Patents by Inventor Alexander H. Cooper
Alexander H. Cooper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 10350062Abstract: A prosthesis can be configured to grasp intralumenal tissue when deployed within a body cavity and prevent axial flow of fluid around an exterior of the prosthesis. The prosthesis can include an expandable frame configured to radially expand and contract for deployment within the body cavity and a valve body. The expandable frame can include a frame body and a supplemental frame. The valve body can include a plurality of leaflets and one or more intermediate components. The one or more intermediate components can couple at least a portion of the leaflets to the expandable frame. The prosthesis can include an annular flap positioned around an exterior of the expandable frame.Type: GrantFiled: July 18, 2017Date of Patent: July 16, 2019Assignee: Edwards Lifesciences CorporationInventors: Matthew A. Peterson, Seung-Beom Yi, Siddharth Vad, Travis Zenyo Oba, Lauren R. Freschauf, Amanda French, Yaron Keidar, Yuanlong Du, Gregory Bak-Boychuk, Kevin M. Golemo, Alexander H. Cooper
-
Publication number: 20190209322Abstract: Disclosed herein are devices for improving coaption of the mitral valve leaflets to reduce or eliminate mitral valve regurgitation. The devices may be used to perform mitral valve annuloplasty, or to serve as a docking station for a transcatheter prosthetic heart valve. The various embodiments of devices are configured for percutaneous and, in some cases, transvascular delivery. Delivery systems useful for routing the devices to the mitral valve are also disclosed, including catheters, balloons and/or mechanical expansion systems. The devices themselves include at least one tissue penetrating member. Methods of delivery include partially embedding the devices in the mitral valve annulus via at least one tissue penetrating member. Tissue penetrating members may be embedded into the tissue in a simultaneous or a nearly simultaneous fashion. Upon embedding, the devices employ various expansion and/or contraction features to adjust the mitral valve diameter.Type: ApplicationFiled: March 19, 2019Publication date: July 11, 2019Inventors: David M. Taylor, Tri D. Tran, Sean Chow, David L. Hauser, Pui Tong Ho, Alexander H. Cooper
-
Patent number: 10278819Abstract: Disclosed herein are devices for improving coaption of the mitral valve leaflets to reduce or eliminate mitral valve regurgitation. The devices may be used to perform mitral valve annuloplasty, or to serve as a docking station for a transcatheter prosthetic heart valve. The various embodiments of devices are configured for percutaneous and, in some cases, transvascular delivery. Delivery systems useful for routing the devices to the mitral valve are also disclosed, including catheters, balloons and/or mechanical expansion systems. The devices themselves include at least one tissue penetrating member. Methods of delivery include partially embedding the devices in the mitral valve annulus via at least one tissue penetrating member. Tissue penetrating members may be embedded into the tissue in a simultaneous or a nearly simultaneous fashion. Upon embedding, the devices employ various expansion and/or contraction features to adjust the mitral valve diameter.Type: GrantFiled: May 27, 2016Date of Patent: May 7, 2019Assignee: Edwards Lifesciences CorporationInventors: David M. Taylor, Tri D. Tran, Sean Chow, David L. Hauser, Pui Tong Ho, Alexander H. Cooper
-
Publication number: 20190008639Abstract: Devices, systems and methods are described herein to provide improved steerability for delivering a prosthesis to a body location, for example, for delivering a replacement mitral valve to a native mitral valve location. Disclosed are a number of features that can improve steerability or release of the prosthesis into the body location.Type: ApplicationFiled: July 5, 2018Publication date: January 10, 2019Inventors: David Robert Landon, Alexander H. Cooper, Julio Cesar Sanchez, Glen T. Rabito, Victoria Cheng-Tan Wu, Kevin M. Golemo, J. Brent Ratz, Tarannum Ishaq Gutierrez, Ramon Aguilar, JR., Taylor Jacob Scheinblum, Kevin M. Stewart, Garrett Dallas Johnson, Jesse Robert Edwards, Hieu Minh Luong, Lindsay Lam
-
Publication number: 20190008640Abstract: Devices, systems and methods are described herein to provide improved steerability for delivering a prosthesis to a body location, for example, for delivering a replacement mitral valve to a native mitral valve location. The steerable delivery system can contain a steerable rail configured for multi-plane bending to direct a distal end of the delivery system.Type: ApplicationFiled: July 5, 2018Publication date: January 10, 2019Inventors: Alexander H. Cooper, David Robert Landon, Kevin M. Stewart, Garrett Dallas Johnson, Glen T. Rabito, Tarannum Ishaq Gutierrez, Hiroshi Okabe, Ramon Aguilar, JR., Jesse Robert Edwards, Taylor Jacob Scheinblum, Patrick Chow, Julio Cesar Sanchez, Hieu Minh Luong
-
Publication number: 20180353295Abstract: A method of replacing the function of a native mitral valve is achieved by inserting a distal end portion of a delivery apparatus into a patient's body, wherein a prosthetic mitral valve is disposed along the distal end portion of the delivery apparatus. The prosthetic mitral valve includes a collapsible and expandable annular body having a network of struts interconnected at a plurality of nodes to form a plurality of open cells. Atrial and ventricular flanges are coupled to the annular body and extend radially away from the annular body. Three commissure support posts extend from the ventricular flange toward a ventricular end of the prosthetic valve and a valve member is secured to the commissure support posts. The prosthetic mitral valve is positioned within the native mitral valve of the patient's heart and the native mitral valve is pinched between the atrial and ventricular flanges.Type: ApplicationFiled: August 16, 2018Publication date: December 13, 2018Inventors: Alexander H. Cooper, Matthew A. Peterson
-
Publication number: 20180296338Abstract: Devices, systems and methods are described herein a prosthesis for implantation within a lumen or body cavity and delivery devices for delivering the prosthesis to a location for implantation. A delivery system can include a plurality of components which are moveable relative to each other. The delivery system can include a nose cone which can cover at least a first end of the prosthesis, an outer elongate member which can cover at least a second end of the prosthesis, and a tether which can at least partially restrain the prosthesis from deployment.Type: ApplicationFiled: June 21, 2018Publication date: October 18, 2018Inventors: Glen T. Rabito, J. Brent Ratz, Luca Pesce, Arshad Quadri, Lindsay Lam, Yen Liao, Julio Cesar Sanchez, David Robert Landon, Garrett Dallas Johnson, Alexander H. Cooper
-
Publication number: 20180296336Abstract: Embodiments of a prosthetic heart valve comprise an annular main body, an atrial cap extending radially outwardly from the atrial end of the main body, and a plurality of ventricular anchors extending outwardly from the ventricular end of the main body. Each ventricular anchor can have a proximal end portion connected to the ventricular end, an intermediate portion extending away from the atrial end and then back toward the atrial so as to define a first bend, and a free distal end portion that extends from the intermediate portion. The distal end portion can comprise a first section, a second section, and a second bend between the first and second sections, the first section extending from the intermediate portion in a direction toward the atrial end and radially away from the main body.Type: ApplicationFiled: June 21, 2018Publication date: October 18, 2018Inventors: Alexander H. Cooper, Matthew A. Peterson, William C. Brunnett
-
Patent number: 10058424Abstract: Embodiments of prosthetic valve frames for implantation within a native mitral valve can include a main body portion, and first and second radially extending flanges coupled to the main body portion. The flanges can be coupled to the main body such that the flanges are spaced father apart from one another when the main body portion is in a crimped configuration than when the main body portion is in an expanded configuration. Associated delivery systems and methods of delivery are provided.Type: GrantFiled: August 19, 2015Date of Patent: August 28, 2018Assignee: Edwards Lifesciences CorporationInventors: Alexander H. Cooper, Matthew A. Peterson
-
Patent number: 10010414Abstract: Embodiments of a prosthetic heart valve comprise an annular main body, an atrial cap extending radially outwardly from the atrial end of the main body, and a plurality of ventricular anchors extending outwardly from the ventricular end of the main body. Each ventricular anchor can have a proximal end portion connected to the ventricular end, an intermediate portion extending away from the atrial end and then back toward the atrial so as to define a first bend, and a free distal end portion that extends from the intermediate portion. The distal end portion can comprise a first section, a second section, and a second bend between the first and second sections, the first section extending from the intermediate portion in a direction toward the atrial end and radially away from the main body.Type: GrantFiled: December 16, 2016Date of Patent: July 3, 2018Assignee: Edwards Lifesciences CorporationInventors: Alexander H. Cooper, Matthew A. Peterson, William C. Brunnett
-
Patent number: 10004599Abstract: Devices, systems and methods are described herein a prosthesis for implantation within a lumen or body cavity and delivery devices for delivering the prosthesis to a location for implantation. A delivery system can include a plurality of components which are moveable relative to each other. The delivery system can include a nose cone which can cover at least a first end of the prosthesis, an outer elongate member which can cover at least a second end of the prosthesis, and a tether which can at least partially restrain the prosthesis from deployment.Type: GrantFiled: February 20, 2015Date of Patent: June 26, 2018Assignee: Edwards Lifesciences CardiAQ LLCInventors: Glen T. Rabito, J. Brent Ratz, Luca Pesce, Arshad Quadri, Lindsay Lam, Yen Liao, Julio Cesar Sanchez, David Landon, Garrett Dallas Johnson, Alexander H. Cooper
-
Publication number: 20180055629Abstract: A replacement mitral valve prosthesis includes a support structure and a valve body having three flexible leaflets. The support structure preferably includes an internal valve frame and an external sealing frame. The valve frame supports the flexible leaflets. The sealing frame is adapted to conform to the shape of the native mitral valve annulus. The sealing frame may be coupled to an inlet end of the valve frame, an outlet end of the valve frame, or both. A plurality of anchors are coupled to the outlet end of the valve frame. The anchors extend radially outwardly for placement behind native leaflets. The prosthesis preferably includes a skirt disposed along an exterior of the external sealing frame. The prosthesis is collapsible for delivery into the heart via a delivery catheter. The prosthesis is configured to self-expand for deployment in the heart when released from the delivery catheter.Type: ApplicationFiled: August 25, 2017Publication date: March 1, 2018Applicant: Edwards Lifesciences CorporationInventors: Travis Zenyo Oba, Matthew A. Peterson, Glen T. Rabito, Alexander H. Cooper, David Robert Landon, J. Brent Ratz, Seung-Beom Yi
-
Publication number: 20180021129Abstract: A prosthesis can be configured to grasp intralumenal tissue when deployed within a body cavity and prevent axial flow of fluid around an exterior of the prosthesis. The prosthesis can include an expandable frame configured to radially expand and contract for deployment within the body cavity and a valve body. The expandable frame can include a frame body and a supplemental frame. The valve body can include a plurality of leaflets and one or more intermediate components. The one or more intermediate components can couple at least a portion of the leaflets to the expandable frame. The prosthesis can include an annular flap positioned around an exterior of the expandable frame.Type: ApplicationFiled: July 18, 2017Publication date: January 25, 2018Applicant: Edwards Lifesciences CorporationInventors: Matthew A. Peterson, Seung-Beom Yi, Siddharth Vad, Travis Zenyo Oba, Lauren R. Freschauf, Amanda French, Yaron Keidar, Yuanlong Du, Gregory Bak-Boychuk, Kevin M. Golemo, Alexander H. Cooper
-
Publication number: 20170156839Abstract: In a particular embodiment, the present disclosure provides a prosthetic valve delivery assembly that includes a storage tube. A prosthetic valve having a frame is at least partially disposed within the storage tube. A nose cone is located distally to the valve. A removable tab is disposed between the distal end of the frame and the nose cone. The tab assists in maintaining the position of the nose cone relative to the distal end of the frame.Type: ApplicationFiled: November 30, 2016Publication date: June 8, 2017Inventors: Alexander H. Cooper, Michael R. Bialas, David M. Taylor, Gregory Scott Tyler, II, Zachary R. Kowalski, Art Z. Kwan, Darshin S. Patel, Asher L. Metchik, Michael J. Popp, Amanda K. Anderson
-
Publication number: 20170095328Abstract: Embodiments of a prosthetic heart valve comprise an annular main body, an atrial cap extending radially outwardly from the atrial end of the main body, and a plurality of ventricular anchors extending outwardly from the ventricular end of the main body. Each ventricular anchor can have a proximal end portion connected to the ventricular end, an intermediate portion extending away from the atrial end and then back toward the atrial so as to define a first bend, and a free distal end portion that extends from the intermediate portion. The distal end portion can comprise a first section, a second section, and a second bend between the first and second sections, the first section extending from the intermediate portion in a direction toward the atrial end and radially away from the main body.Type: ApplicationFiled: December 16, 2016Publication date: April 6, 2017Applicant: Edwards Lifesciences CorporationInventors: Alexander H. Cooper, Matthew A. Peterson, William C. Brunnett
-
Publication number: 20170056169Abstract: Devices, systems and methods are described for implantation of a prosthesis within a lumen or body cavity and delivery systems for delivering the prosthesis to a location for implantation. A delivery system can include a tether connected to a single directional handle knob for release of the prosthesis within the lumen or body cavity and retraction of the tether towards the handle.Type: ApplicationFiled: August 19, 2016Publication date: March 2, 2017Applicant: Edwards Lifesciences CardiAQ LLCInventors: Garrett Dallas Johnson, David Robert Landon, Lindsay Lam, Glen T. Rabito, Alexander H. Cooper
-
Publication number: 20170056171Abstract: Devices, systems and methods are described herein to provide improved steerability for delivering a prosthesis to a body location, for example, for delivering a replacement mitral valve to a native mitral valve location. A delivery component can have a plurality of slots that provide for desired bending of the delivery component, particularly compound bending of the delivery component that can facilitate steering of the delivery component in three dimensions.Type: ApplicationFiled: August 24, 2016Publication date: March 2, 2017Applicant: Edwards Lifesciences CardiAQ LLCInventors: Alexander H. Cooper, David Robert Landon, Julio Cesar Sanchez, Glen T. Rabito, J. Brent Ratz, Arshad Quadri, Kevin M. Stewart, Patrick Chow
-
Patent number: 9532870Abstract: Embodiments of a prosthetic heart valve comprise an annular main body, an atrial cap extending radially outwardly from the atrial end of the main body, and a plurality of ventricular anchors extending outwardly from the ventricular end of the main body. Each ventricular anchor can have a proximal end portion connected to the ventricular end, an intermediate portion extending away from the atrial end and then back toward the atrial so as to define a first bend, and a free distal end portion that extends from the intermediate portion. The distal end portion can comprise a first section, a second section, and a second bend between the first and second sections, the first section extending from the intermediate portion in a direction toward the atrial end and radially away from the main body.Type: GrantFiled: June 4, 2015Date of Patent: January 3, 2017Assignee: Edwards Lifesciences CorporationInventors: Alexander H. Cooper, Matthew A. Peterson, William C. Brunnett
-
Patent number: 9510946Abstract: This disclosure pertains generally to prosthetic devices and related methods for helping to seal native heart valves and prevent or reduce regurgitation therethrough, as well as devices and related methods for implanting such prosthetic devices. In some cases, a spacer having a single anchor can be implanted within a native heart valve. In some cases, a spacer having dual anchors can be implanted within a native heart valve. In some cases, devices can be used to extend the effective length of a native heart valve leaflet.Type: GrantFiled: August 27, 2013Date of Patent: December 6, 2016Assignee: Edwards Lifesciences CorporationInventors: Mark Chau, Travis Oba, Sergio Delgado, Robert C. Taft, Stanton J. Rowe, Alexander H. Cooper
-
Patent number: D815744Type: GrantFiled: June 6, 2016Date of Patent: April 17, 2018Assignee: Edwards Lifesciences CardiAQ LLCInventors: J. Brent Ratz, Luca Pesce, Siddharth Vad, David Robert Landon, Alexander H. Cooper, Glen T. Rabito