Abstract: An adjustable watch clasp and a method of using thereof are disclosed. The adjustable watch clasp may have a first clasp section and a second clasp section. The first clasp section may be part of a suspension system that actively adjusts the spacing between the first clasp section and an adjacent watch band link to provide needed spacing when a user is wearing a watch band with the adjustable watch clasp. The active adjustment may be needed for when the user wearing the watch band jerks or accelerates his or her wrist and the first clasp section and the adjacent link need to expand away from each other to create spacing for the tightness of the watch band to not bother the user. The second clasp section may have a micro-adjuster mechanism that allows the user to manually adjust the tightness of the watch band having the second clasp section.

Abstract: An analytics computing device is provided. The analytics computing device includes a processor in communication with a database. The database configured to store electronic health record (EHR) data including structured EHR data and unstructured EHR data for a patient. The processor is configured to retrieve the EHR data from the database. The processor is further configured to parse, using a natural language processing model, the unstructured EHR data to retrieve one or more indicator phrases, the one or more indicator phrases correlated to an Alzheimer's disease (AD) diagnosis. The processor is further configured to identify, using a predictive model, the patient as being at risk for AD based on the retrieved indicator phrases and on the structured EHR data.

Abstract: A method, apparatus and computer program product are provided in order to utilize task value units for imaging interpretation and other tasks, such as in the assignment of imaging interpretation and other tasks to a plurality of users. In the context of a method, the method associates, for each of a plurality of different types of imaging interpretation tasks and for each of a plurality of other tasks, a first task value unit therewith. The method also associates, for at least some of the plurality of different types of imaging interpretation or other tasks, a second task value unit, different than the first task value unit, therewith. Further, the method assigns imaging interpretation and other tasks to a plurality of users based at least partially upon the first and second task value units associated with the respective imaging interpretation tasks and the other tasks.

Abstract: A method, apparatus and computer program product are provided in order to utilize task value units for imaging interpretation and other tasks, such as in the assignment of imaging interpretation and other tasks to a plurality of users. In the context of a method, the method associates, for each of a plurality of different types of imaging interpretation tasks and for each of a plurality of other tasks, a first task value unit therewith. The method also associates, for at least some of the plurality of different types of imaging interpretation or other tasks, a second task value unit, different than the first task value unit, therewith. Further, the method assigns imaging interpretation and other tasks to a plurality of users based at least partially upon the first and second task value units associated with the respective imaging interpretation tasks and the other tasks.

Abstract: Disclosed herein are methods for detecting the presence of an isocitrate dehydrogenase mutation in a sample from a subject. Also disclosed are methods diagnosing and treating subjects having a cancer including determining whether the cancer may likely be treated with one or more retinoids.

Abstract: The present invention relates to novel sequences for use in detection, diagnosis and treatment of diseases, including cancer. The invention provides novel splice products of human DKKL-1 gene. The present invention provides methods of using polynucleotides having the novel splice products of the human DKKL-1 sequences, their corresponding gene products and modulators of the DKKL-1 splice products for the detection, diagnosis, prevention and/or treatment of associated cancers.

Abstract: This invention is in the field of cancer-related genes. Specifically it relates to methods for detecting cancer or the likelihood of developing cancer based on the presence or absence of the SEM A4D gene or proteins encoded by this gene. The invention also provides methods and molecules for upregulating or downregulating the SEMA4D gene.

Abstract: This invention is in the field of cancer-related genes. Specifically it relates to methods for detecting cancer or the likelihood of developing cancer based on the presence or absence of the tm-PTP? gene or proteins encoded by this gene. The invention also provides methods and molecules for upregulating or downregulating the tm-PTP? gene.

Abstract: This invention is in the field of cancer-related genes. Specifically it relates to methods for detecting cancer or the likelihood of developing cancer based on the presence or absence of the ADAM10 gene or proteins encoded by this gene. The invention also provides methods and molecules for upregulating or downregulating the ADAM10 gene.

Abstract: The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.

Abstract: The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.

Abstract: The present invention relates to novel sequences for use in detection, diagnosis and treatment of diseases, including cancer. The invention provides novel splice products of human DKKL-1 gene. The present invention provides methods of using polynucleotides having the novel splice products of the human DKKL-1 sequences, their corresponding gene products and modulators of the DKKL-1 splice products for the detection, diagnosis, prevention and/or treatment of associated cancers.

Abstract: This invention is in the field of cancer-related genes. Specifically it relates to methods for detecting cancer or the likelihood of developing cancer based on the presence or absence of the SEM A4D gene or proteins encoded by this gene. The invention also provides methods and molecules for upregulating or downregulating the SEMA4D gene.

Abstract: The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.

Abstract: The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.

Abstract: This invention is in the field of cancer-associated (CA) genes. Specifically it relates to methods for detecting and diagnosing cancer or the likelihood of developing cancer based on the presence or absence of expression of certain genes or proteins encoded by those genes. The invention also provides methods and molecules for upregulating or downregulating these cancer-associated genes.

Abstract: Disclosed herein are methods and compositions for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.

Abstract: The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.

Abstract: The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.

Abstract: The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.