Abstract: A computer-implemented method that, when executed by data processing hardware, causes data processing hardware to perform operations comprising receiving a service request associated with a service request button of a vehicle, receiving one or more service button engagement scoring inputs each associated with a corresponding vehicle status, calculating a service request confidence score based on the one or more service button engagement scoring inputs, assigning a service request cancellation period based on the one or more service button engagement scoring inputs, determining whether a cancellation request is received within the service request cancellation period, and either cancelling the service request when the cancellation request is received within the service request cancellation period, or transmitting the service request to a service provider when the cancellation request is not received within the service request cancellation period.

Abstract: An accessory for temporarily holding a handheld electronic device. The accessory is a handheld electronic device holder configured to secure to a back of the handheld electronic device on one side. The other side of the handheld electronic device holder is removably attachable to a desired mounting surface allowing a user to operate the handheld electronic device in a handsfree configuration. The handheld electronic device holder is removably attachable to both the handheld electronic device and the desired mounting surface without damaging either.

Abstract: Systems and methods are provided for performing voice communication operations. The system establishes, by a first augmented reality (AR) device, a voice communication session between a plurality of users. The system displays, by the first AR device of a first user of the plurality of users, an avatar representing a second user of the plurality of users. The system receives, by the first AR device of a first user of the plurality of users, input from the first user that selects a display position for the avatar representing the second user within a real-world environment of the first user. The system animates the avatar representing the second user based on movement information received from a second AR device of the second user.

Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a network node may communicate with at least one user equipment (UE), wherein a blocking object is disposed between the network node and the at least one UE, the blocking object comprising at least one transmissive surface configured to refract incident beams. Numerous other aspects are described.

Abstract: A medical implant for managing blood flow through a blood vessel comprises a stent body forming a proximal portion and a tapered distal end, the tapered distal end being angled relative to the proximal portion to face a direction of blood flow and limit blood flow into an inner lumen of the stent body, and the tapered distal end having a flexible structure to allow the tapered distal end to bend and straighten in response to blood flow, and a covering extending along the stent body.

Abstract: A system and method are described herein for estimating power usage of various components of a CPU and controlling voltage regulators based on the estimated power usage. The power estimates may be based on digital power meter readings at each component, on voltage information from a voltage regulator, and on other power information. This power information is transmitted over a mesh interconnect disposed throughout the CPU such that power estimation can be accurately calculated and used to control voltage regulators without being limited by external bus speeds. More of the power management processes and components may be disposed on the CPU and connected to the mesh interconnect. These power management processes include various calibrations, adjustments, and limits so as efficiently manage and use the more rapidly processed power estimations.

Abstract: A device has an input port configured to receive as a device input a fundamental optical mode characterized by an input wavelength and a corresponding fundamental frequency; an output port configured to provide as a device output an Nth harmonic mode characterized by a Nth harmonic frequency relative to the fundamental frequency, where N>1; and a resonator with first and second coupler structures and first and second tuner elements. The first coupler structure is optimized for operation at the fundamental frequency, and the second coupler structure is optimized for operation at the Nth harmonic frequency. The first tuner element can change a refractive index experienced by each of the fundamental and Nth harmonic optical modes.

Abstract: Methods for the detection or quantitation of amyloid beta include detecting amyloid beta or fragments thereof by mass spectrometry. The methods may also include determining the ratio of amyloid beta 42 (A?42) to amyloid beta 40 (A?40). Such methods may include the diagnosis or prognosis of Alzheimer's disease or dementia.

Abstract: A method and a device for analysis of a profile of a real form of a surface of a part. The device determines and divides into subsections a deviation between the real form and the theoretical form. Then, for each subsection, a sinusoidal wave characterized by an amplitude b and a half-length of wave a is identified. When b is smaller than a predetermined value bmin or when a is smaller than a predetermined value amin, then the device stops the analysis, otherwise a new iteration of the analysis is carried out, considering the sinusoidal wave identified as a new profile of a theoretical form of the surface. Upon completion of the analysis phase, an alert message is generated if the values b and/or b/a do not comply with a manufacturing tolerance criterion.

Abstract: In one embodiment, a method includes receiving air into a device that includes an actuator for generating one or more toroidal vortices and determining whether to generate a toroidal vortex for conditioning air in an environment of the device or whether to generate a toroidal vortex for a non-temperature-related functionality. The method further includes generating, based on the determination and by the actuator, one or more toroidal vortices and transmitting, by the device, the one or more toroidal vortices into the environment.

Abstract: Substituted furanopyrimidine chemical entities of Formula (I): wherein Ra has any of the values described herein, and compositions comprising such chemical entities; methods of making them; and their use in a wide range of methods, including metabolic and reaction kinetic studies; detection and imaging techniques; radioactive therapies; modulating and treating disorders mediated by PDE1 activity or dopaminergic signaling; treating neurological disorders, CNS disorders, dementia, neurodegenerative diseases, and trauma-dependent losses of function; treating stroke, including cognitive and motor deficits during stroke rehabilitation; facilitating neuroprotection and neurorecovery; enhancing the efficiency of cognitive and motor training, including animal skill training protocols; and treating peripheral disorders, including cardiovascular, renal, hematological, gastroenterological, liver, cancer, fertility, and metabolic disorders.

Abstract: Methods for treating a cerebral aneurysm may include advancing a resilient self-expanding implant coupled to a pusher within a microcatheter to the cerebral aneurysm within the patient's vasculature. The implant may include a permeable shell, a coil extending from a distal end of the permeable shell, and a bioactive agent. The implant may be deployed within the cerebral aneurysm, where the coil and the permeable shell each assume an expanded deployed configuration. In an expanded deployed configuration, the coil has at least one loop having a secondary diameter and the permeable shell has an axially shortened configuration relative to a radially constrained elongated configuration.

Abstract: Devices, methods, and systems for placing dental auxiliaries on teeth are provided. In some embodiments, for example, a dental auxiliary positioner for placing a dental auxiliary on a tooth includes: a registration element configured to receive a patient's tooth; and an auxiliary support coupled to the registration element and further coupled to an auxiliary, where the auxiliary support is configured to position the auxiliary against a surface of the tooth, and where the auxiliary support includes a frame extending at least partially around the auxiliary, one or more struts coupling the auxiliary to the frame, and a flexible bridge coupling the frame to the registration element, where the flexible bridge is configured to bend in one or more directions relative to the tooth to adjust the position of the auxiliary on the surface of the tooth.

Abstract: The present disclosure provides isolated binding molecules that bind to and activates CD137, vectors comprising a nucleic acid molecules encoding an amino acid sequence of the binding molecules, host cells containing the vectors, methods of making the binding molecules, pharmaceutical compositions containing the binding molecules, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating a disease requiring stimulation of immune responses including cancer.

Abstract: The present disclosure includes engineering methods and polypeptide libraries that are useful for introducing non-native binding sites into polypeptides. Also provided herein are polypeptides that bind to a CD98hc or transferrin receptor (TfR) protein, methods of generating such polypeptides, and methods of using the polypeptides to target a composition across the blood-brain barrier or to a CD98hc-expressing or TfR-expressing cell.

Abstract: Systems and processes for operating an intelligent automated assistant are provided. Upon receiving a user input requesting that a digital assistant initiate a task, performance of the task is initiated, and a task response is provided. If the digital assistant determines that task is associated with a first user interface, such as a non-digital assistant-specific user interface, the task response is provided using the first user interface.

Abstract: Multiple analytes may be dysregulated singularly or concurrently in certain physiological conditions and may be advantageously assayed together using analyte sensors capable of detecting multiple analytes. Certain analyte sensors capable of the detection of multiple analytes may include first and second working electrodes, analyte-responsive active areas disposed on each of the working electrodes, and reference and counter electrodes. Analyte sensors that include multiple working electrodes but do not include reference and counter electrodes can also be used in conjunction with another sensor that contains reference and counter electrodes, such that these electrodes are shared.