Patents by Inventor Alexander Smith

Alexander Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for Bandwidth Reduction When Streaming Large Format Multi-Frame Image Data
    Publication number: 20190281306
    Abstract: A method, system and computer-usable medium for performing a bandwidth reduction operation, comprising: receiving a plurality of streams of high-density image frames from a respective plurality of monitored devices; storing the plurality of streams of high-density image frames within a monitored content repository; identifying a subset of the plurality of streams of high-density image frames for increased scrutiny; and, presenting a portion of the subset of the plurality of streams of high-density image frames within a scalable viewport.
    Type: Application
    Filed: March 6, 2018
    Publication date: September 12, 2019
    Inventors: Alexander Smith, Kevin Crandell, Mark Price, Natalie McMullen
  • NON-CONTACTING SEAL WITH NON-ABRADABLE COATING
    Publication number: 20190234240
    Abstract: There is provided a non-contacting seal assembly for a gas turbine engine, having a housing that houses a sealing ring; and a counter component cooperating with the sealing ring. The sealing ring and the counter component are rotatable relative to each other about a central axis and define sealing faces circumferentially extending around the central axis. The sealing faces face each other and are spaced apart from each other by a controlled gap. At least one of the sealing faces is coated with a non-abradable material. A method of operating a non-contacting seal assembly is also provided.
    Type: Application
    Filed: January 31, 2018
    Publication date: August 1, 2019
    Inventor: Alexander SMITH
  • Testing pre and post system call exits
    Patent number: 10346293
    Abstract: Embodiments of the invention include systems for testing pre and post system call exits. Aspects include executing a first test case comprises system calls and the first test case initializes a common buffer and stores system call parameters for each of the system calls. A monitoring test case is executed comprising: a pre-exit instruction that is inserted before each system call in the first test case. A post-exit instruction is inserted after each of the system calls in the first test case. Execution of the pre-exit instruction is determined prior to an execution of each system call. A first bit location is set in the common buffer to one, based on determining the pre-exit instruction executes. The system call is executed and execution of the post-exit instruction is determined. A second bit location in the common buffer is set to one based on determining that the post-exit instruction executes.
    Type: Grant
    Filed: October 4, 2017
    Date of Patent: July 9, 2019
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Dominic DeMarco, Christopher Loers, Alexander Smith, Brad D. Stilwell
  • LIGHTNING PROTECTION IN AIRCRAFTS CONSTRUCTED WITH CARBON FIBER REINFORCED PLASTIC
    Publication number: 20190177003
    Abstract: The embodiments described herein provide for lightning protection in aircrafts constructed with Carbon Fiber Reinforced Plastic (CFRP). In one embodiment, the apparatus includes a first Carbon Fiber Reinforced Plastic (CFRP) panel, a second CFRP panel that overlaps with the first CFRP panel in a vertical direction, and a fastener to join the first CFRP panel with the second CFRP panel, the fastener extending in the vertical direction in an area where the first CFRP panel and the second CFRP panel overlap. The apparatus further includes a plurality of electrically conductive pins in each of the first CFRP panel and the second CFRP panel, wherein the pins extend in the vertical direction proximate to the fastener to electrically connect the first CFRP panel and the second CFRP panel in the area where the first CFRP panel and the second CFRP panel overlap.
    Type: Application
    Filed: December 11, 2017
    Publication date: June 13, 2019
    Inventors: Derek R. Tuck, Philipp A. Boettcher, Carson Alexander Smith, David Thomas Misciagna
  • SYNTHESIS OF N-(HETEROARYL)-PYRROLO[3,2-D]PYRIMIDIN-2-AMINES
    Publication number: 20190135820
    Abstract: This invention is in the area of synthesizing pyrimidine-based compounds useful in the treatment of disorders involving abnormal cellular proliferation, including but not limited to tumors and cancers.
    Type: Application
    Filed: December 21, 2018
    Publication date: May 9, 2019
    Applicant: G1 Therapeutics, Inc.
    Inventors: Alexander Smith, Hannah S. White, francis Xavier Tavares, Sergiy Krasutsky, Jian-Xie Chen, Roberta L. Dorrow, Hua Zhong
  • MEASURING AND IMPROVING TEST COVERAGE
    Publication number: 20190102282
    Abstract: Embodiments of the invention include methods and systems for improving test case coverage. Aspects of the invention include executing, by a processor, a first test case, where the first test case includes a plurality of system calls to an operating system. Prior to execution of each system call in the plurality of system calls in the first test case, executing, by the processor, a pre-exit instruction. Responsive to execution of the pre-exit instruction, collecting pre-exit system call data regarding each system call in the plurality of system calls for the first test case. The processor executes a post-exit instruction after completion of each system call in the plurality of system calls and responsive to execution of the post-exit instruction, collects post-exit system call data regarding each system call in the plurality of system calls for the first test case.
    Type: Application
    Filed: November 3, 2017
    Publication date: April 4, 2019
    Inventors: Dominic DeMarco, Christopher Loers, Alexander Smith, Brad D. Stilwell
  • TESTING PRE AND POST SYSTEM CALL EXITS
    Publication number: 20190102285
    Abstract: Embodiments of the invention include systems for testing pre and post system call exits. Aspects include executing a first test case comprises system calls and the first test case initializes a common buffer and stores system call parameters for each of the system calls. A monitoring test case is executed comprising: a pre-exit instruction that is inserted before each system call in the first test case. A post-exit instruction is inserted after each of the system calls in the first test case. Execution of the pre-exit instruction is determined prior to an execution of each system call. A first bit location is set in the common buffer to one, based on determining the pre-exit instruction executes. The system call is executed and execution of the post-exit instruction is determined. A second bit location in the common buffer is set to one based on determining that the post-exit instruction executes.
    Type: Application
    Filed: October 30, 2017
    Publication date: April 4, 2019
    Inventors: Dominic DeMarco, Christopher Loers, Alexander Smith, Brad D. Stilwell
  • MEASURING AND IMPROVING TEST COVERAGE
    Publication number: 20190102281
    Abstract: Embodiments of the invention include methods and systems for improving test case coverage. Aspects of the invention include executing, by a processor, a first test case, where the first test case includes a plurality of system calls to an operating system. Prior to execution of each system call in the plurality of system calls in the first test case, executing, by the processor, a pre-exit instruction. Responsive to execution of the pre-exit instruction, collecting pre-exit system call data regarding each system call in the plurality of system calls for the first test case. The processor executes a post-exit instruction after completion of each system call in the plurality of system calls and responsive to execution of the post-exit instruction, collects post-exit system call data regarding each system call in the plurality of system calls for the first test case.
    Type: Application
    Filed: October 4, 2017
    Publication date: April 4, 2019
    Inventors: Dominic DeMarco, Christopher Loers, Alexander Smith, Brad D. Stilwell
  • TESTING PRE AND POST SYSTEM CALL EXITS
    Publication number: 20190102284
    Abstract: Embodiments of the invention include systems for testing pre and post system call exits. Aspects include executing a first test case comprises system calls and the first test case initializes a common buffer and stores system call parameters for each of the system calls. A monitoring test case is executed comprising: a pre-exit instruction that is inserted before each system call in the first test case. A post-exit instruction is inserted after each of the system calls in the first test case. Execution of the pre-exit instruction is determined prior to an execution of each system call. A first bit location is set in the common buffer to one, based on determining the pre-exit instruction executes. The system call is executed and execution of the post-exit instruction is determined. A second bit location in the common buffer is set to one based on determining that the post-exit instruction executes.
    Type: Application
    Filed: October 4, 2017
    Publication date: April 4, 2019
    Inventors: Dominic DeMarco, Christopher Loers, Alexander Smith, Brad D. Stilwell
  • MODIFIED DNA POLYMERASES
    Publication number: 20190078065
    Abstract: Modified X family DNA polymerases engineered to be capable of incorporating 3?-O-blocked nucleotide 5?-triphosphates during template-independent polynucleotide synthesis, and methods for synthesizing polynucleotides using said modified X family DNA polymerases.
    Type: Application
    Filed: September 7, 2018
    Publication date: March 14, 2019
    Inventors: Thomas Baiga, Michael Anderson Burley, Alexander Smith
  • POLYMERASE-MEDIATED, TEMPLATE-INDEPENDENT POLYNUCLEOTIDE SYNTHESIS
    Publication number: 20190078126
    Abstract: Methods for de novo synthesis of polynucleotides in which 3?-O-reversibly blocked nucleotides are attached to a solid support in the presence of an X family DNA polymerase and in the absence of a nucleic acid template.
    Type: Application
    Filed: September 7, 2018
    Publication date: March 14, 2019
    Inventors: Thomas Baiga, Michael Anderson Burley, Alexander Smith
  • Kinetic energy harvesting methods and apparatus
    Patent number: 10153683
    Abstract: A system, method, and apparatus for kinetic energy harvesting are disclosed. An example kinetic energy harvesting apparatus includes a tubular-shaped magnet housing and an end-cap magnet configured to connect to an end of the magnet housing. The apparatus also includes a wire coil configured to be connected to the magnet housing. The apparatus further includes a central magnet configured to be located within the magnet housing and suspended via the end-cap magnet.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: December 11, 2018
    Assignee: Stryde Technologies Inc.
    Inventors: Tejas Attreya Shastry, Michael Geier, Alexander Smith
  • RESIN INFUSION PROCESS FOR MANUFACTURING FIBER-REINFORCED COMPOSITES
    Publication number: 20180272628
    Abstract: A resin infusion method that incorporates a melt-on-demand approach. The method includes: (a) providing a curable resin composition in the form of a block of frozen resin (20); (b) coupling the block of frozen resin (20) to an inlet port of a heated extruder (22), which comprises at least one rotating screw (24) housed within a heated barrel (25); (c) progressively melting the block of frozen resin (20) at the inlet port and concurrently feeding the melt resin through the heated barrel (25) to produce a liquid resin having a viscosity suitable for resin infusion; (d) continuously feeding the liquid resin exiting from the extruder to a mold, which contains a fibrous preform; and (e) introducing the liquid resin into the fibrous preform, wherein the block of frozen resin (20) provides an amount of resin composition sufficient for infusing the entire fibrous preform.
    Type: Application
    Filed: December 15, 2016
    Publication date: September 27, 2018
    Inventors: Jonathan Edward MEEGAN, Michael Alexander SMITH, Scott Alfred ROGERS, Jeffrey Jon ROSE
  • COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES
    Publication number: 20180251457
    Abstract: Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with angiogenesis, for example, ocular conditions. Formulations for increased solubility are disclosed. Combination therapy with antibodies and PK/PD data are also disclosed.
    Type: Application
    Filed: May 2, 2018
    Publication date: September 6, 2018
    Inventors: Kevin Peters, Robert Shalwitz, John Janusz, Alexander Smith
  • COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES
    Publication number: 20180237429
    Abstract: Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with angiogenesis, for example, ocular conditions. Formulations for increased solubility are disclosed. Combination therapy with antibodies and PK/PD data are also disclosed.
    Type: Application
    Filed: April 20, 2018
    Publication date: August 23, 2018
    Inventors: Kevin Peters, Robert Shalwitz, John Janusz, Alexander Smith
  • COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES
    Publication number: 20180237430
    Abstract: Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with angiogenesis, for example, ocular conditions. Formulations for increased solubility are disclosed. Combination therapy with antibodies and PK/PD data are also disclosed.
    Type: Application
    Filed: April 20, 2018
    Publication date: August 23, 2018
    Inventors: Kevin Peters, Robert Shalwitz, John Janusz, Alexander Smith
  • COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES
    Publication number: 20180237431
    Abstract: Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with angiogenesis, for example, ocular conditions. Formulations for increased solubility are disclosed. Combination therapy with antibodies and PK/PD data are also disclosed.
    Type: Application
    Filed: April 20, 2018
    Publication date: August 23, 2018
    Inventors: Kevin Peters, Robert Shalwitz, John Janusz, Alexander Smith
  • METHODS AND SYSTEMS FOR EVALUATION AND EXECUTION OF A CONTROL STRATEGY ALGORITHM
    Publication number: 20180204235
    Abstract: Disclosed herein are systems and methods that automatically identify instances where a site of a business merchant being analyzed for a test event is involved in another test event affecting a similar category of item that is being analyzed during a same time frame. The algorithm executed to automatically identify concurring events occurring at the same site calculates each event's date range, marks events as overlapping based on date range and primary category of items affected, and then determines concurring items in concurring events. The concurring events identified are accounted for in forecasting a lift over a baseline forecast in response to a promotion to estimate the effects of each promotion independently.
    Type: Application
    Filed: January 19, 2017
    Publication date: July 19, 2018
    Inventors: Briana WHELAN, Alexander Smith, Adam BEATON, Robert ALEXANDER, II, Elizabeth LIANG, Sean WALSH, Dennis TING
  • Compositions and Methods for Treating Anemia
    Publication number: 20180092892
    Abstract: Provided herein are specific doses of, and dosing regimens for, using a HIF prolyl hydroxylase inhibitor in treating or preventing anemia, such as anemia secondary to or associated with chronic kidney disease, anemia secondary to or associated with non-dialysis dependent chronic kidney disease anemia associated with or resulting from chemotherapy, or anemia associated with AIDS.
    Type: Application
    Filed: March 31, 2016
    Publication date: April 5, 2018
    Applicant: Akebia Therapeutics, Inc.
    Inventors: Alexander Smith, Gurudatt Ajay Chandorkar, Ene Ikpong Ette, Bradley John Maroni, Charlotte Suzanne Hartman, Ramin Farzaneh-Far, Jula Kem Inrig
  • VAGINAL STENTS, VAGINAL DILATORS, AND METHODS OF FABRICATING THE SAME
    Publication number: 20180071502
    Abstract: One aspect of the invention provides a vaginal stent system including: an inflatable vaginal stent and a removable handle. The inflatable vaginal stent include includes: an elastomeric exterior wall and a first fitting located at a base of the inflatable vaginal stent. The removable handle is adapted and configured for insertion, inflation, and removal of the inflatable vaginal stent from a subject's vagina. The removable handle includes a second fitting complementary to the first fitting and adapted and configure to form substantially fluid tight coupling when the handle is coupled to the inflatable vaginal stent. Another aspect of the invention provides a method of fabricating a customized vaginal stent or dilator. The method includes: generating a 3D model of a vaginal stent or dilator; and controlling a 3D printer to fabricate a vaginal stent or dilator according to the 3D model.
    Type: Application
    Filed: April 4, 2016
    Publication date: March 15, 2018
    Applicant: Baylor College of Medicine
    Inventors: Julie HAKIM, Jennifer Elizabeth DIETRICH, Peter Alexander SMITH, Cara BUSKMILLER