Abstract: Provided herein are antibodies that bind to the alpha subunit of an IL-7 receptor (IL-7R?). Also provided are uses of these antibodies in therapeutic applications, such as treatment of inflammatory diseases. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain regions of the antibodies, and vectors comprising the polynucleotides.

Abstract: The disclosure relates to systems and methods for displaying three-dimensional (3D) content in a spatial 3D environment. The systems and methods can include receiving a request from web domain to display 3D content of certain dimensions at a location within the spatial 3D environment, identifying whether the placement is within an authorized portion of the spatial 3D environment, expanding the authorized portion of the 3D spatial environment to display the 3D content based on a user authorization to resize the authorized portion, and displaying the 3D content.

Abstract: The disclosure relates to systems and methods for displaying three-dimensional (3D) content in a spatial 3D environment. The systems and methods can include receiving a request from web domain to display 3D content of certain dimensions at a location within the spatial 3D environment, identifying whether the placement is within an authorized portion of the spatial 3D environment, expanding the authorized portion of the 3D spatial environment to display the 3D content based on a user authorization to resize the authorized portion, and displaying the 3D content.

Abstract: Various embodiments of an apparatus, methods, systems and computer program products described herein are directed to an Interaction Engine. The Interaction Engine generates, within a unified three-dimensional (3D) coordinate space: (i) a 3D virtual medical model positioned according to a model pose and (ii) at least one 3D virtual slice that corresponds with a view of respective slice layer from a plurality of slice layers associated with the 3D virtual medical model. The Interaction Engine renders an Augmented Reality (AR) display that includes concurrent display of the 3D virtual medical model and the 3D virtual slice(s). The Interaction Engine detects one or more physical gestures associated with the user and the physical instrument. The Interaction Engine identifies at least one interaction associated with the detected physical gestures and modifies the AR display according to the identified interaction.

Abstract: Various embodiments of an apparatus, methods, systems and computer program products described herein are directed to an Interaction Engine. The Interaction Engine generates, within a unified three-dimensional (3D) coordinate space: (i) a 3D virtual medical model positioned according to a model pose and (ii) at least one 3D virtual slice that corresponds with a view of respective slice layer from a plurality of slice layers associated with the 3D virtual medical model. The Interaction Engine renders an Augmented Reality (AR) display that includes concurrent display of the 3D virtual medical model and the 3D virtual slice(s). The Interaction Engine detects one or more physical gestures associated with the user and the physical instrument. The Interaction Engine identifies at least one interaction associated with the detected physical gestures and modifies the AR display according to the identified interaction.

Abstract: A method for monitoring performance of an application system which is distributed across a plurality of network connected nodes, comprising: generating a hierarchical model for the application system, the hierarchical model having a plurality of levels, each level including components of a span specific to that level; mapping the application system onto the hierarchical model according to a network topology of the application system; monitoring network traffic between the plurality of network connected nodes of the application system to gather network traffic data; assembling the network traffic data into application messages; correlating the application messages into sets of one or more application messages that are causally associated in accordance with the hierarchical model, wherein the sets of causally associated application messages constitute transactions corresponding to a lowest level of the hierarchical model; and, generating records of individual transactions occurring within the application system

Abstract: The disclosure relates to systems and methods for displaying three-dimensional (3D) content in a spatial 3D environment. The systems and methods can include receiving a request from web domain to display 3D content of certain dimensions at a location within the spatial 3D environment, identifying whether the placement is within an authorized portion of the spatial 3D environment, expanding the authorized portion of the 3D spatial environment to display the 3D content based on a user authorization to resize the authorized portion, and displaying the 3D content.

Abstract: The present invention provides pharmaceutical compounds and methods for preventing, ameliorating, or treating a mitochondrial disease by administering such compounds to a subject in need thereof. In some cases, the subject suffers from a mitochondrial disease or is predisposed to having a mitochondrial disease. The mitochondrial disease includes those associated with impairments to mitochondrial oxidative phosphorylation that can lead to vision loss or blindness.

Abstract: A method for monitoring performance of an application system which is distributed across a plurality of network connected nodes, comprising: generating a hierarchical model for the application system, the hierarchical model having a plurality of levels, each level including components of a span specific to that level; mapping the application system onto the hierarchical model according to a network topology of the application system; monitoring network traffic between the plurality of network connected nodes of the application system to gather network traffic data; assembling the network traffic data into application messages; correlating the application messages into sets of one or more application messages that are causally associated in accordance with the hierarchical model, wherein the sets of causally associated application messages constitute transactions corresponding to a lowest level of the hierarchical model; and, generating records of individual transactions occurring within the application system

Abstract: The present invention provides pharmaceutical compounds and methods for preventing, ameliorating, or treating a mitochondrial disease by administering such compounds to a subject in need thereof. In some cases, the subject suffers from a mitochondrial disease or is predisposed to having a mitochondrial disease. The mitochondrial disease includes those associated with impairments to mitochondrial oxidative phosphorylation that can lead to vision loss or blindness.

Abstract: “Let the Bullet fly for a while, Let the Phone Fly, Phonefly!” The carrier of the Phonefly xPhone is the disclub golf having the cam lock. The next generation Phonefly xPhone is the dual-Phone-Watch pair having the ultra-long flying capabilities with cam lock and the remote monitoring/watching capability. Due to the disclub golfrisbee, golf disc, having no impact force as the golf ball does, the disclub golf having the cam lock becomes the practical vehicle to carry the Phonefly xPhone to far end and monitoring with Watch. The complete set of Phonefly xPhone ecosystem includes the disclub, golfrisbee/disc/golfring, dual-phone-watch, disclub trolley, disclub retriever, disc-ball hybrid flagpole, disc -ball hybrid harvest machine and disc-ball hybrid vending machine, etc. The Phonefly xPhone is the pairs of smart phone sPhone, smart watch, game monitor and game controller, combining with disclub golf to have the extra dimension of freedom to have the remote access, control and monitoring of far end activities.

Abstract: “Let the Bullet fly for a while, Let the Phone Fly, Phonefly!” The carrier of the Phonefly xPhone is the disclub golf. The next generation Phonefly xPhone is the dual-Phone-Watch pair having the flying capabilities and remote monitoring/watching capability. Due to the disclub golfrisbee, golf disc, having no impact force as the golf ball does, the disclub golf becomes the practical vehicle to carry the Phonefly xPhone to far end and monitoring with Watch. The complete set of Phonefly xPhone ecosystem includes the disclub, golfrisbee/disc/golfring, dual-phone-watch, disclub trolley, disclub retriever, disc-ball hybrid flagpole, disc-ball hybrid harvest machine and disc-ball hybrid vending machine, etc. The Phonefly xPhone is the pairs of smart phone sPhone, smart watch, game monitor and game controller, combining with disclub golf to have the extra dimension of freedom to have the remote access, control and monitoring of far end activities. It bridges the virtual world with the reality world.

Abstract: A method for executing an application, comprising: receiving data associated with the application; storing the data in a data buffer in a data store; selecting one or more module instances to define a function of the application, each module instance for independently performing a respective aspect of the function, each module instance independently accessing the data buffer directly from the data store to process data contained therein to perform its aspect of the function; and, using a processor, initiating operation of the one or more module instances in accordance with a schedule defined by one or more routing rules, the one or more routing rules for routing a pointer to the data, as stored in the data buffer, between the one or more module instances to thereby perform the function without passing the data itself between the one or more module instances.

Abstract: For Scalable iPindow of iPhome & Scalable Smart Window of Smart Home, the Wireless Window 5R System W5RS is constituted of smart Multimedia Window, smart Electrochromic Window and smart Solar Window, etc. The smart Solar Window harvests solar energy to be electric energy to provide power to smart Multimedia Window and smart Electrochromic Window, etc. “W5RS” is the next generation standard. “5S” represents “Smart Solar Supply Silicon System”. “W5” represents “Wireless Wireline Weave Wishful Window”. “5R” represents “Recycling Resonant Resynchronization Rectifying Regulator”. “W5RS” is the killer application and “5R” is the killer core technology. For the WPC Qi and A4WP wireless power supply standards, the novel 5R can have the AC/DC power efficiency 95% which is the highest.

Abstract: A method for monitoring performance of an application system which is distributed across a plurality of network connected nodes, comprising: generating a hierarchical model for the application system, the hierarchical model having a plurality of levels, each level including components of a span specific to that level; mapping the application system onto the hierarchical model according to a network topology of the application system; monitoring network traffic between the plurality of network connected nodes of the application system to gather network traffic data; assembling the network traffic data into application messages; correlating the application messages into sets of one or more application messages that are causally associated in accordance with the hierarchical model, wherein the sets of causally associated application messages constitute transactions corresponding to a lowest level of the hierarchical model; and, generating records of individual transactions occurring within the application system