Abstract: Methods and systems are disclosed related to determining whether there is a proper fit between a user interface and a face of a user. The methods and systems involve generating seal information associated with a seal region between a face of a user and a current user interface donned on the face of the user. The methods and systems are further related to analyzing the seal information to determine whether a leak exists in the seal region. If the leak exists, the systems and methods include analyzing the seal information to determine a location of the leak within the seal region. The systems and methods further include determining a new user interface to replace the current user interface based on the current user interface and the location of the leak.

Abstract: Touch sensor panel configurations for reducing wobble error for a stylus translating on a surface over and between electrodes of the touch sensor panel are disclosed. In some examples, electrodes with more linear signal profiles are correlated with lower wobble error. In some examples, diffusing elements formed of floating segments of conductive materials can diffuse signal from a stylus to a plurality of electrodes, thus, making the signal profiles associated with the electrodes more linear. In addition, diffusing elements can be configured to improve the optical uniformity of the touch sensor panel. In some examples, the diffusing elements can be formed on the same layer as floating dummy pixels and resemble a plurality of merged floating dummy pixels.

Abstract: The present invention relates to the engineering an animal model, preferably mammalian models, more preferably a rat model representing Charcot-Marie-Tooth disease 2A (CMT2A) harboring the p.Arg364Trp or p.His361Tyr Mfn2 mutation, whose human counterpart results in a severe, early-onset axonal neuropathy. A model having the p.Arg364Trp Mfn2 mutation is based on a mutation made using zinc finger endonuclease technology in fertilized rat eggs. Cohorts of mutants and wild type littermates were characterized behaviorally and shown to develop multiple motor deficits that worsened over time. Separate cohorts of mutant and wild type rats sacrificed at 7, 40, and 48 weeks and analyzed by light microscopy showed a reduced density of myelinated axons and active axonal degeneration in distal but not proximal nerves, as well as axonal degeneration in the fasciculus gracilis of the cervical spinal cord at 40 and 48 weeks.

Abstract: Improvements in distributed ledger technology for capturing, maintaining and updating data for asset-backed securitizations are described. The invention provides a distributed ledger platform which automates the capture of specified data regarding the underlying financial assets, including owners, trustees, servicers and other parties associated with asset-backed securitizations, and stores and maintains the data in a blockchain to provide users with a secure, reliable, immutable and distributed ledger of the data and to generate custom data reports of information stored in the ledger. An offchain database may be maintained in synchrony with the blockchain to allow for reduced computational load. The invention also provides a mechanism for managing changes in the data using a smart contract based consensus mechanism, for example, to record securitization party replacements in an automated manner.

Abstract: Aspects of the subject disclosure may include, for example, identifying unselected video content items and preconfiguring playback views for unselected video content items. During a warm-up phase, access to the unselected video content items is precoordinated individually with a separate video player, manifests and license/key are retrieved in anticipation for possible selection for playback. Subsequent selection of one of the unselected video content items initiates playback responsive to selection without repeating any of the preconfiguring, preauthorizing or fetching. Other embodiments are disclosed.

Abstract: Aspects of the subject disclosure may include, for example, identifying unselected video content items and preconfiguring playback views for unselected video content items. During a warm-up phase, access to the unselected video content items is precoordinated individually with a separate video player, manifests and license/key are retrieved in anticipation for possible selection for playback. Subsequent selection of one of the unselected video content items initiates playback responsive to selection without repeating any of the preconfiguring, preauthorizing or fetching. Other embodiments are disclosed.

Abstract: Aspects of the subject disclosure may include, for example, identifying unselected video content items and preconfiguring playback views for unselected video content items. During a warm-up phase, access to the unselected video content items is precoordinated individually with a separate video player, manifests and license/key are retrieved in anticipation for possible selection for playback. Subsequent selection of one of the unselected video content items initiates playback responsive to selection without repeating any of the preconfiguring, preauthorizing or fetching. Other embodiments are disclosed.

Abstract: A heat pipe includes a binary working fluid including a composition proximate to and less than or equal to the azeotropic point in a thermodynamic phase diagram as a function of the composition of the binary working fluid. Moreover, in a liquid phase of the binary working fluid, a boiling point of the binary working fluid as a function of temperature and the composition in the thermodynamic phase diagram is approximately constant. For example, the boiling point may vary by less than a degree Celsius over a range of compositions proximate to and less than or equal to the azeotropic point. Furthermore, components in the binary working fluid may be fully miscible as a function of the temperature and the composition in the thermodynamic phase diagram, a component in the binary working fluid may include a non-zero dipole moment, and/or the component may form a hydrogen bond with water.

Abstract: A compound of formula (I) or a pharmaceutically acceptable salt, hydrate or prodrug thereof for inhibiting Syk activity,

Abstract: A heat pipe includes a binary working fluid including a composition proximate to and less than or equal to the azeotropic point in a thermodynamic phase diagram as a function of the composition of the binary working fluid. Moreover, in a liquid phase of the binary working fluid, a boiling point of the binary working fluid as a function of temperature and the composition in the thermodynamic phase diagram is approximately constant. For example, the boiling point may vary by less than a degree Celsius over a range of compositions proximate to and less than or equal to the azeotropic point. Furthermore, components in the binary working fluid may be fully miscible as a function of the temperature and the composition in the thermodynamic phase diagram, a component in the binary working fluid may include a non-zero dipole moment, and/or the component may form a hydrogen bond with water.

Abstract: A heat pipe includes a binary working fluid including a composition proximate to and less than or equal to the azeotropic point in a thermodynamic phase diagram as a function of the composition of the binary working fluid. Moreover, in a liquid phase of the binary working fluid, a boiling point of the binary working fluid as a function of temperature and the composition in the thermodynamic phase diagram is approximately constant. For example, the boiling point may vary by less than a degree Celsius over a range of compositions proximate to and less than or equal to the azeotropic point. Furthermore, components in the binary working fluid may be fully miscible as a function of the temperature and the composition in the thermodynamic phase diagram, a component in the binary working fluid may include a non-zero dipole moment, and/or the component may form a hydrogen bond with water.

Abstract: A heat pipe includes a binary working fluid including a composition proximate to and less than or equal to the azeotropic point in a thermodynamic phase diagram as a function of the composition of the binary working fluid. Moreover, in a liquid phase of the binary working fluid, a boiling point of the binary working fluid as a function of temperature and the composition in the thermodynamic phase diagram is approximately constant. For example, the boiling point may vary by less than a degree Celsius over a range of compositions proximate to and less than or equal to the azeotropic point. Furthermore, components in the binary working fluid may be fully miscible as a function of the temperature and the composition in the thermodynamic phase diagram, a component in the binary working fluid may include a non-zero dipole moment, and/or the component may form a hydrogen bond with water.

Abstract: The present invention provides a compound, namely (+)-3?-Angeloyloxy-4?-keto-3?,4?-dihydroseselin (Pd-Ib) derived from Bupleurum malconense as the potential anti-inflammation drug. The present invention also relates to methods of preparing the compounds and using the same for treating inflammation.

Abstract: A compound of formula (I) or a pharmaceutically acceptable salt, hydrate or prodrug thereof for inhibiting Syk activity,

Abstract: The present invention provides a compound, namely (+)-3?-Angeloyloxy-4?-keto-3?, 4?-dihydroseselin (Pd-Ib) derived from Bupleurum malconense as the potential anti-inflammation drug. The present invention also relates to methods of preparing the compounds and using the same for treating inflammation.

Abstract: A system employs space-time coding characterized at the transmitter by bit-interleaved coded modulation (BICM) combined with multi-carrier Orthogonal Frequency Division Multiplexing (OFDM) modulation. Space-Time coding techniques improve transmission efficiency in radio channels by using multiple transmit and/or receive antennas and coordination of the signaling over these antennas. Bit-interleaved coded modulation provides good diversity gain with higher-order modulation schemes that employ binary convolutional codes. OFDM modulation allows for wideband transmission over frequency selective radio channels. A receiver demodulates the OFDM signal and applies multi-input, multi-output (MIMO) demapping to estimate the BICM encoded bitstream. After deinterleaving of the BICM encoded bitstream, maximum a posteriori (MAP) decoding is applied to the resulting bit stream to generate soft output values.

Abstract: The present invention provides bipyrimidinyl diphosphine compounds of the formula wherein R is optionally substituted alkyl, cycloalkyl, aryl or heteroaryl; R? and R? are independently optionally substituted alkyl, cycloalkyl, aryl or heteroaryl; or an enantiomer thereof; or an enantiomeric mixture thereof. The compounds of the formula (I) are chiral atropisomeric bipyrimidinyl diphosphine compounds and, thus, may be employed as ligands to generate chiral transition metal catalysts which may be applied in a variety of asymmetric reactions, e.g., in palladium catalyzed asymmetric allylic substitution reactions. The compounds of the present invention are easily accessible in high enantiomeric purity according to the methods disclosed herein.

Abstract: A system employs space-time coding characterized at the transmitter by bit-interleaved coded modulation (BICM) combined with modulating several streams of the BICM encoded data for transmission over two or more antennas. Space-time coding techniques improve transmission efficiency in radio channels by using multiple transmit and/or receive antennas and coordination of the signaling over these antennas. Bit-interleaved coded modulation provides good diversity gain with higher-order modulation schemes that employ binary convolutional codes. A receiver demodulates the received signals and applies multi-input, multi-output (MIMO) demapping to estimate the BICM encoded bitstream. After deinterleaving of the BICM encoded bitstream, maximum a posteriori (MAP) decoding is applied to the resulting bit stream to generate soft output values. By applying well-known turbo-decoding principles to iteratively demap and decode, the overall receiver performance is significantly improved.

Abstract: A composition and method for removing a filter cake from a horizontal wellbore in a subterranean formation using a composition containing a inorganic or organic acidic material, a cationic fluorocarbon surfactant, an alkyl alcohol, water optionally containing ammonium chloride and at least one of an alkyl polyglycoside and a betaine surfactant to produce a stable foam used to remove filter cake from a horizontal wellbore.