Patents by Inventor Alexander Ernst

Alexander Ernst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20050032816
    Abstract: Substituted N-oxidanthranilamide derivatives, their production and use as pharmaceutical agents for treating diseases that are triggered by persistent angiogenesis are described. The compounds according to the invention can be used as or in the case of psoriasis, Kaposi's sarcoma, restenosis, endometriosis, Crohn's disease, Hodgkin's disease, leukemia; arthritis, such as rheumatoid arthritis, hemangioma, angiofibroma; eye diseases, such as diabetic retinopathy, neovascular glaucoma; renal diseases, such as glomerulonephritis, diabetic nephropathy, malignant nephrosclerosis, thrombic microangiopathic syndrome, transplant rejections and glomerulopathy; fibrotic diseases, such as cirrhosis of the liver, mesangial cell proliferative diseases, arteriosclerosis, injuries to nerve tissue, and inhibition of the reocclusion of vessels after balloon catheter treatment, in vascular prosthetics or after mechanical devices are used to keep vessels open, such as, e.g.
    Type: Application
    Filed: May 3, 2002
    Publication date: February 10, 2005
    Inventors: Alexander Ernst, Andreas Huth, Martin Krueger, Karl-Heniz Thierauch, Andreas Menrad, Martin Haberey
  • Publication number: 20040266770
    Abstract: Substituted cyanoanthranilamide derivatives, their production and use as pharmaceutical agents for treating diseases that are triggered by persistent angiogenesis are described. The compounds according to the invention can be used as or in the case of psoriasis, Kaposi's sarcoma, restenosis, such as, e.g., stent-induced restenosis, endometriosis, Crohn's disease, Hodgkin's disease, leukemia; arthritis, such as rheumatoid arthritis, hemangioma, angiofibroma; eye diseases, such as diabetic retinopathy, neovascular glaucoma; renal diseases, such as glomerulonephritis, diabetic nephropathy, malignant nephrosclerosis, thrombic microangiopathic syndrome, transplant rejections and glomerulopathy; fibrotic diseases, such as cirrhosis of the liver, mesangial cell proliferative diseases, arteriosclerosis, injuries to nerve tissue, and inhibition of the reocclusion of vessels after balloon catheter treatment, in vascular prosthetics or after mechanical devices are used to keep vessels open, such as, e.g.
    Type: Application
    Filed: August 25, 2004
    Publication date: December 30, 2004
    Inventors: Alexander Ernst, Andreas Huth, Martin Krueger, Karl-Heinz Thierauch, Andreas Menrad, Martin Haberey
  • Publication number: 20040254185
    Abstract: Selective anthranilamide pyridinamides as VEGFR-2 and VEGFR-3 inhibitors, their production and use as pharmaceutical agents for treating diseases that are triggered by persistent angiogenesis are described. The compounds according to the invention can be used as or in the case of psoriasis, Kaposi's sarcoma, restenosis, such as, e.g.
    Type: Application
    Filed: June 23, 2004
    Publication date: December 16, 2004
    Inventors: Alexander Ernst, Andreas Huth, Martin Kruger, Karl-Heinz Thierauch, Andreas Menrad, Martin Haberey
  • Publication number: 20040186156
    Abstract: Substituted N-(1,4,5,6-tetrahydro-cyclopentapyrazol-3-yl) derivatives, their production, as well as intermediate products for their production, and the use as pharmaceutical agents for treating various diseases are described.
    Type: Application
    Filed: March 25, 2004
    Publication date: September 23, 2004
    Inventors: Martin Kruger, Olaf Prien, Andreas Steinmeyer, Jorg Kroll, Alexander Ernst, Gerhard Siemeister, Martin Haberey, Jens Hoffmann
  • Patent number: 6747046
    Abstract: Substituted N-(1,4,5,6-tetrahydro-cyclopentapyrazol-3-yl) derivatives, their production, as well as intermediate products for their production, and the use as pharmaceutical agents for treating various diseases are described.
    Type: Grant
    Filed: September 25, 2002
    Date of Patent: June 8, 2004
    Assignee: Schering Aktiengesellschaft
    Inventors: Martin Krüger, Olaf Prien, Andreas Steinmeyer, Jörg Kroll, Alexander Ernst, Gerhard Siemeister, Martin Haberey, Jens Hoffmann
  • Publication number: 20040102441
    Abstract: Ortho-substituted anthranilic acid amides and use thereof as pharmaceutical agents for treating diseases that are triggered by persistent angiogenesis are described.
    Type: Application
    Filed: June 24, 2003
    Publication date: May 27, 2004
    Inventors: Martin Krueger, Andreas Huth, Orlin Petrov, Dieter Seidelmann, Karl-Heinz Thierauch, Martin Haberey, Andreas Menrad, Alexander Ernst
  • Publication number: 20040063737
    Abstract: This invention relates to 2-heteroaryl-pyrimidine derivatives of general formula I as inhibitors of the cyclin-dependent kinases, their production as well as their use as medications for treating various diseases.
    Type: Application
    Filed: October 27, 2003
    Publication date: April 1, 2004
    Applicant: Schering AG
    Inventors: Ulrich Lucking, Martin Kruger, Rolf Jautelat, Olaf Prien, Gerhard Siemeister, Alexander Ernst
  • Publication number: 20040029880
    Abstract: Substituted anthranilamides and use thereof as pharmaceutical agents for treating diseases that are triggered by persistent angiogenesis as well as their intermediate products for the production of anthranilamides are described.
    Type: Application
    Filed: June 23, 2003
    Publication date: February 12, 2004
    Inventors: Martin Krueger, Andreas Huth, Orlin Petrov, Dieter Seidelmann, Karl-Heinz Thierauch, Martin Haberey, Andreas Menrad, Alexander Ernst
  • Publication number: 20030212121
    Abstract: Substituted N-(1,4,5,6-tetrahydro-cyclopentapyrazol-3-yl) derivatives, their production, as well as intermediate products for their production, and the use as pharmaceutical agents for treating various diseases are described.
    Type: Application
    Filed: September 25, 2002
    Publication date: November 13, 2003
    Inventors: Martin Kruger, Olaf Prien, Andreas Steinmeyer, Jorg Kroll, Alexander Ernst, Gerhard Siemeister, Martin Haberey, Jens Hoffman
  • Patent number: 5940787
    Abstract: A method and apparatus for monitoring the condition of a tool or a workpiece includes an electromagnetic energy source for directing electromagnetic energy toward the tool and also receives electromagnetic energy reflected off the tool. A detector is arranged to receive the reflected electromagnetic energy from the electromagnetic energy source and converts the reflected energy into electronic signals. The electronic signals are transmitted from the detector to a control signal generator and then to a signal analyzing device. The signal analyzing device compares the electronic signals received from the control signal generator to reference signals to determine the condition of the tool or workpiece. Then, the control signal generator generates a control signal based on the result of the comparison performed by the signal analyzing device and transmits the control signal to a tool controlling device controlling the operation of the tool.
    Type: Grant
    Filed: December 14, 1995
    Date of Patent: August 17, 1999
    Assignee: U.S. Tech Corporation
    Inventor: Alexander Ernst Gelston