Patents by Inventor Anan Chuntharapai

Anan Chuntharapai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apo-2 receptor agonist antibodies
    Patent number: 7807153
    Abstract: Novel polypeptides, designated Apo-2, which are capable of modulating apoptosis are provided. Compositions including Apo-2 chimeras, nucleic acid encoding Apo-2, and antibodies to Apo-2 are also provided.
    Type: Grant
    Filed: April 25, 2003
    Date of Patent: October 5, 2010
    Assignee: Genentech, Inc.
    Inventors: Camellia W. Adams, Avi J. Ashkenazi, Anan Chuntharapai, Kyung Jin Kim
  • Antibody compositions for the diagnosis and treatment of tumor
    Patent number: 7803915
    Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Grant
    Filed: September 8, 2004
    Date of Patent: September 28, 2010
    Assignee: Genentech, Inc.
    Inventors: Belinda Cairns, Ruihuan Chen, Gretchen Frantz, Kenneth J. Hillan, Hartmut Koeppen, Heidi S. Phillips, Paul Polakis, Susan D. Spencer, Victoria Smith, P. Mickey Williams, Thomas D. Wu, Zemin Zhang, Chie Sakanaka, Anan Chuntharapai, Chae Janeka Reed
  • Human DR4 antibodies and uses thereof
    Patent number: 7744881
    Abstract: Human Death Receptor 4 (DR4) antibodies are provided. The human DR4 antibodies may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treatment and diagnosis using the DR4 antibodies are also provided.
    Type: Grant
    Filed: June 28, 2007
    Date of Patent: June 29, 2010
    Assignee: Genentech, Inc.
    Inventors: Anan Chuntharapai, Kyung Jin Kim
  • Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling
    Patent number: 7737259
    Abstract: Compositions and methods are provided for the diagnosis and treatment of inflammation and autoimmune disorders, such as psoriasis. Compositions and methods for modulating IL-23 or IL-22 signaling are provided.
    Type: Grant
    Filed: November 30, 2006
    Date of Patent: June 15, 2010
    Assignee: Genentech, Inc.
    Inventors: Yvonne M. Chen, Anan Chuntharapai, Dimitry Danilenko, Wenjun Ouyang, Susan Sa, Patricia Valdez, Terence Wong, Jianfeng Wu, Yan Zheng
  • Method for making monoclonal antibodies and cross-reactive antibodies obtainable by the method
    Publication number: 20100136624
    Abstract: A method of making monoclonal antibodies according to a mixed antigen immunization protocol is described. In addition, antibodies obtainable by the method are disclosed which specifically cross-react with two or more different receptors to which Apo-2 ligand (Apo-2L) can bind.
    Type: Application
    Filed: July 30, 2009
    Publication date: June 3, 2010
    Applicant: Genentech, Inc.
    Inventors: Avi J. Ashkenazi, Anan Chuntharapai, K. Jin Kim
  • Treatment of cancer using anti-Apo-2 antibodies
    Patent number: 7595046
    Abstract: Novel polypeptides, designated Apo-2, which are capable of modulating apoptosis are provided. Compositions including Apo-2 chimeras, nucleic acid encoding Apo-2, and antibodies to Apo-2 are also provided.
    Type: Grant
    Filed: December 9, 2005
    Date of Patent: September 29, 2009
    Assignee: Genentech, Inc.
    Inventors: Camellia W. Adams, Avi J. Ashkenazi, Anan Chuntharapai, Kyung Jin Kim
  • Method for making monoclonal antibodies and cross-reactive antibodies obtainable by the method
    Patent number: 7592439
    Abstract: A method of making monoclonal antibodies according to a mixed antigen immunization protocol is described. In addition, antibodies obtainable by the method are disclosed which specifically cross-react with two or more different receptors to which Apo-2 ligand (Apo-2L) can bind.
    Type: Grant
    Filed: April 24, 2007
    Date of Patent: September 22, 2009
    Assignee: Genentech, Inc.
    Inventors: Avi J. Ashkenazi, Anan Chuntharapai, K. Jin Kim
  • COMBINATORIAL THERAPY
    Publication number: 20090220504
    Abstract: The present invention relates to the use of VEGF antagonists and alpha5beta1 antagonists for treating cancer and inhibiting angiogenesis and/or vascular permeability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to use of a VEGFR agonists and alpha5beta1 agonists to promote angiogenesis and vascular permeability. The present invention also relates to new anti-alpha5beta1 antibodies, compositions and kits comprising them and methods of making and using them.
    Type: Application
    Filed: March 21, 2007
    Publication date: September 3, 2009
    Inventors: Anan Chuntharapai, Gregory D. Plowman, Marc Tessier-Lavigne, Yan Wu, Weilan Ye
  • Apoptotic Anti-IgE Antibodies
    Publication number: 20090010924
    Abstract: The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.
    Type: Application
    Filed: March 21, 2008
    Publication date: January 8, 2009
    Applicant: GENENTECH, INC.
    Inventors: Lawren Wu, Mercedesz Balazs, Hans Brightbill, Andrew Chan, Yvonne Chen, Anan Chuntharapai, Mark Dennis, Terence Wong
  • Human DR4 antibodies and uses thereof
    Publication number: 20080233646
    Abstract: Human Death Receptor 4 (DR4) antibodies are provided. The human DR4 antibodies may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treatment and diagnosis using the DR4 antibodies are also provided.
    Type: Application
    Filed: June 28, 2007
    Publication date: September 25, 2008
    Inventors: Anan Chuntharapai, Kyung Jin Kim
  • Assay for Antibodies
    Publication number: 20080176257
    Abstract: The presence and quantity of an antibody of interest in a patient's bloodstream or other biological sample can serve as an important clinical or other analytical or diagnostic tool. ELISA methods, and kits for such assays, as well as anti-idiotypic antibodies and hybridomas producing them, are developed to detect levels of the antibody in biological samples, which are from, for example, animal models and human patients.
    Type: Application
    Filed: September 26, 2006
    Publication date: July 24, 2008
    Applicant: Genentech, Inc.
    Inventors: Anan Chuntharapai, Kyu Hong, Yu-Ju Meng
  • Method for making monoclonal antibodies and cross-reactive antibodies obtainanble by the method
    Publication number: 20080176286
    Abstract: A method of making monoclonal antibodies according to a mixed antigen immunization protocol is described. In addition, antibodies obtainable by the method are disclosed which specifically cross-react with two or more different receptors to which Apo-2 ligand (Apo-2L) can bind.
    Type: Application
    Filed: April 24, 2007
    Publication date: July 24, 2008
    Applicant: Genentech, Inc.
    Inventors: Avi J. Ashkenazi, Anan Chuntharapai, K. Jin Kim
  • TACI ANTIBODIES AND USES THEREOF
    Publication number: 20080171036
    Abstract: TACI receptor antibodies are provided. The TACI antibodies may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treatment and diagnosis using the TACI antibodies are also provided.
    Type: Application
    Filed: August 20, 2007
    Publication date: July 17, 2008
    Inventors: Anan Chuntharapai, Iqbal Grewal, Kyung Jin Kim, Minhong Yan
  • MONOCLONAL ANTIBODIES TO TYPE I INTERFERON RECEPTOR
    Publication number: 20080102072
    Abstract: Anti-IFNAR1 monoclonal antibodies with neutralizing activities against the anti-viral cytopathic effects of various type I interferons are provided.
    Type: Application
    Filed: October 4, 2007
    Publication date: May 1, 2008
    Applicant: Genentech, Inc.
    Inventors: Anan CHUNTHARAPAI, Kyung Kim, Richard Love, Ji Lu
  • DR4 antibodies and uses thereof
    Publication number: 20080095700
    Abstract: Death Receptor 4 (DR4) antibodies are provided. The DR4 antibodies may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treatment and diagnosis using the DR4 antibodies are also provided.
    Type: Application
    Filed: May 9, 2007
    Publication date: April 24, 2008
    Inventors: Avi Ashkenazi, Anan Chuntharapai, Kelly Dodge, Kyung Kim
  • DR4 antibodies and uses thereof
    Publication number: 20080095781
    Abstract: Death Receptor 4 (DR4) antibodies are provided. The DR4 antibodies may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treatment and diagnosis using the DR4 antibodies are also provided.
    Type: Application
    Filed: May 9, 2007
    Publication date: April 24, 2008
    Inventors: Avi Ashkenazi, Anan Chuntharapai, Kyung Kim
  • Inducing apoptosis using anti-Apo-2 antibodies
    Patent number: 7314619
    Abstract: Novel polypeptides, designated Apo-2, which are capable of modulating apoptosis are provided. Compositions including Apo-2 chimeras, nucleic acid encoding Apo-2, and antibodies to Apo-2 are also provided.
    Type: Grant
    Filed: November 2, 2001
    Date of Patent: January 1, 2008
    Assignee: Genentech, Inc.
    Inventors: Camellia W. Adams, Avi J. Ashkenazi, Anan Chuntharapai, Kyung Jin Kim
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASES AND DISORDERS ASSOCIATED WITH CYTOKINE SIGNALING
    Publication number: 20070212356
    Abstract: Compositions and methods are provided for the diagnosis and treatment of inflammation and autoimmune disorders, such as psoriasis. Compositions and methods for modulating IL-23 or IL-22 signaling are provided.
    Type: Application
    Filed: November 30, 2006
    Publication date: September 13, 2007
    Inventors: Yvonne Chen, Anan Chuntharapai, Dimitry Danilenko, Wenjun Ouyang, Susan Sa, Patricia Valdez, Terence Wong, Jianfeng Wu, Yan Zheng
  • Human DR4 antibodies and uses thereof
    Patent number: 7252994
    Abstract: Human Death Receptor 4 (DR4) antibodies are provided. The human DR4 antibodies may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treatment and diagnosis using the DR4 antibodies are also provided.
    Type: Grant
    Filed: June 29, 2002
    Date of Patent: August 7, 2007
    Assignee: Genentech, Inc.
    Inventors: Anan Chuntharapai, Kyung Jin Kim
  • Method of Producing Pan-Specific Antibodies
    Publication number: 20070161089
    Abstract: Pan-specific anti-humanized antibody antibody (anti-hzAbAb) are described as well as and methods for generating and using pan-specific anti-humanized antibody antibodies (anti-hzAbAb) that selectively bind related antibodies such as those therapeutic humanized having variable domain framework regions sharing at least 80% sequence identity and/or those having variable domain framework regions sharing at least 80% sequence identity with a variable domain consensus sequence.
    Type: Application
    Filed: November 6, 2006
    Publication date: July 12, 2007
    Applicant: GENENTECH, INC.
    Inventors: Jihong Yang, Anan Chuntharapai