Abstract: The present invention relates to compositions and uses of novel high penetration compositions or high penetration prodrugs (HPP), in particular HPPs for non-steroidal anti-inflammatory agents (NSAIAs), which are capable of crossing biological barriers with high penetration efficiency. The HPPs herein are capable of being converted to parent active drugs or drug metabolites after crossing the biological barrier and thus can render treatments for the conditions that the parent drugs or metabolites can. Additionally, due to the ability of penetrating biological barriers, the HPPs herein are capable of reaching areas that parent drugs may not be able to access or to render a sufficient concentration at the target areas and therefore render novel treatments. The HPPs herein can be administered to a subject through various administration routes.

Abstract: A method for retrieving an inventory item based on a handling robot, where the handling robot includes: a storage frame; and a material handling device installed on the storage frame, and including a telescopic arm and a manipulator installed to the telescopic arm; and the method for retrieving an inventory item includes: driving, by the telescopic arm, the manipulator to extend to a preset position of warehouse shelf along a preset horizontal reference line; loading, by the manipulator that is remained on the reference line, the inventory item located in the preset position; driving, by the telescopic arm, the manipulator loaded with the inventory item to move to the storage frame along the reference line; and unloading, by the manipulator that is remained on the reference line, the inventory item to the storage frame.

Abstract: A method for processing a video includes determining characteristics regarding a current video block; determining an operational state regarding unsymmetrical quad-tree (UQT) splitting based on the determination of the characteristics, wherein the operational state indicates that whether the UQT splitting is enabled or disabled and/or indicates how to split the current video block into four partitions using the UQT splitting; and performing a conversion between the current video block and a bitstream representation of the current video block based on the operational state of UQT splitting.

Abstract: An operation method is applied to a memory device. The memory device includes a plurality of memory tiles. The operation method includes following steps: utilizing a first wear leveling process to perform an intra-tile wear leveling on the plurality of memory tiles by a processor; and utilizing a second wear leveling process to perform an inter-tile wear leveling on the plurality of memory tiles by the processor.

Abstract: A fingerprint identification sensor may include a substrate (100), at least a photosensitive element (200) above the substrate (100), and at least a light source assembly (300). The light source assembly (300) may include a point light source (310) and a diffusing structure (320). The diffusing structure (320) may be configured to reduce intensity of light received by the photosensitive element (200) from a center region of the point light source (310).

Abstract: Methods and apparatus for constructing polar codes are provided. A transmitter determines at least one set of parameters corresponding to data to be transmitted, and a set of sorting indices corresponding to bits of the data to be transmitted based on the set of parameters, the set of sorting indices indicating a position set of the bits to be transmitted. The transmitter polar encodes the data based at least on the set of parameters and the set of sorting indices to generate a coded block of the data, and transmits the coded block of the data.

Abstract: Methods, systems, and devices for wireless communications are described. A communication device, otherwise known as a user equipment (UE) may receive a downlink control information (DCI) message including an indication to enable discontinuous monitoring of a physical downlink control channel (PDCCH). The UE may enable the discontinuous monitoring of the PDCCH based on the received DCI message, and disable monitoring of the PDCCH during a temporal period in which at least one of physical downlink shared channel (PDSCH) reception, downlink reference signal monitoring, uplink reference signal transmissions, and channel reporting is enabled. The UE may thereby experience power saving by disabling monitoring of the PDCCH while still performing other wireless operations during the temporal period. The UE may, as a result, also include features for improvements to wireless communications and, in some examples, may promote high reliability and low latency wireless communications, among other benefits.

Abstract: The present disclosure provides compounds represented by Formula I: and the pharmaceutically acceptable salts and solvates thereof, wherein R1a, R1b, R1c, E, G, and Q are as defined as set forth in the specification. The present disclosure also provides compounds of Formula I for use to treat cancer or any other disease, condition, or disorder that is responsive to inhibition of menin.

Abstract: An immobilized chalcogen system or body includes an element of chalcogen, an electrically conductive material, and a hydrophilic membrane gate. The hydrophilic membrane gate may be used to isolate hydrophobic regions, one related to polychalcogenide ion(s) and another related to a hydrophobic electrolyte system. The hydrophilic membrane gate may prevent polychalcogenide from forming, and may provide control of undesirable parasitic mass transport and undesirable electron transport inside a chalcogen-based battery, and thereby allow the battery to cycle at a high specific capacity with a long cycling life. If desired, the immobilized chalcogen system or body may be employed in a cathode of a rechargeable battery.

Abstract: A method for processing a video includes determining a valid splitting type for a current video block; determining whether or how to signal a splitting type to be used for the current video block based on the determination of the valid splitting type; and performing a conversion between the current video block and a bitstream representation of the current video block in accordance with the determining results.

Abstract: This application provides a radio resource control (RRC) message sending method and an apparatus. According to the method, a distributed unit (DU) determines not to start an RLC polling mechanism when sending an RRC message to a terminal device, so that when sending the RRC message to UE, the DU sets a polling bit in a header of an RLC PDU carrying the RRC message to be in an inactive state. Therefore, after receiving the RRC message, the terminal device does not feed back an RLC status report to the DU. Therefore, the terminal device does not need to initiate a random access procedure to obtain an uplink transmission resource for sending the RLC status report to the DU, thereby saving random access resources.

Abstract: Midstream urine collection with a device having an upper portion which forms an initial collection well, and a lower portion divided into an initial stream collection reservoir and a midstream collection reservoir. The device further includes a collection cavity and drain to allow a urine stream to flow into the housing. The device further includes a rotatable diverter adapted to rotate between: a first position in which an actuation panel is positioned to separate the initial collection well from the initial stream collection reservoir and a deflection panel is positioned to separate the initial collection well from the midstream collection reservoir; and a second position in which the deflector panel deflects the urine stream received through the collection drain into the midstream collection reservoir. The actuation panel comprises a piece of absorbent material affixed to a top surface thereof, within the initial collection well.

Abstract: A fracturing fluid may comprise an aqueous based fluid and halloysite nanotubes, wherein the halloysite nanotubes comprise a cargo.

Abstract: Systems and methods are presented for providing a response to a user query. Reception of a user query is detected. An augmentation machine learning model is utilized to determine one or more variations of the user query that correspond to a semantic meaning of the user query. A plurality of response candidates is determined that correspond to the user query by comparing the user query and the one or more variations of the user query to a plurality of documents. A final response candidate is determined from the plurality of response candidates based on utilizing a semantic machine learning model to perform a semantic comparison between the plurality of response candidates and at least the user query.

Abstract: A method of treating tunnel collapse includes mounting a shield plate, a column, a support column to form a combined support and moving the combined support onto an operation platform, lifting up the combined support, and enabling the height of canopy to be greater than the height of an initial supporting arch. Actively contacting a surface of a collapse cavity by a fixed support column and bearing a load, and lifting a movable support column to the top of the collapse cavity and bearing a load. Mounting an initial supporting arch, and welding the initial supporting arch with the support column. Removing a hydraulic prop after the support column contacting the initial supporting arch is cut off and the load of the shield plate is transferred to a supporting shed. Mounting an exhaust pipe and a filling material pumping pipe, and pumping a filling material into a collapse cavity space.

Abstract: Disclosed are a resource configuration method, a terminal device, a network device, a chip, a computer readable storage medium, a computer program product, and a computer program. The method comprises: receiving first information, wherein the first information is used for obtaining a transmission resource or the first information comprises pre-configured/semi-statically configured transmission resources indicated by a network side; determining a transmission resource of a first type of service on the basis of the first information.

Abstract: The disclosure herein describes enhancing data durability of a base component using a delta component. A delta component is generated based on the base component becoming unavailable. The delta component is configured to include unwritten storage space with an address space matching the base component and a tracking bitmap associated with data blocks of the address space of the delta component. Write operations targeted for the base component are routed to the delta component. Based on the routed write operations, bits associated with data blocks affected by the write operations are changed in the tracking bitmap. Based on the base component becoming available, data blocks affected by routed write operations are identified based on the tracking bitmap and the identified data blocks are synchronized from the delta component to the base component. The delta component is then removed.

Abstract: An apparatus for micromachining a semiconductor material from opposing sides through synchronous coordination of laser and electrochemistry includes an optical path system, a stable low-pressure jet generation system, and an electrolytic machining system. The optical path system includes a laser generator, a beam expander, a reflector, a galvanometer, and a lens. The electrolytic machining system includes a direct-current pulsed power supply, an adjustable cathode fixture, an electrolyte tank, a current probe, and an oscilloscope. The stable low-pressure jet generation system provides an electrolyte flow into a metal needle. The electrolyte flow forms an electrolyte layer between a semiconductor material and a cathode copper plate, such that the cathode and the anode are in electrical contact with each other. In a method employing the apparatus, a laser beam is irradiated onto the semiconductor material to form a local high-temperature region, which leads to a localized increase in electrical conductivity.

Abstract: An eyepiece waveguide includes a set of waveguide layers having a world side and a user side. The eyepiece waveguide also includes a first cover plate having a first optical power and disposed adjacent the world side of the set of waveguide layers and a second cover plate having a second optical power and disposed adjacent the user side of the set of waveguide layers.

Abstract: A semiconductor device includes a substrate, a gate stack over the substrate and a gate spacer on a sidewall of the gate stack. The gate spacer includes an outer spacer and an inner spacer between the gate stack and the outer spacer. The outer spacer and the inner spacer have same k-value reduction impurities, and a concentration of the k-value reduction impurities in the inner spacer is greater than a concentration of the k-value reduction impurities in the outer spacer.