Patents by Inventor Alexander L. Watters

Alexander L. Watters has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10245355
    Abstract: Articles, methods of making, and uses for modifying surfaces for liquid repellency are disclosed. The liquid repellant surfaces comprise a surface comprising an anchoring layer. The anchoring layer, which forms an immobilized molecular anchoring layer on the surface, has anchoring molecules, where each anchoring molecule has a head group that is covalently linked to the surface and a functional tail group. The anchoring molecules are crosslinked to each other to form a crosslinked network. The functional tail group has an affinity for a lubricating liquid, which is applied to the treated surface to form a lubricating layer. The anchoring layer and replenishable lubricating liquid are held together by non-covalent attractive forces. Together, these layers form an ultra-repellant slippery surface that repels certain immiscible liquids and prevents adsorption, coagulation, and surface fouling by components contained within.
    Type: Grant
    Filed: July 10, 2014
    Date of Patent: April 2, 2019
    Assignee: President and Fellows of Harvard College
    Inventors: Donald Ingber, Daniel C. Leslie, Michael Super, Alexander L. Watters, Anna Waterhouse
  • Publication number: 20180320157
    Abstract: Described herein are heme-binding compositions and methods relating to their use, e.g. methods of treatment of, for example, sepsis and rhabdomyolysis.
    Type: Application
    Filed: May 1, 2018
    Publication date: November 8, 2018
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Michael SUPER, Alexander L. WATTERS, Philip T. SNELL, Donald E. INGBER
  • Patent number: 9988617
    Abstract: Described herein are heme-binding compositions and methods relating to their use, e.g. methods of treatment of, for example, sepsis and rhabdomyolysis.
    Type: Grant
    Filed: May 21, 2014
    Date of Patent: June 5, 2018
    Assignee: President and Fellows of Harvard College
    Inventors: Michael Super, Alexander L. Watters, Philip T. Snell, Donald E. Ingber
  • Publication number: 20160144079
    Abstract: Articles, methods of making, and uses for modifying surfaces for liquid repellency are disclosed. The liquid repellant surfaces comprise a surface comprising an anchoring layer. The anchoring layer, which forms an immobilized molecular anchoring layer on the surface, has anchoring molecules, where each anchoring molecule has a head group that is covalently linked to the surface and a functional tail group. The anchoring molecules are crosslinked to each other to form a crosslinked network. The functional tail group has an affinity for a lubricating liquid, which is applied to the treated surface to form a lubricating layer. The anchoring layer and replenishable lubricating liquid are held together by non-covalent attractive forces. Together, these layers form an ultra-repellant slippery surface that repels certain immiscible liquids and prevents adsorption, coagulation, and surface fouling by components contained within.
    Type: Application
    Filed: July 10, 2014
    Publication date: May 26, 2016
    Inventors: Donald INGBER, Daniel C. LESLIE, Michael SUPER, Alexander L. WATTERS, Anna WATERHOUSE
  • Publication number: 20160090583
    Abstract: Described herein are heme-binding compositions and methods relating to their use, e.g. methods of treatment of for example, sepsis and rhabdomyolysis.
    Type: Application
    Filed: May 21, 2014
    Publication date: March 31, 2016
    Inventors: Michael SUPER, Alexander L. WATTERS, Philip T. SNELL, Donald E. INGBER
  • Publication number: 20150173883
    Abstract: Articles, methods of making, and uses for modifying surfaces for simultaneously providing repellency and selective binding of desired moieties are disclosed. The repellant surfaces comprise a substrate and a lubricating layer immobilized over the substrate surface having a lubricating liquid having an affinity with the substrate. The substrate and the lubricating liquid are attracted to each other together by non-covalent attractive forces. The repellent surface further includes a binding group extending over the surface of the lubricating layer and the binding group has an affinity with a target moiety. The lubricating layer and the substrate form a slippery or repellent surface configured and arranged for contact with a material that is immiscible with the lubricating liquid and the immiscible material contains the target moiety.
    Type: Application
    Filed: July 12, 2013
    Publication date: June 25, 2015
    Applicant: President and Fellows of Harvard College
    Inventors: Donald Ingber, Michael Super, Daniel C. Leslie, Tohid Didar, Alexander L. Watters, Julia Bellows Berthet, Anna Waterhouse
  • Publication number: 20140342954
    Abstract: Articles, methods of making, and uses for modifying surfaces for liquid repellency are disclosed. The liquid repellant surfaces comprise a surface comprising an anchoring layer. The anchoring layer, which forms an immobilized molecular anchoring layer on the surface, has a head group that is covalently linked to, or adsorbed onto, the surface and a functional group. The functional group of the treated surface has an affinity for a lubricating layer, which is applied to the treated surface. The anchoring layer and replenishable lubricating layer are held together by non-covalent attractive forces. Together, these layers form an ultra-repellant slippery surface that repels certain immiscible liquids and prevents adsorption, coagulation, and surface fouling by components contained within.
    Type: Application
    Filed: January 10, 2013
    Publication date: November 20, 2014
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Donald Ingber, Daniel C. Leslie, Alexander L. Watters, Michael Super, Joanna Aizenberg, Michael Aizenberg, Philseok Kim, Anna Waterhouse