Patents by Inventor Amit Pascal

Amit Pascal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10595722
    Abstract: Retinal imaging systems and related methods employ a user specific approach for controlling the reference arm length in an optical coherence tomography (OCT) imaging device. A method includes restraining a user's head relative to an OCT imaging device. A reference arm length adjustment module is controlled to vary a reference arm length to search a user specific range of reference arm lengths to identify a reference arm length for which the OCT image detector produces an OCT signal corresponding to the retina of the user. The user specific range of reference arm lengths covers a smaller range of reference arm lengths than a reference arm length adjustment range of the reference arm length adjustment module.
    Type: Grant
    Filed: May 28, 2019
    Date of Patent: March 24, 2020
    Assignee: Notal Vision Ltd.
    Inventors: Amit Pascal, Omer Rafaeli, Yair Alster, Gidon Goren-Gratzyani
  • Publication number: 20190274545
    Abstract: Ophthalmic imaging systems and related methods provide pseudo feedback to aid a user in aligning the user's eye with an optical axis of the imaging system. An ophthalmic imaging system includes an ophthalmic imaging device having an optical axis, a display device, an eye camera, and a control unit. The display device displays a fixation target viewable by the user. The eye camera images the eye to generate eye image data. The control unit processes the eye image data to determine a position of the eye relative to the optical axis, processes the position of the eye relative to the optical axis to generate a pseudo position of the eye relative to the optical axis, and causes the display device to display an indication that provides feedback to the user that the eye is located at the pseudo position of the eye relative to the optical axis.
    Type: Application
    Filed: May 29, 2019
    Publication date: September 12, 2019
    Inventors: Amit Pascal, Omer Rafaeli, Yair Alster, Gidon Goren-Gratzyani
  • Publication number: 20190254518
    Abstract: Ophthalmic imaging devices and related methods employ self-alignment of a user with an optical axis of the imaging device. An ophthalmic imaging device includes an imaging assembly having an optical axis, a housing assembly, and a viewer assembly. The housing assembly is configured to rest on a horizontal surface during operation of the imaging assembly. The optical axis is oriented at an angle from 45 degrees to 85 degrees from the horizontal surface. The viewer assembly includes an interface surface shaped to engage a user's head to stabilize a position and an orientation of the user's head relative to the optical axis. The viewer assembly accommodates different positions and/or orientations of the user's head relative to the optical axis so as to enable alignment, by the user, of one of the user's eyes with the optical axis.
    Type: Application
    Filed: May 6, 2019
    Publication date: August 22, 2019
    Inventors: Omer Rafaeli, Muki Rapp, Hanoch Gideon Benyamini, Yair Alster, Eitan Sharif, Amit Pascal
  • Publication number: 20180160950
    Abstract: A swallowable in-vivo device comprising a shell formed with at least one inlet extending across a shell wall and configured for allowing ingress of fluid at least into the shell; the shell accommodates therein a lateral flow (LF) arrangement configured for absorbing the fluid; the LF arrangement comprises a test zone configured for coming into contact, in-vivo, with a predetermined N substance present in the fluid or a compound comprising the substance, thereby causing a change in at least one property of the test zone; the shell further accommodates a sensor configured for sensing, in-vivo, the at least one property, at least when changed by interaction with the fluid; the LF arrangement has at least one curved segment, and at least one exposure portion juxtaposed with the inlet, configured for absorbing the fluid passing through the inlet into the shell.
    Type: Application
    Filed: June 2, 2016
    Publication date: June 14, 2018
    Applicant: GIVEN IMAGING LTD.
    Inventors: Elisha RABINOVITZ, Osnat SELLA-TAVOR, Amit PASCAL
  • Patent number: 9795330
    Abstract: In-vivo devices, systems and methods for the detection of blood within in-vivo bodily fluids. The methods include irradiating in-vivo fluids passing through a gap in a housing of an in-vivo device introduced to the GI tract of a subject with a plurality of illumination sources positioned on a first side of a gap; detecting with at least one light detector positioned on the opposite side of the gap and facing the illumination sources, light irradiated by the illumination sources; transmitting a plurality of values representing the light detected over time; converting these values to blood concentration values over time, and comparing the blood concentration values to a predetermined threshold value. Based on the comparison, the method includes determining the type of bleeding profile, such that if a plurality of blood concentration values measured consecutively is above the threshold value, the bleeding profile indicates bleeding.
    Type: Grant
    Filed: June 13, 2014
    Date of Patent: October 24, 2017
    Assignee: GIVEN IMAGING LTD.
    Inventors: Amit Pascal, Zvika Gilad, Elisha Rabinovitz, Yaniv Birnboim
  • Patent number: 9730573
    Abstract: An in-vivo imaging device for capturing one or more narrow band images of the gastrointestinal tract, or other body lumens or cavities of a patient, using one or more narrow band illumination sources and an imager having an array of light sensitive elements.
    Type: Grant
    Filed: March 20, 2007
    Date of Patent: August 15, 2017
    Assignee: GIVEN IMAGING LTD.
    Inventor: Amit Pascal
  • Patent number: 9615730
    Abstract: The invention provides a device for in-vivo imaging, for example, using an in-vivo imaging device including an imager a lens and an illumination source, all positioned behind a single viewing window. The in-vivo imaging device may include an element to block light from reaching a point of reflection on the inner surface of the viewing window, thereby preventing the light from being received by the imager.
    Type: Grant
    Filed: March 16, 2016
    Date of Patent: April 11, 2017
    Assignee: GIVEN IMAGING LTD.
    Inventors: Amit Pascal, Zvika Gilad, Haim Bezdin
  • Patent number: 9456737
    Abstract: An in-vivo imaging device and method for performing spectral analysis include inserting the in-vivo device into a patient's lumen, illuminating the tissue lumen and collecting the light scattered and reflected from the tissue. The device may comprise at least six illumination sources for illuminating the tissue. At least two of the six illumination sources illuminate at a different wavelength in the blue spectral region, at least two illuminate at a different wavelength in the green spectral region, and at least two illuminate at a different wavelength in the red spectral region. The illumination sources are adapted to illuminate in groups of three, wherein each group of three illumination sources comprises one illumination source that illuminates in the blue spectral region, one in the green spectral region, and one in the red spectral region. Each group of three illumination sources illuminates simultaneously.
    Type: Grant
    Filed: November 16, 2011
    Date of Patent: October 4, 2016
    Assignee: GIVEN IMAGING LTD.
    Inventor: Amit Pascal
  • Publication number: 20160192833
    Abstract: The invention provides a device for in-vivo imaging, for example, using an in-vivo imaging device including an imager a lens and an illumination source, all positioned behind a single viewing window. The in-vivo imaging device may include an element to block light from reaching a point of reflection on the inner surface of the viewing window, thereby preventing the light from being received by the imager.
    Type: Application
    Filed: March 16, 2016
    Publication date: July 7, 2016
    Applicant: GIVEN IMAGING LTD.
    Inventors: Amit PASCAL, Zvika GILAD, Haim BEZDIN
  • Patent number: 9360605
    Abstract: A system and method for acquiring images containing spatial and spectral information of an object include acquiring defocused images using an optical system based on extended depth of field. The optical system further includes a filter array comprising an array of at least six different sub-filters that are arranged such that any group of four immediately adjacent sub-filters includes at least one red sub-filter, at least one green sub-filter and at least one blue sub-filter. The filter array is located at the aperture stop of the optical system. A coded mask is located at the focal plane of the optical system, and an imager is located beyond the focal plane such that images acquired by the imager are defocused. The images are refocused, and spectral and spatial information is restored by designated software.
    Type: Grant
    Filed: January 17, 2013
    Date of Patent: June 7, 2016
    Assignee: GIVEN IMAGING LTD.
    Inventor: Amit Pascal
  • Patent number: 9339174
    Abstract: A device and method for viewing a body lumen are provided. An assembly of a capsule endoscope and an endoscope is inserted into a body lumen. The capsule endoscope is positioned within the body lumen at a predetermined distance from the endoscope, and images are obtained from opposite sides of a desired location in the body lumen. In vivo procedures may be performed, while images of the procedure are obtained from opposite sides of the procedure location.
    Type: Grant
    Filed: July 17, 2008
    Date of Patent: May 17, 2016
    Assignee: GIVEN IMAGING LTD
    Inventors: Zvika Gilad, Amit Pascal
  • Patent number: 9320417
    Abstract: The invention provides a device for in-vivo imaging, for example, using an in-vivo imaging device including an imager a lens and an illumination source, all positioned behind a single viewing window. The in-vivo imaging device may include an element to block light from reaching a point of reflection on the inner surface of the viewing window, thereby preventing the light from being received by the imager.
    Type: Grant
    Filed: December 27, 2006
    Date of Patent: April 26, 2016
    Assignee: GIVEN IMAGING LTD.
    Inventors: Amit Pascal, Zvika Gilad, Haim Bezdin
  • Patent number: 8911368
    Abstract: A device, system and method for detecting bile and blood are provided. The device may comprise a housing having a gap through which in-vivo fluids may flow, illumination sources on one side of the gap, a light detector which is facing the illumination sources and is positioned on the opposite side of the gap for detecting light which passes through the in-vivo fluids, and a transmitter to transmit the detected signals generated according to the detected light. The system may further comprise a receiver to receive the detected signals transmitted by the transmitter, and a processor. The method may comprise comparing the detected signals with a predetermined threshold calculated from the transmission spectra of bile and of blood and determining the presence and/or concentration of bile and blood in-vivo.
    Type: Grant
    Filed: January 31, 2010
    Date of Patent: December 16, 2014
    Assignee: Given Imaging, Ltd.
    Inventors: Elisha Rabinovitz, Amit Pascal, Ori Braun, Zvika Gilad, Osnat Sella-Tavor, Yaniv Birnboim
  • Publication number: 20140296666
    Abstract: In-vivo devices, systems and methods for the detection of blood within in-vivo bodily fluids. The methods include irradiating in-vivo fluids passing through a gap in a housing of an in-vivo device introduced to the GI tract of a subject with a plurality of illumination sources positioned on a first side of a gap; detecting with at least one light detector positioned on the opposite side of the gap and facing the illumination sources, light irradiated by the illumination sources; transmitting a plurality of values representing the light detected over time; converting these values to blood concentration values over time, and comparing the blood concentration values to a predetermined threshold value. Based on the comparison, the method includes determining the type of bleeding profile, such that if a plurality of blood concentration values measured consecutively is above the threshold value, the bleeding profile indicates bleeding.
    Type: Application
    Filed: June 13, 2014
    Publication date: October 2, 2014
    Inventors: ELISHA RABINOVITZ, Zvika GILAD, Amit PASCAL, Yaniv BIRNBOIM, Gavriel J. IDDAN, Daniel GAT, Hagai KRUPNIK, Ori BRAUN, Dan ROTTENBERG, Omer SHEZIFI, Yosi PESIS, Dima PINHASOV, Evgeny KAPILOV, Nir LILACH, Eliahu ELIACHAR, Oren COHEN, Daniel GAMZU
  • Publication number: 20140206956
    Abstract: In vivo devices, systems and methods for in vivo immunoassay include inserting into a patient's body lumen an in vivo diagnostic device comprising a housing. The housing of the device comprises a chamber, and a chromatography strip for immunoassay of a body lumen substance. The housing may further comprise a casing for the chromatography strip. The casing may comprise a first opening to allow entrance of in vivo liquids into the casing and a second opening into the chamber. The housing may further comprise a sensor to sense a property of the chromatography strip. Following insertion of the device into the patient's body, a sample is collected and the immunoassay is performed in vivo in areas of pathological lesions for a predetermined period of time. An in vivo image may be acquired or other data such as colorimetric or intensity data may be obtained from the chromatography strip.
    Type: Application
    Filed: August 1, 2012
    Publication date: July 24, 2014
    Inventors: Elisha Rabinovitz, Zvika Gilad, Osnat Sella-Tavor, Amit Pascal
  • Patent number: 8663092
    Abstract: A device, system and method for capturing in-vivo images allows for size or distance estimations for objects within the images. According to one embodiment of the present invention there may be provided, in an in-vivo device at least an imager, an illumination source to provide illumination for the imager, an energy source to emit for example a light beam or a laser beam in a body lumen and a processor to, based on the light beam or laser beam image, estimate, for example the size of objects in a body lumen.
    Type: Grant
    Filed: December 28, 2006
    Date of Patent: March 4, 2014
    Assignee: Given Imaging, Ltd.
    Inventors: Amit Pascal, Eli Horn
  • Patent number: 8639314
    Abstract: An in-vivo device, system and a method for imaging a body lumen, typically liquid filled body lumen. The in-vivo device may have a specific gravity of about 1 or a volume to weight ratio that enables it to float. The in-vivo device may include an optical system for viewing through a body lumen liquid and another optical system for viewing through a non liquid medium. The in-vivo device may be moved through the body lumen by the liquid movement in that lumen.
    Type: Grant
    Filed: November 23, 2005
    Date of Patent: January 28, 2014
    Assignee: Given Imaging Ltd.
    Inventors: Zvika Gilad, Amit Pascal
  • Publication number: 20130231536
    Abstract: An in-vivo imaging device and method for performing spectral analysis include inserting the in-vivo device into a patient's lumen, illuminating the tissue lumen and collecting the light scattered and reflected from the tissue. The device may comprise at least six illumination sources for illuminating the tissue. At least two of the six illumination sources illuminate at a different wavelength in the blue spectral region, at least two illuminate at a different wavelength in the green spectral region, and at least two illuminate at a different wavelength in the red spectral region. The illumination sources are adapted to illuminate in groups of three, wherein each group of three illumination sources comprises one illumination source that illuminates in the blue spectral region, one in the green spectral region, and one in the red spectral region. Each group of three illumination sources illuminates simultaneously.
    Type: Application
    Filed: November 16, 2011
    Publication date: September 5, 2013
    Inventor: Amit Pascal
  • Patent number: 8523788
    Abstract: An in-vivo examining device, system and method for identifying the presence of strictures in the small bowel are provided. The in-vivo examining device includes a monitoring mechanism that becomes deactivated when exposed to in-vivo substances native to the small bowel or the colon, and a degradable device body that includes at least a first body portion which degrades at a slow rate when exposed to in-vivo substances native to the small bowel and at a fast rate when exposed to in-vivo substances native to the colon. The degradation of the degradable device body exposes the monitoring mechanism to substances native to the small bowel or the colon and thus indicates whether the examining device has safely passed through the small bowel or whether it is retained in the small bowel due to strictures in the small bowel.
    Type: Grant
    Filed: August 5, 2010
    Date of Patent: September 3, 2013
    Assignee: Given Imaging Ltd.
    Inventors: Elisha Rabinovitz, Amit Pascal, Zvika Gilad, Daniel Afik
  • Patent number: 8515507
    Abstract: Devices, systems and methods for detecting in vivo pathology are provided. An in vivo sensing device comprises a reacting layer with at least one type of binding agent attached thereon, a sensor configured for sensing an optical change occurring on the reacting substrate, and at least one illumination source. In-vivo fluids are in constant contact with the reacting substrate so that in vivo marker indicating pathology may bind to the binding agent attached onto the reacting layer and may be viewed by the sensor.
    Type: Grant
    Filed: June 16, 2009
    Date of Patent: August 20, 2013
    Assignee: Given Imaging Ltd.
    Inventors: Elisha Rabinovitz, Osnat Sella-Tavor, Amit Pascal, Noam Emanuel