Patents by Inventor Allen Hopper

Allen Hopper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080119495
    Abstract: PDE4 inhibition is achieved by novel compounds of the Formula I: wherein R1 and R2 are as defined herein.
    Type: Application
    Filed: December 14, 2007
    Publication date: May 22, 2008
    Inventors: Ruiping LIU, Hans-Jurgen Ernst Hess, Allen Hopper, Ashok Tehim, Yajing Rong
  • Patent number: 7342021
    Abstract: PDE4 inhibition is achieved by novel compounds of the Formula I: wherein R1 and R2 are as defined herein.
    Type: Grant
    Filed: February 8, 2002
    Date of Patent: March 11, 2008
    Assignee: Memory Pharmaceuticals Corp.
    Inventors: Ruiping Liu, Hans-Jurgen Ernst Hess, Allen Hopper, Ashok Tehim, Yajing Rong
  • Publication number: 20070299067
    Abstract: The present invention is directed to certain quinoline and isoquinoline compounds that are PDE10 inhibitors, pharmaceutical compositions containing such compounds and processes for preparing such compounds. The invention is also directed to methods of treating diseases mediated by PDE10 enzyme, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.
    Type: Application
    Filed: March 8, 2007
    Publication date: December 27, 2007
    Inventors: Ruiping Liu, Mark Arrington, Allen Hopper, Richard Conticello, Stephen Hitchcock
  • Publication number: 20070287707
    Abstract: The present invention if directed to certain cinnoline compounds that are PDE10 inhibitors, pharmaceutical compounds containing the same and processes for preparing the same. The invention is also directed to methods of treating diseases mediated by PDE10 enzyme such as obesity, non-insulin dependent diabetes, schizophrenia or bipolar disorder, obsessive-compulsive disorder, and the like.
    Type: Application
    Filed: February 27, 2007
    Publication date: December 13, 2007
    Inventors: Mark Arrington, Allen Hopper, Richard Conticello, Hans-Jurgen Hess, Stephen Hitchcock
  • Publication number: 20070265270
    Abstract: The present invention is directed to certain cinnoline compounds that are PDE10 inhibitors, pharmaceutical compositions containing such compounds and process for preparing such compounds. The invention is also directed to methods of treating diseases treatable by modulation of PDE10 enzyme, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.
    Type: Application
    Filed: February 20, 2007
    Publication date: November 15, 2007
    Inventors: Stephen Hitchcock, Ruiping Liu, Mark Arrington, Allen Hopper, Richard Conticello, Truc Nguyen, M. Danca, Carla Gauss
  • Publication number: 20070265256
    Abstract: The present invention is directed to certain cinnoline compounds that are PDE10 inhibitors, pharmaceutical compositions containing such compounds and process for preparing such compounds. This invention is also directed to methods of treating diseases treatable by inhibition of PDE10 enzyme, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.
    Type: Application
    Filed: February 20, 2007
    Publication date: November 15, 2007
    Inventors: Mark Arrington, Ruiping Liu, Allen Hopper, Richard Conticello, Truc Nguyen, Carla Gauss, Roland Burli, Stephen Hitchcock, Essa Hu, Roxanne Kunz, Thomas Nixey, Shannon Rumfelt, Nign Chen
  • Publication number: 20070265258
    Abstract: The present invention if directed to certain quinazoline compounds that are PDE10 inhibitors, pharmaceutical compounds containing the same and processes for preparing the same. The invention is also directed to methods of treating diseases treatable by PDE10 enzyme such as obesity, non-insulin dependent diabetes, schizophrenia or bipolar disorder, obsessive-compulsive disorder, and the like.
    Type: Application
    Filed: March 5, 2007
    Publication date: November 15, 2007
    Inventors: Ruiping Liu, Mark Arrington, Allen Hopper, Richard Conticello, Truc Nguyen, Carla Gauss, Stephen Hitchcock
  • Publication number: 20070259896
    Abstract: Certain thienopyrimidine derivatives are useful for the inhibition of PDE10 enzymes, and thus are useful for treating psychiatric or neurological syndromes, e.g., pyschoses, obsessive-compulsive disorder and/or Parkinson's disease, as well as, for example, treating a disease state modulated by PDE10 activity.
    Type: Application
    Filed: December 22, 2005
    Publication date: November 8, 2007
    Inventors: Ruiping Liu, Mark Arrington, Allen Hopper, Ashok Tehim
  • Publication number: 20070254913
    Abstract: Selective PDE4 inhibition is achieved by aryl and heteroaryl pyrazole compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds such as rolipram and show selectivity with regard to inhibition of other classes of PDEs.
    Type: Application
    Filed: April 19, 2007
    Publication date: November 1, 2007
    Inventors: Robert Dunn, Eric Kuester, Richard Conticello, Allen Hopper
  • Publication number: 20070203197
    Abstract: Selective PDE4 inhibition is achieved by aryl and heteroaryl pyrazole compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds such as rolipram and show selectivity with regard to inhibition of other classes of PDEs.
    Type: Application
    Filed: May 1, 2007
    Publication date: August 30, 2007
    Inventors: Allen Hopper, Erik Kuester, Robert Dunn, Richard Conticello
  • Patent number: 7235579
    Abstract: Selective PDE4 inhibition is achieved by 4-(substituted-phenyl)-2-pyrrolidinone compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds like rolipram and show selectivity with regard to inhibition of other classes of PDEs. The compounds of the present invention are of formula I: wherein R1, R2, and R3 are as defined herein.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: June 26, 2007
    Assignee: Memory Pharmaceuticals Corp.
    Inventors: Ruiping Liu, Mike De Vivo, Hans-Jurgen Ernst Hess, Allen Hopper, Erik Kuester, Ashok Tehim
  • Patent number: 7226930
    Abstract: Selective PDE4 inhibition is achieved by aryl and heteroaryl pyrazole compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds such as rolipram and show selectivity with regard to inhibition of other classes of PDEs.
    Type: Grant
    Filed: April 16, 2004
    Date of Patent: June 5, 2007
    Assignee: Memory Pharmaceutical Corporation
    Inventors: Allen Hopper, Erik Kuester, Robert Dunn, Richard Conticello
  • Publication number: 20070123570
    Abstract: PDE4 inhibition is achieved by novel compounds, e.g., aminoindazole and aminobenzofuran analogs, The compounds of the present invention are of Formulas I and II: wherein R1, R2, R3, R4, R7 and R8 are as defined herein.
    Type: Application
    Filed: December 21, 2006
    Publication date: May 31, 2007
    Inventors: Richard Schumacher, Allen Hopper, Ashok Tehim
  • Publication number: 20070093515
    Abstract: Provided are certain quinazolines that are PDE10 inhibitors, pharmaceutical compositions, containing the same and processes for preparing the same. Also provided are methods of treating diseases treatable by PDE10 enzyme such as obesity, non-insulin dependent diabetes, schizophrenia or bipolar disorder, obsessive-compulsive disorder, and the like, by administering those certain quinazolines.
    Type: Application
    Filed: August 16, 2006
    Publication date: April 26, 2007
    Inventors: Mark Arrington, Richard Conticello, Carla Gauss, Stephen Hitchcock, Allen Hopper, Ruiping Liu, Truc Nguyen, Ashok Tehim
  • Publication number: 20070093510
    Abstract: PDE4 inhibition is achieved by novel compounds of the Formula I: wherein R1 and R2 are as defined herein.
    Type: Application
    Filed: August 8, 2003
    Publication date: April 26, 2007
    Applicant: MEMORY PHARMACEUTICALS CORP.
    Inventors: Ashok Tehim, Allen Hopper, Ruiping Liu, Hans-Jurgen Hess, Yajing Rong
  • Patent number: 7205320
    Abstract: PDE4 inhibition is achieved by novel compounds, e.g., N-substituted aniline and diphenylamine analogs. The compounds of the present invention are of Formula I: wherein R1, R2, R3 and R4 are as defined herein.
    Type: Grant
    Filed: January 12, 2004
    Date of Patent: April 17, 2007
    Assignee: Memory Pharmaceuticals Corp.
    Inventors: Richard A. Schumacher, William F. Brubaker, Michael De Vivo, Hans-Jürgen Ernst Hess, Allen Hopper, Ashok Tehim, Ruiping Liu, Axel Unterbeck
  • Publication number: 20070078139
    Abstract: PDE4 inhibition is achieved by novel compounds, e.g., N-substituted aniline and diphenylamine analogs. The compounds of the present invention are of Formula I: wherein R1, R2, R3and R4 are as defined herein.
    Type: Application
    Filed: November 21, 2006
    Publication date: April 5, 2007
    Inventors: Richard Schumacher, William Brubaker, Michael De Vivo, Hans-Jurgen Hess, Allen Hopper, Ashok Tehim, Ruiping Liu, Axel Unterbeck
  • Publication number: 20070049611
    Abstract: PDE4 inhibition is achieved by novel compounds, e.g., N-substituted diarylamine analogs. The compounds of the present invention are of Formulas I-III: wherein A, B, D, E, G, J, K, R1, R2, R3, R4, R11, R12, R13, R14, R21, R22, R23 and R24 are as defined herein.
    Type: Application
    Filed: June 9, 2006
    Publication date: March 1, 2007
    Inventors: Francisco Talamas, Joan Caroon, Robert Dunn, Allen Hopper, Eric Kuester, Richard Schumacher, Ashok Tehim
  • Publication number: 20060211865
    Abstract: PDE4 inhibition is achieved by novel nitroxide compounds, e.g., N-substituted aniline and diphenylamine analogs. The compounds of the present invention are of Formulas I-III: wherein A, B, D, R1, R2, R3, R7, R8, R9, R10 and R6 are as defined herein.
    Type: Application
    Filed: March 20, 2006
    Publication date: September 21, 2006
    Inventors: Richard Schumacher, Elizabeth Graham, Allen Hopper, Ashok Tehim
  • Publication number: 20060160814
    Abstract: The present disclosure relates generally to the field of phosphodiesterase 10 (PDE10) enzyme inhibition by cinnoline compounds of Formulas I and II: wherein R1—R3 and R15—R18 are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.
    Type: Application
    Filed: September 2, 2005
    Publication date: July 20, 2006
    Inventors: Mark Arrington, Ruiping Liu, Richard Conticello, Carla Gauss, Allen Hopper, Truc Nguyen, Ashok Tehim