Abstract: Described are a system and method for maintaining confidential records of an individual over a publicly accessible network. The system and method provide adequate confidentiality of the confidential records, mobility of individual access to the records, security of the data in the records, individual control of the confidential records, and integration with institutional information systems. The individual selects a publicly accessible record server for storing a confidential record. The confidential record is encrypted and stored by the gateway system on the selected record server. A predetermined agent is given an access token for accessing the confidential record over the network through the gateway server system. In a medical context, for example, the predetermined agent can be a health care institution, a medical research facility, or the individual who is a patient. The individual determines the privileges for the predetermined agent for accessing the confidential records.

Abstract: The invention provides purified ARAg polypeptides, antibodies against ARAg polypeptides and nucleic acids encoding ARAg polypeptides. Also provided are methods of diagnosis and treatment using the same. ARAg polypeptides are typically present on the surface of alloantigen-activated CD8.sup.+ T-cells, monocytes, granulocytes and peripheral dendritic cells, and substantially absent on resting T-cells, mitogen-activated CD8.sup.+ T-cells, B-cells, erythroid cell lines, myelomonocitic cell lines, EBV-LCL cell lines and fibroblastoid cell lines. An exemplary ARAg polypeptide, termed ARAg-h-1, has a signal sequence, seven variable-type immunoglobulin-like domains, a transmembrane domain and an intracellular domain.