Patents by Inventor Allen Hopper

Allen Hopper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions including 6-aminohexanoic acid derivatives as HDAC inhibitors
    Patent number: 9796664
    Abstract: This invention relates to compounds of Formula (I) wherein Cy1, L1, Y, R1, L2, and Ar2 are defined herein, for the treatment of cancers, inflammatory disorders, and neurological conditions.
    Type: Grant
    Filed: January 12, 2016
    Date of Patent: October 24, 2017
    Assignee: BIOMARIN PHARMACEUTICAL INC.
    Inventors: James R. Rusche, Norton P. Peet, Allen Hopper
  • COMPOSITIONS INCLUDING 6-AMINOHEXANOIC ACID DERIVATIVES AS HDAC INHIBITORS
    Publication number: 20160122290
    Abstract: This invention relates to compounds of Formula (I) wherein Cy1, L1, Y, R1, L2, and Ar2 are defined herein, for the treatment of cancers, inflammatory disorders, and neurological conditions.
    Type: Application
    Filed: January 12, 2016
    Publication date: May 5, 2016
    Inventors: James R. Rusche, Norton P. Peet, Allen Hopper
  • 2-SUBSTITUTED-ETHYNYLTHIAZOLE DERIVATIVES AND USES OF SAME
    Publication number: 20130231321
    Abstract: The present invention provides 2-substituted-ethynylthiazole derivatives of formula (I): wherein R1, R2 and X are as defined herein, or a pharmaceutically acceptable salt thereof; and pharmaceutical compositions and methods of using same.
    Type: Application
    Filed: April 16, 2013
    Publication date: September 5, 2013
    Applicant: H. LUNDBECK A/S
    Inventors: Mathivanan Packiarajan, Allen Hopper, Anette Graven Sams, Gitte Kobberoee Mikkelsen, Michel Grenon
  • 2-substituted-ethynylthiazole derivatives and uses of same
    Patent number: 8440837
    Abstract: The present invention provides 2-substituted-ethynylthiazole derivatives of formula (I): wherein R1, R2 and X are as defined herein, or a pharmaceutically acceptable salt thereof; and pharmaceutical compositions and methods of using same.
    Type: Grant
    Filed: October 20, 2010
    Date of Patent: May 14, 2013
    Assignee: H. Lundbeck A/S
    Inventors: Allen Hopper, Anette Graven Sams, Gitte Kobberoee Mikkelsen, Mathivanan Packiarajan, Michel Grenon
  • 2-SUBSTITUTED-ETHYNYLTHIAZOLE DERIVATIVES AND USES OF SAME
    Publication number: 20110092475
    Abstract: The present invention provides 2-substituted-ethynylthiazole derivatives of formula (I): wherein R1, R2 and X are as defined herein, or a pharmaceutically acceptable salt thereof; and pharmaceutical compositions and methods of using same.
    Type: Application
    Filed: October 20, 2010
    Publication date: April 21, 2011
    Applicant: H. LUNDBECK A/S
    Inventors: Allen Hopper, Anette Graven Sams, Gitte Kobberoee Mikkelsen, Mathivanan Packiarajan, Michel Grenon
  • Phosphodiesterase 4 inhibitors
    Publication number: 20110046146
    Abstract: PDE4 inhibition is achieved by novel compounds, e.g., N-substituted aniline and diphenylamine analogs. The compounds of the present invention are of Formula I: wherein R1, R2, R3and R4 are as defined herein.
    Type: Application
    Filed: November 21, 2006
    Publication date: February 24, 2011
    Inventors: Richard Schumacher, William Brubaker, Michael De Vivo, Hans-Jurgen Hess, Allen Hopper, Ashok Tehim, Ruiping Liu, Axel Unterbeck
  • Phosphodiesterase 4 inhibitors
    Patent number: 7723348
    Abstract: Selective PDE4 inhibition is achieved by aryl and heteroaryl pyrazole compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds such as rolipram and show selectivity with regard to inhibition of other classes of PDEs.
    Type: Grant
    Filed: April 24, 2008
    Date of Patent: May 25, 2010
    Assignee: Memory Pharmaceuticals Corporation
    Inventors: Allen Hopper, Robert F. Dunn, Erik Mikal Kuester, Richard D. Conticello
  • Phosphodiesterase 4 inhibitors
    Patent number: 7696198
    Abstract: Selective PDE4 inhibition is achieved by 4-(substituted-phenyl)-2-pyrrolidinone compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds like rolipram and show selectivity with regard to inhibition of other classes of PDEs. The compounds of the present invention are of formula I: wherein R1, R2, and R3 are as defined herein.
    Type: Grant
    Filed: April 16, 2004
    Date of Patent: April 13, 2010
    Assignee: Memory Pharmaceuticals Corporation
    Inventors: Ashok Tehim, Allen Hopper, Ruiping Liu, Erik Kuester, Robert F. Dunn, Thomas E. Renau
  • CERTAIN THIENOPYRIMIDINE DERIVATIVES AS PHOSPHODIESTERASE 10 INHIBITORS
    Publication number: 20100010017
    Abstract: Certain thienopyrimidine derivatives are useful for the inhibition of PDE10 enzymes, and thus are useful for treating psychiatric or neurological syndromes, e.g., psychoses, obsessive-compulsive disorder and/or Parkinson's disease, as well as, for example, treating a disease state modulated by PDE10 activity.
    Type: Application
    Filed: June 29, 2009
    Publication date: January 14, 2010
    Applicant: Memory Pharmaceuticals Corporation
    Inventors: Ruiping Liu, Mark Phillip Arrington, Allen Hopper, Ashok Tehim
  • PHOSPHODIESTERASE 4 INHIBITORS
    Publication number: 20100010020
    Abstract: PDE4 inhibition is achieved by novel compounds of the Formula I: wherein R1 and R2 are as defined herein.
    Type: Application
    Filed: September 22, 2009
    Publication date: January 14, 2010
    Inventors: Ruiping LIU, Hans-Jurgen Ernst Hess, Allen Hopper, Ashok Tehim, Yujing Rong
  • PHOSPHODIESTERASE 4 INHIBITORS
    Publication number: 20090306156
    Abstract: Selective PDE4 inhibition is achieved by novel compounds, e.g., 4-(substituted-phenyl)-2-pyrrolidinone compounds. The compounds of the present invention are of formula I: wherein R1, R2, and R3 are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.
    Type: Application
    Filed: August 4, 2009
    Publication date: December 10, 2009
    Inventors: Allen HOPPER, Robert Francis Dunn, Erik Mikal Kuester, Richard Dennis Conticello, Ruiping Liu, Ashok Tehim
  • Phosphodiesterase 4 inhibitors
    Patent number: 7585882
    Abstract: Selective PDE4 inhibition is achieved by novel compounds, e.g., 4-(substituted-phenyl)-2-pyrrolidinone compounds. The compounds of the present invention are of formula I: wherein R1, R2, and R3 are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.
    Type: Grant
    Filed: October 20, 2005
    Date of Patent: September 8, 2009
    Assignee: Memory Pharmaceuticals Corporation
    Inventors: Allen Hopper, Robert Francis Dunn, Erik Mikal Kuester, Richard Dennis Conticello, Ruiping Liu, Ashok Tehim
  • PHOSPHODIESTERASE 4 INHIBITORS
    Publication number: 20090221661
    Abstract: Selective PDE4 inhibition is achieved by aryl and heteroaryl pyrazole compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds such as rolipram and show selectivity with regard to inhibition of other classes of PDEs.
    Type: Application
    Filed: February 20, 2009
    Publication date: September 3, 2009
    Inventors: Allen Hopper, Erik Kuester, Robert Dunn, Richard Conticello
  • Certain thienopyrimidine derivatives as phosphodiesterase 10 inhibitors
    Patent number: 7576080
    Abstract: Certain thienopyrimidine derivatives are useful for the inhibition of PDE10 enzymes, and thus are useful for treating psychiatric or neurological syndromes, e.g., pyschoses, obsessive-compulsive disorder and/or Parkinson's disease, as well as, for example, treating a disease state modulated by PDE10 activity.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: August 18, 2009
    Assignee: Memory Pharmaceuticals Corporation
    Inventors: Ruiping Liu, Mark Phillip Arrington, Allen Hopper, Ashok Tehim
  • PHOSPHODIESTERASE 4 INHIBITORS
    Publication number: 20090176799
    Abstract: Selective PDE4 inhibition is achieved by 4-(substituted-phenyl)-2-pyrrolidinone compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds like rolipram and show selectivity with regard to inhibition of other classes of PDEs. The compounds of the present invention are of formula I: wherein R1, R2, and R3 are as defined herein.
    Type: Application
    Filed: December 1, 2008
    Publication date: July 9, 2009
    Inventors: Liu Ruiping, Mike De Vivo, Hans-Jurgen Ernst Hess, Allen Hopper, Erik Kreuster, Ashok Tehim
  • PHOSPHODIESTERASE 4 INHIBITORS
    Publication number: 20090118270
    Abstract: PDE4 inhibition is achieved by novel compounds, e.g., N-substituted diarylamine analogs. The compounds of the present invention are of Formulas I-III: wherein A, B, D, E, G, J, K, R1, R2, R3, R4, R11, R12, R13, R14, R21, R22, R23 and R24 are as defined herein.
    Type: Application
    Filed: December 5, 2008
    Publication date: May 7, 2009
    Inventors: Francisco Xavier Talamas, Joan Marie Caroon, Robert Dunn, Allen Hopper, Erik Kuester, Richard Schumacher, Ashok Tehim
  • Phosphodiesterase 4 inhibitors
    Patent number: 7495017
    Abstract: Selective PDE4 inhibition is achieved by aryl and heteroaryl pyrazole compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds such as rolipram and show selectivity with regard to inhibition of other classes of PDEs.
    Type: Grant
    Filed: May 1, 2007
    Date of Patent: February 24, 2009
    Assignee: Memory Pharmaceuticals Corporation
    Inventors: Allen Hopper, Erik Kuester, Robert Dunn, Richard Conticello
  • Phosphodiesterase 4 inhibitors
    Patent number: 7432266
    Abstract: Selective PDE4 inhibition is achieved by aryl and heteroaryl pyrazole compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds such as rolipram and show selectivity with regard to inhibition of other classes of PDEs.
    Type: Grant
    Filed: October 14, 2005
    Date of Patent: October 7, 2008
    Assignee: Memory Pharmaceuticals Corporation
    Inventors: Allen Hopper, Robert F. Dunn, Erik Mikal Kuester, Richard D. Conticello
  • PHOSPHODIESTERASE 4 INHIBITORS
    Publication number: 20080207660
    Abstract: Selective PDE4 inhibition is achieved by aryl and heteroaryl pyrazole compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds such as rolipram and show selectivity with regard to inhibition of other classes of PDEs.
    Type: Application
    Filed: April 24, 2008
    Publication date: August 28, 2008
    Inventors: Allen HOPPER, Robert F. Dunn, Erik Mikal Kuester, Richard D. Conticello
  • PHOSPHODIESTERASE 4 INHIBITORS
    Publication number: 20080119495
    Abstract: PDE4 inhibition is achieved by novel compounds of the Formula I: wherein R1 and R2 are as defined herein.
    Type: Application
    Filed: December 14, 2007
    Publication date: May 22, 2008
    Inventors: Ruiping LIU, Hans-Jurgen Ernst Hess, Allen Hopper, Ashok Tehim, Yajing Rong