Abstract: Valve components positioned in fluid connector assemblies, including universal fluid connector assemblies, are shown. A valve component is designed to open or close based on fluid pressure from a medical fluid applied to the valve component. Normally, when no force is acting on the valve component, the valve component is in an open position and portions of the valve components are spaced apart by a threshold force, thus forming a valve chamber. However, in an exemplary embodiment, when an applied force by the medical fluid is at least at the threshold force, the portions of the valve component contact each other and the valve component transitions to a closed position, thereby preventing the medical fluid from passing through the valve component, and accordingly, preventing the medical fluid from passing through the fluid connector assembly.

Abstract: A fluid connector device for a blood collection system is disclosed. In order to be safely used with different gauges, the fluid connector device can regulate blood flow therethrough based upon the catheter gauge. For example, when 18-to-22-gauge catheters are used, the fluid connector device regulates the blood flow by positioning a slider assembly (within the fluid connector device) to a setting that allows a single channel to transmit blood through the fluid connector device into a fluid inlet and out of a fluid outlet of the fluid connector device. Alternatively, in another example, when 24-gauge (or greater) catheters are used, the slider assembly can be actuated to a new position, which allows multiple channels to transmit blood into the fluid inlet and out of the fluid outlet. By regulating blood flow, the fluid connector device can limit or prevent hemolysis, while being universally used with different catheters.

Abstract: A flow restriction device may include a male luer connector portion, a female luer connector portion, and a flexible tube. The male luer connector portion defies a first lumen. The female luer connector portion defines a second lumen. The flexible tube defines a third lumen. The third lumen is in fluid communication with the first lumen and the second lumen. The third lumen has a diameter of about 0.02 inches.

Abstract: Needleless connectors are described herein. A needleless connector includes a housing and a flexible valve element. The housing includes a cavity, a proximal fluid port in fluid communication with the cavity, and a distal fluid port in fluid communication with the cavity. The flexible valve element is disposed within the cavity. The flexible valve element can selectively permit flow between the proximal fluid port and the distal fluid port.

Abstract: Fluid connector systems that can include first and second connectors that are couplable together to form a fluid pathway through the fluid connector system when the first and second connectors are coupled together, and can resist fluid flow through each of the first and second connectors when the first and second connectors are separated from each other, where the first and second connectors can include a valve within a channel and configured resist fluid flow through the respective first or second connector in an closed position and to reduce the resistance to fluid flow through the first or second connector in an open position, and the first and second connectors including one or more arm configured to engage each other to form a snap fitting feature that can resist separation therebetween.

Abstract: A flow control device includes an upper housing, a lower housing, a chamber interposed between and defined by the upper and lower housings, and a valve member. The upper housing includes a primary inlet having an internal surface defining a cavity and a secondary inlet. The lower housing defines an outlet of the flow control device. The chamber fluidly connects the primary and secondary inlets with the outlet. A valve member is reciprocally disposed at least partially in the cavity and partially in the chamber to (i) selectively permit fluid flow in the primary inlet in a first direction when a fluid level in the chamber is below a predetermined level, and (ii) prevent fluid backflow in a second direction opposite to the first direction when the fluid level in the chamber is above the predetermined level.

Abstract: A flow restriction device including a housing forming a fluid flow path with a resilient valve positioned between first and second segments of the fluid path, where a segment of the fluid path includes a spiral or involute shape, and where the resilient valve is responsive to a change in pressure along the fluid path such that the resilient valve can move or bias toward the fluid path to restrict a fluid flow through the fluid path, thereby reducing a flow rate and pressure of the fluid, and where the fluid is blood, reducing the hemolysis index of the blood, and in some instances the resilient valve stopping the fluid flow through the fluid flow path responsive to exceeding a pressure along the fluid path to reduce the hemolysis index of the blood.

Abstract: A flow control device includes an upper housing, a lower housing, a chamber interposed between and defined by the upper and lower housings, and a valve member. The upper housing includes a primary inlet having an internal surface defining a cavity and a secondary inlet. The lower housing defines an outlet of the flow control device. The chamber fluidly connects the primary and secondary inlets with the outlet. A valve member is reciprocally disposed at least partially in the cavity and partially in the chamber to (i) selectively permit fluid flow in the primary inlet in a first direction when a fluid level in the chamber is below a predetermined level, and (ii) prevent fluid backflow in a second direction opposite to the first direction when the fluid level in the chamber is above the predetermined level.

Abstract: Fluid connector systems that can include first and second valve assemblies that are couplable together to form a fluid pathway through the fluid connector system when the first and second valve assemblies are coupled together, and can resist fluid flow through each of the first and second valve assemblies when the first and second valve assemblies are separated from each other, where the first and second valve assemblies can include a compressible element or post positioned within a channel and configured resist fluid flow through the respective first or second valve assembly in a first position and to reduce the resistance to fluid flow through the first or second valve assembly in a second position, and the first and second valve assemblies including a sleeve and one or more arm configured to engage each other to form a snap fitting feature that can resist separation therebetween.

Abstract: A flow restriction device may include a male luer connector portion, a female luer connector portion, a tube, and an overmolded body portion. The male luer connector portion defies a first lumen. The female luer connector portion defines a second lumen. The tube defines a third lumen. The third lumen is in fluid communication with the first lumen and the second lumen. The third lumen has a diameter less than 0.025 inches. The overmolded body portion is formed around the tube.

Abstract: A flow restriction device may include a male luer connector portion and a female luer connector portion. The male luer connector portion can define a cavity and a first lumen in fluid-flow continuity with the cavity. The female luer connector portion defines a second lumen and an extension in fluid-flow continuity with the second lumen. The extension includes a first end, a second end, an outer surface, and a channel. The channel is defined on the outer surface. The channel is helically disposed around the outer surface of the extension and extends between the first and second ends. The extension is configured to be at least partially disposed within the cavity. The channel and the inner surface of the cavity define a fluid passage in fluid-flow continuity with the first lumen and the second lumen.

Abstract: Fluid clamps are described herein. A fluid clamp includes a clamp body and a rotating body. The clamp body includes a first and second valve element. Each valve element includes a valve extension portion and a valve end portion extending from the valve extension portion. The first and second valve elements are disposed opposite to each other to allow a tubing to pass between the first and second valve elements. The rotating body is rotatably coupled to the clamp body. The rotation of the rotating body moves the valve end portion of at least one of the first and second valve elements to adjust a flow rate through the tubing.

Abstract: A flow restriction device may include a housing and an insert body. The housing defines a first lumen, a second lumen, and a cavity disposed between the first lumen and the second lumen. The insert body can be disposed within the cavity. The insert body includes a first end, a second end, a longitudinal axis extending through the first and second ends, an outer surface, and a channel. The channel is defined on the outer surface. The channel extends between the first and second ends. The channel includes a first portion that extends in a first direction away from the longitudinal axis and a second portion that extends in a second direction toward the longitudinal axis. The channel and an inner surface of the cavity define a fluid passage in fluid communication with the first lumen and the second lumen.

Abstract: The device includes a housing, said housing defining an internal conduit for circulation of the medical fluid from a fluid inlet to a fluid outlet, a slider arranged inside the internal conduit such that the slider is movable along a central longitudinal axis A between an opening position, wherein the medical fluid is allowed to flow through the fluid outlet, and a closing position, wherein the medical fluid is prevented from flowing through said fluid outlet, a plug connected to the slider said plug being configured to close the fluid outlet when the slider is in the closing position, a resilient member disposed proximally to the plug and configured to exert a proximal force on said the slider such that the resilient member maintains the slider in the opening position, a proximally oriented pressure area provided on an actuation member of the slider, said pressure area being configured to cause the slider to reach the closing position against the action of the resilient member when the medical fluid pressure

Abstract: A flow restriction device may include a housing with first and second end portions forming respective first and second openings, and a cavity configured to receive an insert body defining a fluid passage that extends from a first opening of the housing at the first end portion to a second opening of the housing at the second end portion, where the fluid passage extends in more than one direction along a path between the first and second end portions of the housing to induce a resistance to a fluid flow moving through the device, thereby reducing a flow rate and pressure of the fluid, and where the fluid is blood, reduce the hemolysis index of the blood.

Abstract: A needle-free connector assembly is provided that includes a main housing coupled to an indicator housing. A plunger is coupled to a bellows disposed in the main housing. An inlet port is disposed at an upstream end of the indicator housing and an outlet port is disposed at a downstream end of the main housing, with a valve disposed within the indicator housing and adjacent the inlet port. A switch member is slidingly disposed in the main housing, wherein the needle-free connector assembly provides both flow regulation and pressure indication when the switch member is in a downstream position and only pressure indication when the switch member is in an upstream position. Infusion sets and methods of operating a needle-free connector are also provided.

Abstract: Needle covers having a clam-shell configuration configured to removably attach to a feature of a needle while the needle is inserted into the skin of a patient. The needle cover comprises a base having connecting feature, and a two-piece hinged cap connected to the base by two living hinges.

Abstract: A hard package assembly is disclosed having a cam mechanism for ejecting a syringe from a hard package container with the use of a single hand. The cam mechanism including a push button and a button retainer, the push button having a trapezoidal body having a button face, a distal face adjacent and distal to the button face and a sloped face opposite the button face, the button retainer having a proximal portion, a distal portion in contact with the sloped face of the push button and a distal hook in contact with a bottom surface of the barrel flange. A method of use and a method of assembly are also disclosed.

Abstract: A flow restriction device may include a proximal housing including an internal fluid channel, a distal housing including an internal fluid channel, and an intermediate housing interposed between the proximal and distal housings. The intermediate housing may include an internal chamber, and a slider reciprocally disposed in the internal chamber. The slider may include an internal fluid channel and a seal overlaying an outer surface of slider excluding the fluid channel, and may be reciprocally movable between (i) a first position where the internal fluid channel of the slider is axially aligned with the internal fluid channels of the proximal and distal housings to allow a fluid to flow therethrough, and (ii) a second position where the internal fluid channel of the slider is not aligned with the internal fluid channels of the proximal and distal housings and the seal blocks fluid connection between the proximal and distal housings.

Abstract: A levered flow regulation clamp assembly for adjusting the fluid flow rate in a connector tube of an infusion set is provided. The levered flow regulation clamp assembly includes a housing to receive the connector tube and a slider rotatably engaged within the housing and configured to compress the connector tube to provide a fluid flow adjustment. Infusion sets and methods of adjusting fluid flow rates are also provided.