Patents by Inventor Albert Lai

Albert Lai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel therapeutic targets in cancer
    Publication number: 20080299561
    Abstract: The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
    Type: Application
    Filed: December 21, 2007
    Publication date: December 4, 2008
    Inventors: David W. Morris, Marc S. Malandro, Albert Lai, Christin Tse, Ali Fattaey
  • Therapeutic targets in cancer
    Patent number: 7332281
    Abstract: The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
    Type: Grant
    Filed: April 27, 2004
    Date of Patent: February 19, 2008
    Assignee: Sagres Discovery, Inc.
    Inventors: David W. Morris, Marc S. Malandro, Albert Lai, Christin Tse, Ali Fattaey
  • Novel compositions and methods in cancer
    Publication number: 20070237770
    Abstract: This invention is in the field of cancer-associated (CA) genes. Specifically it relates to methods for detecting and diagnosing cancer or the likelihood of developing cancer based on the presence or absence of expression of certain genes or proteins encoded by those genes. The invention also provides methods and molecules for upregulating or downregulating these cancer-associated genes.
    Type: Application
    Filed: April 12, 2006
    Publication date: October 11, 2007
    Inventors: Albert Lai, Abdallah Fanidi, Robert Booher, Guoying Yu, Edward Moler, Michael Rowe
  • Modulation of endogenous gene expression in cells
    Patent number: 7220719
    Abstract: Disclosed herein are methods and compositions for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
    Type: Grant
    Filed: May 13, 2004
    Date of Patent: May 22, 2007
    Assignee: Sangamo Biosciences, Inc.
    Inventors: Casey C. Case, Elizabeth Wolffe, legal representative, Fyodor Urnov, Albert Lai, Andrew Snowden, Siyuan Tan, Philip Gregory, Alan Wolffe, deceased
  • Novel compositions and methods in cancer
    Publication number: 20070042385
    Abstract: The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
    Type: Application
    Filed: February 23, 2005
    Publication date: February 22, 2007
    Inventors: David Morris, Marc Malandro, Albert Lai, Christin Tse, Ali Fattaey
  • Novel therapeutic targets in cancer
    Publication number: 20060194210
    Abstract: The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
    Type: Application
    Filed: April 27, 2004
    Publication date: August 31, 2006
    Inventors: David Morris, Marc Malandro, Albert Lai, Christin Tse, Ali Fattaey
  • Novel therapeutic targets in cancer
    Publication number: 20060024677
    Abstract: The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
    Type: Application
    Filed: July 20, 2004
    Publication date: February 2, 2006
    Inventors: David Morris, Marc Malandro, Albert Lai, Christin Tse, Ali Fattaey
  • Modulation of endogenous gene expression in cells
    Patent number: 6933113
    Abstract: Disclosed herein are methods and compositions for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
    Type: Grant
    Filed: August 28, 2001
    Date of Patent: August 23, 2005
    Assignee: Sangamo BioSciences, Inc.
    Inventors: Casey C. Case, Elizabeth Wolffe, Fyodor Urnov, Albert Lai, Andrew Snowden, Siyuan Tan, Philip Gregory, Alan Wolffe
  • Modulation of gene expression using localization domains
    Patent number: 6919204
    Abstract: Methods and compositions for regulating gene expression are provided. In particular, methods and compositions comprising localization domains, and fusions of localization domains with DNA binding domains and, optionally regulatory domains, are provided.
    Type: Grant
    Filed: September 28, 2001
    Date of Patent: July 19, 2005
    Assignee: Sangamo Biosciences, Inc.
    Inventors: Elizabeth J. Wolffe, Fyodor Urnov, Albert Lai, Eva Raschke, Alan P. Wolffe
  • Modulation of gene expression using localization domains
    Publication number: 20050130267
    Abstract: Methods and compositions for regulating gene expression are provided. In particular, methods and compositions comprising localization domains, and fusions of localization domains with DNA binding domains and, optionally regulatory domains, are provided.
    Type: Application
    Filed: January 28, 2005
    Publication date: June 16, 2005
    Inventors: Alan Wolffe, Fyodor Urnov, Albert Lai, Eva Raschke
  • Modulation of endogenous gene expression in cells
    Publication number: 20040204345
    Abstract: Disclosed herein are methods and compositions for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
    Type: Application
    Filed: May 13, 2004
    Publication date: October 14, 2004
    Applicant: Sangamo Biosciences, Inc.
    Inventors: Casey C. Case, Alan Wolffe, Elizabeth J. Wolffe, Fyodor Urnov, Albert Lai, Andrew Snowden, Siyuan Tan, Philip Gregory
  • Modulation of gene expression using localization domains
    Publication number: 20030082552
    Abstract: Methods and compositions for regulating gene expression are provided. In particular, methods and compositions comprising localization domains, and fusions of localization domains with DNA binding domains and, optionally regulatory domains, are provided.
    Type: Application
    Filed: September 28, 2001
    Publication date: May 1, 2003
    Inventors: Alan P. Wolffe, Fyodor Urnov, Albert Lai, Eva Raschke, Elizabeth J. Wolffe
  • Modulation of endogenous gene expression in cells
    Publication number: 20020160940
    Abstract: Disclosed herein are methods and compositions for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
    Type: Application
    Filed: August 28, 2001
    Publication date: October 31, 2002
    Inventors: Casey C. Case, Alan Wolffe, Fyodor Urnov, Albert Lai, Andrew Snowden, Siyuan Tan, Philip Gregory