Patents by Inventor Amit Patel

Amit Patel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of Glioma by Amniotic Fluid Stem Cells and Exosomes Derived Thereof
    Publication number: 20190022147
    Abstract: Disclosed are compositions of matter, therapeutic protocols, and cellular reprogramming means to inhibit glioma or other brain neoplasia. In one embodiment the invention provides administration of amniotic fluid derived stem cells at concentrations of 1 million to 200 million administered in a manner to provide a differentiation stimulation, resulting in reduction of malignant potential. In other embodiments, an unexpected synergy of cancer inhibitory soluble factor production is disclosed by combined cultures between amniotic fluid stem cells and monocytes. In all embodiments cells may be autologous or allogeneic. The invention provides means of augmenting efficacy of immunotherapy, chemotherapy, and radiotherapy.
    Type: Application
    Filed: July 24, 2018
    Publication date: January 24, 2019
    Applicant: Creative Medical Technologies, Inc
    Inventors: Thomas Ichim, Amit Patel, Santosh Kesari
  • Perispinal Perfusion by Administration of T regulatory Cells Alone or in Combination with Angiogenic Cell Therapies
    Publication number: 20180360882
    Abstract: Disclosed are method of enhancing perispinal perfusion in a patient suffering from reduced perfusion of the lower back through administration of T regulatory cells alone capable of stimulating angiogenesis directly or through enhancement of angiogenic activities of cellular therapies. Said cellular therapies possessing angiogenic activities include mesenchymal stem cells, hematopoietic stem cells and endothelial progenitor cells. In one embodiment of the invention, administration of T regulatory cells is performed that are expanded ex vivo. For certain embodiment of the invention T regulatory cells may be autologous or allogeneic.
    Type: Application
    Filed: June 15, 2018
    Publication date: December 20, 2018
    Applicant: Creative Medical Technologies, Inc.
    Inventors: Thomas Ichim, Amit Patel
  • ENHANCEMENT OF NUCLEUS PULPOSUS REGENERATION BY ENHANCED PERFUSION OF PERISPINAL AREA BY COMBINATION DRUG, GENE AND CELLULAR THERAPIES
    Publication number: 20180344899
    Abstract: Disclosed are methods of enhancing regeneration of the nucleus pulposus through enhancement of perispinal perfusion in combination with a regenerative intervention. In one embodiment the invention teaches stimulation of enhancement of perispinal perfusion by administration of angiogenic agents prior to performing a regenerative intervention such as administration of a stem cell therapy. In one specific embodiment perispinal angiogenesis is stimulated by administration of autologous bone marrow mononuclear cells in the perispinal area, preferably into a muscular area, subsequent to which intradiscal administration of regenerative cells, such as mesenchymal stem cells is performed.
    Type: Application
    Filed: June 1, 2018
    Publication date: December 6, 2018
    Applicant: Creative Medical Technologies, Inc.
    Inventors: Thomas Ichim, Amit Patel, Donald Dickerson
  • GENERATION OF AUTOLOGOUS IMMUNE MODULATORY CELLS FOR TREATMENT OF NEUROLOGICAL CONDITIONS
    Publication number: 20180340145
    Abstract: Disclosed are means, methods, and compositions of matter useful for treatment of neuroinflammation, autoimmunity, transplant rejection, or graft versus host disease (GVHD) comprising exposing autologous immune cells to allogeneic amniotic fluid derived stem cells. In one embodiment peripheral blood mononuclear cells are cultured in the presence of amniotic fluid stem cells in the presence of interleukin-2 for a period of time sufficient to endow tolerogenic properties. Said tolerogenic properties include ability to suppress adaptive or innate immune responses. In another embodiment the invention provides methods of generating antigen specific immune regulatory cells by culture of lymphocytes together with amniotic fluid stem cells in the presence of antigen to which specific immune regulation is desired.
    Type: Application
    Filed: May 23, 2018
    Publication date: November 29, 2018
    Applicant: Creative Medical Technologies, Inc.
    Inventors: Thomas Ichim, Amit Patel
  • METHODS OF TREATING ERECTILE DYSFUNCTION
    Publication number: 20180325959
    Abstract: Therapies for treating erectile dysfunction using regenerative cells and therapeutic energy treatments are disclosed herein. Said therapeutic energy treatments can be selected from one or more of the following methods: electrical stimulation/electroacupuncture, low-level laser irradiation, and extracorporeal shockwave therapy. The combination treatments described herein are useful for restoring components of the penile anatomy that are associated with erectile dysfunction, in particular, nerves, blood vessels and/or smooth muscle cells.
    Type: Application
    Filed: May 9, 2017
    Publication date: November 15, 2018
    Inventors: Thomas ICHIM, Amit PATEL, Annette MARLEAU
  • USE OF UV RESISTANT ACTIVE MATERIALS ON HAIR
    Publication number: 20180263891
    Abstract: Polymers comprising at least one cationic functional group and at least one ultraviolet light-absorbing compound are disclosed herein. The resulting polymers exhibit ultraviolet light-absorbing properties and may be used in sunscreen compositions for skin and/or hair.
    Type: Application
    Filed: March 16, 2018
    Publication date: September 20, 2018
    Inventor: Amit Patel
  • Foam boosting saccharide blend
    Patent number: 10052274
    Abstract: Disclosed is a foam booster that is capable of producing or increasing the amount of foam in any given composition. The foam booster includes a saccharide blend having 30 wt. % to 50 wt. % of an aldohexose or mixture of aldohexoses, 20 wt. % to 55 wt. % of a ketohexose or mixture of ketohexoses; and 10 wt. % to 20 wt. % of a disaccharide or mixture of disaccharides.
    Type: Grant
    Filed: February 8, 2017
    Date of Patent: August 21, 2018
    Assignee: Coast Southwest Inc.
    Inventors: Shannon Smith Butz, Amit Patel
  • Stent with embedded pressure sensors
    Patent number: 9999528
    Abstract: A stent including a wire tube and at least one pressure sensor in electrical contact with the wire tube. The pressure sensor includes a diaphragm in communication with a reservoir of liquid, a channel in fluid communication with the reservoir of liquid, and at least one pair of electrodes disposed on opposite sides of the channel, wherein deflection of the diaphragm causes fluid to move from the reservoir into the channel.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: June 19, 2018
    Assignee: University of Utah Research Foundation
    Inventors: Hanseup Kim, Ashrafuzzaman Bulbul, Amit Patel, Anwar Tandar
  • PARTICULATE LYOPHILIZED PLATELET LYSATE COMPOSITIONS
    Publication number: 20180163172
    Abstract: A particulate lyophilized platelet lysate composition suitable for use as a cell culture medium can include growth factors, cytokines, and chemokines released from lysis of source platelets, wherein cellular debris from the source platelets is removed (partially or fully) by filtration. The growth factors, cytokines, and chemokines are lyophilized to form a particulate lyophilized platelet lysate composition.
    Type: Application
    Filed: May 31, 2016
    Publication date: June 14, 2018
    Inventor: Amit Patel
  • TREATMENT OF CACHEXIA USING STEM CELLS AND PRODUCTS THEREOF
    Publication number: 20180133258
    Abstract: The current invention teaches the use of cells possessing regenerative properties, tissues associated with said cells possessing regenerative properties, and products derived from cells possessing regenerative properties for the treatment of cachexia. In one embodiment, cancer or HIV associated cachexia is treated by administration of tissues possessing regenerative cells that have been modified to allow for administration in a manner which is intravenous, subcutaneous or intramuscular while retaining properties associated with cellular regeneration.
    Type: Application
    Filed: November 15, 2017
    Publication date: May 17, 2018
    Applicant: Creative Medical Health, LLC
    Inventors: Thomas Ichim, Amit Patel
  • Advanced Solder Alloys For Electronic Interconnects
    Publication number: 20180102464
    Abstract: Improved electrical and thermal properties of solder alloys are achieved by the use of micro-additives in solder alloys to engineer the electrical and thermal properties of the solder alloys and the properties of the reaction layers between the solder and the metal surfaces. The electrical and thermal conductivity of alloys and that of the reaction layers between the solder and the -metal surfaces can be controlled over a wide range of temperatures. The solder alloys produce stable microstructures wherein such stable microstructures of these alloys do not exhibit significant changes when exposed to changes in temperature, compared to traditional interconnect materials.
    Type: Application
    Filed: October 6, 2016
    Publication date: April 12, 2018
    Inventors: Morgana de Avila Ribas, Pritha Choudhury, Siuli Sarkar, Ranjit Pandher, Nicholas G. Herrick, Amit Patel, Ravindra M Bhatkal, Bawa Singh
  • TREATMENT OF STROKE BY AMNIOTIC FLUID DERIVED STEM CELL CONDITIONED MEDIA AND PRODUCTS DERIVED THEREOF
    Publication number: 20180085405
    Abstract: Disclosed are compositions of matter useful for treatment of stroke derived from amniotic fluid stem cell produced factors. In one embodiment the invention teaches the use of products derived from amniotic fluid stem cells cultured under basal conditions. In another embodiment the invention teaches the utilization of amniotic stem cell derived products from said amniotic stem cells cultured under conditions of stress. Said amniotic stem cell derived products include small molecules, proteins, peptides, conditioned media, microvesicles, including exosomes and apoptotic bodies. In one embodiment, the invention teaches administration of amniotic fluid stem cells that have been exposed to a stress condition.
    Type: Application
    Filed: September 27, 2017
    Publication date: March 29, 2018
    Applicant: Creative Medical Technologies, Inc.
    Inventors: Thomas Ichim, Amit Patel, Santosh Kesari
  • Stable three-phased emulsions
    Patent number: 9918912
    Abstract: Disclosed is a water-in-silicone emulsion comprising a discontinuous water phase, a continuous silicone phase, and a silicone polyglucoside containing emulsifier, wherein the discontinuous water phase does not include a salt.
    Type: Grant
    Filed: January 19, 2016
    Date of Patent: March 20, 2018
    Assignee: Mary Kay Inc.
    Inventor: Amit Patel
  • NAVIGATION SYSTEM WITH DEVICE OPERATION MECHANISM AND METHOD OF OPERATION THEREOF
    Publication number: 20180073890
    Abstract: A method of operation of a navigation system includes: determining a surrounding condition with a control unit for selecting an input source to capture a surrounding object; determining an operating context based on calculating an average stopped time meeting or exceeding a time threshold within the surrounding condition; determining a feature availability based on the operating context for restricting a device feature available on a device; and delivering an alert notification based on an object count below a count threshold for presenting on the device.
    Type: Application
    Filed: September 12, 2016
    Publication date: March 15, 2018
    Inventor: Amit Patel
  • INDUCING AND ACCELERATING POST-STROKE RECOVERY BY ADMINISTRATION OF AMNIOTIC FLUID DERIVED STEM CELLS
    Publication number: 20180071342
    Abstract: Disclosed are means of inducing and accelerating neurological recovery subsequent to a stroke through administration of amniotic fluid derived stem cells. In one embodiment stem cells are isolated from amniotic fluid and expanded under conditions allowing for expression of SSEA3, SSEA4, Tra1-60, Tra1-81, Tra2-54, Oct-4 and CD105. Said cells are subsequently administered into a patient having undergone a stroke, so as to induce direct regeneration (through transdifferentiation and replacement of neural tissue), as well as indirect regeneration (through production of growth factors that augment endogenous regenerative mechanisms while inhibiting degenerative mechanisms). In some embodiments factors produced by said amniotic fluid stem cells may be utilized instead of cells themselves. Said factors may include proteins, peptides, conditioned media, exosomes, or microvesicles.
    Type: Application
    Filed: September 12, 2017
    Publication date: March 15, 2018
    Applicant: Creative Medical Technologies, Inc.
    Inventors: Thomas Ichim, Amit Patel
  • METHODS FOR TREATMENT OF PREMATURE OVARIAN FAILURE AND OVARIAN AGING USING REGENERATIVE CELLS
    Publication number: 20180015127
    Abstract: This invention pertains to the field of ovarian aging and premature ovarian failure. Specifically, we herein disclose methods for treating these conditions using endothelial progenitor cells alone or in combination with mesenchymal stem cells.
    Type: Application
    Filed: July 17, 2017
    Publication date: January 18, 2018
    Applicant: Creative Medical Technologies, Inc.
    Inventors: Thomas Ichim, Amit Patel
  • ADIPOSE DERIVED IMMUNOMODULATORY CELLS FOR IMMUNOTHERAPY OF RECURRENT SPONTANEOUS ABORTIONS
    Publication number: 20170354686
    Abstract: Disclosed are means of treating spontaneous abortion utilizing cellular populations derived from autologous adipose tissue. In one embodiment the invention teaches the collection of stromal vascular fraction from women attempting to conceive, isolation of anti-abortigenic cells from said stromal vascular fraction, storing said cells, and administering said cells in early pregnancy or when conception is desired.
    Type: Application
    Filed: June 8, 2017
    Publication date: December 14, 2017
    Inventors: Thomas Ichim, Amit Patel
  • Outboard motor mount and side-mount accessory adapter
    Publication number: 20170349255
    Abstract: An outboard motor mount and side-mount accessory adapter to mount an outboard motor and an accessory to the transom of a boat wherein the outboard motor mount includes a transom mounting plate to secure the outboard motor mount to the transom and an adapter mounting plate extending outwardly from the transom mounting plate and wherein the side-mount accessory adapter includes a proximal side-mount adapter mounting plate coupled to the adapter mounting plate and a distal accessory mounting plate to support the accessory thereon.
    Type: Application
    Filed: June 3, 2016
    Publication date: December 7, 2017
    Inventors: Brian Drozdowski, Amit Patel
  • LYOPHILIZED PLATELET LYSATES
    Publication number: 20170348354
    Abstract: The present disclosure is drawn to compositions and methods of making and using lyophilized platelet lysates. Specifically, a method of preparing a composition suitable for therapeutic use or as a culture medium can comprise steps of concentrating platelets from a platelet source to form a platelet rich portion of the platelet source, and lysing the platelets in the platelet rich portion to form a plurality of lysates. An additional step includes lyophilizing the lysates to form lyophilized platelet lysates in a composition with released concentrations of available growth factors, cytokines, and chemokines. In one example, at 30%, by platelet count, of platelets from a platelet source can be lysed using this process.
    Type: Application
    Filed: May 16, 2017
    Publication date: December 7, 2017
    Inventor: Amit Patel
  • LYOPHILIZED PLATELET LYSATES
    Publication number: 20170348355
    Abstract: The present disclosure is drawn to compositions and methods of making and using lyophilized platelet lysates. Specifically, a method of preparing a composition suitable for therapeutic use or as a culture medium can comprise steps of concentrating platelets from a platelet source to form a platelet rich portion of the platelet source, and lysing the platelets in the platelet rich portion to form a plurality of lysates. An additional step includes lyophilizing the lysates to form lyophilized platelet lysates in a composition with released concentrations of available growth factors, cytokines, and chemokines. In one example, at 30%, by platelet count, of platelets from a platelet source can be lysed using this process.
    Type: Application
    Filed: May 16, 2017
    Publication date: December 7, 2017
    Inventor: Amit Patel