Abstract: A compound having a BCL-XL protein degradation function as shown in Formula I and a use thereof in preparation of a drug for diseases associated with BCL-XL activity.

Abstract: A transcription regulation system based on CRISPRi and CRISPRa, and an establishment method therefor and the use thereof. The system is a new transcription regulation system which has high expression intensity, a low leakage level and is flexible and programmable. Provided is a method for achieving high-intensity and low-leakage expression of a gene by means of the transcription regulation system, wherein a high-intensity transcription level is achieved while suppressing background expression by means of synergistic regulation on downstream signaling effect devices by means of CRISPRi and CRISPRa dev ices. The new transcription regulation system can obtain, by means of loading different input promoters, a new expression system for responding to a specific signal, and has application value in the development and establishment of an efficient heterologous protein expression platform and a microbial cell factory.

Abstract: There are provided methods, devices, and computer program products for image generation, particularly to debiasing text-to-image diffusion models. In a method, a plurality of images are obtained by an image generating model based on a prompt. The plurality of images comprises a plurality of instances of an object, respectively and the object is specified by the prompt. A plurality of attributes of the plurality of instances of the object are determined respectively. The image generating model is updated based on the plurality of attributes and a predetermined distribution of a plurality of predetermined attributes related to the object. With the above method, the images generated by the updated image generating model may follow the predetermined distribution, and the updated image generating model may output debiased results.

Abstract: A motor drive apparatus includes a three-phase inverter and a three-phase motor. A first terminal of the three-phase inverter is connected to a positive electrode of a power battery. A second terminal of the three-phase inverter is connected to a negative electrode of the power battery Three phase coils of the three-phase motor are respectively connected to midpoints of three phase legs of the three-phase inverter. The motor drive apparatus is configured to simultaneously control (i) a process of charging the power battery by a power supply module, (ii) a torque of the three-phase motor at a zero output, and (iii) the three-phase inverter and the three-phase motor to heat a heat exchange medium flowing through at least one of the three-phase inverter or the three-phase motor.

Abstract: Embodiments of the present disclosure provide a solution for video processing. A method for video processing is proposed. The method comprises: determining, for a conversion between a current video block of a video and a bitstream of the video, whether a candidate frame associated with the current video block is a co-located frame based on a frame type of the candidate frame, the co-located frame being co-located with a frame comprising the current video block; and performing the conversion based on the determining.

Abstract: The present disclosure relates to silver paste, and a preparation method and a use thereof, which belong to the field of device packaging technology. The silver paste of the present disclosure is prepared by a silver-ammonia complex and an aldehyde-containing organic solvent, wherein a molar ratio of the silver-ammonia complex to the aldehyde-containing organic solvent is in a range of from 1:1 to 1:5; the silver-ammonia complex is prepared by a silver ?-ketocarboxylate and an amino-containing organic solvent; and a molar ratio of the silver ?-ketocarboxylate to the amino-containing organic solvent is in a range of from 1:1 to 1:5. The silver paste of the present disclosure can achieve large-area (?30×30 cm2) packaging and interconnection of a wide-bandgap semiconductor device within 300° C. under a low pressure (?1 MPa) or without pressures.

Abstract: A robotic catheter system and methods for implementing corrective actions during use thereof. A method comprises: providing a catheter that has one or more bendable segments and a catheter tip, inserting the catheter into a bodily lumen and navigating the catheter through the lumen along an insertion trajectory while an actuation unit applies an actuation force to the one or more bendable segments; recording a navigation parameter in relation to the insertion trajectory while the catheter is moved through the lumen, displaying, on a display, a graphical representation of the navigation parameter relative to a threshold value indicative of a location along the insertion trajectory where a navigation error of the catheter can occur or has occurred; and outputting to the display an interactive user-guide showing one or more than one corrective actions that can be taken to correct and/or prevent the navigation error.

Abstract: This disclosure relates to performing data communication while in an inactive state in a cellular communication system.

Abstract: Provided is a dual-mode compressor. The dual-mode compressor includes a first scroll plate (31), a second scroll plate (32), and an impeller (33). The first scroll plate (31) and the second scroll plate (32) define a scroll compression working cavity (3a), and the impeller (33) defines a centrifugal compression flow channel (33d). The impeller (33) and the second scroll plate (32) are fixed relative to each other and are arranged coaxially, and the inlet of the centrifugal compression flow channels (33d) is communicated with the outlet of the scroll compression working cavity (3a).

Abstract: A processor-implemented method includes receiving sensor measurement data from a glucose sensor; selecting, based on the sensor measurement data, a first regional sensor glucose (SG) model from a first plurality of regional SG models for respective regions of a first plurality of regions of an input parameter space associated with the sensor measurement data, and a second regional SG model from a second plurality of regional SG models for respective regions of a second plurality of regions of the input parameter space; estimating a first SG value and a second SG value using the first regional SG model and the second regional SG model, respectively; and determining a predicted SG value based on a combination of the first SG value and the second SG value. The input parameter space is partitioned into the first plurality of regions and the second plurality of regions using different partition schemes.

Abstract: A detection method for detecting fault of insulator discharge based on image recognition includes the following steps: building an ultraviolet image dataset for an electrical equipment, building a neural network model for insulator discharge detection based on YOLOV5-T, the neural network model includes a CBS module, a CST module, a Concat module, a 1D-attention module, an Upsample module and a Detect module, training the neural network model by utilizing the ultraviolet image dataset for the electrical equipment, to obtain a trained neural network model, and inputting images to be recognized into the trained neural network model, to obtain fault detection results. A detection device is configured to implement the detection method.

Abstract: A gas turbine engine includes a gearbox assembly that includes a gearbox and a gutter for collecting a gearbox lubricant scavenge flow from the gearbox. The gutter is characterized by a lubricant extraction volume ratio between 0.01 and 0.3. The lubricant extraction volume ratio defined by: V G V GB . V G is a gutter volume of the gutter and VGB is a gearbox volume. The gas turbine engine includes a lubrication system that includes a lubricant tank that stores lubricant, one or more primary gearbox lubricant supply lines, one or more secondary gearbox lubricant supply lines, and a lubricant pump for supplying the lubricant to the gearbox assembly through the primary gearbox lubricant supply lines and the secondary gearbox lubricant supply lines. The lubrication system modulates a mass flow rate of the lubricant to the gearbox assembly through the primary gearbox lubricant supply lines or the secondary gearbox lubricant supply lines.

Abstract: A method and device used for discontinuous reception(DRX) for wireless communications. A first node receives first information, the first information indicates a first identity (ID); determines a start time of a first timer according to the first ID; at the start time of the first timer, starts the first timer; when the first timer is running, monitors a first radio signal in each candidate slot; herein, the first ID belongs to a link-layer ID; the start time of the first timer is a start time of a first time interval. The start time of a first timer is determined according to a first ID, which can randomize start times of a user's DRX, avoiding possible system congestion and increasing transmission accuracy.

Abstract: A method can include modeling a state of each battery cell within a battery pack and contemporaneously with discharging a first subset of battery cells of the battery pack either providing a differential drain on the first subset of battery cells such that battery cells of the first subset of battery cells are discharged faster than a second subset of battery cells or charging the second subset of battery cells (e.g., using the first subset of battery cells) where battery cells are identified as in the first subset or the second subset based on the states of the battery cells.

Abstract: Disclosed is a method for inducing Iris domestica seed buds to generate polyploid, including the following steps: seed bud induction: inducing Iris domestica seeds at a low temperature, then soaking, sterilizing and germinating the same to obtain Iris domestica seed buds; and polyploid induction: soaking the obtained Iris domestica seed buds in oryzalin solution for polyploid induction to obtain mutagenized buds. In the present disclosure, the Iris domestica seed buds are treated by soaking with oryzalin to induce polyploid, and a total of 737 new germplasms of polyploid Iris domestica are obtained. The breeding has a short experimental period, simple operations, and high polyploid induction efficiency. At the same time, polyploids with large flowers, bright colors and strong plants are obtained. The method lays the foundations for the polyploid breeding of Iris domestica and the cultivation of new varieties of Iris domestica with large flower type and strong resistance.

Abstract: A battery system includes multiple battery cells each having a cell vent configured to vent flames originating from the battery cell in the event of a thermal runaway condition of the battery cell, and an insulator disposed adjacent a first battery cell, wherein the insulator comprises a hinged element configured to align with the cell vent of the first battery cell. In a closed position, the hinged element provides insulation for the first battery cell, and in an open position, the hinged element provides a vent to enable flames venting from the cell vent of the first battery cell to escape from between the insulator and the first battery cell to thereby inhibit the flames venting from the cell vent of the first battery cell from reaching a second battery cell.

Abstract: Implementations of three-dimensional (3D) memory devices and fabricating methods thereof are disclosed. In some implementations, the disclosed 3D memory device comprises: a stack structure including a plurality of dielectric layers and conductive layers alternatively stacked in a vertical direction; an array of channel structures each vertically penetrating the stack structure, each channel structure including a functional layer and a channel layer; and a plurality of isolation structures extending in parallel along a first lateral direction and vertically in an upper portion of the stack structure, each isolation structure being in contact with the channel layers of two adjacent rows of channel structures.

Abstract: Disclosed are a method and a system for mental state perception and a computer-readable storage medium. The method includes: acquiring image sequences with timestamps and millimeter-wave radar raw data with timestamps; preprocessing the image sequences and the millimeter-wave radar raw data; analyzing the head region image sequences to obtain head vibration signal features; calculating face region image sequences obtained from preprocessing by using a remote photovolumetric pulse wave recording method to obtain a first heart rate; analyzing the original millimeter-wave radar data sequence to obtain a second heart rate and a breathing rate; fusing the first heart rate, the second heart rate and the breathing rate to obtain a fused heart rate and breathing rate; performing feature extraction on facial change information by a Transformer-like network; establishing a non-contact multi-modal mental perception model for prediction to obtain a predicted result of the mental state.

Abstract: A thin film transistor includes a substrate; and a semiconductor layer a gate, a source electrode and a drain electrode; which are arranged on the substrate. The semiconductor layer includes a first material layer and a second material layer which are stacked, wherein a material of the first material layer is selected from one of or a combination of first n-type metal oxide semiconductor materials, and a material of the second material layer is selected from one of or a combination of second n-type metal oxide semiconductor materials. A carrier mobility of a first n-type metal oxide semiconductor material is greater than or equal to 40 cm2/Vs, and a second n-type metal oxide semiconductor material is doped with Y, Y being selected from one of or a combination of rare earth elements. The first material layer is closer to the gate than the second material layer.

Abstract: An ultraviolet LED device and a manufacturing method therefor is provided according to an embodiment of the disclosure. The ultraviolet LED device includes: a substrate (1), an AlN buffer layer (2), an n-AlGaN layer (3), a quantum well region (4), an electron blocking layer (5), a p-type GaN layer (6), and an etched trench region (7). The AlN buffer layer (2) is disposed on the substrate (1). The n-AlGaN layer (3) is disposed on the AlN buffer layer (2). The quantum well region (4) is disposed on the n-AlGaN layer (3). The electron blocking layer (5) is disposed on the quantum well region (4). The p-type GaN layer (6) is disposed on the electron blocking layer (5). The etched trench region (7) is etched downwards from the p-type GaN layer (6). The etched trench region (7) is obtained by etching from the p-type GaN layer (6) along a direction pointing toward the substrate (1). An etching angle of the etched trench region (7) is greater than 0 degree and less than or equal to 90 degrees.