Abstract: The present invention is directed to a new fluoro-pyridinone hydroxamic acid phosphates and boronates of Formulae I, II and III wherein Q is selected from the group consisting of —P(O)(OH)2, —P(O)(OH)(O?M+), —P(O)(O?M+)2 and —P(O)(O?)2M2+; M+ at each occurrence is a pharmaceutically acceptable monovalent cation; and M2+ is a pharmaceutically acceptable divalent cation and their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.

Abstract: In response to failure of an initial value transfer in a computer system, user input can be provided to choose between multiple alternative fallback options to change a value transfer processing plan. As another example, in response to failure of a single initial value transfer specified in a processing plan, a processing plan modification routine can include revising the processing plan to incorporate a fallback option allowed in processing plan rules in the computer system, where the fallback option can include multiple scheduled fallback value transfers that are each for amounts that are less than an amount of the initial value transfer. Additionally, a user interface control can be designed to receive user input to indicate selection of a value transfer option from a plurality of available value transfer options with different amounts of automation or interactivity for value transfers made according to the value transfer options.