Abstract: The presently disclosed inventive concepts relate generally to lift chairs, such as a lift chair comprising a frame having a back portion and a front portion defining an interior space, and a first horizontal member positioned between the back portion and the front portion; a foot platform positioned at least partially in the interior space of the frame, the foot platform having a lowered position and a raised position; a seat positioned at least partially in the interior space of the frame and above the platform and pivotally connected to the first horizontal member, the seat having a first end portion and a second end portion, and pivotable between a standing position and a seated position; and a motion translation system configured such that pivoting the seat between the standing position and the seated position moves the platform vertically between the lowered position and the raised position.

Abstract: Disclosed are methods of treating HIV infections comprising, in one aspect, administering compounds that are phospholipase D inhibitors. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: A system for controlling the position of a diaphragm in a diaphragm-containing pressure pod, is provided. The system can include a peristaltic pump, a pressure pod having a flow-through fluid side and a gas side that are separated by a diaphragm, and a pressure sensor operatively connected to the gas side. The pressure sensor is configured to sense pulses of pressure resulting from movement of the diaphragm and caused by the action of the peristaltic pump. A gas source and a valve can be in fluid communication with the gas side of the pressure pod and can be configured to provide gas to, or vent gas from, the gas side. A controller receives pressure signals from the pressure sensor and controls the valve in response, and in so doing, controls the position of the diaphragm. Methods for positioning the diaphragm are also included.

Abstract: System and methods are provided for displaying objects at a treatment display screen coupled to an apparatus for performing a treatment. A first arrangement of the objects is presented at the treatment display screen. At least some objects of the first arrangement of the objects are in a fixed state on the treatment display screen. A rearrangement mode of operation of the treatment display screen is activated. The objects of the first arrangement of the objects are changed from the fixed state to a fluid state that allows for rearrangement of the objects of the first arrangement of the objects to a second arrangement of the objects that is different than the first arrangement of the objects. The treatment is prevented from being performed during operation in the rearrangement mode. The second arrangement of the objects is presented at the treatment display screen during operation in the rearrangement mode.

Abstract: Disclosed are isoform selective Phospholipase D inhibitors. In one aspect, the disclosed compounds can have a structure represented by a formula (I): Also disclosed are methods of making and using the compounds. Also disclosed are pharmaceutical compositions and kits comprising the compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: The invention provides antibodies and antigen-binding fragments thereof that selectively bind to an epitope within the core region of transglutaminase type 2 (TG2). Novel epitopes within the TG2 core are provided. The invention provides human TG2 inhibitory antibodies and uses thereof, particularly in medicine, for example in the treatment and/or diagnosis of conditions including Celiac disease, scarring, fibrosis-related diseases, neurodegenerative/neurological diseases and cancer.

Abstract: A system for controlling the position of a diaphragm in a diaphragm-containing pressure pod, is provided. The system can include a peristaltic pump, a pressure pod having a flow-through fluid side and a gas side that are separated by a diaphragm, and a pressure sensor operatively connected to the gas side. The pressure sensor is configured to sense pulses of pressure resulting from movement of the diaphragm and caused by the action of the peristaltic pump. A gas source and a valve can be in fluid communication with the gas side of the pressure pod and can be configured to provide gas to, or vent gas from, the gas side. A controller receives pressure signals from the pressure sensor and controls the valve in response, and in so doing, controls the position of the diaphragm. Methods for positioning the diaphragm are also included.

Abstract: Disclosed are methods of treating viral infections comprising, in one aspect, administering compounds that are phospholipase D inhibitors. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. In accordance with the purpose(s) of the invention, as embodied and broadly described herein, the invention, in one aspect, relates to antiviral therapies. For example, compounds having Phospholipase D activity (e.g., isoform selective Phospholipase D inhibitors) can be useful in antiviral therapies (e.g., influenza treatments).

Abstract: Disclosed are methods of treating viral infections or disorders of uncontrolled proliferation comprising, in one aspect, administering compounds that are phospholipase D inhibitors and/or Akt therapeutic agents. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: Disclosed are methods of treating HIV infections comprising, in one aspect, administering compounds that are phospholipase D inhibitors. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: System and methods are provided for displaying objects at a treatment display screen coupled to an apparatus for performing a treatment. A first arrangement of the objects is presented at the treatment display screen. At least some objects of the first arrangement of the objects are in a fixed state on the treatment display screen. A rearrangement mode of operation of the treatment display screen is activated. The objects of the first arrangement of the objects are changed from the fixed state to a fluid state that allows for rearrangement of the objects of the first arrangement of the objects to a second arrangement of the objects that is different than the first arrangement of the objects. The treatment is prevented from being performed during operation in the rearrangement mode. The second arrangement of the objects is presented at the treatment display screen during operation in the rearrangement mode.

Abstract: Disclosed are isoform selective Phospholipase D inhibitors. In one aspect, the disclosed compounds can have a structure represented by a formula (I): Also disclosed are methods of making and using the compounds. Also disclosed are pharmaceutical compositions and kits comprising the compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: The invention relates to a novel purified recombinant ?V?3 adhesion receptor which shows an unimpaired ligand binding activity, and a process for preparing said soluble non-membrane bound receptor in excellent yields by recombinant techniques using a baculovirus-insect cell expression system. The so-synthesized soluble receptor may be used very easily as screening tool for new therapeutic compounds which may inhibit the natural ?V?3 adhesion receptor. Such therapeutic compounds which can be discovered very easily, fast and without health risk by means of the soluble receptors according to the invention may be, for example, RGD peptides or non-peptidic compounds mimicking the natural ligand epitopes. The invention relates, furthermore, to a corresponding process for preparing recombinant full-length ?V?3 adhesion receptor in excellent yields, additionally using detergents to dissolve the membrane bound receptor from the surface of the host cell.

Abstract: A partitioning technique utilized by a translator to divide the subject code space into regions, referred to hereafter as partitions, where each partition contains a distinct set of basic blocks of subject code and corresponding target code. The partitioning technique divides the translator's representation of subject code and subject code translations into non-overlapping regions of subject memory. In this manner, when the subject program modifies subject code, only those partitions actually affected by the self-modifying code need be discarded and all translations in unaffected partitions can be kept. This partitioning technique is advantageous in limiting the amount of target code that must be retranslated in response to self-modifying code operation. In another process, the partitioning technique allows multithreaded subject programs that also involve self-modifying code to perform code modification in a thread-safe manner.

Abstract: A native binding technique is provided for inserting calls to native functions during translation of subject code to target code, such that function calls in the subject program to subject code functions are replaced in target code with calls to native equivalents of the same functions. Parameters of native function calls are transformed from target code representations to be consistent with native code representations, native code calling conventions, and native function prototypes.

Abstract: A native binding technique is provided for inserting calls to native functions during translation of subject code to target code, such that function calls in the subject program to subject code functions are replaced in target code with calls to native equivalents of the same functions. Parameters of native function calls are transformed from target code representations to be consistent with native code representations, native code calling conventions, and native function prototypes.

Abstract: An improved method and apparatus for performing program code conversion is provided and, more particularly, for generating improved intermediate representations for use in program code conversion. During program code conversion, a partial dead code elimination optimization technique is implemented to identify partially dead register definitions within a block of program code being translated. The partial dead code elimination is an optimization to the intermediate representation in the form of code motion for blocks of program code ending in non-computed branches or computed jumps, where target code for all dead child nodes of a partially dead register definition is prevented from being generated and target code for partially dead child nodes of a partially dead register definition is delayed from being generated until after target code is generated for all fully live child nodes for the partially dead register definition.

Abstract: The invention relates to a novel purified recombinant ?V?3 adhesion receptor which shows an unimpaired ligand binding activity, and a process for preparing said soluble non-membrane bound receptor in excellent yields by recombinant techniques using a baculovirus-insect cell expression system. The so-synthesized soluble receptor may be used very easily as screening tool for new therapeutic compounds which may inhibit the natural ?v?3 adhesion receptor. Such therapeutic compounds which can be discovered very easily, fast and without health risk by means of the souluble receptors according to the invention may be, for example, RGD peptides or non-peptidic compounds mimicking the natural ligand epitopes. The invention relates, furthermore, to a corresponding process for preparing recombinant full-length ?V?3 adhesion receptor in excellent yields, additionally using detergents to dissolve the membrane bound receptor from the surface of the host cell.