Patents by Inventor Alexander V. Kabanov

Alexander V. Kabanov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOLOGICAL AGENT-EXOSOME COMPOSITIONS AND USES THEREOF
    Publication number: 20220409535
    Abstract: The present invention relates to compositions comprising exosomes and biological agents and methods of using the compositions for the delivery of biological agents to cells and to subjects.
    Type: Application
    Filed: August 23, 2022
    Publication date: December 29, 2022
    Inventors: Elena V. Batrakova, Alexander V. Kabanov, Marina Sokolsky, Matthew J. Haney, Dongfen Yuan, Myung Soo Kim
  • Polyelectrolyte complexes for delivery of agents to the CNS
    Patent number: 11484574
    Abstract: The present invention relates to compositions and methods for the delivery of agents to a subject, particularly to the central nervous system (CNS).
    Type: Grant
    Filed: February 1, 2017
    Date of Patent: November 1, 2022
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Alexander V. Kabanov, Yuhang Jiang, Xing Yi
  • Biological agent-exosome compositions and uses thereof
    Patent number: 11458097
    Abstract: The present invention relates to compositions comprising exosomes and biological agents and methods of using the compositions for the delivery of biological agents to cells and to subjects.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: October 4, 2022
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Elena V. Batrakova, Alexander V. Kabanov, Marina Sokolsky, Matthew J. Haney, Dongfen Yuan, Myung Soo Kim
  • BIOLOGICAL AGENT-EXOSOME COMPOSITIONS AND USES THEREOF
    Publication number: 20200297631
    Abstract: The present invention relates to compositions comprising exosomes and biological agents and methods of using the compositions for the delivery of biological agents to cells and to subjects.
    Type: Application
    Filed: March 30, 2017
    Publication date: September 24, 2020
    Inventors: Elena V. Batrakova, Alexander V. Kabanov, Marina Sokolsky, Matthew J. Haney, Dong-fen Yuan, Myung Soo Kim
  • POLYELECTROLYTE COMPLEXES FOR DELIVERY OF AGENTS TO THE CNS
    Publication number: 20190111109
    Abstract: The present invention relates to compositions and methods for the delivery of agents to a subject, particularly to the central nervous system (CNS).
    Type: Application
    Filed: February 1, 2017
    Publication date: April 18, 2019
    Inventors: Alexander V. Kabanov, Yuhang Jiang, Xing Yi
  • Magnetic Nanoparticle-Polymer Complexes and uses Thereof
    Publication number: 20190054186
    Abstract: The present invention relates to magnetic nanoparticles coated with block copolymers. The invention further relates to methods of increasing cellular uptake of magnetic nanoparticles and use of the coated magnetic particles to selectively kill cancer cells, treat cancer, detect cancer, and for biomedical imaging.
    Type: Application
    Filed: March 31, 2017
    Publication date: February 21, 2019
    Inventors: Alexander V. Kabanov, Marina Sokolsky, Philise N. Williams
  • Compositions and methods for the treatment of cancer
    Patent number: 10022325
    Abstract: The present invention provides compositions and methods for the treatment of cancer are provided.
    Type: Grant
    Filed: March 4, 2013
    Date of Patent: July 17, 2018
    Assignee: Board of Regents of the University of Nebraska
    Inventors: Alexander V. Kabanov, Daria Y. Alakhova, Yi Zhao
  • Protein-poly(2-oxazoline) conjugates for enhanced cellular delivery and transport across biological barriers
    Patent number: 9974866
    Abstract: The present invention provides polymer-polypeptide conjugates comprising a poly(2-oxazoline) amphiphilic block copolymer linked to a polypeptide and methods of use thereof.
    Type: Grant
    Filed: April 7, 2011
    Date of Patent: May 22, 2018
    Assignee: Board of Regents of the University of Nebraska
    Inventors: Alexander V. Kabanov, Jing Tong
  • Drug delivery compositions and methods
    Patent number: 9498533
    Abstract: The present invention provides compositions and methods for the delivery of therapeutics to a cell or subject.
    Type: Grant
    Filed: April 4, 2012
    Date of Patent: November 22, 2016
    Assignee: Board of Regents of the University of Nebraska
    Inventors: Tatiana K. Bronich, Alexander V. Kabanov, Jong Oh Kim
  • Polymeric delivery systems for active agents
    Patent number: 9402908
    Abstract: The present invention provides polymer aggregates as delivery vehicles for therapeutics and diagnostics. The present invention additionally provides methods of synthesis and uses for such aggregates.
    Type: Grant
    Filed: December 31, 2013
    Date of Patent: August 2, 2016
    Inventors: Alexander V. Kabanov, Rainer Jordan, Robert Luxenhofer
  • Water soluble fullerene formulations and methods of use thereof
    Patent number: 9233164
    Abstract: The present invention provides water soluble fullerene formulations and methods of use thereof.
    Type: Grant
    Filed: January 13, 2012
    Date of Patent: January 12, 2016
    Assignee: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
    Inventors: Alexander V. Kabanov, Jing Tong
  • DELIVERY OF BIOTHERAPEUTICS TO THE BRAIN
    Publication number: 20150306181
    Abstract: Compositions and methods for delivering therapeutic compounds to the brain are provided.
    Type: Application
    Filed: February 6, 2013
    Publication date: October 29, 2015
    Inventors: Xiang Yi, Alexander V. Kabanov, William Banks
  • SMALL MAGNETITE THERAPEUTICS AND METHODS OF USE THEREOF
    Publication number: 20150125401
    Abstract: The present invention provides compositions and methods for the delivery of therapeutics to a cell or subject.
    Type: Application
    Filed: April 15, 2013
    Publication date: May 7, 2015
    Inventors: Howard E. Gendelman, Alexander V. Kabanov, Xin-Ming Liu, Richey M. Davis, Judy Riffle
  • TUNABLE MULTIMODAL NANOPARTICLES AND METHODS OF USE THEREOF
    Publication number: 20150079007
    Abstract: Tunable nanoparticles and methods of use thereof are provided. In accordance with the instant invention, tunable nanoparticles comprising a metal nanoparticle core (e.g., a paramagnetic particle (e.g., USPIO) or a quantum dot) and a polymer linked to a metal binding moiety are provided. The polymer of the nanoparticle is bound to the metal nanoparticle core by the metal binding moiety and coats the metal nanoparticle core. In a particular embodiment, the metal binding moiety comprises bisphosphonate, pyrophosphate, or a derivative thereof. In a particular embodiment, the polymer is a hydrophilic polymer, an amphiphilic block copolymer or an ionic block copolymer.
    Type: Application
    Filed: April 22, 2013
    Publication date: March 19, 2015
    Applicant: Board of Regents of the University of Nebraska
    Inventors: Xin-Ming Liu, Alexander V. Kabanov, Howard E. Gendelman
  • POLYMERIC DELIVERY SYSTEMS FOR ACTIVE AGENTS
    Publication number: 20140170197
    Abstract: The present invention provides polymer aggregates as delivery vehicles for therapeutics and diagnostics. The present invention additionally provides methods of synthesis and uses for such aggregates.
    Type: Application
    Filed: December 31, 2013
    Publication date: June 19, 2014
    Applicants: UNIVERSITY OF NEBRASKA MEDICAL CENTER, TECHNISCHE UNIVERSITAT MUNCHEN
    Inventors: Alexander V. Kabanov, Rainer Jordan, Robert Luxenhofer
  • Nanozyme Compositions and Methods of Synthesis and Use Thereof
    Publication number: 20140120075
    Abstract: Nanozymes and methods of use and synthesis thereof are provided.
    Type: Application
    Filed: May 24, 2012
    Publication date: May 1, 2014
    Applicant: Board of Regents of the University of Nebraska
    Inventors: Alexander V. Kabanov, Davika Soundara Manickam, Anna M. Brynskikh
  • Drug Delivery Compositions and Methods
    Publication number: 20140039068
    Abstract: The present invention provides compositions and methods for the delivery of therapeutics to a cell or subject.
    Type: Application
    Filed: April 4, 2012
    Publication date: February 6, 2014
    Applicant: Board of Regents of the University of Nebraska
    Inventors: Tatiana K. Bronich, Alexander V. Kabanov, Jong Oh Kim
  • Water Soluble Fullerene Formulations and Methods of Use Thereof
    Publication number: 20130323188
    Abstract: The present invention provides water soluble fullerene formulations and methods of use thereof.
    Type: Application
    Filed: January 13, 2012
    Publication date: December 5, 2013
    Applicant: Board of the Regents of the University of Nebraska
    Inventors: Alexander V. Kabanov, Jing Tong
  • Amphiphilic polymer-protein conjugates and methods of use thereof
    Patent number: 8535656
    Abstract: Compositions and methods for transporting biologically active proteins and polypeptides, particularly across the blood-brain barrier, are provided.
    Type: Grant
    Filed: March 9, 2012
    Date of Patent: September 17, 2013
    Assignee: Board of Regents of the University of Nebraska
    Inventors: Alexander V. Kabanov, Xiang Yi, Sarguel V. Vinogradov, William A. Banks
  • Compositions and Methods for the Delivery of Therapeutics
    Publication number: 20130236553
    Abstract: The present invention provides compositions and methods for the delivery of therapeutics to a cell or subject.
    Type: Application
    Filed: November 2, 2011
    Publication date: September 12, 2013
    Applicant: Board of Regents of the University of Nebraska
    Inventors: Howard E. Gendelman, Alexander V. Kabanov, Xin-Ming Liu