Patents by Inventor Alex Brown
Alex Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250044842Abstract: Display assemblies for preventing delamination of an optical stack are disclosed. A continuous, interconnected airflow pathway includes each of a first, second, and third airflow passageways, where the first airflow passageway is located, at least in part, forward of the optical stack, the second airflow passageway is located, at least in part, rearward of the optical stack, and the third airflow passageway is located, at least in part, rearward of the second airflow passageway. One or more fan units are positioned along the continuous, interconnected airflow pathway, and when activated, push gas through the continuous, interconnected airflow pathway, including into the first and second airflow passageways to generate compressive forces by the gas at the optical stack.Type: ApplicationFiled: October 18, 2024Publication date: February 6, 2025Inventors: William Dunn, Mike Brown, Alex Moreau
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Patent number: 12207762Abstract: A cooking system positionable on a support surface includes a housing having an internal cooking compartment and an opening formed in the housing for accessing said internal cooking compartment. At least one heating element is provided for heating said internal cooking compartment. The heating element is operable to heat the internal cooking compartment while the opening is at least partially exposed to an ambient environment to allow fluid transfer between the ambient environment and the internal cooking compartment. An output from said at least one heating element is variable across said internal cooking compartment during operation of the system.Type: GrantFiled: September 16, 2022Date of Patent: January 28, 2025Assignee: SharkNinja Operating LLCInventors: Niall Christopher Denham, Georgia Banton, Gregory Fish, Alex Gushulak, Edward Brown, Ethan S. Kramer, Roger Neil Jackson, Andrew John Roy Tattersfield
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Patent number: 12209090Abstract: The present invention relates to a compound of formula (I), or one of its pharmaceutically acceptable salts: (I) wherein R1, R2 and —X—Y— have specific definitions. It also relates to the use of such a compound in therapy; and to a process for preparing it.Type: GrantFiled: February 14, 2020Date of Patent: January 28, 2025Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE STRASBOURG, ETAT FRANCAIS (MINISTÈRE DES ARMÉES), REPRESENTE PAR LA DIRECTION CENTRALE DU SERVICE DE SANTÉ DES ARMEESInventors: Rachid Baati, Richard Brown, José Dias, Alex Maryan-Instone, Jagadeesh Yerri
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Publication number: 20250031318Abstract: A method of manufacturing a via-in-via vertical interconnect in a printed circuit board (PCB), including: drilling a first hole through the PCB; drilling a second hole into a top side of the PCB; plating the first hole and the second hole with a conductive material to form an outer layer; drilling a third hole through the PCB wherein a portion of the plating is removed between the first hole and the second hole; filling the first, second, and third holes with an outer filler; drilling a fourth hole through the outer filler; plating the fourth hole with a conductive material to form an inner layer; filling the fourth hole with an inner filler; forming a via-in-via pad on top of the inner filler connected to the inner layer; and drilling a fifth hole through the bottom of the PCB along the fourth hole to remove a portion of the inner filler and inner layer wherein the top of the fifth hole is below the internal layer.Type: ApplicationFiled: July 19, 2023Publication date: January 23, 2025Inventors: Paul Brown, Alex Chan
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Patent number: 12206922Abstract: A video monitoring system can include multiple collectors to receive video beacon data from multiple video monitoring interface modules. At least one beacon stream is connected to receive data from multiple collectors. A processing module receives the beacon stream and provides a real-time event stream used for real-time data analysis and a video view stream used for long-term data analysis.Type: GrantFiled: February 8, 2024Date of Patent: January 21, 2025Assignee: Mux, Inc.Inventors: Adam Brown, Jonathan Dahl, Steven Heffernan, Justin Sanford, Matthew Ward, Scott Kidder, Benjamin Dodson, Alex Diehl
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Publication number: 20240274286Abstract: A method includes receiving a clinical data table for a patient. The clinical data table stores clinical data associated with the patient in tabular form. The method also includes extracting, from the clinical data table, one or more categorical features and one or more continuous features, and determining, using a clinical prediction model, one or more predicted clinical outcomes for the patient based on the one or more categorical features and the one or more continuous features extracted from the clinical data table. The method also includes providing, for output from a client device associated with a user, the one or more predicted clinical outcomes for the patient.Type: ApplicationFiled: February 9, 2023Publication date: August 15, 2024Applicant: Bristol-Myers Squibb CompanyInventors: Zekai Chen, Kevin Alex Brown
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Publication number: 20230410483Abstract: A method includes obtaining a first training data set including unannotated multi-dimensional medical images and executing a self-supervised masked image modeling (MIM) training process to pre-train an image encoder on the first training data set. The method also includes obtaining a second training data set that includes annotated multi-dimensional medical images. Here, each annotated multi-dimensional medical image includes a plurality of image voxels each paired with a corresponding ground-truth label indicating a class the corresponding image voxel belongs to. The method also includes executing a supervised training process to train an image analysis model on the second training data set to teach the image analysis model to learn how to predict the corresponding ground-truth labels for the plurality of image voxels of each annotated multi-dimensional medical image. The image analysis model incorporates the pre-trained image encoder.Type: ApplicationFiled: April 20, 2023Publication date: December 21, 2023Applicant: Bristol-Myers Squibb CompanyInventors: Zekai Chen, Kevin Alex Brown
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Patent number: 11718686Abstract: The invention provides antibodies and antigen-binding fragments thereof that selectively bind to an epitope within the core region of transglutaminase type 2 (TG2). Novel epitopes within the TG2 core are provided. The invention provides human TG2 inhibitory antibodies and uses thereof, particularly in medicine, for example in the treatment and/or diagnosis of conditions including Celiac disease, scarring, fibrosis-related diseases, neurodegenerative/neurological diseases and cancer.Type: GrantFiled: December 14, 2020Date of Patent: August 8, 2023Assignee: LIFEARCInventors: Tim Johnson, Phil Watson, David Matthews, Alex Brown
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Publication number: 20230203140Abstract: The present invention relates to humanised antibodies that bind amyloid peptides, which antibodies comprise mutations in the heavy chain and/or light chain variable domains, which mutations improve the binding activity. The antibodies may be useful in the treatment of Alzheimer's disease (AD).Type: ApplicationFiled: October 2, 2019Publication date: June 29, 2023Applicants: GEORG-AUGUST-UNIVERSITÄT GÖTTINGEN STIFTUNG ÖFFENTLICHEN RECHTS, UNIVERSITÄTSMEDIZIN, LIFEARCInventors: Thomas BAYER, Preeti BAKRANIA, Sarah DAVIES, Alex BROWN, Chido MPAMHANGA, David MATTHEWS, Mark CARR, Gareth HALL
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Publication number: 20210347867Abstract: The present invention relates to humanised antibodies that bind amyloid peptides, which antibodies comprise mutations in the heavy chain and/or light chain variable domains, which mutations improve the binding activity. The antibodies may be useful in the treatment of Alzheimer's disease (AD).Type: ApplicationFiled: October 2, 2019Publication date: November 11, 2021Applicants: GEORG-AUGUST-UNIVERSITÄT GÖTTINGEN STIFTUNG ÖFFENTLICHEN RECHTS, UNIVERSITÄTSMEDIZIN, LIFEARCInventors: Thomas BAYER, Preeti BAKRANIA, Sarah DAVIES, Alex BROWN, Chido MPAMHANGA, David MATTHEWS, Mark CARR, Gareth HALL
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Publication number: 20210101999Abstract: The invention provides antibodies and antigen-binding fragments thereof that selectively bind to an epitope within the core region of transglutaminase type 2 (TG2). Novel epitopes within the TG2 core are provided. The invention provides human TG2 inhibitory antibodies and uses thereof, particularly in medicine, for example in the treatment and/or diagnosis of conditions including Celiac disease, scarring, fibrosis-related diseases, neurodegenerative/neurological diseases and cancer.Type: ApplicationFiled: December 14, 2020Publication date: April 8, 2021Inventors: Tim Johnson, Phil Watson, David Matthews, Alex Brown
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Patent number: 10961319Abstract: The invention provides antibodies and antigen-binding fragments thereof that selectively bind to an epitope within the core region of transglutaminase type 2 (TG2). Novel epitopes within the TG2 core are provided. The invention provides human TG2 inhibitory antibodies and uses thereof, particularly in medicine, for example in the treatment and/or diagnosis of conditions including Celiac disease, scarring, fibrosis-related diseases, neurodegenerative/neurological diseases and cancer.Type: GrantFiled: May 23, 2018Date of Patent: March 30, 2021Assignee: LIFEARCInventors: Tim Johnson, Phil Watson, David Matthews, Alex Brown
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Patent number: 10912876Abstract: A system for controlling the position of a diaphragm in a diaphragm-containing pressure pod, is provided. The system can include a peristaltic pump, a pressure pod having a flow-through fluid side and a gas side that are separated by a diaphragm, and a pressure sensor operatively connected to the gas side. The pressure sensor is configured to sense pulses of pressure resulting from movement of the diaphragm and caused by the action of the peristaltic pump. A gas source and a valve can be in fluid communication with the gas side of the pressure pod and can be configured to provide gas to, or vent gas from, the gas side. A controller receives pressure signals from the pressure sensor and controls the valve in response, and in so doing, controls the position of the diaphragm. Methods for positioning the diaphragm are also included.Type: GrantFiled: July 8, 2019Date of Patent: February 9, 2021Assignee: Fresenius Medical Care Holdings, Inc.Inventors: Martin Crnkovich, Lee Tanenbaum, Michael Emmanuel Kotsos, Fei Wang, Alex Brown
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Publication number: 20190336673Abstract: A system for controlling the position of a diaphragm in a diaphragm-containing pressure pod, is provided. The system can include a peristaltic pump, a pressure pod having a flow-through fluid side and a gas side that are separated by a diaphragm, and a pressure sensor operatively connected to the gas side. The pressure sensor is configured to sense pulses of pressure resulting from movement of the diaphragm and caused by the action of the peristaltic pump. A gas source and a valve can be in fluid communication with the gas side of the pressure pod and can be configured to provide gas to, or vent gas from, the gas side. A controller receives pressure signals from the pressure sensor and controls the valve in response, and in so doing, controls the position of the diaphragm. Methods for positioning the diaphragm are also included.Type: ApplicationFiled: July 8, 2019Publication date: November 7, 2019Inventors: Martin CRNKOVICH, Lee TANENBAUM, Michael Emmanuel KOTSOS, Fei WANG, Alex BROWN
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Patent number: 10441704Abstract: A system for controlling the position of a diaphragm in a diaphragm-containing pressure pod, is provided. The system can include a peristaltic pump, a pressure pod having a flow-through fluid side and a gas side that are separated by a diaphragm, and a pressure sensor operatively connected to the gas side. The pressure sensor is configured to sense pulses of pressure resulting from movement of the diaphragm and caused by the action of the peristaltic pump. A gas source and a valve can be in fluid communication with the gas side of the pressure pod and can be configured to provide gas to, or vent gas from, the gas side. A controller receives pressure signals from the pressure sensor and controls the valve in response, and in so doing, controls the position of the diaphragm. Methods for positioning the diaphragm are also included.Type: GrantFiled: December 5, 2017Date of Patent: October 15, 2019Assignee: Fresenius Medical Care Holdings, Inc.Inventors: Martin Crnkovich, Lee Tanenbaum, Michael Emmanuel Kotsos, Fei Wang, Alex Brown
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Publication number: 20180355060Abstract: The invention provides antibodies and antigen-binding fragments thereof that selectively bind to an epitope within the core region of transglutaminase type 2 (TG2). Novel epitopes within the TG2 core are provided. The invention provides human TG2 inhibitory antibodies and uses thereof, particularly in medicine, for example in the treatment and/or diagnosis of conditions including Celiac disease, scarring, fibrosis-related diseases, neurodegenerative/neurological diseases and cancer.Type: ApplicationFiled: May 23, 2018Publication date: December 13, 2018Inventors: Tim Johnson, Phil Watson, David Matthews, Alex Brown
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Patent number: 10005846Abstract: The invention provides antibodies and antigen-binding fragments thereof that selectively bind to an epitope within the core region of transglutaminase type 2 (TG2). Novel epitopes within the TG2 core are provided. The invention provides human TG2 inhibitory antibodies and uses thereof, particularly in medicine, for example in the treatment and/or diagnosis of conditions including Celiac disease, scarring, fibrosis-related diseases, neurodegenerative/neurological diseases and cancer.Type: GrantFiled: May 24, 2013Date of Patent: June 26, 2018Assignee: LifeArcInventors: Tim Johnson, Phil Watson, David Matthews, Alex Brown
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Publication number: 20180093033Abstract: A system for controlling the position of a diaphragm in a diaphragm-containing pressure pod, is provided. The system can include a peristaltic pump, a pressure pod having a flow-through fluid side and a gas side that are separated by a diaphragm, and a pressure sensor operatively connected to the gas side. The pressure sensor is configured to sense pulses of pressure resulting from movement of the diaphragm and caused by the action of the peristaltic pump. A gas source and a valve can be in fluid communication with the gas side of the pressure pod and can be configured to provide gas to, or vent gas from, the gas side. A controller receives pressure signals from the pressure sensor and controls the valve in response, and in so doing, controls the position of the diaphragm. Methods for positioning the diaphragm are also included.Type: ApplicationFiled: December 5, 2017Publication date: April 5, 2018Inventors: Martin Crnkovich, Lee Tanenbaum, Michael Emmanuel Kotsos, Fei Wang, Alex Brown
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Patent number: 9877407Abstract: The disclosed apparatus may include at least one physical extension handle that connects to at least one ejector that facilitates securing a line card to a chassis of a telecommunications system and ejecting the line card from the chassis of the telecommunications system. The physical extension handle may, when connected to the ejector, extend the ejector such that a user is able to access the ejector by way of the physical extension handle to secure the line card to or eject the line card from the chassis of the telecommunications system using the physical extension handle. Additionally or alternatively, the physical extension handle may facilitate physically supporting one or more communication cables connected to the line card in a horizontal orientation such that the communication cables avoid hanging down vertically directly from the chassis. Various other apparatuses and systems are also disclosed.Type: GrantFiled: September 30, 2015Date of Patent: January 23, 2018Assignee: Juniper Networks, Inc.Inventors: Henry K. Sim, Ken R. Weber, Mahesh Nagarajan, Brian J. Ray, Adolpho Gonzalez, Alex Brown, Tark Abed
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Patent number: D1058821Type: GrantFiled: June 25, 2019Date of Patent: January 21, 2025Inventors: Todd Brown, Alex Don Brown, Caleb Teague