Patents by Inventor Allen T. Hopper

Allen T. Hopper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions including 6-aminohexanoic acid derivatives as HDAC inhibitors
    Patent number: 9265734
    Abstract: This invention relates to compounds of Formula (I) wherein Cy1, L1, Y, R1, L2, and Ar2 are defined herein, for the treatment of cancers, inflammatory disorders, and neurological conditions.
    Type: Grant
    Filed: September 3, 2009
    Date of Patent: February 23, 2016
    Assignee: BIOMARIN PHARMACEUTICAL INC.
    Inventors: James R. Rusche, Norton P. Peet, Allen T. Hopper
  • Benzamides
    Publication number: 20150283134
    Abstract: The present invention is directed to benzamide containing compounds which inhibit the P2X7 receptor
    Type: Application
    Filed: June 19, 2015
    Publication date: October 8, 2015
    Inventors: John Paul Kilburn, Lars Kyhn Rasmussen, Mikkel Jessing, Eman Mohamed Eldemenky, Bin Chen, Yu Jiang, Allen T. Hopper
  • Benzamides
    Patent number: 9102591
    Abstract: The present invention is directed to benzamide containing compounds which inhibit the P2X7 Receptor.
    Type: Grant
    Filed: October 10, 2013
    Date of Patent: August 11, 2015
    Assignee: H. Lundbeck A/S
    Inventors: John Paul Kilburn, Lars Kyhn Rasmussen, Mikkel Jessing, Eman Mohammed Eldemenky, Bin Chen, Yu Jiang, Allen T. Hopper
  • Benzamides
    Publication number: 20140107340
    Abstract: The present invention is directed to benzamide containing compounds which inhibit the P2X7 receptor
    Type: Application
    Filed: October 10, 2013
    Publication date: April 17, 2014
    Applicant: H. Lundbeck A/S
    Inventors: John Paul Kilburn, Lars Kyhn Rasmussen, Mikkel Jessing, Eman Mohammed Eldemenky, Bin Chen, Yu Jiang, Allen T. Hopper
  • Compositions Including 6-Aminohexanoic Acid Derivatives As HDAC Inhibitors
    Publication number: 20120094971
    Abstract: This invention relates to compounds of Formula (I) wherein Cy1, L1, Y, R1, L2, and Ar2 are defined herein, for the treatment of cancers, inflammatory disorders, and neurological conditions.
    Type: Application
    Filed: September 3, 2009
    Publication date: April 19, 2012
    Applicant: REPLIGEN CORPORATION
    Inventors: James R. Rusche, Norton P. Peet, Allen T. Hopper
  • Heterocyclic compounds, methods for the preparation thereof, and uses thereof
    Patent number: 7994199
    Abstract: The compounds of the present invention are of formula I: wherein A, R3, R4 is as defined herein, are useful as ligands for nicotinic receptors.
    Type: Grant
    Filed: March 16, 2010
    Date of Patent: August 9, 2011
    Assignee: Memory Pharmaceuticals Corporation
    Inventors: Brian Herbert, Wenge Xie, Truc Minh Nguyen, Allen T Hopper, Ashok Tehim
  • HETEROCYCLIC COMPOUNDS, METHODS FOR THE PREPARATION THEREOF, AND USES THEREOF
    Publication number: 20100173891
    Abstract: The compounds of the present invention are of formula I: wherein A, R3, R4 is as defined herein, are useful as ligands for nicotinic receptors.
    Type: Application
    Filed: March 16, 2010
    Publication date: July 8, 2010
    Inventors: Brian Herbert, Wenge Xie, Truc Minh Nguyen, Allen T. Hopper, Ashok Tehim
  • PHOSPHODIESTERASE 4 INHIBITORS
    Publication number: 20100173942
    Abstract: PDE4 inhibition is achieved by novel nitroxide compounds, e.g., N-substituted aniline and diphenylamine analogs. The compounds of the present invention are of Formulas I-III: wherein A, B, D, R1, R2, R3, R7, R8, R9, R10 and R6 are as defined herein.
    Type: Application
    Filed: March 16, 2010
    Publication date: July 8, 2010
    Inventors: Richard A. Schumacher, Elizabeth Doorly Graham, Allen T. Hopper, Ashok Tehim
  • Phosphodiesterase 4 inhibitors
    Patent number: 7700631
    Abstract: PDE4 inhibition is achieved by novel nitroxide compounds, e.g., N-substituted aniline and diphenylamine analogs. The compounds of the present invention are of Formulas I-III: wherein A, B, D, R1, R2, R3, R7, R8, R9, R10 and R6 are as defined herein.
    Type: Grant
    Filed: March 20, 2006
    Date of Patent: April 20, 2010
    Assignee: Memory Pharmaceuticals Corporation
    Inventors: Richard A. Schumacher, Elizabeth Doorly Graham, Allen T. Hopper, Ashok Tehim
  • Heterocyclic compounds, methods for the preparation thereof, and uses thereof
    Patent number: 7700630
    Abstract: The compounds of the present invention are of formula I: wherein A, R3, R4 is as defined herein, are useful as ligands for nicotinic receptors.
    Type: Grant
    Filed: April 6, 2007
    Date of Patent: April 20, 2010
    Assignee: Memory Pharmaceuticals Corporation
    Inventors: Brian Herbert, Wenge Xie, Truc Minh Nguyen, Allen T Hopper, Ashok Tehim
  • PHOSPHODIESTERASE 4 INHIBITORS, INCLUDING AMINOINDAZOLE AND AMINOBENZOFURAN ANALOGS
    Publication number: 20100093806
    Abstract: PDE4 inhibition is achieved by novel compounds, e.g., aminoindazole and aminobenzofuran analogs. The compounds of the present invention are of Formulas I and II: wherein R1, R2, R3, R4, R7 and R8 are as defined herein.
    Type: Application
    Filed: December 17, 2009
    Publication date: April 15, 2010
    Inventors: Richard A. SCHUMACHER, Allen T. Hopper, Ashok Tehim
  • PHOSPHODIESTERASE 4 INHIBITORS
    Publication number: 20100029689
    Abstract: PDE4 inhibition is achieved by novel compounds, e.g., N-substituted aniline and diphenylamine analogs. The compounds of the present invention are of Formula I: wherein R1, R2, R3, and R4 are as defined herein.
    Type: Application
    Filed: July 2, 2009
    Publication date: February 4, 2010
    Applicants: MEMORY PHARMACEUTICALS CORPORATION, ROCHE PALO ALTO LLC
    Inventors: Allen T. HOPPER, Joan Marie CAROON, Elbert CHIN, Robert F. DUNN, Sharada Shenvi LABADIE, Jim LI, Richard Allen SCHUMACHER, Francisco Xavier TALAMAS
  • Phosphodiesterase 4 inhibitors, including aminoindazole and aminobenzofuran analogs
    Patent number: 7655802
    Abstract: PDE4 inhibition is achieved by novel compounds, e.g., aminoindazole and aminobenzofuran analogs. The compounds of the present invention are of Formulas I and II: wherein R1, R2, R3, R4, R7 and R8 are as defined herein.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: February 2, 2010
    Assignee: Memory Pharmaceuticals Corporation
    Inventors: Richard A. Schumacher, Allen T. Hopper, Ashok Tehim
  • PHOSPHODIESTERASE 4 INHIBITORS
    Publication number: 20100004236
    Abstract: PDE4 inhibition is achieved by novel compounds of the Formula I: wherein R1 and R2 are as defined herein.
    Type: Application
    Filed: February 26, 2009
    Publication date: January 7, 2010
    Inventors: Ashok Tehim, Allen T. Hopper, Ruiping Liu, Hans-Juregen Ernst Hess, Yajing Rong
  • PHOSPHODIESTERASE 4 INHIBITORS
    Publication number: 20090325982
    Abstract: PDE4 inhibition is achieved by novel compounds of the Formula I: wherein R1 and R2 are as defined herein.
    Type: Application
    Filed: September 4, 2009
    Publication date: December 31, 2009
    Inventors: Allen T. HOPPER, Ruiping LIU
  • Heterocyclic compounds, methods for the preparation thereof, and uses thereof
    Publication number: 20090105215
    Abstract: The compounds of the present invention are of formula I: wherein A, R3, R4 is as defined herein, are useful as ligands for nicotinic receptors.
    Type: Application
    Filed: April 6, 2007
    Publication date: April 23, 2009
    Inventors: Brian Herbert, Wenge Xie, Truc Minh Nguyen, Allen T. Hopper, Ashok Tehim
  • Phosphodiesterase 10 inhibitors
    Publication number: 20090099175
    Abstract: The present invention if directed to certain cinnoline compounds that are PDE10 inhibitors, pharmaceutical compositions containing such compounds and processes for preparing such compounds. The invention is also directed to methods of treating diseases mediated by PDE10 enzyme, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.
    Type: Application
    Filed: February 28, 2007
    Publication date: April 16, 2009
    Inventors: Mark P. Arrington, Allen T. Hopper, Richard D. Conticello, Truc M. Nguyen, Hans-Jurgen E. Hess, Carla Maria Gauss, Stephen A. Hitchcock
  • PHOSPHODIESTERASE 4 INHIBITORS, INCLUDING N-SUBSTITUTED ANILINE AND DIPHENYLAMINE ANALOGS
    Publication number: 20090048255
    Abstract: PDE4 inhibition is achieved by novel compounds, e.g., N-substituted aniline and diphenylamine analogs. The compounds of the present invention are of Formula I: wherein R1, R2, R3 and R4 are as defined herein.
    Type: Application
    Filed: July 17, 2008
    Publication date: February 19, 2009
    Inventors: Richard A. SCHUMACHER, Allen T. HOPPER, Ashok TEHIM, Hans-Jurgen Ernst HESS, Axel UNTERBECK, Erik KUESTER, William Frederick BRUBAKER, JR., Robert F. DUNN
  • PHOSPHODIESTERASE 4 INHIBITORS
    Publication number: 20080269260
    Abstract: PDE4 inhibition is achieved by novel compounds of the Formula I: wherein R1 and R2 are as defined herein.
    Type: Application
    Filed: February 14, 2008
    Publication date: October 30, 2008
    Inventors: Allen T. Hopper, Ruiping Liu
  • Phosphodiesterase 4 inhibitors, including N-substituted aniline and diphenylamine analogs
    Patent number: 7405230
    Abstract: PDE4 inhibition is achieved by novel compounds, e.g., N-substituted aniline and diphenylamine analogs. The compounds of the present invention are of Formula I: wherein R1, R2, R3 and R4 are as defined herein.
    Type: Grant
    Filed: July 21, 2003
    Date of Patent: July 29, 2008
    Assignee: Memory Pharmaceuticals Corporation
    Inventors: Richard A. Schumacher, Allen T. Hopper, Ashok Tehim, Hans-Jurgen Ernst Hess, Axel Unterbeck, Erik Kuester, William Frederick Brubaker, Jr., Robert F. Dunn