Patents by Inventor Amir Pelleg

Amir Pelleg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Screening method for modulation of human mast cell
    Publication number: 20020055515
    Abstract: Human mast cell activation is modulated by ATP binding to P2-purinoceptors on the mast cell surface. ATP binding to the purinoceptors provides a target for therapeutic intervention for the treatment of disorders characterized by undesireable mast cell mediator release, such as asthma and allergy. Inhibitors of ATP binding to mast cell P2-purinoceptors are useful therapeutic agents for treatments of those disorders. Methods of treatment using agents, and in vitro screening assays for selection of the therapeutic agents, are described.
    Type: Application
    Filed: December 20, 2001
    Publication date: May 9, 2002
    Inventors: Amir Pelleg, Edward S. Schulman
  • Modulation of human mast cell activation
    Patent number: 6372724
    Abstract: Human mast cell activation is modulated by ATP binding to P2-purinoceptors on the mast cell surface. ATP binding to the purinoceptors provides a target for therapeutic intervention for the treatment of disorders characterized by undesirable mast cell mediator release, such as asthma and allergy. Inhibitors of ATP binding to mast cell P2-purinoceptors are useful therapeutic agents for treatment of those disorders. Methods of treatment using such agents, and in vitro screening assays for selection of the therapeutic agents, are described.
    Type: Grant
    Filed: December 2, 1999
    Date of Patent: April 16, 2002
    Assignee: Duska Scientific Co.
    Inventors: Amir Pelleg, Edward S. Schulman
  • Process for regulating vagal tone
    Patent number: 5874420
    Abstract: The present invention provides methods of altering vagal tone in a patient by administering a therapeutically effective amount of a mediator of P.sub.2x -purinoceptors located on vagal afferent nerve terminals to the patient. Diagnostic applications are also provided.
    Type: Grant
    Filed: December 23, 1996
    Date of Patent: February 23, 1999
    Assignee: Allegheny University of the Health Sciences
    Inventor: Amir Pelleg