Abstract: Provided herein are nucleic acid constructs, host insect cells, and methods for producing recombinant AAV capsids with high potency at high yield.

Abstract: Implementations described herein relate to methods, systems, and computer-readable media to automatically present suitable content for a particular audience. In some implementations, a computer-implemented method receiving virtual experience content associated with a first virtual experience associated with a first target audience and including content that is restricted as not viewable by a second target audience, receiving at least one content alternative, generating a first rating for the received virtual experience content and a second rating for the at least one content alternative, and automatically providing only one of the received virtual experience content or the at least one content alternative to user devices based on the first rating and the second rating.

Abstract: A receptacle connector assembly includes a receptacle cage having shielding walls including a top wall, a first side wall extending from the top wall to a bottom of the receptacle cage, and a second side wall extending from the top wall opposite the first side wall to the bottom of the receptacle cage. The receptacle connector assembly includes an EMI shield coupled to the receptacle cage at the front end. The EMI shield has a shield member including a base electrically connected to the receptacle cage and spring fingers that extend from the base to distal ends. The EMI shield includes a gasket between the receptacle cage and the corresponding spring fingers. The gasket electrically connects the corresponding spring fingers to the receptacle cage.

Abstract: An apparatus for bioprocessing includes a housing, a drawer receivable within the housing, the drawer including a plurality of sidewalls and a bottom defining a processing chamber, and a generally open top, the drawer being movable between a closed position in which the drawer is received within the housing, and an open position in which the drawer extends from the housing enabling access to the processing chamber through the open top, and at least one bed plate positioned within the processing chamber and configured to receive a bioreactor vessel.

Abstract: An example method comprising requesting authorization to reprocess a replaceable supply component using first data stored in memory of the replaceable supply component and an interface, the first data including original manufacturing data for the replaceable supply component. The method further comprises, in response to the request, receiving second data using the interface, and appending the original manufacturing data stored in the memory with the second data to designate the replaceable supply component as reprocessed.

Abstract: An oximetry device sealed in a sheath directs a user to allow the oximetry device to make oximetry measurements at a number of different tissue locations of a patient and average two or more of the oximetry measurements by directing the lifts and placements of the oximetry device and sheath to and from the different tissue locations and detecting the lift and placements. The averages are generated and displayed on a display of the device for the oximetry measurements if the lifts are made while use directions for the lifts are displayed on a display of the oximetry device. The averages are not generated if the lifts are not made while the user directions for the lifts are not displayed. The averages are simultaneously displayed with the oximetry measurements which are instantaneous measurement for patient tissue.

Abstract: A resin including up to 99.99 weight percent (wt. %) of a first polyolefin grafted with a functional group selected from an ethylenically unsaturated carboxylic acid, a carboxylic acid anhydride, an ester functional group or a combination thereof; and 0.01 to 3.0 wt. % of a tin oxide-based catalyst, where the resin includes 0.2 wt. % to 1.5 wt. % of the functional group from the first polyolefin, the wt. % based on a total weight of the resin. The first polyolefin can be selected from a polyethylene, a polypropylene, an ethylene/alpha-olefin copolymer, a propylene/alpha-olefin copolymer and combinations thereof. The tin oxide-based catalyst can be selected from dibutyltin oxide, dioctyltin oxide and combinations thereof. The resin can be used in a multilayer structure, where a Layer A comprises the resin and a Layer B comprises a polyester, where a first major surface of Layer A is in adhering contact with the second major surface of Layer B.

Abstract: The present disclosure relates to methods and intermediates useful for preparing a compound of formula I: or a co-crystal, solvate, salt or combination thereof.

Abstract: In one embodiment, a lidar system includes a light source configured to emit (i) local-oscillator light and (ii) pulses of light, where each emitted pulse of light is coherent with a corresponding portion of the local-oscillator light. The lidar system also includes a receiver configured to detect the local-oscillator light and a received pulse of light, the received pulse of light including light from one of the emitted pulses of light that is scattered by a target located a distance from the lidar system. The local-oscillator light and the received pulse of light are coherently mixed together at the receiver. The lidar system further includes a processor configured to determine the distance to the target based at least in part on a time-of-arrival for the received pulse of light.

Abstract: An electronic assembly includes an electronic package having an integrated circuit component and interposer assemblies with compressible interposer contacts electrically connected thereto. Cable connector modules are coupled to the interposer assemblies. A cover assembly is coupled to the upper surface of the electronic package over the cable connector modules. The cover assembly includes bridge assemblies having plates in a plate stack that are independently movable. A load plate engages upper edges of the plates of the bridge assemblies and press against the plates to drive the bridge assemblies into the cable connector modules using compression hardware. The cable connector modules compress the interposer contacts of the interposer assemblies when the load plate presses the plates of the bridge assemblies into the cable connector modules.

Abstract: Certain aspects relate to systems and techniques for a bipolar medical instrument. In one aspect, the medical instrument includes a first end effector, a first set of one or more distal pulleys coupled to the first end effector, and a wrist configured to house the first set of distal pulleys. The medical instrument also includes a plurality of cables extending through the wrist and a first insulating member formed between the first end effector and the first set of one or more distal pulleys.

Abstract: An apparatus for bioprocessing includes a housing, a drawer receivable within the housing, the drawer including a plurality of sidewalls and a bottom defining a processing chamber, and a generally open top, the drawer being movable between a closed position in which the drawer is received within the housing, and an open position in which the drawer extends from the housing enabling access to the processing chamber through the open top, and at least one bed plate positioned within the processing chamber and configured to receive a bioreactor vessel.

Abstract: In at least one embodiment, the liquid circulation system comprises a rotor located within a tank, a stator having a plurality of coils outside the tank, and an exterior tank wall that is non-magnetic and that is located next to the rotor and between the rotor and the stator, wherein an axis (R) of rotation of the rotor is in parallel with the exterior tank wall, the coils of the stator are arranged along the axis (R) of rotation of the rotor so that the rotor is configured to be rotated by the stator in a touchless manner through the exterior tank wall by means of a varying electromagnetic field driven by the stator to circulate a liquid within the tank.

Abstract: A bioprocessing system includes a first module configured for enriching and isolating a population of cells, a second module configured for activating, genetically modifying, and expanding the population of cells, and a third module configured for harvesting the expanded population of cells.

Abstract: A phased array ultrasonic testing device for positioning first and second phased array probes relative to a surface of a material to be tested. The testing device includes a first wedge configured to receive and orient the first phased array probe relative to the surface. A second wedge is configured to receive and orient the second phased array probe relative to the surface. A coupling structure is mounted to the first and second wedges and configured to selectively provide for the first and second wedges to move parallel to one another in a first direction and restrict relative movement of the first and second wedges in other directions.

Abstract: An oximeter probe that takes into account tissue color (e.g., skin color or melanin content) to improve accuracy when determining oxygen saturation of tissue. Light is transmitted from a light source into tissue having melanin (e.g., eumelanin or pheomelanin). Light reflected from the tissue is received by a detector. A compensation factor is determined to account for absorption due to the melanin. The oximeter uses this compensation factor and determines a melanin-corrected oxygen saturation value.

Abstract: In one embodiment, a lidar system includes a wavelength-tunable light source configured to emit pulses of light, each emitted pulse of light having a particular wavelength of multiple different wavelengths. The lidar system also includes a scanner configured to scan the emitted pulses of light across a field of regard of the lidar system. The scanner includes (i) a beam deflector configured to angularly deflect each emitted pulse of light along a first scan axis according to the particular wavelength of the emitted pulse of light and (ii) a scan mirror configured to scan the emitted pulses of light along a second scan axis different from the first scan axis. The lidar system further includes a receiver configured to detect a received pulse of light that includes a portion of one of the emitted pulses of light scattered by a target located a distance from the lidar system.

Abstract: Implementations described herein relate to methods, systems, and computer-readable media to automatically present suitable content for a particular audience. In some implementations, a computer-implemented method receiving virtual experience content associated with a first virtual experience associated with a first target audience and including content that is restricted as not viewable by a second target audience, receiving at least one content alternative, generating a first rating for the received virtual experience content and a second rating for the at least one content alternative, and automatically providing only one of the received virtual experience content or the at least one content alternative to user devices based on the first rating and the second rating.

Abstract: An oximeter device determines an oxygen saturation for the tissue and determines a quality value for the oxygen saturation and associated measurements of the tissue. The quality value is calculated from reflectance data received at the detectors of the oximeter device. An accelerometer of the oximeter device can detect movement of the oximeter device when oximetry measurements are made by the oximeter device. An amount of the movement is an indicator of a probe face of the oximeter device changing position with respect to the tissue when the measurements are made. The accelerometer information is used by the oximeter device to adjust the quality value to reflect the amount movement. The oxygen saturation and the adjusted quality metric value are displayed on a display of the oximeter device so that a user may view the quality of the displayed information.

Abstract: Systems for energizing a drain cleaning cable within a drain line or other region of interest are described. A signal transmitter on an end portion of the cable enables the cable end portion to be sensed or located when in a pipe or conduit underground. Also described are electrically conductive drivetrains for transferring rotary power.