adjustable beam deflector directing the two laser beams onto the skin tissue to produce a pattern of laser spots simultaneously but separated from one another.

Abstract: An accessory mounting device for removably mounting an accessory or fixture to a wall, ceiling, or other supporting surface. The device includes a bracket or clip which is affixable to the wall or other surface. The device further includes a cover which releasably mounts to the bracket or clip. The cover is configured to support and anchor various accessories and devices to the wall, ceiling, or other surface. The cover is mounted to and removed from the bracket by overcoming a biasing force provided between members of the bracket.