Abstract: Solid state forms of Ivosidenib, processes for preparation thereof, pharmaceutical compositions thereof, and uses thereof are disclosed.

Abstract: A logic block can be relocated without recompilation from a first area to a second area on a field-programmable gate array (FPGA) if the pattern of fabric tiles in the second area is the same as the pattern of fabric tiles in the first area, and if the two areas have the same dimensions. The design system runs synthesis, placement, and routing on a partition of a design at a first location, exports that partition to a persistent on-disk database, imports one or multiple copies of the partition into a larger design, and moves one or more of the copies from the first area to a target area in the larger design.

Abstract: Cargo-loaded vesicles and compositions comprising such vesicles for oral delivery are provided, wherein the vesicles comprise one or more components from milk purified vesicles. Methods for producing such cargo loaded vesicles are also provided.

Abstract: A solid composition for the preservation of food includes a source of potassium cations selected from at least one of potassium carbonate and potassium hydrogen carbonate; and at least one of a source of ascorbate ions and a source of isoascorbate ions, wherein the source of ascorbate ions is selected from at least one of ascorbic acid, a salt of ascorbic acid and acerola or from any other suitable ascorbic acid rich source, wherein the source of isoascorbate is selected from at least one of isoascorbic acid and a salt of isoascorbic acid, and wherein a molar ratio of potassium cations to ascorbate anions and/or potassium cations to isoascorbate anions in the solid composition is within the range from 1.00:0.95 to 1.00:0.50, preferably 1.00: ?0.78 to 1.00:0.50.

Abstract: A device capable of autonomous motion may move in an environment and may receive audio data from a microphone. A model may be trained to process the audio data to determine mask data, which may be used to mask noise in the audio data. Training data for the model may be normalized before training, and different loss functions may be used for different types of training data.

Abstract: The systems, devices, and processes described herein may identify a beam of a voice-controlled device that is directed toward a reflective surface, such as a wall. The beams may be created by a beamformer. An acoustic echo canceller (AEC) may create filter coefficients for a reference sound. The filter coefficients may be analyzed to identify beams that include multiple peaks. The multiple peaks may indicate presence of one or more reflective surfaces. Using the amplitude and the time delay between the peaks, the device may determine that it is close to a reflective surface in a direction of the beam.

Abstract: The present disclosure encompasses solid state forms of Avapritinib, in embodiment crystalline polymorphs of Avapritinib, processes for preparation thereof, and pharmaceutical compositions thereof.

Abstract: The present disclosure relates to safe and efficient processes for the synthesis of Glasdegib or salts thereof, preferably Glasdegib Maleate. The present disclosure also encompasses solid state forms of Glasdegib maleate, in embodiments crystalline polymorphs of Glasdegib maleate, processes for preparation thereof, and pharmaceutical compositions thereof.

Abstract: A method for configuring a digital light projector (DLP) of an augmented reality (AR) display device is described. A light source component of the DLP projector is configured to generate a single red-green-blue color sequence repetition per image frame. The AR display device identifies a color sequence of the light source component of the DLP projector and tracks a motion of the AR display device. The AR display device adjusts an operation of the DLP projector based on the single red-green-blue color sequence repetition, the color sequence of the light source component of the DLP projector, and the motion of the AR display device.

Abstract: The present disclosure encompasses solid state forms of Avasopasem manganese, in embodiments crystalline polymorphs of Avasopasem manganese, processes for preparation thereof, and pharmaceutical compositions thereof.

Abstract: A lightweight stacked optical waveguide using two plastic substrates having nano-structure gratings and a single glass substrate sandwiched between them. The nano-structure gratings face each other, and are each encapsulated within the optical waveguide. The two plastic substrates are each adhesively secured to the central glass substrate rather than to each other to provide sufficient securing strength and precisely establish and maintain an air gap between the substrates. The thickness of the plastic substrates and the glass substrate are selected such that the stacked optical waveguide is lightweight, but also has sufficient drop performance. The stacked optical waveguide can be efficiently manufactured as the adhesive bonds a plastic substrate to a glass substrate.

Abstract: This application discloses a computing system implementing a power estimator can read in waveform data generated during functional verification of a circuit design describing an electronic device, detect toggles in the signals of the waveform data, correlate the detected toggles in the signals to arcs associated with logic gates in the circuit design, and track a number of times each of the arcs has been correlated to the detected toggles. After the waveform data has been read, the power estimator can look-up power values for each arc having been correlated to a detected signal toggle, multiple the power values by the tracked number of times each of the arcs been correlated to the detected toggles to compute power estimates, and generate an estimate of power consumption for the circuit design during the functional verification by accumulating the power estimates for the arcs associated with the logic gates.

Abstract: A system and method for positioning a sensor on a subject. In some embodiments, the system includes an instrument holder, the instrument holder being configured to be secured to a subject, and to hold an instrument temporarily.

Abstract: To provide a low latency near RT RIC, some embodiments separate the RIC's functions into several different components that operate on different machines (e.g., execute on VMs or Pods) operating on the same host computer or different host computers. Some embodiments also provide high speed interfaces between these machines. Some or all of these interfaces operate in non-blocking, lockless manner in order to ensure that critical near RT RIC operations (e.g., datapath processes) are not delayed due to multiple requests causing one or more components to stall. In addition, each of these RIC components also has an internal architecture that is designed to operate in a non-blocking manner so that no one process of a component can block the operation of another process of the component. All of these low latency features allow the near RT RIC to serve as a high speed IO between the E2 nodes and the xApps.

Abstract: The present invention provides shortening TB Therapy and reducing relapse by co-administering Chloroquine with anti-TB drugs to drug-sensitive TB patients, multiple drug resistant (MDR) TB patients and TB patients co-infected with HIV-1. The present invention also provides shortening TB Therapy and reducing relapse by co-administering hydroxychloroquine with anti-TB drugs to drug-sensitive TB patients, multiple drug resistant (MDR) TB patients and TB patients co-infected with HIV-1.

Abstract: An optoelectronic device. The device comprising: a silicon-on-insulator, SOI, wafer, the SOI wafer including a cavity and an input waveguide, the input waveguide being optically coupled into the cavity; and a mirror, located within the cavity and bonded to a bed thereof, the mirror including a reflector configured to reflect light received from the input waveguide in the SOI wafer.

Abstract: A computing device may receive audio data from a microphone representing audio in an environment of the device, which may correspond to an utterance and noise. A model may be trained to process the audio data to cancel noise from the audio data. The model may include an encoder that includes one or more dense layers, one or more recurrent layers, and a decoder that includes one or more dense layers.

Abstract: The present disclosure encompasses solid state forms of Setogepram, in embodiments crystalline polymorphs or salts of Setogepram, particularly Setogepram sodium, processes for preparation thereof, and pharmaceutical compositions thereof.

Abstract: A mirror and method of fabricating the mirror, the method comprising: providing a silicon-on-insulator substrate, the substrate comprising: a silicon support layer; a buried oxide (BOX) layer on top of the silicon support layer; and a silicon device layer on top of the BOX layer; creating a via in the silicon device layer, the via extending to the BOX layer; etching away a portion of the BOX layer starting at the via and extending laterally away from the via in a first direction to create a channel between the silicon device layer and silicon support layer; applying an anisotropic etch via the channel to regions of the silicon device layer and silicon support layer adjacent to the channel; the anisotropic etch following an orientation plane of the silicon device layer and silicon support layer to create a cavity underneath an overhanging portion of the silicon device layer; the overhanging portion defining a planar underside surface for vertically coupling light into and out of the silicon device layer; and

Abstract: Eyewear having electrochromic lenses for controlling a light transmissive property/tinting for a user's eye and a camera. The electrochromic lenses have an eye region for controlling light transmission to a user's eye, and a separate camera region for controlling light transmission to a camera. Two or more electrochromic lenses are provided to independently control the tinting for each of the user's eye, and two or more cameras. The electrochromic lenses comprise of multiple lens layers forming a single stack. Each layer has an opening configured to receive a fill material, such as a dye, such that the fill material can have different chemistries. The displays may also have different dye chemistries to allow for different tint ranges (wavelengths of light passed).