Abstract: Described herein are polymer formulations for facilitating electrical stimulation of nasal or sinus tissue. The polymer formulations may be hydrogels that are prepared by a UV cross-linking process. The hydrogels may be included as a component of nasal stimulator devices that electrically stimulate the lacrimal gland to improve tear production and treat dry eye. Additionally, devices and methods for manufacturing the nasal stimulators, including shaping of the hydrogel, are described herein.

Abstract: An electro-active optical cell is described including a layer of electro-active material, a front glass substrate member, and a back glass substrate member. The optical cell is capable of independently providing changeable optical power with the application of an electrical potential. The cell is also configured to be affixed to an external surface of a plastic substrate and to provide the changeable optical power, with at least one of the front substrate or the back substrate of the optical cell being an outermost optical layer. The layer of electro-active material may have a thickness less than 10 ?m, and the glass substrate members may each have a thickness approximately between 20 ?m and 500 ?m.

Abstract: Many modern implantable ophthalmic devices include electronic components, such as electro-active cells, that can leak harmful substances into the eye and/or surrounding tissue. In the implantable ophthalmic devices disclosed herein, electronic components are hermetically sealed within cavities formed by bonding together two or more glass wafers. Bonding the glass wafers together with laser fusion bonding, pressure bonding, or anodic bonding creates a seal that leaks at a rate of less than about 5×10?12 Pa m3s?1 when subjected to a helium leak test. Hermetically sealed feedthroughs formed of conductive material running through channels in the wafers provide electrical connections to components inside the sealed cavities. In some cases, the conductive material has a coefficient of thermal expansion (CTE) that is roughly equal to (e.g., within 10% of) the CTE of the glass wafers to minimize leakage due to thermally induced expansion and contraction of the conductive material and the glass wafer.

Abstract: A variable focus optical apparatus including a rigid, curved, transparent optical component; two transparent, distensible membranes attached to a periphery of the rigid optical component to define two cavities, a first cavity between the rigid optical component and a first membrane and a second cavity between the first membrane and a second membrane; and a variable amount of fluid filling each of the cavities, and a reservoir containing additional fluid and in fluid communication with the cavity, wherein the reservoir is configured to provide injection of fluid into the cavity or withdrawal of fluid out of the cavity in response to a force or an impulse.

Abstract: A fluid lens assembly including a front rigid lens, a semi-flexible membrane that is adapted to be expanded from a minimum inflation level to a maximum inflation level, and a fluid layer therebetween. The front lens of the fluid lens assembly is configured to have a negative optical power. In an embodiment, the fluid lens assembly may be configured to have an overall negative optical power when the membrane is expanded to the maximum inflation level. In an embodiment, the fluid lens assembly can be configured to have an overall negative optical power when the membrane is expanded between the minimum inflation level and the maximum inflation level.

Abstract: Aspects of the present invention provide a lens comprising a non-rotationally symmetric aspheric optical element, surface or feature and a rotationally symmetric aspheric optical element, surface or feature. The non-rotationally symmetric aspheric optical feature can be a progressive power region. The non-rotationally symmetric aspheric optical feature and rotationally symmetric aspheric optical feature can be in optical communication when located on different surfaces of a lens or can be collapsed to occupy a single surface of a lens. The non-rotationally symmetric aspheric optical feature and rotationally symmetric aspheric optical feature can each contribute to the add power of a lens. Distortion (e.g., astigmatism) of a lens of the present invention can be reduced (e.g., globally and/or locally) by optically combing the non-rotationally symmetric aspheric optical feature with the rotationally symmetric aspheric optical feature.

Abstract: Many modern implantable ophthalmic devices include electronic components, such as electro-active cells, that can leak harmful substances into the eye and/or surrounding tissue. In the implantable ophthalmic devices disclosed herein, electronic components are hermetically scaled within cavities formed by bonding together two or more glass wafers. Bonding the glass wafers together with laser fusion bonding, pressure bonding, or anodic bonding creates a seal that leaks at a rate of less than about 5×10?12 Pa m3 s?1 when subjected to a helium leak test. Hermetically sealed feedthroughs formed of conductive material running through channels in the wafers provide electrical connections to components inside the sealed cavities. In some cases, the conductive material has a coefficient of thermal expansion (CTE) that is roughly equal to (e.g., within 10% of) the CTE of the glass wafers to minimize leakage due to thermally induced expansion and contraction of the conductive material and the glass wafer.

Abstract: Systems and methods of the disclosure relate to managing power consumption of an implantable device, such as an implantable ophthalmic device, that includes one or more rechargeable batteries and a processor operably coupled to the rechargeable batteries. The processor can be configured to implement a quick-charge process that includes charging each rechargeable battery for a first time interval using a first constant current, for a second time interval using a second constant current less than the first constant current, and for a third time interval using a constant voltage. This quick charge process is faster than conventional charging. The processor also manages discharge of two batteries in an alternating fashion so as to increase time between charging cycles, reduce the total number of charging cycles, and extend battery life.

Abstract: In an embodiment, a hinge for a fluid-filled. lens assembly includes a base having a first end configured to connect to a temple arm of the lens assembly and a second end configured to connect to a frame of the lens assembly, wherein the base includes a gap that is shaped to allow for tubing to pass from the first end to the second end of the base. In an embodiment, the first end of the base includes a cammed surface configured to engage a surface of the temple arm. In an embodiment, the first and second ends of the base are configured to flex around a rotation axis of the hinge.

Abstract: The invention relates to method for bonding at least two substrates, for example made from glass, silicon, ceramic, aluminum, or boron, by using an intermediate thin film metal layer for providing the bonding, said method comprising the following steps of: a) providing said two substrates; b) depositing said thin film metal layer on at least a part of a surface of a first substrate of the two substrates; c) bringing a surface of the second substrate into contact with said thin film metal layer on said surface of the first substrate such that a bonding between the second substrate and the thin film metal layer on the first substrate is provided; and d) at least locally strengthening the bonding between the second substrate and the thin film metal layer on the first substrate. The invention also relates to a device comprising two substrates, for example made from glass, silicon, ceramic, aluminum, or boron, and an intermediate thin film metal layer.

Abstract: Devices and methods related generally to electrochromic materials and their use. In some embodiments, the electrochromic materials are for use on an optical substrate, such as a lens, a semi-finished lens blank, and the like. Some embodiments include an electrochromic stack including nanostructured materials. Some embodiments include an electrochromic stack including nanostructured electrochromic materials. Some embodiments include one or more ion-conducting layers. Methods of making electrochromic stacks having nanostructured materials and/or ion-conducting layers are also discussed.

Abstract: In an embodiment, a hinge for a fluid-filled lens assembly includes a base having a first end configured to connect to a temple arm of the lens assembly and a second end configured to connect to a frame of the lens assembly, wherein the base includes a gap that is shaped to allow for tubing to pass from the first end to the second end of the base. In an embodiment, the first end of the base includes a cammed surface configured to engage a surface of the temple arm. In an embodiment, the first and second ends of the base are configured to flex around a rotation axis of the hinge.

Abstract: A wrist implant requires minimal resection of the distal radius and preserves the sigmoid notch and articulation with the head of the distal ulna. The wrist implant generally includes a radius portion, a carpal portion and a carpal ball. The wrist implant includes a primary articulation and a secondary rotational articulation. The primary articulation occurs between the radius portion and the carpal ball. The secondary articulation occurs between the carpal ball and the carpal portion.

Abstract: A non-round fluid lens assembly includes a non-round rigid lens and a flexible membrane attached to the non-round rigid lens, such that a cavity is formed between the non-round rigid lens and the flexible membrane. A reservoir in fluid communication with the cavity allows a fluid to be transferred into and out of the cavity so as to change the optical power of the fluid lens assembly. In an embodiment, a front surface of the non-round rigid lens is aspheric. Additionally or alternatively, a thickness of the flexible membrane may be contoured so that it changes shape in a spheric manner when fluid is transferred between the cavity and the reservoir.

Abstract: An optical and mechanical design of a sealed, non-round fluid-filled lens capable of providing variation of optical power. The fluid lens includes at least three optical components: at least one mostly rigid optical disc, at least one mostly flexible optical membrane and a layer of a transparent fluid that is in communication via a fluid channel with a reservoir of excess fluid contained in a reservoir that can be accessed to augment the fluid volume inside the fluid lens to change the power of the fluid lens. The fluid lens is capable of providing correction of spherical and astigmatic errors, and utilizes contoured membranes to provide for a substantially constant desired spherical power over a substantially full field of view of a user.

Abstract: An actuator for a fluid-filled lens including a housing having a first and second end; a reservoir disposed within the housing is disclosed. In an embodiment, the actuator further includes a compression arm having a first end that is fixed at a pivot and a second end that is not fixed such that the compression arm flexes to compress the reservoir.

Abstract: A non-round fluid lens assembly includes a non-round rigid lens and a flexible membrane attached to the non-round rigid lens, such that a cavity is formed between the non-round rigid lens and the flexible membrane. A reservoir in fluid communication with the cavity allows a fluid to be transferred into and out of the cavity so as to change the optical power of the fluid lens assembly. In an embodiment, a front surface of the non-round rigid lens is aspheric. Additionally or alternatively, a thickness of the flexible membrane may be contoured so that it changes shape in a spheric manner when fluid is transferred between the cavity and the reservoir.

Abstract: A wrist implant requires minimal resection of the distal radius and preserves the sigmoid notch and articulation with the head of the distal ulna. The wrist implant generally includes a radius portion, a carpal portion and a carpal ball. The wrist implant includes a primary articulation and a secondary rotational articulation. The primary articulation occurs between the radius portion and the carpal ball. The secondary articulation occurs between the carpal ball and the carpal portion.

Abstract: Aspects of the present invention provide an ophthalmic lens comprising at least one regressive and at least one non-regressive rotationally symmetric optical design element. The regressive and non-regressive optical design elements can be combined so as to form a desired optical power profile for the lens while simultaneously exploiting the different relative orientation of the astigmatic vectors of the constituent regressive and non-regressive design elements, thereby resulting in reduced unwanted astigmatism. The regressive and non-regressive rotationally symmetric optical design elements can be positioned on different lens surfaces and in optical communication or can be collapsed onto the same lens surface. The regressive and non-regressive rotationally symmetric optical design elements can each contribute to the total add power of an ophthalmic lens.

Abstract: An actuator for a fluid-filled lens including a housing having a first and a second end; a reservoir disposed within the housing. In an embodiment, a slider is slidingly disposed within the housing and disposed adjacent to the reservoir. In an embodiment, the actuator further includes a compression arm having a first end that is fixed and a second end that is not fixed, wherein the compression arm is disposed adjacent to the reservoir. Sliding the slider from one end of the housing to the other causes the slider to push the second end of the compression arm so as to compress the reservoir. In an embodiment, the slider includes a first end having a wedge shape configured to compress the reservoir. Sliding of the slider from one end of the housing to the other causes the first end of the slider to compress the reservoir.