Abstract: The present disclosure relates to bifunctional compounds, which find utility as modulators of enhancer of zeste homolog 2 (target protein). In particular, the present disclosure is directed to bifunctional compounds, which contain on one end a Von Hippel-Lindau, cereblon, Inhibitors of Apotosis Proteins or mouse double-minute homolog 2 ligand which binds to the respective E3 ubiquitin ligase and on the other end a moiety which binds the target protein, such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of target protein. The present disclosure exhibits a broad range of pharmacological activities associated with degradation/inhibition of target protein. Diseases or disorders that result from aggregation or accumulation of the target protein are treated or prevented with compounds and compositions of the present disclosure.

Abstract: An integrated circuit (IC) structure includes a long channel (LC) gate structure over a long channel region, the LC gate structure having a first gate height; and a short channel (SC) gate structure over a short channel region, the SC gate structure having a second gate height. The short channel region is shorter in length than the long channel region. The second gate height of the SC gate structure is no larger than the first gate height of the LC gate structure.

Abstract: The present invention provides methods for regulating plant architecture, improving biomass yield or regrowth after cutting through down-regulation of SPL4 gene function. Also provided are transgenic plants with improved biomass yield or regrowth after cutting produced by such methods.

Abstract: Devices, systems and methods for sub-block based prediction are described. In a representative aspect, a method for video processing includes partitioning a first component of a current video block into a first set of sub-blocks and partitioning a second component of the current video block into a second set of sub-blocks. A sub-block of the second component corresponds to one or more sub-blocks of the first component. The method also includes deriving, based on a color format of the current video block, motion vectors for a sub-block of the second component based on motion vectors for one or more corresponding sub-blocks of the first color component.

Abstract: A method of storing remote sensing big data in a Hbase database. The method includes: obtaining a remote sensing image, and pre-cropping the remote sensing image based on a Google S2 algorithm; selecting a grid level based on a resolution of the remote sensing image; demarcating a coverage scope of the remote sensing image; calculating grids covered within the coverage scope; cropping the remote sensing image according to the grids, to yield a plurality of image blocks, and serializing the plurality of image blocks; establishing an Hbase table; establishing a table storage model containing RowKey, and calculating the RowKey according to attributes of an image block; and integrating data structure of multi-source remote sensing image data according to attribute expression of a zoned remote sensing image in a plurality of dimensions, and storing serialized image blocks in an Hbase database according to the RowKey.

Abstract: A device is provided. The device includes a first lens assembly controllable to switch between a first plurality of optical powers. The first lens assembly includes a plurality of directly optically coupled lenses. The device also includes a second lens assembly controllable to switch between a second plurality of optical powers that are the opposite of the first plurality of optical powers. The device further includes a half-wave plate disposed between the first adaptive lens assembly and the second adaptive lens assembly.

Abstract: The present invention provides for novel fucosidase mutants that server as fuco-ligases for core fucosylation of a range of biological glycopeptides and glycoproteins including intact therapeutic antibodies. Several mutants with mutation at the general acid/base residue E274 of the Lactobacillus casei ?1,6-fucosidase, including E274A, E274S, and E274G, were able to efficiently fucosylate a wide variety of complex N-glycopeptides and intact glycoproteins. The site specific mutants enable the transfer of fucose to a core GlcNAc-Asn residue and useful for drug delivery and vaccine development.

Abstract: The present disclosure relates to a semiconductor device having a backside source/drain contact, and method for forming the device. The semiconductor device includes a source/drain feature having a top surface and a bottom surface, a first silicide layer formed in contact with the top surface of the source/drain feature, a first conductive feature formed on the first silicide layer, and a second conductive feature having a body portion and a first sidewall portion extending from the body portion, wherein the body portion is below the bottom surface of the source/drain feature, and the first sidewall portion is in contact with the first conductive feature.

Abstract: Computer-implemented methods, computer program products, and system facilitating evaluation of a progress of a diagnosis process are provided. The computer-implemented method comprises: obtaining, by a device operatively coupled to one or more processing units, a list of symptom(s); retrieving, by the device, a sub-graph associated with the list of symptom(s) from a knowledge graph; extracting, by the device, a list of feature(s) from the retrieved sub-graph; estimating, by the device, an average number of inquiries based on the extracted list of feature(s); and calculating, by the device, the progress of the diagnosis process based on the estimated average number of inquiries.

Abstract: The present disclosure relates to flexible-Ethernet data processing methods and devices. One example method includes acquiring a to-be-switched first client service flow, where the first client service flow is a service flow suitable for transmission on a flexible Ethernet, performing first rate adaptation from a source clock domain to a target clock domain on the first client service flow to obtain a second client service flow that matches the target clock domain, and performing serial-to-parallel conversion on the second client service flow in the target clock domain to obtain a parallel client slot flow.

Abstract: A fabric item may have control circuitry and input-output devices. A fabric haptic output device may be formed in the fabric item. The fabric haptic output device may be based on an electromagnetic fabric actuator, a piezoelectric fabric actuator, or other actuator formed from fabric. The fabric actuator may have a permanent magnet portion and an electromagnet portion. During operation, signals supplied to a coil in the electromagnet portion may create a magnetic field that moves the permanent magnet portion. Fabric support structures may be used to support an electromagnet or permanent magnet. Fabric springs may be coupled between the fabric support structures and the electromagnet or permanent magnet. The fabric of the support structures, magnetic structures, and springs may be incorporated into a wearable fabric structure, part of a cover or case for a device, a housing structure such as a housing wall, or other fabric structure.

Abstract: A radiation element, as well as an antenna unit and an antenna array thereof. The radiation element includes a metal radiation sheet, a plastic support structure, and a feeding balun. The antenna unit further includes a feeding network. Laser Direct Structuring (LDS) technology is used to manufacture the radiation element, the antenna unit and the antenna array thereof, eliminating metal reflection sheets; further surface mount technology (SMT) is employed to weld the antenna unit and the feeding network together, the antenna being light-weight and simple to assemble.

Abstract: This invention relates to the field of plastic waste decomposition. More specifically, the invention comprises products obtained from the decomposition of plastic waste.

Abstract: A method for manufacturing an integrated circuit is provided. The method includes depositing a floating gate electrode film over a semiconductor substrate; patterning the floating gate electrode film into at least one floating gate electrode having at least one opening therein; depositing a control gate electrode film over the semiconductor substrate to overfill the at least one opening of the floating gate electrode; and patterning the control gate electrode film into at least one control gate electrode over the floating gate electrode.

Abstract: Disclosed herein are extracts of Andrographis paniculata having highly concentrated active ingredients, preparation methods and medical use for treating autoimmunity and inflammatory disease.

Abstract: In accordance with at least selected embodiments, novel or improved separator membranes, separators, batteries including such separators, methods of making such membranes and/or separators, and/or methods of using such membranes and/or separators are disclosed or provided. In accordance with at least certain embodiments, an ionized radiation treated microporous polyolefin, polyethylene (PE), copolymer, and/or polymer blend (e.g., a copolymer or blend comprising PE and another polymer, such as polypropylene (PP)) battery separator for a secondary or rechargeable lithium battery and/or a method of making an ionized radiation treated microporous battery separator is disclosed.

Abstract: Techniques that facilitate improving an efficiency of a neural network are described. In one embodiment, a system is provided that comprises a memory that stores computer-executable components and a processor that executes computer-executable components stored in the memory. In one implementation, the computer-executable components comprise an initialization component that selects an initial value of an output limit, wherein the output limit indicates a range for an output of an activation function of a neural network. The computer-executable components further comprise a training component that modifies the initial value of the output limit during training to a second value of the output limit, the second value of the output limit being provided as a parameter to the activation function. The computer-executable components further comprise an activation function component that determines the output of the activation function based on the second value of the output limit as the parameter.

Abstract: A terminal is disclosed including a transmitter and a processor. The transmitter transmits uplink control information in an uplink control channel. The processor uses either a first uplink control channel format using a cyclic shift that depends on the uplink control information or a second uplink control channel format not using the cyclic shift that depends on the uplink control information, to transmit the uplink control information, based on a number of bits of the uplink control information and a type of the uplink control information. In other aspects, a radio communication method for a terminal is also disclosed.

Abstract: A circuit and method for establishing a balanced negative voltage to a near-end and far-end of a bitline having a plurality of memory cells connected to the bitline is disclosed. A MOS capacitor and a metal capacitor are connected in parallel. The MOS capacitor is connected to the near-end of the bitline through a first switch transistor. The metal capacitor is connected to the near-end of the bitline through the first switch transistor and the far end of the bitline through a second switch transistor. A falling negative boost voltage is applied to the MOS capacitor and the metal capacitor. When the switch transistors are turned on during a write operation, the MOS capacitor and the metal capacitor are both coupled to the voltage at the near-end and far-end and drive the voltage to approximately equal the boost voltage, thereby providing a balanced voltage to the bitline.

Abstract: A video processing method is provided to include determining, for a current video block of a video, a final prediction block for the current video block by refining one or more initial predictions for the current video block using an optical flow calculation based on a gradient of initial prediction samples according to a precision rule; and performing a conversion between the current video block and a coded representation using the final prediction block, wherein the optical flow calculation includes a prediction refinement with optical flow (PROF) procedure or a bi-directional optical flow (BDOF) procedure, wherein the precision rule specifies to use a same precision for representing the gradient for both the PROF procedure and the BDOF procedure.