Abstract: A postural sway analysis system is disclosed. The system includes a camera worn by an individual, a processing unit coupled to the camera, a floor marker placed on a floor near the shoes or feet of the individual. The camera is configured to acquire images of the floor marker, which has a known size or diameter, while the individual is standing. The processing unit is configured to capture an initial calibration image of the floor marker using the camera while an individual is standing still to determine the distance between the camera and the floor marker. The processing unit is further configured to capture subsequent time-varying images of the floor marker while the individual is standing (and swaying). Furthermore, the processing unit is configured to compare the calibration images to the subsequent time-varying images to determine a postural sway of the individual.

Abstract: A breakaway connector generally includes a first valve having a first rotating-type fluid control member, and a second valve that is attachable to the first valve and has a second rotating-type fluid control member. Each of the fluid control members has an open position in which fluid is permitted to flow through the respective valve, and a closed position in which fluid is prevented from flowing through the respective valve. Each one of the valves is configured to engage the fluid control member of the other one of the valves to move the fluid control member from the open position to the closed position upon detachment of the valves from one another.

Abstract: The present invention relates to a system and methods generally aimed at surgery. More particularly, the present invention is directed at a system and related methods for performing surgical procedures and assessments involving the use of neurophysiology.

Abstract: A pedicle access system including a cannula, a stylet, and a removable T-handle. The pedicle access system may be used to percutaneously approach the pedicle, initiate pilot hole formation, and conduct a stimulation signal to the target site for the purposes of performing a pedicle integrity assessment during the pilot hole formation. To do this, the cannula and stylet are locked in combination and inserted through an operating corridor to the pedicle target site, using the T-handle to facilitate easy movement and positioning of the cannula/stylet combination. A stimulation signal may be applied during pilot hole formation to conduct the pedicle integrity assessment. In a significant aspect, the T-handle may be detached from the cannula/stylet combination to facilitate the use of various surgical tools as necessary.

Abstract: The present invention relates to therapeutic dosing regimens utilizing a dose reduction strategy for treating disorders characterized by marked elevations of low density protein cholesterol (LDL-C) in the plasma of a patient. The subject therapeutic dosing regimens involve delivering as a single administration or plurality of administrations of an anti-proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist antibody as an initial dose of at least about 100 mg, and delivering as a single administration or plurality of administrations at a subsequent dose in an amount that is about the same as the initial dose, or at least half the initial dose after the patient has a LDL-C level at or below about 25, 20, 15 or 10 mg/dL, preferably at or below 10 mg/dL.

Abstract: The present disclosure provides a method of treating a neurodegenerative disorder, the method comprising administering a DNA methyltransferase inhibitor.

Abstract: A breakaway connector generally includes a first valve having a first rotating-type fluid control member, and a second valve that is attachable to the first valve and has a second rotating-type fluid control member. Each of the fluid control members has an open position in which fluid is permitted to flow through the respective valve, and a closed position in which fluid is prevented from flowing through the respective valve. Each one of the valves is configured to engage the fluid control member of the other one of the valves to move the fluid control member from the open position to the closed position upon detachment of the valves from one another.

Abstract: A method for acquiring gait parameters of an individual is disclosed. The method includes capturing calibration images from foot marker placed on feet or shoes of an individual while an individual is standing still, the calibration images are obtained from a camera worn by the individual, capturing subsequent time-varying images from the foot markers while the individual is walking, and comparing the calibration images to the subsequent time-varying images by a processing unit that is coupled to the camera to determine changes between the initial relative image size of the foot markers and the time-varying images of the foot markers as a function of time to analyze gait of the individual.

Abstract: A method of preventing soil erosion in, among areas, seaside locations, includes drilling holes in the ground and filling the holes with a mixture of the soil and gelatin, and then curing the mixture in situ to form a barrier against soil erosion.

Abstract: A pedicle access system including a cannula, a stylet, and a removable T-handle. The pedicle access system may be used to percutaneously approach the pedicle, initiate pilot hole formation, and conduct a stimulation signal to the target site for the purposes of performing a pedicle integrity assessment during the pilot hole formation. To do this, the cannula and stylet are locked in combination and inserted through an operating corridor to the pedicle target site, using the T-handle to facilitate easy movement and positioning of the cannula/stylet combination. A stimulation signal may be applied during pilot hole formation to conduct the pedicle integrity assessment. In a significant aspect, the T-handle may be detached from the cannula/stylet combination to facilitate the use of various surgical tools as necessary.

Abstract: A method for acquiring gait parameters of an individual is disclosed. The method includes capturing calibration images from foot marker placed on feet or shoes of an individual while an individual is standing still, the calibration images are obtained from a camera worn by the individual, capturing subsequent time-varying images from the foot markers while the individual is walking, and comparing the calibration images to the subsequent time-varying images by a processing unit that is coupled to the camera to determine changes between the initial relative image size of the foot markers and the time-varying images of the foot markers as a function of time to analyze gait of the individual.

Abstract: The present invention relates to therapeutic dosing regimens utilizing a dose reduction strategy for treating disorders characterized by marked elevations of low density protein cholesterol (LDL-C) in the plasma of a patient. The subject therapeutic dosing regimens involve delivering as a single administration or plurality of administrations of an anti-proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist antibody as an initial dose of at least about 100 mg, and delivering as a single administration or plurality of administrations at a subsequent dose in an amount that is about the same as the initial dose, or at least half the initial dose after the patient has a LDL-C level at or below about 25, 20, 15 or 10 mg/dL, preferably at or below 10 mg/dL.

Abstract: An electronic interactive airline-shipped-cargo handling and management system and method therefor comprising a least one IATA airline-cargo-information data extraction engine, at least one data base, at least one user portal for access by at least one stakeholder to manage, track, or reconcile an airline-cargo shipment, at least one mobile warehouse portal, at least one airline-shipped-cargo handling server having at least one messaging engine, at least one mobile warehouse management system and a network connecting all of the foregoing for the access and management of airline-cargo-information data extracted from at least one airline's IATA messages by said IATA airline-cargo-information data extraction engine, and the transmission of said extracted airline-cargo-information data to and from said at least one user portal and said at least one mobile warehouse portal respectively, in real time, while the shipped airline-cargo is being processed through a cargo handling logistics' chain.

Abstract: A method of preventing soil erosion in, among areas, seaside locations, includes drilling holes in the ground and filling the holes with a mixture of the soil and gelatin, and then curing the mixture in situ to form a barrier against soil erosion.

Abstract: An implantable pressure sensor arrangement is disclosed. The sensor arrangement includes a pressure sensor, a cable having a plurality of conductors coupled to the pressure sensor, a flexible balloon partially fitted around the subassembly, thereby encasing the pressure sensor while each end of the cable is extending away from the balloon, the flexible balloon is then filled with an incompressible fluid, thereby allowing pressure changes outside of the balloon to be sensed by the pressure sensor inside of the balloon.

Abstract: The present application includes a position tracking system for tracking the location of surgical objects within the surgical field, a neuromonitoring system for detecting the existence of (and optionally the distance and/or direction to) neural structures during a surgical procedure, and a processing system communicatively linked to both the position tracking system and the neuromonitoring system.