Patents by Inventor Allan Smith

Allan Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Segmented Direct Drive Motor For Use in a Computed Tomography System
    Publication number: 20170214279
    Abstract: The present approach includes, in one implementation, a direct drive motor for use in a CT gantry and having a segmented motor stator assembly. The stator segments are connected in series. The stator segments are not independently operable and are instead connected in series to, and operated by, a single frequency controller.
    Type: Application
    Filed: January 27, 2016
    Publication date: July 27, 2017
    Inventors: Chad Allan Smith, James Charles Bartelsen
  • Method and apparatus for table-gantry alignment in an imaging system
    Patent number: 9687203
    Abstract: Method and apparatus are provided for aligning a cradle supported by a table in an imaging system with a gantry scan plane in a bore of the gantry. More particularly, various embodiments provide a laser alignment structure having at least two alignment apertures arranged along an axis of the bore, and an adjustment device configured to adjust a position of the laser so that the laser beam is aligned with the alignment apertures. Highly accurate alignment of the cradle to the gantry scan plane is achieved by utilizing this apparatus in tandem with an imaging-based alignment analysis method.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: June 27, 2017
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Brandon Allan Smith, Ariel Friedlander
  • Pyrazolopyrimidine compounds
    Patent number: 9662336
    Abstract: Compounds of formula (I) and salts thereof: wherein R1 is n-C1-6alkyl or C1-2alkoxyC1-2alkyl-, R2 is halo, OH or C1-3alkyl, m is an integer having a value of 4, 5, 6 or 7, n is an integer having a value of 0, 1, 2 or 3, and p is an integer having a value of 0, 1 or 2, are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions, for example allergic rhinitis and asthma, infectious diseases and cancer, and may also be useful as vaccine adjuvants.
    Type: Grant
    Filed: October 1, 2015
    Date of Patent: May 30, 2017
    Assignee: GlaxoSmithKline LLC
    Inventors: Diane Mary Coe, Stephen Allan Smith
  • N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamides and N-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamides and their therapeutic use
    Patent number: 9624167
    Abstract: The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain substituted N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and N-(4-hydroxy-4-methyl -cyclohexyl)-4-(2-pyridyl)benzenesulfonamide compounds (collectively referred to herein as HMC compounds) that are useful, for example, in the treatment of disorders (e.g.
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: April 18, 2017
    Assignee: PIMCO 2664 Limited
    Inventors: Lisa Patel, Stephen Allan Smith, Iain Robert Greig, Samuel Cameron Williams
  • NOVEL COMPOUNDS
    Publication number: 20170080085
    Abstract: Compounds of formula (I) and salts thereof: wherein R1 is n-C4-6alkyl or C1-2alkoxyC1-2alkyl-; R2 is hydrogen or methyl; each R3 is hydroxy, halo or n-C1-3alkyl; m is an integer having a value of 2 to 4; n is an integer having a value of 0 to 3; and p is an integer having a value of 0 to 2, are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions, for example allergic rhinitis and asthma, infectious diseases and cancer, and may also be useful as vaccine adjuvants.
    Type: Application
    Filed: December 6, 2016
    Publication date: March 23, 2017
    Inventors: Diane Mary COE, Stephen Allan SMITH
  • PYRROLO[3,2-D]PYRIMIDINE DERIVATIVES AS INDUCERS OF HUMAN INTERFERON
    Publication number: 20170057963
    Abstract: Compounds of formula (I) and salts thereof: wherein R1 is hydrogen, methyl or —(CH2)2OR3, R2 is methyl or —(CH2)2OR4, or R1 and R2, together with the nitrogen atom to which they are attached, are linked to form a 5- or 6-membered heterocyclyl wherein the 6-membered heterocyclyl is optionally substituted by two hydroxy substituents; R3 and R4 are each independently hydrogen or methyl; and n is an integer having a value of 5 or 6, are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment or prevention of various disorders, for example the treatment or prevention of allergic diseases and other inflammatory conditions, for example allergic rhinitis and asthma, infectious diseases and cancer, and may also be useful as vaccine adjuvants.
    Type: Application
    Filed: February 18, 2015
    Publication date: March 2, 2017
    Inventors: Keith BIGGADIKE, Aurelie Cecile CHAMPIGNY, Diane Mary COE, Daniel Terence TAPE, Stephen Allan SMITH
  • Systems and methods for integration of a positron emission tomography (PET) detector with a computed-tomography (CT) gantry
    Patent number: 9560970
    Abstract: Systems and methods for integration of a PET detector with a CT gantry are provided. One system includes an x-ray computed tomography (CT) gantry having a rotating portion and a stationary portion within a housing, and including a bore volume therethrough. The system also includes an x-ray source and an x-ray detector coupled to the rotating portion. The system further includes a positron emission tomography (PET) detector, wherein the PET detector is coupled to the stationary portion of the CT gantry, such that the PET detector extends at least partially into the CT gantry with at least a portion of the PET detector within the housing of the CT gantry.
    Type: Grant
    Filed: July 9, 2013
    Date of Patent: February 7, 2017
    Assignee: General Electric Company
    Inventors: Timothy Patrick Rose, Michael D. Maki, Chad Allan Smith
  • Pyrazolopyrimidine compounds
    Patent number: 9555036
    Abstract: Compounds of formula (I) and salts thereof: wherein R1 is n-C1-6alkyl or C1-2alkoxyC1-2alkyl-, R2 is halo, OH or C1-3alkyl, m is an integer having a value of 4, 5, 6 or 7, n is an integer having a value of 0, 1, 2 or 3, and p is an integer having a value of 0, 1 or 2, are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions, for example allergic rhinitis and asthma, infectious diseases and cancer, and may also be useful as vaccine adjuvants.
    Type: Grant
    Filed: August 22, 2013
    Date of Patent: January 31, 2017
    Assignee: GlaxoSmithKline LLC
    Inventors: Diane Mary Coe, Stephen Allan Smith
  • Pyrrolopyrimidines as therapeutic agents for the treatment of diseases
    Patent number: 9550785
    Abstract: The present invention relates to Compounds of formula (I) and salts thereof: wherein R1 is n-C3-6alkyl; R2 is hydrogen or methyl; R3 is hydrogen or C1-6alkyl, and m is an integer having a value of 0 to 3; are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions, for example allergic rhinitis and asthma, infectious diseases and cancer, and may also be useful as vaccine adjuvants.
    Type: Grant
    Filed: November 18, 2013
    Date of Patent: January 24, 2017
    Assignee: GlaxoSmithKline LLC
    Inventors: Diane Mary Coe, Stephen Allan Smith
  • Pyrrolopyrimidines as therapeutic agents for the treatment of diseases
    Patent number: 9540383
    Abstract: Compounds of formula (I) and salts thereof: wherein R1 is n-C4-6alkyl or C1-2alkoxyC1-2alkyl-; R2 is hydrogen or methyl; each R3 is hydroxy, halo or n-C1-3alkyl; m is an integer having a value of 2 to 4; n is an integer having a value of 0 to 3; and p is an integer having a value of 0 to 2, are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions, for example allergic rhinitis and asthma, infectious diseases and cancer, and may also be useful as vaccine adjuvants.
    Type: Grant
    Filed: November 18, 2013
    Date of Patent: January 10, 2017
    Assignee: GlaxoSmithKline LLC
    Inventors: Diane Mary Coe, Stephen Allan Smith
  • TILTING HEAD SUPPORT FOR MEDICAL IMAGING
    Publication number: 20160374630
    Abstract: A tilting head support for use in medical imaging is described. The tilting head support allows a patient to receive the equivalent of a tilted gantry exam study even when using a scanner gantry that does not tilt. In certain embodiments, the tilted head support assembly has metallic or sharp edge components, if present, positioned outside the imaging area when in use. In addition, in certain embodiments, the tilted head support assembly allows for user selection of a tilt angle from among a continuous range of available angles.
    Type: Application
    Filed: June 29, 2015
    Publication date: December 29, 2016
    Inventors: Chad Allan Smith, John Moore Boudry, Brandon Allan Smith, Jaime Lehrer
  • Tandem spring system
    Patent number: 9474365
    Abstract: A dual-rate tandem spring system is described. The system may include a higher force spring and a lower force spring. The spring system may comprise gas springs. The spring system may be included in a table system to provide lift or descent assist of objects such as a patient. A damper may be installed in the spring system to provide smooth transition between lower and higher force springs.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: October 25, 2016
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Brandon Allan Smith, Chad Allan Smith, Mark Tercha, Jaime Lehrer
  • TANDEM SPRING SYSTEM
    Publication number: 20160270523
    Abstract: A dual-rate tandem spring system is described. The system may include a higher force spring and a lower force spring. The spring system may comprise gas springs. The spring system may be included in a table system to provide lift or descent assist of objects such as a patient. A damper may be installed in the spring system to provide smooth transition between lower and higher force springs.
    Type: Application
    Filed: March 20, 2015
    Publication date: September 22, 2016
    Inventors: Brandon Allan Smith, Chad Allan Smith, Mark Tercha, Jaime Lehrer
  • Compounds
    Patent number: 9428512
    Abstract: The present invention relates to compounds of formula (I) and salts thereof: wherein R1 is n-C3-6alkyl; R2 is hydrogen or methyl; R3 is hydrogen or C1-6alkyl, and m is an integer having a value of 1 to 4; are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions, for example allergic rhinitis and asthma, infectious diseases and cancer, and may also be useful as vaccine adjuvants.
    Type: Grant
    Filed: November 18, 2013
    Date of Patent: August 30, 2016
    Assignee: GLAXOSMITHKLINE LLC
    Inventors: Diane Mary Coe, Stephen Allan Smith
  • 6-AMINO-PURIN-8-ONE COMPOUNDS
    Publication number: 20160228445
    Abstract: Compounds of formula (I): wherein R1 is C1-6alkylamino, C1-6alkoxy, or C3-7cycloalkyloxy; m is an integer having a value of 3 to 6; n is an integer having a value of 0 to 4; and salts thereof are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions for example allergic rhinitis and asthma, the treatment of infectious diseases and cancer, and may also be useful as vaccine adjuvants.
    Type: Application
    Filed: April 21, 2016
    Publication date: August 11, 2016
    Inventors: Keith BIGGADIKE, Diane Mary COE, Xiao Qing LEWELL, Charlotte Jane MITCHELL, Stephen Allan SMITH, Naimisha TRIVEDI
  • METHOD AND APPARATUS FOR TABLE-GANTRY ALIGNMENT IN AN IMAGING SYSTEM
    Publication number: 20160174929
    Abstract: Method and apparatus are provided for aligning a cradle supported by a table in an imaging system with a gantry scan plane in a bore of the gantry. More particularly, various embodiments provide a laser alignment structure having at least two alignment apertures arranged along an axis of the bore, and an adjustment device configured to adjust a position of the laser so that the laser beam is aligned with the alignment apertures. Highly accurate alignment of the cradle to the gantry scan plane is achieved by utilizing this apparatus in tandem with an imaging-based alignment analysis method.
    Type: Application
    Filed: December 17, 2014
    Publication date: June 23, 2016
    Inventors: Brandon Allan Smith, Ariel Friedlander
  • N-(4-HYDROXY-4-METHYL-CYCLOHEXYL)-4-PHENYL-BENZENESULFONAMIDES AND N-(4- HYDROXY-4-METHYL-CYCLOHEXYL)-4-(2-PYRIDYL)BENZENESULFONAMIDES AND THEIR THERAPEUTIC USE
    Publication number: 20160145206
    Abstract: The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain substituted N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and N-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamide compounds (collectively referred to herein as HMC compounds) that are useful, for example, in the treatment of disorders (e.g.
    Type: Application
    Filed: June 24, 2014
    Publication date: May 26, 2016
    Applicant: Pimco 2664 Limited
    Inventors: Lisa Patel, Stephen Allan Smith, Iain Robert Greig, Samuel Cameron Williams
  • 6-amino-purin-8-one compounds
    Patent number: 9346806
    Abstract: Compounds of formula (I): wherein R1 is C1-6alkylamino, C1-6alkoxy, or C3-7cycloalkyloxy; m is an integer having a value of 3 to 6; n is an integer having a value of 0 to 4; and salts thereof are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions for example allergic rhinitis and asthma, the treatment of infectious diseases and cancer, and may also be useful as vaccine adjuvants.
    Type: Grant
    Filed: October 13, 2011
    Date of Patent: May 24, 2016
    Assignee: GlaxoSmithKline LLC
    Inventors: Keith Biggadike, Diane Mary Coe, Xiao Qing Lewell, Charlotte Jane Mitchell, Stephen Allan Smith, Naimisha Trivedi
  • Compounds
    Patent number: 9266841
    Abstract: Pyrimidone compounds of formula (I): are inhibitors of the enzyme Lp-PLA2 and are of use in treating atherosclerosis.
    Type: Grant
    Filed: October 24, 2014
    Date of Patent: February 23, 2016
    Assignee: Glaxo Group Limited
    Inventors: Deirdre Mary Bernadette Hickey, Robert John Ife, Colin Andrew Leach, Ivan Leo Pinto, Stephen Allan Smith, Steven James Stanway
  • PYRAZOLOPYRIMIDINE COMPOUNDS
    Publication number: 20160022686
    Abstract: Compounds of formula (I) and salts thereof: wherein R1 is n-C1-6alkyl or C1-2alkoxyC1-2alkyl-, R2 is halo, OH or C1-3alkyl, m is an integer having a value of 4, 5, 6 or 7, n is an integer having a value of 0, 1, 2 or 3, and p is an integer having a value of 0, 1 or 2, are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions, for example allergic rhinitis and asthma, infectious diseases and cancer, and may also be useful as vaccine adjuvants.
    Type: Application
    Filed: October 1, 2015
    Publication date: January 28, 2016
    Inventors: Diane Mary Coe, Stephen Allan Smith