Patents by Inventor Alan T. Johnson, Jr.

Alan T. Johnson, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170299602
    Abstract: The present invention provides biomimetic sensor devices that utilize proteins—such G-protein coupled receptors—and are useful in high-sensitivity analysis of analyte-containing samples. These sensors may be used to determine the presence or concentration of one or more analytes in a sample. The invention also includes methods of fabricating the devices and methods of using the devices to assay samples.
    Type: Application
    Filed: November 16, 2016
    Publication date: October 19, 2017
    Inventors: Alan T Johnson, Jr., Brett R Goldsmith, Joseph J Mitala, Jr., Bohdana Discher, Stephen G Sligar, Timothy H Bayburt
  • Patent number: 9612240
    Abstract: The present invention provides biomimetic sensor devices that utilize proteins—such as G-protein coupled receptors—and are useful in high-sensitivity analysis of analyte-containing samples. These sensors may be used to determine the presence or concentration of one or more analytes in a sample. The invention also includes methods of fabricating the devices and methods of using the devices to assay samples.
    Type: Grant
    Filed: June 29, 2011
    Date of Patent: April 4, 2017
    Assignee: The Trustees Of The University Of Pennsylvania
    Inventors: Alan T. Johnson, Jr., Brett R. Goldsmith, Joseph J. Mitala, Jr., Bohdana Discher, Stephen G. Sligar, Timothy H. Bayburt
  • Patent number: 9053941
    Abstract: Methods for the fabrication of nanostructures, including nanostructures comprised of carbon nanotubes, and the nanostructures, devices, and assemblies prepared by these methods, are described.
    Type: Grant
    Filed: May 7, 2010
    Date of Patent: June 9, 2015
    Assignee: The Trustees Of The University Of Pennsylvania
    Inventors: Alan T. Johnson, Jr., Ryan A. Jones, Samuel M. Khamis
  • Publication number: 20150119263
    Abstract: Disclosed are devices that comprise a protein, such as an antibody, placed into electronic communication with a semiconductor material, such as a carbon nanotube. The devices are useful in assessing the presence or concentration of analytes contacted to the devices, including the presence of markers for prostate cancer and Lyme disease.
    Type: Application
    Filed: August 30, 2012
    Publication date: April 30, 2015
    Applicants: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, FOX CHASE CANCER CENTER
    Inventors: Alan T. Johnson, JR., Mitchell Lerner, Matthew K. Robinson, Tatiana Pazina, Dustin Brisson, Jennifer Dailey
  • Publication number: 20150065363
    Abstract: The present invention provides biomimetic sensor devices that utilize proteins—such as G-protein coupled receptors—and are useful in high-sensitivity analysis of analyte-containing samples. These sensors may be used to determine the presence or concentration of one or more analytes in a sample. The invention also includes methods of fabricating the devices and methods of using the devices to assay samples.
    Type: Application
    Filed: June 29, 2011
    Publication date: March 5, 2015
    Applicant: the Trustees of The University of Pennsylvania
    Inventors: Alan T. Johnson, JR., Brett R. Goldsmith, Joseph J. Mitala, JR., Bohdana Discher, Stephen G. Sligar, Timothy H. Bayburt
  • Patent number: 8918152
    Abstract: Disclosed are devices comprising multiple nanogaps having a separation of less than about 5 nm. Also disclosed are methods for fabricating these devices.
    Type: Grant
    Filed: February 13, 2008
    Date of Patent: December 23, 2014
    Assignee: The Trustees Of The University Of Pennsylvania
    Inventors: Douglas R. Strachan, Danvers E. Johnston, Beth S. Guiton, Peter K. Davies, Dawn A. Bonnell, Alan T. Johnson, Jr.
  • Publication number: 20140308682
    Abstract: Provided are devices and methods featuring a nanoelectronic interface between graphene devices (for example, field effect transistors or FETs) and biomolecules such as proteins, which in turn provides a pathway for production of bioelectronic devices that combine functionalities of the biomolecular and inorganic components. In one exemplary application, one may functionalize graphene FETs with fluorescent proteins to yield hybrids that respond to light at wavelengths defined by the optical absorption spectrum of the protein. The devices may also include graphene in electronic communication with a biomolecule that preferentially binds to a particular analyte.
    Type: Application
    Filed: November 20, 2012
    Publication date: October 16, 2014
    Applicant: The Trustees of The University of Pennsylvania
    Inventors: Alan T. Johnson, JR., Ye Lu, Joseph J. Mitala, Bohdana Discher
  • Patent number: 8609025
    Abstract: Chemical field effect sensors comprising nanotube field effect devices having biopolymers such as single stranded DNA or RNA functionally adsorbed to the nanotubes are provided. Also included are arrays comprising the sensors and methods of using the devices to detect volatile compounds.
    Type: Grant
    Filed: July 13, 2007
    Date of Patent: December 17, 2013
    Assignee: The Trustees of The University of Pennsylvania
    Inventor: Alan T. Johnson, Jr.
  • Publication number: 20120129273
    Abstract: Methods for the fabrication of nanostructures, including nanostructures comprised of carbon nanotubes, and the nanostructures, devices, and assemblies prepared by these methods, are described.
    Type: Application
    Filed: May 7, 2010
    Publication date: May 24, 2012
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: Alan T. Johnson, JR., Ryan A. Jones, Samuel M. Khamis
  • Publication number: 20120034707
    Abstract: Disclosed are atomically precise nanoribbons formed by gradient-driven catalytic etching of crystalline substrates to produce edges formed along specific crystallographic axes by thermally-activated particles. Also provided are related methods for fabrication of these nanoribbon structures. Further provided are devices and related methods for power generation and for detection of specific targets using the disclosed structures.
    Type: Application
    Filed: June 1, 2009
    Publication date: February 9, 2012
    Inventors: Sujit S. Datta, Douglas R. Strachan, Samuel M. Khamis, Alan T. Johnson, JR., Yaping Dan
  • Patent number: 7977054
    Abstract: Chemical field effect sensors comprising nanotube field effect devices having biopolymers such as single stranded DNA functionally adsorbed to the nanotubes are provided. Also included are arrays comprising the sensors and methods of using the devices to detect volatile compounds.
    Type: Grant
    Filed: March 29, 2006
    Date of Patent: July 12, 2011
    Assignees: The Trustees of the University of Pennsylvania, Monell Chemical Senses Center
    Inventors: Alan T. Johnson, Jr., Alan Gelperin, Cristian Staii
  • Publication number: 20100247381
    Abstract: Disclosed are copolymers of carbon nanotubes, as well as processes and applications of carbon nanotube dispersions. Carbon nanotube emulsions and related technology are also disclosed. The controlled deposition of carbon nanotubes on substrates is also provided. Methods of purifying single-walled carbon nanotubes are also provided. Devices made according to the disclosed methods are further described herein.
    Type: Application
    Filed: June 3, 2010
    Publication date: September 30, 2010
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Arjun G. Yodh, Mohammad F. Islam, Alan T. Johnson, JR., Danvers E. Johnston
  • Publication number: 20100144535
    Abstract: Disclosed are devices comprising multiple nanogaps having a separation of less than about 5 nm. Also disclosed are methods for fabricating these devices.
    Type: Application
    Filed: February 13, 2008
    Publication date: June 10, 2010
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: Douglas R. Strachan, Danvers E. Johnston, Beth S. Guiton, Peter K. Davies, Dawn A. Bonnell, Alan T. Johnson, JR.
  • Publication number: 20100088040
    Abstract: Chemical field effect sensors comprising nanotube field effect devices having biopolymers such as single stranded DNA or RNA functionally adsorbed to the nanotubes are provided. Also included are arrays comprising the sensors and methods of using the devices to detect volatile compounds.
    Type: Application
    Filed: July 13, 2007
    Publication date: April 8, 2010
    Applicant: The Trustees of the University of Pennsylvania
    Inventor: Alan T. Johnson, JR.
  • Patent number: 6897009
    Abstract: A shadow mask method to fabricate electrodes with nanometer scale separation utilizes nanotubes (NTs). Metal wires with gaps are made by incorporating multi-wall carbon nanotubes (MWNTs) or single-wall carbon nanotubes (SWNTs) (or bundles thereof) into a tri-layer electron beam lithography process. The simple, highly controllable, and scaleable method can be used to make gaps with widths between 1 and 100 nm. Electronic transport measurements performed on individual SWNTs bridge nanogaps smaller than 30 nm. Metallic SWNTs exhibit quantum dot behavior with an 80 meV charging energy and a 20 meV energy level splitting. Semiconducting SWNTs show an anomalous field effect transistor behavior.
    Type: Grant
    Filed: November 29, 2000
    Date of Patent: May 24, 2005
    Assignee: Trustees of the University of Pennsylvania
    Inventors: Alan T. Johnson, Jr., Marko Radosavljevic, Jacques Lefebvre
  • Publication number: 20030186167
    Abstract: A shadow mask method to fabricate electrodes with nanometer scale separation utilizes nanotubes (NTs). Metal wires with gaps are made by incorporating multi-wall carbon nanotubes (MWNTs) or single-wall carbon nanotubes (SWNTs) (or bundles thereof) into a tri-layer electron beam lithography process. The simple, highly controllable, and scaleable method can be used to make gaps with widths between 1 and 100 nm. Electronic transport measurements performed on individual SWNTs bridge nanogaps smaller than 30 nm. Metallic SWNTs exhibit quantum dot behavior with an 80 meV charging energy and a 20 meV energy level splitting. Semiconducting SWNTs show an anomalous field effect transistor behavior.
    Type: Application
    Filed: January 29, 2003
    Publication date: October 2, 2003
    Inventors: Alan T. Johnson Jr, Marko Radosavljevic, Jacques Lefebvre