Abstract: The invention relates to the use of a pharmaceutical composition containing nicotinamide (NAM) and/or pyruvate as a neuroprotective medicament or gene therapy in the treatment of neurodegenerative disorders, in particular axon degeneration of neuronal tissue in ocular-related neurodegeneration diseases including glaucoma.

Abstract: A media management system that generates a plurality of values associated with a promotion impact measure for each of the promotional campaigns based on historical data that is acquired and an expected audience. Inventory unit needs are determined for each of the promotional campaigns that corresponds to a promotion inventory utilization of a plurality of inventory utilization types, based on at least the generated plurality of values. The determined inventory units for each of the promotional campaigns are utilized to dynamically allocate inventory from a defined amount of inventory units among each inventory utilization types to meet a plurality of defined parameters for the defined amount of inventory units for one or more specified durations until an end of the upcoming time-frame.

Abstract: In an example implementation according to aspects of the present disclosure, a system comprising a camera, a plurality of displays and a processor. The processor receives a series of images, from the camera, corresponding to a physical environment, wherein the series of images include the plurality of displays. The processor identifies a fiducial mark within the series of images corresponding to a display. The processor determines a three-dimensional space based on a camera position based on the series of images. The processor determines a location within the three-dimensional space corresponding to the one of the plurality of displays. The processor creates a geospatial relationship between the location and the camera within the three-dimensional space. The processor correlates the geospatial relationship to a display configuration screen. The processor creates a pointing device path in the display configuration screen corresponding to the geospatial relationship.

Abstract: A catheter structure, such as a balloon catheter (30), guidewire, or the like, with markings (32) perceptible outside of the vasculature is for use in determining at a location external to the body the position of the catheter structure relative to a treatment area. Related kits are also disclosed.

Abstract: Systems and methods for automatically removing and replacing outdated compute resources in a cluster. The systems and methods include a configurable monitoring system that is configured to detect outdated compute resources and trigger a cycling process to automatically replace the detected outdated compute resources with new compute resources. The disclosed systems and methods safely rotate a group of compute resources by identifying and detaching outdated compute resources, waiting until the outdated compute resources have been drained of pending jobs scheduled on these resources, waiting until replacement compute resources have started and then cordoning, draining, deleting and terminating the outdated compute resources.

Abstract: The present invention relates to compounds of Formula (I), wherein R1, R2, R3, R4x, R4y, m, n and G are as defined herein. The invention further relates to herbicidal compositions which comprise a compound of Formula (I), to their use for controlling weeds, in particular in crops of useful plants.

Abstract: A computerized method is shown and includes receiving one or more lists of identifiers, generating a batch query from the one or more lists of identifiers, querying one or more data stores using the batch query, generating one or more response packets including results from querying using the batch query, and transmitting a first response packet to a first edge device. Generating the batch query may be performed by merging a plurality of lists of identifiers to form a merged list, and removing duplicate identifiers from the merged list. Further, the first response packet may be generated for the first edge device and includes enrichment data corresponding to identifiers transmitted by the first edge device. Additionally, may be the first response packet is generated for a plurality of edge devices including the first edge device and includes enrichment data corresponding to identifiers transmitted by the plurality of edge device.

Abstract: A keyboard includes a processing resource and a memory resource storing machine-readable instructions to cause the processing resource to communicate, in response to the keyboard being in a computing device input mode, with a computing device connected to the keyboard, and communicate, in response to the keyboard being in a mobile device input mode, with a mobile device connected to the keyboard.

Abstract: The present invention relates to compounds of Formula (I), wherein R1, R2, R3, R4 and G are as defined herein. The invention further relates to herbicidal compositions which comprise a compound of Formula (I), to their use for controlling weeds, in particular in crops of useful plants.

Abstract: A media management system that generates expected audience of a promo schedule for each promotional campaign planned for an upcoming time-frame, acquires historical data for the promotional campaigns for the time-frame, and generates a plurality of values associated with a promotion impact measure for each of the promotional campaigns based on the acquired historical data and the expected audience. Inventory unit needs are determined for each of the promotional campaigns that corresponds to a promotion inventory utilization of a plurality of inventory utilization types, based on at least the generated plurality of values. The determined inventory units for each of the promotional campaigns are utilized to dynamically allocate inventory from a defined amount of inventory units among each inventory utilization types to meet a plurality of defined parameters for the defined amount of inventory units for one or more specified durations until an end of the upcoming time-frame.

Abstract: According to examples, an apparatus may include a processor that may access an assignment of a capability to a hardware port such as a Universal Serial Bus (“USB”) port. The apparatus may virtualize a USB port, assign capabilities to the virtual USB port, and provide electrical communication via the USB port subject to the assigned capabilities. The electrical communication may include power delivered via the USB port, or data communicated via the USB port.

Abstract: The present invention relates to compounds of Formula (I), (I) wherein R1, R2, R3 and R4 are as defined herein. The invention further relates to herbicidal compositions which comprise a compound of Formula (I), to their use for controlling weeds, in particular in crops of useful plants.

Abstract: In an example implementation according to aspects of the present disclosure, a mouse system comprising a plurality of temperature sensors, a thermoelectric device, and a processor. The processor receives a first input and second input from a first temperature sensor and second temperature sensor respectively. The first temperature sensor is in proximity to a users fingers, and the second temperature sensor is in proximity to a users palm. The processor activates the thermoelectric device based on the received first and second inputs. The processor receives a feedback from a user response and the feedback, the first input and second input are provided as input to a machine learning model.

Abstract: A process is presented for creating 3D sculptures using a 3D printer. The 3D sculptures form a foreground for a 2D base image also applied by the 3D printer. The process involves using a 3D printer to apply colors and/or images like a conventional 2D printer while the 3D product is being created. A 2D base design is combined with a 3D sculpture design to create an integral “canvas” which faces outward from the base and presents a 3D image emerging from a 2D background. The completed “canvas” can then be attached to an apparel item, such as a hat, or an accessory item, such as a bag, using magnets or other conventional mechanical attachment means.

Abstract: The invention relates to the use of a pharmaceutical composition containing nicotinamide (NAM) and/or pyruvate as a neuroprotective medicament or gene therapy in the treatment of neurodegenerative disorders, in particular axon degeneration of neuronal tissue in ocular-related neurodegeneration diseases including glaucoma.

Abstract: Provided are methods and systems for draining underground soil moisture and water at a site. The methods and systems utilize a secured pipe system having a leading edge to drill the system into the earth, and perforations along portions of the surface of the system to receive accumulated water from underground and deliver it to the surface. A pipe cradle guide as provided is useful in the installation of the system. To also inject soil stabilizing materials (a mixture of sand and gel) into the earth using the secured pipe system, a removable canister is coupled to the distal end of the pipe system, and using water pressure the soil stabilizing materials are delivered to the soil by means of the secured pipe system.

Abstract: A system, method, and apparatus for modifying the state of headphones is disclosed. For example, a system may include a pair of headphones in a first state and a headphone assembly physically connecting the pair of headphones. The system may include a biometric sensor located on the headphone assembly. The system may also include a local authenticator located in the pair of headphones to switch the headphones to a second state in response to a user providing authentication to the pair of headphones by interacting with the biometric sensor.

Abstract: Systems and methods are disclosed for implementing a low-latency data stream monitoring system. The data stream monitoring system may obtain raw data from a data source as soon after the data is generated, and may classify the data according to different topics. The topics may be published in a publish-subscribe messaging model, and data enrichment systems may subscribe to the topics to receive data for enrichment. The data enrichment systems may supplement or replace the raw data with additional information, and may further classify or reclassify the enriched data into different topics. The enriched data may then be published to an alert generation system, which may apply various criteria to the enriched data to determine that alerts should be generated, generate the alerts, and publish or transmit the alerts to client devices. Individual data streams, topics, enrichments, criteria, and alarms may be added, removed, or modified as required.