Patents by Inventor Alexander H. Cooper
Alexander H. Cooper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240081994Abstract: A steerable delivery system is provided for delivering a replacement heart valve to a native heart valve location. The steerable delivery system includes an outer sheath assembly having a capsule along a distal end portion for retaining the replacement heart valve in a compressed configuration. The capsule is constructed to provide both compression resistance and flexibility. The capsule may be formed with an outer polymer layer, a metal middle layer located on a radially inner surface of the outer polymer layer, and an inner liner located on a radially inner surface of the metal middle layer. A fluoroelastomer layer is provided for bonding the inner liner to the metal middle layer. The metal middle layer is preferably a metal hypotube.Type: ApplicationFiled: November 21, 2023Publication date: March 14, 2024Inventors: Alexander H. Cooper, David Robert Landon, Kevin M. Stewart, Garrett Dallas Johnson, Glen T. Rabito, Tarannum Ishaq Gutierrez, Hiroshi Okabe, Ramon Aguilar, JR., Jesse Robert Edwards, Taylor Jacob Scheinblum, Patrick Chow, Julio Cesar Sanchez, Hieu Minh Luong
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Publication number: 20240041602Abstract: In one example, an implantable prosthetic device comprises a spacer body portion configured to be disposed between native leaflets of a heart, and an anchor portion configured to secure the native leaflets against the spacer body portion. The prosthetic device can be movable between multiple configurations. A size of the spacer body is configured to be adjusted after the spacer body is placed between the native valve leaflets and the pair of anchors are placed against the ventricular surfaces of the native heart valve leaflets. A delivery apparatus can have a first shaft and a second shaft, wherein movement of the first shaft relative to the second shaft moves the anchor portion relative to the spacer body.Type: ApplicationFiled: October 18, 2023Publication date: February 8, 2024Inventors: Mark Chau, David M. Taylor, Alexander J. Siegel, Christopher J. Olson, Sergio Delgado, Alexander H. Cooper, Lauren R. Freschauf, Asher L. Metchik, Matthew T. Winston, Cristobal R. Hernandez, Emil Karapetian, Bao Khuu, Eric Robert Dixon, Amanda French, Philip P. Corso, JR.
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Patent number: 11883030Abstract: Various systems, devices, components and methods are disclosed for controllably and selectively occluding, restricting, and/or diverting flow within a patient's vasculature. The flow restriction systems can include an implant having a flow restrictor and an implantable controller having an actuator for actuating the flow restrictor. The flow restriction systems can also include an external device for controlling operation of the implant via the implantable controller.Type: GrantFiled: April 13, 2023Date of Patent: January 30, 2024Assignee: inQB8 Medical Technologies, LLCInventors: Arshad Quadri, J. Brent Ratz, Alexander H. Cooper, Juliet Laura Schwartz
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Patent number: 11883287Abstract: Devices, systems and methods are described herein to provide improved steerability for delivering a prosthesis to a body location, for example, for delivering a replacement mitral valve to a native mitral valve location. The steerable delivery system can contain a steerable rail configured for multi-plane bending to direct a distal end of the delivery system.Type: GrantFiled: October 15, 2020Date of Patent: January 30, 2024Assignee: EDWARDS LIFESCIENCES CORPORATIONInventors: Alexander H. Cooper, David Robert Landon, Kevin M. Stewart, Garrett Dallas Johnson, Glen T. Rabito, Tarannum Ishaq Gutierrez, Hiroshi Okabe, Ramon Aguilar, Jr., Jesse Robert Edwards, Taylor Jacob Scheinblum, Patrick Chow, Julio Cesar Sanchez, Hieu Minh Luong
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Publication number: 20230414360Abstract: Various systems, devices, components and methods are disclosed for controllably and selectively occluding, restricting, and/or diverting flow within a patient's vasculature. The flow restriction systems can include an implant having a flow restrictor and an implantable controller having an actuator for actuating the flow restrictor. The flow restriction systems can also include an external device for controlling operation of the implant via the implantable controller.Type: ApplicationFiled: September 6, 2023Publication date: December 28, 2023Inventors: Arshad QUADRI, J. Brent RATZ, Alexander H. Cooper, Juliet Laura Schwartz
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Publication number: 20230404753Abstract: A delivery system includes a suture attachment mechanism for maintaining a connection to a heart valve after initial deployment, thereby allowing recapture of the heart valve if desired. A plurality of suture portions is provided along a distal end portion of the delivery system, each suture portion having a first end fixed to the delivery system and a second end releasably coupled to a retention member on the delivery system. A knob on a handle of the delivery system is actuated for causing the second end of each suture portion to be released from its respective retention member, thereby allowing the suture portions to be decoupled from the heart valve. The suture portions are located only along a distal end portion of the delivery system for improving reliability and consistency.Type: ApplicationFiled: August 7, 2023Publication date: December 21, 2023Inventors: Hieu Minh Luong, Julio Cesar Sanchez, Alexander H. Cooper, Jesse Robert Edwards, Hiroshi Okabe, Karen Fromell Nesbitt, David Robert Landon, Nikolai Brent Poulsen, Taylor Jacob Scheinblum, Eric Robert Dixon, Cooper Ryan Rickerson, Zachary Charles VanEvery
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Patent number: 11826252Abstract: A method of replacing the function of a native heart valve is achieved by inserting a distal end portion of a delivery apparatus into a patient's body, wherein a prosthetic valve is disposed along the distal end portion of the delivery apparatus. The prosthetic valve includes a collapsible and expandable annular body having a network of struts interconnected at a plurality of nodes to form a plurality of open cells. Atrial and ventricular flanges are coupled to the annular body and extend radially away from the annular body. The annular body includes three commissure support posts of fixed length that extend substantially the entire length of the annular body. A valve member is secured to the commissure support posts. The annular body is radially expanded within the native heart valve and the atrial and ventricular flanges are deployed on opposite sides of the native heart valve.Type: GrantFiled: December 18, 2020Date of Patent: November 28, 2023Assignee: EDWARDS LIFESCIENCES CORPORATIONInventors: Alexander H. Cooper, Matthew A. Peterson
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Publication number: 20230363906Abstract: An assembly includes a delivery apparatus and a self-expandable prosthetic heart valve including radially extendable atrial protrusions and radially extendable ventricular protrusions. The prosthetic valve further includes a valve member supported by an annular body having the atrial protrusions and the ventricular protrusions coupled thereto. The delivery apparatus includes a first (distal) capsule portion and a second (proximal) capsule portion for retaining the prosthetic valve in a radially compressed, delivery state. The first capsule portion can be moved distally to allow the ventricular protrusions to expand, and the second capsule portion can be proximally retracted to allow the atrial protrusions to expand and transition to prosthetic valve to a radially expanded state. When implanted, the atrial protrusions are configured to engage an atrial side of a native heart valve, and the ventricular protrusions are configured to engage the ventricular side of the native heart valve.Type: ApplicationFiled: July 26, 2023Publication date: November 16, 2023Inventors: Alexander H. Cooper, Matthew A. Peterson
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Publication number: 20230346381Abstract: Various systems, devices, components and methods are disclosed for controllably and selectively occluding, restricting, and/or diverting flow within a patient's vasculature. The flow restriction systems can include an implant having a flow restrictor and an implantable controller having an actuator for actuating the flow restrictor. The flow restriction systems can also include an external device for controlling operation of the implant via the implantable controller.Type: ApplicationFiled: April 13, 2023Publication date: November 2, 2023Inventors: Arshad QUADRI, J. Brent RATZ, Alexander H. Cooper, Juliet Laura Schwartz
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Patent number: 11793642Abstract: In one representative embodiment, an implantable prosthetic device comprises a spacer body portion configured to be disposed between native leaflets of a heart, and an anchor portion configured to secure the native leaflets against the spacer body portion. The prosthetic device can be movable between multiple configurations. The spacer body can be made from braided, self-expandable metallic thread. A delivery apparatus can have a first shaft and a second shaft, wherein movement of the first shaft relative to the second shaft moves the anchor portion relative to the spacer body.Type: GrantFiled: July 25, 2019Date of Patent: October 24, 2023Assignee: EDWARDS LIFESCIENCES CORPORATIONInventors: Mark Chau, David M. Taylor, Alexander J. Siegel, Christopher J. Olson, Sergio Delgado, Alexander H. Cooper, Lauren R. Freschauf, Asher L. Metchik, Matthew T. Winston, Cristobal R. Hernandez, Emil Karapetian, Bao Khuu, Eric Robert Dixon
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Publication number: 20230277309Abstract: A method of implanting a prosthetic heart valve at a native tricuspid valve region includes delivering a prosthetic heart valve to the native tricuspid valve region via the inferior vena cava or the superior vena cava and deploying the prosthetic heart valve from a sheath of a delivery apparatus. The prosthetic heart valve includes a radially compressible and expandable frame assembly having an inflow end, an outflow end, and a double-body structure having an annular inner frame and an annular outer frame. The outer frame preferably includes an atrial flange portion configured to contact an atrial face of the native tricuspid valve region. The prosthetic heart valve can further include a plurality of ventricular anchors, each comprising a free end portion and a fixed end portion connected to and extending from the frame assembly at a location spaced from the outflow end of the frame assembly.Type: ApplicationFiled: May 10, 2023Publication date: September 7, 2023Inventors: Alexander H. Cooper, Matthew A. Peterson, William C. Brunnett
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Patent number: 11730596Abstract: A method of replacing the function of a native heart valve is achieved by inserting a distal end portion of a delivery apparatus into a patient's body, wherein a prosthetic valve is disposed along the distal end portion of the delivery apparatus. The prosthetic valve includes a collapsible and expandable annular body having a network of struts interconnected at a plurality of nodes to form a plurality of open cells. Atrial and ventricular flanges are coupled to the annular body and extend radially away from the annular body. The annular body includes three commissure support posts of fixed length that extend substantially the entire length of the annular body. A valve member is secured to the commissure support posts. The annular body is radially expanded within the native heart valve and the atrial and ventricular flanges are deployed on opposite sides of the native heart valve.Type: GrantFiled: December 18, 2020Date of Patent: August 22, 2023Assignee: EDWARDS LIFESCIENCES CORPORATIONInventors: Alexander H. Cooper, Matthew A. Peterson
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Patent number: 11684471Abstract: Embodiments of a prosthetic heart valve comprise an annular main body, an atrial cap extending radially outwardly from the atrial end of the main body, and a plurality of ventricular anchors extending outwardly from the ventricular end of the main body. Each ventricular anchor can have a proximal end portion connected to the ventricular end, an intermediate portion extending away from the atrial end and then back toward the atrial so as to define a first bend, and a free distal end portion that extends from the intermediate portion. The distal end portion can comprise a first section, a second section, and a second bend between the first and second sections, the first section extending from the intermediate portion in a direction toward the atrial end and radially away from the main body.Type: GrantFiled: June 16, 2020Date of Patent: June 27, 2023Assignee: EDWARDS LIFESCIENCES CORPORATIONInventors: Alexander H. Cooper, Matthew A. Peterson, William C. Brunnett
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Publication number: 20230157814Abstract: A replacement mitral valve prosthesis includes a support structure and a valve body having three flexible leaflets. The support structure preferably includes an internal valve frame and an external sealing frame. The valve frame supports the flexible leaflets. The sealing frame is adapted to conform to the shape of the native mitral valve annulus. The sealing frame may be coupled to an inlet end of the valve frame, an outlet end of the valve frame, or both. A plurality of anchors is coupled to the outlet end of the valve frame. The anchors extend radially outwardly for placement behind native leaflets. The prosthesis preferably includes a skirt disposed along an exterior of the external sealing frame. The prosthesis is collapsible for delivery into the heart via a delivery catheter. The prosthesis is configured to self-expand for deployment in the heart when released from the delivery catheter.Type: ApplicationFiled: January 19, 2023Publication date: May 25, 2023Inventors: Travis Zenyo Oba, Matthew A. Peterson, Glen T. Rabito, Alexander H. Cooper, David Robert Landon, J. Brent Ratz, Seung-Beom Yi
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Publication number: 20230046495Abstract: A replacement mitral valve prosthesis includes a support structure and a valve body having three flexible leaflets. The support structure preferably includes an internal valve frame and an external sealing frame. The valve frame supports the flexible leaflets. The sealing frame is adapted to conform to the shape of the native mitral valve annulus. The sealing frame may be coupled to an inlet end of the valve frame, an outlet end of the valve frame, or both. A plurality of anchors is coupled to the outlet end of the valve frame. The anchors extend radially outwardly for placement behind native leaflets. The prosthesis preferably includes a skirt disposed along an exterior of the external sealing frame. The prosthesis is collapsible for delivery into the heart via a delivery catheter. The prosthesis is configured to self-expand for deployment in the heart when released from the delivery catheter.Type: ApplicationFiled: November 3, 2022Publication date: February 16, 2023Inventors: Travis Zenyo Oba, Matthew A. Peterson, Glen T. Rabito, Alexander H. Cooper, David Robert Landon, J. Brent Ratz, Seung-Beom Yi
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Publication number: 20230000624Abstract: Disclosed are embodiments of delivery systems for delivery of replacement heart valves. This can include mitral, aortic, tricuspid, and pulmonary valves. The delivery systems can include one or more different components and configurations that advantageously improve placement of the replacement heart valves during the operation of the delivery system.Type: ApplicationFiled: September 8, 2022Publication date: January 5, 2023Inventors: Hiroshi Okabe, Hieu Minh Luong, Julio Cesar Sanchez, Jesse Robert Edwards, Alexander H. Cooper, David Robert Landon
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Patent number: 11504229Abstract: A replacement mitral valve prosthesis includes a support structure and a valve body having three flexible leaflets. The support structure preferably includes an internal valve frame and an external sealing frame. The valve frame supports the flexible leaflets. The sealing frame is adapted to conform to the shape of the native mitral valve annulus. The sealing frame may be coupled to an inlet end of the valve frame, an outlet end of the valve frame, or both. A plurality of anchors is coupled to the outlet end of the valve frame. The anchors extend radially outwardly for placement behind native leaflets. The prosthesis preferably includes a skirt disposed along an exterior of the external sealing frame. The prosthesis is collapsible for delivery into the heart via a delivery catheter. The prosthesis is configured to self-expand for deployment in the heart when released from the delivery catheter.Type: GrantFiled: April 8, 2020Date of Patent: November 22, 2022Assignee: Edwards Lifesciences CorporationInventors: Travis Zenyo Oba, Matthew A. Peterson, Glen T. Rabito, Alexander H. Cooper, David Robert Landon, J. Brent Ratz, Seung-Beom Yi
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Publication number: 20220331102Abstract: Devices, systems and methods are described herein a prosthesis for implantation within a lumen or body cavity and delivery systems for delivering the prosthesis to a location for implantation. A delivery system can include a plurality of components, including a flexible nose cone, multi-layer sheath, and pre-compressed shaft, which can be moveable relative to each other.Type: ApplicationFiled: June 29, 2022Publication date: October 20, 2022Applicant: Edwards Lifesciences CardiAQ LLCInventors: Arshad Quadri, J. Brent Ratz, Yen Liao, Julio Cesar Sanchez, Alexander H. Cooper, Glen T. Rabito, Siddharth Vad, Luca Pesce, Kevin M. Stewart, David Robert Landon
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Publication number: 20220296352Abstract: In a particular embodiment, the present disclosure provides a prosthetic valve delivery assembly that includes a storage tube and a nose cone cap. A prosthetic valve having a frame is at least partially disposed within the storage tube. A nose cone is disposed about an elongated shaft. The nose cone cap and the storage tube have mating first and second locking member that can be coupled to selectively secure the nose cone cap to the storage tube.Type: ApplicationFiled: March 11, 2022Publication date: September 22, 2022Inventors: Alexander H. Cooper, Michael R. Bialas, David M. Taylor, Gregory Scott Tyler, II, Zachary R. Kowalski, Art Z. Kwan, Darshin S. Patel, Asher L. Metchik, Michael J. Popp, Amanda Kristine Anderson White
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Publication number: 20220287836Abstract: Devices, systems and methods are described herein to provide improved treatment of a tricuspid valve. Such treatment may include tricuspid valve replacement, which may include providing a prosthetic tricuspid valve within the tricuspid valve annulus. Delivery systems for delivering the prosthetic tricuspid valve to the tricuspid valve annulus are disclosed herein. Treatment may also include repair of the tricuspid valve.Type: ApplicationFiled: February 25, 2022Publication date: September 15, 2022Applicant: Edwards Lifesciences CorporationInventors: David Robert Landon, Taylor Jacob Scheinblum, Matthew Michael Becerra, Alexander H. Cooper, Jesse Robert Edwards, Hieu Minh Luong, David L. Hauser, Pui Tong Ho