Abstract: A method for adjusting a system autonomy level of a cargo handling system configured for autonomous control by a processor is disclosed. In various embodiments, the method includes receiving by the processor a sensor database from a plurality of sensing agents in operable communication with the processor; determining by the processor a confidence level based on the sensor database; and adjusting by the processor the system autonomy level for continued operation of the cargo handling system.

Abstract: A cargo handling system configured for autonomous control is disclosed, including, for example a plurality of power drive units, the plurality of power drive units configured to convey a plurality of objects over a conveyance surface; a plurality of sensing agents, the plurality of sensing agents configured to transmit a run-time database from the plurality of sensing agents, the run-time database including data from which a positioning of the plurality of objects on the cargo handling system may be determined; and a distributed control system in operable communication with the plurality of sensing agents and the plurality of power drive units, the distributed control system including a supervisory control processor configured to provide an estimate of a current state of the plurality of objects and an actuator control processor configured to control the plurality of power drive units based on the current state of the plurality of objects.

Abstract: A method for performing a safety assessment of a cargo handling system controlled by a processor and having a plurality of sensing agents is disclosed. In various embodiments, the method includes receiving by the processor a run-time database from the plurality of sensing agents, the run-time database including data from which a positioning of a plurality of objects on the cargo handling system may be determined; generating by the processor a mapping of the positioning of the plurality of objects; validating by the processor whether a run-time state of the cargo handling system is in violation of a safety protocol; and determining by the processor whether to implement a corrective action.

Abstract: A method for self-assessing components of a cargo handling system configured for autonomous control by a processor is disclosed. In various embodiments, the method includes receiving by the processor a sensor database from a plurality of sensing agents in operable communication with the processor; testing by the processor the plurality of sensing agents by comparing the sensor database against a sensor assessment; and performing by the processor a first calibration assessment of the plurality of sensing agents to assess whether a compromised operational status of the cargo handling system has occurred due to a failure of one or more of the plurality of sensing agents.

Abstract: The present invention discloses methods of quantitative multiplex amplicon sequencing system for labeling the original DNA sample with an oligonucleotide barcode sequence by polymerase chain reaction, amplifying the genomic region(s) for high-throughput sequencing and quantifying the sequence in DNA sample. The methods allow analyzing a DNA sample comprising between 1 and 10,000 Target Regions for quantifying potential sequence variants and wildtype molecules.

Abstract: The present disclosure provides an end-to-end cargo handling system. The end-to-end cargo handling system comprises a transportation unit comprising a first sensing agent, a lift unit comprising a second sensing agent, and a control module in communication with the transportation unit and the lift unit via a network, wherein the transportation unit and the lift unit are configured to move a cargo unit from a first location to a second location autonomously.

Abstract: The present disclosure provides an end-to-end cargo handling system. The end-to-end cargo handling system comprises a transportation unit comprising a first sensing agent, a lift unit comprising a second sensing agent, and a control module in communication with the transportation unit and the lift unit via a network, wherein the transportation unit and the lift unit are configured to move a cargo unit from a first location to a second location autonomously.

Abstract: The present disclosure provides an end-to-end cargo handling system. The end-to-end cargo handling system comprises a transportation unit comprising a first sensing agent, a lift unit comprising a second sensing agent, and a control module in communication with the transportation unit and the lift unit via a network, wherein the transportation unit and the lift unit are configured to move a cargo unit from a first location to a second location autonomously.

Abstract: This disclosure describes a method of purifying several full-length oligonucleotide targets from corresponding synthesis truncation products, in a way that ensures roughly stoichiometric equality among the targets.

Abstract: An autonomous cargo handling system having a sensor self-calibration system may comprise a sensing agent configured to monitor a sensing zone, and a system controller in electronic communication with the first sensing agent. The system controller may be configured to receive structural cargo deck data from the first sensing agent, generate a real-time cargo deck model, identify a cargo deck component in the real-time cargo deck model, and determine a position of the sensing agent relative to the cargo deck component.

Abstract: A communication network configured for connection with a cargo handling system and a third party is disclosed. In various embodiments, the communication network includes a first processor; a first communication link connecting the first processor to the cargo handling system, the cargo handling system including a plurality of sensing agents configured to monitor a status of a cargo load; and a second communication link connecting the first processor to the third party, where the first processor is configured to receive a first load status data from the cargo handling system over the first communication link and to transmit a second load status data to the third party over the second communication link.

Abstract: A tracking system for communicating real-time information concerning a cargo load on a cargo handling system to a third party is disclosed. In various embodiments, the system includes a processor; a first communication link connecting the processor to the cargo handling system, the cargo handling system including a plurality of sensing agents configured to monitor a status of the cargo load; and a second communication link connecting the processor to the third party, where the processor is configured to receive a first load status data from the cargo handling system over the first communication link and to transmit a second load status data to the third party over the second communication link.

Abstract: A method for adjusting a system autonomy level of a cargo handling system configured for autonomous control by a processor is disclosed. In various embodiments, the method includes receiving by the processor a sensor database from a plurality of sensing agents in operable communication with the processor; determining by the processor a confidence level based on the sensor database; and adjusting by the processor the system autonomy level for continued operation of the cargo handling system.

Abstract: A cargo handling system configured for autonomous control is disclosed, including, for example a plurality of power drive units, the plurality of power drive units configured to convey a plurality of objects over a conveyance surface; a plurality of sensing agents, the plurality of sensing agents configured to transmit a run-time database from the plurality of sensing agents, the run-time database including data from which a positioning of the plurality of objects on the cargo handling system may be determined; and a distributed control system in operable communication with the plurality of sensing agents and the plurality of power drive units, the distributed control system including a supervisory control processor configured to provide an estimate of a current state of the plurality of objects and an actuator control processor configured to control the plurality of power drive units based on the current state of the plurality of objects.

Abstract: A method for self-assessing components of a cargo handling system configured for autonomous control by a processor is disclosed. In various embodiments, the method includes receiving by the processor a sensor database from a plurality of sensing agents in operable communication with the processor; testing by the processor the plurality of sensing agents by comparing the sensor database against a sensor assessment; and performing by the processor a first calibration assessment of the plurality of sensing agents to assess whether a compromised operational status of the cargo handling system has occurred due to a failure of one or more of the plurality of sensing agents.

Abstract: A method for performing a safety assessment of a cargo handling system controlled by a processor and having a plurality of sensing agents is disclosed. In various embodiments, the method includes receiving by the processor a run-time database from the plurality of sensing agents, the run-time database including data from which a positioning of a plurality of objects on the cargo handling system may be determined; generating by the processor a mapping of the positioning of the plurality of objects; validating by the processor whether a run-time state of the cargo handling system is in violation of a safety protocol; and determining by the processor whether to implement a corrective action.

Abstract: The present disclosure provides an end-to-end cargo handling system. The end-to-end cargo handling system comprises a transportation unit comprising a first sensing agent, a lift unit comprising a second sensing agent, and a control module in communication with the transportation unit and the lift unit via a network, wherein the transportation unit and the lift unit are configured to move a cargo unit from a first location to a second location autonomously.

Abstract: Provided herein are methods for encoding information in DNA molecules in a way that allows rapid and permanent erasure of information. As such, methods of erasing such information are also provided. Also provided are compositions that so encode information.

Abstract: The present disclosure provides an end-to-end cargo handling system. The end-to-end cargo handling system comprises a transportation unit comprising a first sensing agent, a lift unit comprising a second sensing agent, and a control module in communication with the transportation unit and the lift unit via a network, wherein the transportation unit and the lift unit are configured to move a cargo unit from a first location to a second location autonomously.

Abstract: A system for estimating mass of a ULD while on-board a vessel includes a system controller energizing one or more PDUs in communication with a conveyance surface of the vessel, the PDUs applying first and second forces to the ULD and transmitting first and second force parameters to a system integrator, one or more sensors measuring first and second accelerations of the ULD when the ULD moves into one or more sensing zones as a result of the forces and transmits first and second acceleration parameters to the system integrator, and the system integrator, which receives the first and second force parameters, and the first and second acceleration parameters, and calculates the mass of the ULD while the ULD is on-board the vessel by performing regression analysis on ordered pairs including the first force parameter and the first acceleration parameter, and the second force parameter and the second acceleration parameter.