Abstract: The present disclosures relates to methods and apparatus for managing a blockchain. The method includes executing an initial transaction to obtain an initial transaction execution record; adding the initial transaction execution record to a first transaction execution data set; adding the initial transaction to a first transaction pool; acquiring transaction data from the first transaction pool that contains the initial transaction, the transaction data comprising respective initial transaction execution record corresponding to each transaction in a transaction list containing the initial transaction from the first transaction pool; generating a proposal block based on the transaction list and the transaction data, the proposal block being subject to block consensus with a second consensus node in the blockchain network; and performing block consensus on the proposal block to obtain a block consensus result of the proposal block.

Abstract: The present application discloses a semiconductor device with a composite barrier structure and a method for fabricating the semiconductor device. The semiconductor device includes a substrate; a first dielectric layer having a feature opening on a substrate; a composite barrier structure in the feature opening, wherein the composite barrier structure includes a barrier layer in the feature opening and an assisting blocking layer on the barrier layer; and a conductive feature on the assisting blocking layer; wherein the barrier layer comprises tantalum, and the assisting blocking layer comprises copper manganese alloy.

Abstract: The present disclosure discloses a double-edged art knife, including a knife shell and a knife holder; the knife shell is provided with an accommodating cavity and an opening; the opening is formed in a front end of the knife shell; the knife holder is separably mounted in the accommodating cavity of the knife shell; the opening is divided by the knife holder into a first opening and a second opening; the knife holder includes a knife rest and a pair of moving components; the moving components are symmetrically arranged on two sides of the knife rest; the moving components include a first moving component and the second moving component.

Abstract: Disclosed are systems and methods that provide a framework that allows for novel user interactions with dynamic messages using common reusable components and further allows for authentication of the user to the sender of the message. According to an embodiment, the framework functions by providing a message including a common reusable component with a corresponding content. The common reusable component allows the user to interact with the content. In some embodiments, in response to an interaction of the user with the common reusable component, a request is generated to the sender of the message to provide additional content or to perform an action. In some embodiments, the request includes an access token, a third-party token, or both. In some embodiments, the third-party token is created based on a credential of the user.

Abstract: Some embodiments provide a process of tunning sidewall profiles of gate openings prior to filling a replacement gate electrode layer therein to improve etching rate uniformity and stability during a subsequent gate electrode etch back process. Particularly, the profile sacrificial gate electrode is adjusted to be more straight profile rather than a bowl type profile, which reduces the seam void created in the replacement gate electrode during the replacement gate process. In some embodiments, tuning the profile of gate opening further includes performing a pullback etching process of the sidewall spacers prior to depositing gate dielectric layer and work function metal layer to achieve a wider opening for metal gate filling in the replacement gate process.

Abstract: An apparatus is disclosed for mixing signals. In example aspects, the apparatus includes a mixer circuit having multiple local oscillator nodes, a first node corresponding to a first frequency, and multiple second nodes corresponding to a second frequency. The mixer circuit includes multiple capacitors coupled between the multiple local oscillator nodes and the multiple second nodes. The mixer circuit has multiple switches including a first switch, a second switch, a third switch, and a fourth switch. The multiple switches are coupled between the multiple capacitors and the multiple second nodes. The first switch and the second switch are coupled between the multiple capacitors and the first node. The first switch and the second switch are disposed between the fourth switch and the third switch.

Abstract: An exemplary system, method, and computer-accessible medium for generating an image(s) of an three-dimensional anatomical flow map(s) can include receiving an optical coherence tomography (“OCT”) signal(s), splitting the OCT signal(s) into a plurality of subspectra, averaging the plurality of subspectra, and generating the image(s) of the three-dimensional anatomical flow map(s) based on the averaged subspectra. The OCT signal(s) can be a swept-source OCT signal. The OCT signal(s) can be split into the subspectra based on a Hamming window. The Hamming distance window can be optimized to minimize a nearest side lobe for each of the subspectra. A position of at least one of the subspectra can be shifted prior to averaging the subspectra. The position of all but one of the subspectra can be shifted prior to averaging the subspectra.

Abstract: A method includes providing a substrate having a gate structure over a first side of the substrate, forming a recess adjacent to the gate structure, and forming in the recess a first semiconductor layer having a dopant, the first semiconductor layer being non-conformal, the first semiconductor layer lining the recess and extending from a bottom of the recess to a top of the recess. The method further includes forming a second semiconductor layer having the dopant in the recess and over the first semiconductor layer, a second concentration of the dopant in the second semiconductor layer being higher than a first concentration of the dopant in the first semiconductor layer.

Abstract: The disclosure provides compositions and methods related to activating alpha-kinase 1 (ALPK1) for modulating an immune response and treating or preventing cancer, infection, inflammation and related diseases and disorders as well as potentiating an immune response to a target antigen. The disclosure also provides heterocyclic compounds of formula (I) as agonists of alpha protein kinase 1 (ALPK1) and their use in activating ALPK1, modulating an immune response and treating diseases such as cancer, wherein A1, A2, L1, L2, L3, Z1, Z2, W1, W2, R1, R2, R3, R4, R5, R6 and R7 are defined herein.

Abstract: A method and device are disclosed from the perspective of a first User Equipment (UE) to support Sidelink (SL) Discontinuous Reception (DRX). In one embodiment, the method includes the first UE establishing a unicast link with a second UE. The method further includes the first UE receiving a SL DRX configuration associated with the second UE from the second UE. The method also includes the first UE transmitting the SL DRX configuration to a network node. In addition, the method includes the first UE receiving a sidelink grant from the network node, wherein the sidelink grant indicates sidelink resources. Furthermore, the method includes the first UE performing a sidelink transmission to the second UE based on the sidelink resources.

Abstract: Technologies related to predicting whether a requested change (deployment) in a cloud computing environment will fail are described herein. An exposomic feature value is computed based upon a time series of risk values, where the risk values represent risk of failure over several historic time intervals. A probabilistic model computes a likelihood that the requested deployment will fail during implementation of the requested deployment based upon the exposomic feature value and a contextual feature value, and a notification is transmitted to a computing device of a change manager to allow the change manager to take remedial action.

Abstract: A electronic device is provided. The electronic device includes a circuit board, a first light-emitting element and a second light-emitting element disposed on the circuit board along a first direction. The backlight module includes a light guide plate and an adhesive structure between the circuit board and the light guide plate and having a first opening and a second opening. The first and second light-emitting elements are disposed in the first and second openings respectively. A portion of the adhesive structure disposed between the first and second openings includes a first part and a second part, the first part is disposed between the first and second light-emitting elements, and the second part is connected with the first part and extends toward the light guide plate. A second maximum width of the second part is greater than a first maximum width of the first part along the first direction.

Abstract: Techniques for chatbots, and more particularly, to techniques for using a directed acyclic graph (DAG) based framework to build and train models. In one particular aspect, a computer implemented method is provided that includes generating, by a DAG based framework, a first model and a second model, executing the first model for a chatbot in run-time and second model for the chatbot in design-time, collecting attributes for intent classification associated with a set of utterances with the chatbot running the first model and the second model, evaluating, using one or more metrics, performance of the first model and the second model based on an analysis of the attributes for the intent classification, determining whether the performance of the second model is improved as compared to the performance of the first model, and executing the first model or the second model for the chatbot in run-time based on the performance determination.

Abstract: Some embodiments relate to a method for forming an integrated chip. The method includes forming a bottom electrode over a substrate. A data storage layer is formed on the bottom electrode. A diffusion barrier layer is formed over the data storage layer. The diffusion barrier layer has a first diffusion activation temperature. A top electrode is formed over the diffusion barrier layer. The top electrode has a second diffusion activation temperature less than the first diffusion activation temperature.

Abstract: The present disclosure provides compositions and methods of eliciting an anti-tumor immune response and treating cancer comprising at least one peptide of KRAS.

Abstract: A stencil-avoidance design method, a stencil-avoidance design device, an electronic device, and a non-transitory storage medium are provided. The method includes: obtaining a plurality of first regions and a plurality of first stencil aperture regions; determining whether a shortest distance between a selected first region of the plurality of first regions and a selected first stencil aperture region of the plurality of first stencil aperture regions is within a preset threshold range; further obtaining a second region and a second stencil aperture region if the shortest distance is within the preset threshold range, and then obtaining a third region; performing a collision step if a collision test is required, and obtaining a final stencil aperture region. The above method can improve the efficiency, accuracy, coverage, and comprehensiveness of the stencil avoidance design.

Abstract: Disclosed in embodiments of the present disclosure are an anomaly detection method and apparatus. The method includes: detecting first feature data of collected first data using each anomaly detection algorithm, respectively, where N is an integer greater than or equal to 1; in response to first detection results corresponding to one or more anomaly detection algorithms being abnormal, performing reliability verification on the first feature data of the first data to obtain first verification results; and determining second detection results according to the first verification results and according to whether reliability of the one or more anomaly detection algorithms is greater than or equal to a first preset threshold.

Abstract: The present application relates to a method of producing drimenol and/or drimenol derivatives by comprising contacting at least one polypeptide with farnesyl diphosphate (FPP). The method may be performed in vitro or in vivo. Also provided are amino acid sequences of polypeptides useful in the methods and nucleic acids encoding the polypeptides described. The method further provides host cells or organisms genetically modified to express the polypeptides and useful to produce drimenol and/or derivatives of drimenol.