Abstract: The present invention relates to a sunscreen composition, which comprises 5 to 50% by weight of at least one UV protective agent; 0.05 to 5% by weight of at least one hydrophobically modified clay mineral; 1 to 60% by weight of at least one oil component; and 0.1 to 4% by weight of at least one associative polymer. The present invention also provide a method of achieving an improved sunscreen protection effect with desirable film morphology and excellent wear properties.

Abstract: A full-electric drive cementing control system is disclosed.

Abstract: The spray dried plasma by the nature of its characteristics and the process by which it is made allows for a dried plasma with reduced pathogens. It has at least three aspects of pathogen reduction that results in a plasma product with reduced or no pathogens. The first aspect relates to a spray drying disposable and machine that eliminates or minimizes the introduction of pathogens into the spray drying process and is referred to as the anti-contamination process. The second aspect of pathogen reduction relates to the spray drying process and parameters that reduces pathogens that may be present in the donor plasma, and/or inhibit pathogen growth and/or pathogen proliferation introduced by the donor plasma. The third aspect results in reduced pathogens occurring during storage of the dried plasma wherein the manufacturing and storage conditions are such that pathogens are reduced, and/or pathogen growth and/or pathogen proliferation are inhibited.

Abstract: A protective film that can be included in multi-layer film laminates for use in marketing, advertising campaigns, particularly outdoor or other environment impacted promotions and safety applications. The film includes at least two different polyurethane polymers and is free or substantially free of polyvinyl chloride based polymer. One polyurethane has an ultimate elongation less than 200%, and another polyurethane has an ultimate elongation more than 400%. The film may be transparent, translucent, clear or have other desirable optical properties.

Abstract: The present invention relates to a spray dried plasma composition having one or more of the following characteristics: when reconstituted, largely amorphous and has no cholesterol crystals; when reconstituted, the mean size of large particulates is reduced; has low residual moisture; reconstitutes rapidly in under four minutes; highly stable when stored under refrigeration, at room temperature or at elevated temperatures and allows for storage for longer periods of time; when reconstituted, exhibits recovery of the most fragile of proteins, including von Willebrand's factor; when reconstituted with Sterile Water for Injection (SWFI), reconstituted plasma is at a pH that is near normal plasma pH, and does so without treatment or storage in CO2 or other pH adjustment.

Abstract: A tetravalent dengue inactivated vaccine is provided, including a DENV-1 inactivated antigen, a DENV-2 inactivated antigen, a DENV-3 inactivated antigen, and a DENV-4 inactivated antigen. The tetravalent dengue inactivated vaccine with a good immune effect is prepared by using four serotypes of dengue viruses as virus seeds. Furthermore, the tetravalent dengue inactivated vaccine is capable of being preserved at 4° C. for a long time, possesses lasting and effective immunogenicity, produces higher antibody titer in mice and non-human primates, has good challenge protection capability on suckling mice, has no reproductive toxicity in the mice, and has good safety.

Abstract: Provided is a traditional Chinese herbal composition for treating pulmonary nodules, a preparation method thereof, and a honeyed pill. The composition comprises: 30 parts by weight of Ziziphi Spinosae Semen, 20-30 parts by weight of Rehmaniae Radix, 30 parts by weight of Trichosanthis Radix, 40-50 parts by weight of Paeoniae Radix Alba, 30 parts by weight of Coicis Semen Preparata, 20 parts by weight of Ginseng Radix et Rhizoma, 10 parts by weight of Olibanum, 10 parts by weight of Myrrha, 20-30 parts by weight of Testudinis Carapax et Plastrum Preparata Cum Aceto, 20-30 parts by weight of Trionycis Carapax Preparata Cum Aceto, 30 parts by weight ofAgrimoniae Herba, 10-20 parts by weight ofAlpiniae Oxyphyllae Fructus, 5 parts by weight of Toosendan Fructus, 20 parts by weight of Poria, 10 parts by weight of Platycodonis Radix, and 10 parts by weight of Polygalae Radix.

Abstract: Systems and methods for implementation of a disposable miniaturized implant for treatment of Post-Operative Ileums (POI), a miniaturized implant for treating chronic GI dysmotility (e.g., dysphagia, gastroesophageal reflux disease (GERD), nausea, functional dyspepsia, blockage of transit, and gastroparesis, inflammatory bowel disease) and obesity, by providing electrical stimulation to the part of bowel going through surgery to expedite the healing process while recording the smooth muscle activities simultaneously, or providing stimulation on a treatment location of the GI tract or the branch of the vagus nerve. Systems and methods are also provided for non-invasive, transcutaneous stimulation of anatomy within the abdomen of the patient.

Abstract: Disclosed are a glass ceramic composition, a preparation method and application thereof. The glass ceramic composition according to the present application includes: 58% to 72% of SiO2; 0% to 4% of Al2O3; 0% to 5% of Na2O; 3% to 8% of K2O; 8% to 17% of Li2O; 2.5% to 5% of P2O5, 0% to 2% of MgO, 0% to 2.5% of B2O3; 0% to 5% of ZnO; and 0% to 3% of ZrO2. It is possible to prepare such lithium metasilicate glass ceramic with a crystal phase of lithium metasilicate, a crystallinity of greater than 50%, a grain size of 30 nm to 60 nm and a hardness of 500 kgf/mm2 to 590 kgf/mm2. The composition does not require an introduction of a high proportion of zirconia content, and can be ground to a thickness of 0.2 mm without edge collapse.

Abstract: A formulation includes a plurality of polymers including a hydrophobic polymer backbone (for example, formed via radical polymerization), a first plurality of pendant groups attached to the hydrophobic polymer backbone and including at least one cationic group, and a second plurality of pendant groups attached to the hydrophobic polymer backbone and including at least one hydrophilic polymer, a first therapeutic compound, and a second therapeutic compound, wherein the second therapeutic compound is different from the first therapeutic compound and includes a nucleic acid.

Abstract: The invention features combination therapies using an IL-15-based superagonist complex and an antibody to effectively treat subjects with cancer and infectious diseases.

Abstract: Transcription factors (TFs) represent a major class of therapeutic targets for the treatment of human diseases including cancer. Although the biological function and even crystal structure of many TFs have been clearly elucidated, there is still no viable approach to target the majority of TFs, thus rendering them undruggable for decades. PROTACs (PROteolysis TArgeting Chimeras) have emerged as a powerful tool for the pharmaceutical development since the effect of PROTACs largely relies on engineered protein-protein interaction to aid the degradation of targets by the ubiquitin-proteasome system (UPS). The present disclosure provides a DNA-PROTAC platform for targeted degraders of individual TFs of interest. These DNA based Transcription Factor targetting PROTACS (or “TF-PROTACS”) may provide specificity to TF degradation based on the conserved DNA-binding motifs of respective TFs.

Abstract: A system and method to match an interface to the face of a user for respiratory therapy. A facial image of the user is stored. Facial features based on the facial image are determined. A database stores facial profiles based on facial features and a corresponding plurality of interfaces. A database stores operational data of respiratory therapy devices with the plurality of corresponding interfaces. A selection engine is coupled to the databases. The selection engine is operative to select an interface for the user from the plurality of corresponding interfaces based on a desired outcome based on the stored operational data and the facial features. The collected data may also be employed to determine whether the selected interface is correctly fitted to the face of the user.

Abstract: A fitness device includes two support frames mounted in a box, two driving motors mounted on the two support frames, a pull rope reel connected to the driving motors, a fitness pull rope wound around the pull rope reel and extending out of the box, and a control system for controlling the driving motors. The control system includes a main controller, a power module, a communication module connected to the main controller, a driving circuit and a sampling module electrically connected to the driving motors and the main controller. The power module is electrically connected to the main controller and the communication module. The driving circuit is electrically connected to the power module, the main controller and the driving motors. The two symmetrical driving motors are used to drive the pull rope reel to drive the fitness pull rope, such that shakes and vibrations generated during exercise can be offset.

Abstract: A chamber adaptor and a manufacturing method thereof. The chamber adaptor includes: a housing provided with a gas inlet, a gas outlet, a chamber inlet, and a chamber outlet, where the gas inlet is configured to be removably connected to a main board device, the gas outlet is configured to be removably connected to a respiratory pathway, the chamber inlet is configured to be removably connected to an input end of a chamber for storing liquid and the chamber outlet is configured to be removably connected to an output end of the chamber, the chamber adaptor further includes a control circuit and at least one sensing apparatus, where the at least one sensing apparatus is arranged on one end of the control circuit closer to the gas outlet and extends into a gas output channel.

Abstract: A livestreaming method, apparatus and device, a storage medium, and a computer program product. The method includes: displaying a target object introduction page in response to triggering of the first permission control corresponding to a target object, during playing of a live video in a preview stage or after an end of the playing of the live video in the preview stage; displaying a permission operation interface in response to triggering of the second permission control; returning to a live video interface and playing the live video, in response to completing of an operation of at least one operation item of the permission operation interface. The target object introduction page includes the second permission control. A live video stream is blurred or stopped from being pushed after the end of the playing of the live video in the preview stage. The permission operation interface includes at least one operation item.

Abstract: A self-anchoring helical wire structure electrode for energy conduction to or from a tissue target in a body, made of at least one wire rope consisting of biocompatible and conductive wire, and enclosing a hollow core within an inner diameter and having a longitudinal axis, an outer diameter and two ends, being flexible for self-bending in any direction up to 180 degrees on said longitudinal axis, and secured by being capable of self-forming a bunching anchor wider than the insertion channel when injected while its dispenser is substantially stationary.

Abstract: Disclosed are a vehicle-mounted audio playing method and apparatus, a multimedia host, and a storage medium. The vehicle-mounted audio playing method includes: obtaining, by the multimedia host through a receiver, a first voice signal collected by a mobile microphone; and when the vehicle-mounted audio playing apparatus is in an out-of-vehicle karaoke mode, fusing, by the multimedia host, the first voice signal and an accompaniment signal, and outputting a fused signal to an out-of-vehicle speaker after performing amplification processing through a power amplifier, to drive the out-of-vehicle speaker to produce sound.

Abstract: Compositions and methods of using and manufacturing an oral pharmaceutical anhydrous suspension are provided. The anhydrous suspension is suitable to suspend active pharmaceutical ingredients (APIs), improve the stability of oral pharmaceutical suspensions, and help in the formation of a thermo-reversible gel and shear thinning to keep the APIs suspended. The anhydrous suspension disclosed herein may include glyceryl distearate NF (e.g., in an amount of from about 0.1 wt. % to about 10 wt. %) and stearoyl polyoxyl-32 glycerides NF (e.g., in an amount of from about 0.1 wt. % to about 10 wt. %). In embodiments, the anhydrous suspension also includes glycerin (e.g., in an amount of about 5 wt. %). The anhydrous suspension may also include one or more of medium chain triglycerides NF, vitamin E acetate (DL) USP liquid (1 IU/mg), flavoring agent (e.g., a sweeter or other flavoring agent), ascorbyl palmitate NF, and other components.

Abstract: A machine and its associated process for upset forging the ends of deformed reinforcement bars are disclosed. The machine includes 2 split clamping dies and an upsetting die, and they are housed in separate casings so that the clamping action is independent from the upsetting die. The clamping dies and the upsetting die form a continuous cavity for accommodating the forging of long bars. The upsetting die has a upsetting cavity with radial closed cross-section, and the whole forging process is performed inside this closed cavity to ensure it's a true closed-die forging process, which results in precise upset diameter with improved roundness of the rebar.