Patents by Inventor Anan Chuntharapai

Anan Chuntharapai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for targeting IFNAR2
    Publication number: 20070081995
    Abstract: Anti-IFNAR2 monoclonal antibodies, and methods for using the antibodies, are provided.
    Type: Application
    Filed: June 21, 2006
    Publication date: April 12, 2007
    Inventors: Anan Chuntharapai, Kerstin Schmidt
  • Anti-interferon-alpha antibodies
    Publication number: 20070059309
    Abstract: The present invention relates generally to the generation and characterization of neutralizing anti-IFN-? monoclonal antibodies with broad reactivity against various IFN-? subtypes. The invention further relates to the use of such anti-IFN-? antibodies in the diagnosis and treatment of disorders associated with increased expression of IFN-?, in particular, autoimmune disorders such as insulin-dependent diabetes mellitus (IDDM) and systemic lupus erythematosus (SLE).
    Type: Application
    Filed: March 10, 2006
    Publication date: March 15, 2007
    Applicant: GENENTECH, INC.
    Inventors: Anan Chuntharapai, Jin Kim, Leonard Presta, Timothy Stewart
  • ANTI-INTERFERON-alpha ANTIBODIES
    Publication number: 20070048311
    Abstract: The present invention relates generally to the generation and characterization of neutralizing anti-IFN-? monoclonal antibodies with broad reactivity against various IFN-? subtypes. The invention further relates to the use of such anti-IFN-? antibodies in the diagnosis and treatment of disorders associated with increased expression of IFN-?, in particular, autoimmune disorders such as insulin-dependent diabetes mellitus (IDDM) and systemic lupus erythematosus (SLE).
    Type: Application
    Filed: June 12, 2006
    Publication date: March 1, 2007
    Applicant: GENENTECH, INC.
    Inventors: Anan Chuntharapai, Jin Kim, Leonard Presta, Timothy Stewart
  • Apo-2DcR
    Publication number: 20070037191
    Abstract: Novel polypeptides, designated Apo-2DcR, which are capable of binding Apo-2 ligand are provided. Compositions including Apo-2DcR chimeras, nucleic acid encoding Apo-2DcR, and antibodies to Apo-2DcR are also provided.
    Type: Application
    Filed: June 27, 2006
    Publication date: February 15, 2007
    Applicant: Genentech, Inc.
    Inventors: Avi Ashkenazi, Kevin Baker, Anan Chuntharapai, Austin Gurney, Kyung Kim, William Wood
  • Assay for Antibodies
    Publication number: 20070015228
    Abstract: The presence and quantity of an antibody of interest in a patient's bloodstream or other biological sample can serve as an important clinical or other analytical or diagnostic tool. ELISA methods, and kits for such assays, as well as anti-idiotypic antibodies and hybridomas producing them, are developed to detect levels of the antibody in biological samples, which are from, for example, animal models and human patients.
    Type: Application
    Filed: September 26, 2006
    Publication date: January 18, 2007
    Applicant: Genentech, Inc.
    Inventors: Anan Chuntharapai, Kyu Hong, Yu-Ju Meng
  • Method for making monoclonal antibodies and cross-reactive antibodies obtainable by the method
    Publication number: 20070015247
    Abstract: A method of making monoclonal antibodies according to a mixed antigen immunization protocol is described. In addition, antibodies obtainable by the method are disclosed which specifically cross-react with two or more different receptors to which Apo-2 ligand (Apo-2L) can bind.
    Type: Application
    Filed: June 15, 2006
    Publication date: January 18, 2007
    Inventors: Avi Ashkenazi, Anan Chuntharapai, K. Kim
  • Apo-2 receptor
    Publication number: 20060251647
    Abstract: Novel polypeptides, designated Apo-2, which are capable of modulating apoptosis are provided. Compositions including Apo-2 chimeras, nucleic acid encoding Apo-2, and antibodies to Apo-2 are also provided.
    Type: Application
    Filed: December 9, 2005
    Publication date: November 9, 2006
    Inventors: Camellia Adams, Avi Ashkenazi, Anan Chuntharapai, Kyung Kim
  • Apo-2 receptor antibodies
    Publication number: 20060177456
    Abstract: Novel polypeptides, designated Apo-2, which are capable of modulating apoptosis are provided. Compositions including Apo-2 chimeras, nucleic acid encoding Apo-2, and antibodies to Apo-2 are also provided.
    Type: Application
    Filed: April 13, 2006
    Publication date: August 10, 2006
    Inventors: Avi Ashkenazi, Anan Chuntharapai, K. Kim
  • Anti-interferon-? antibodies
    Patent number: 7087726
    Abstract: The present invention relates generally to the generation and characterization of neutralizing anti-IFN-? monoclonal antibodies with broad reactivity against various IFN-? subtypes. The invention further relates to the use of such anti-IFN-? antibodies in the diagnosis and treatment of disorders associated with increased expression of IFN-?, in particular, autoimmune disorders such as insulin-dependent diabetes mellitus (IDDM) and systemic lupus erythematosus (SLE).
    Type: Grant
    Filed: January 9, 2002
    Date of Patent: August 8, 2006
    Assignee: Genentech, Inc.
    Inventors: Anan Chuntharapai, Jin K. Kim, Leonard G. Presta, Timothy Stewart
  • Apo-2 receptor
    Publication number: 20060115484
    Abstract: Novel polypeptides, designated Apo-2, which are capable of modulating apoptosis are provided. Compositions including Apo-2 chimeras, nucleic acid encoding Apo-2, and antibodies to Apo-2 are also provided.
    Type: Application
    Filed: December 9, 2005
    Publication date: June 1, 2006
    Inventors: Camellia Adams, Avi Ashkenazi, Anan Chuntharapai, Kyung Kim
  • Assay for antibodies
    Publication number: 20060099662
    Abstract: The presence and quantity of an antibody of interest in a patient's bloodstream or other biological sample can serve as an important clinical or other analytical or diagnostic tool. ELISA methods, and kits for such assays, as well as anti-idiotypic antibodies and hybridomas producing them, are developed to detect levels of the antibody in biological samples, which are from, for example, animal models and human patients.
    Type: Application
    Filed: April 15, 2005
    Publication date: May 11, 2006
    Inventors: Anan Chuntharapai, Kyu Hong, Yu-Ju Meng
  • Apo-2 receptor
    Publication number: 20060084147
    Abstract: Novel polypeptides, designated Apo-2, which are capable of modulating apoptosis are provided. Compositions including Apo-2 chimeras, nucleic acid encoding Apo-2, and antibodies to Apo-2 are also provided.
    Type: Application
    Filed: December 9, 2005
    Publication date: April 20, 2006
    Inventors: Camellia Adams, Avi Ashkenazi, Anan Chuntharapai, Kyung Kim
  • Apo-2 receptor
    Publication number: 20060073570
    Abstract: Novel polypeptides, designated Apo-2, which are capable of modulating apoptosis are provided. Compositions including Apo-2 chimeras, nucleic acid encoding Apo-2, and antibodies to Apo-2 are also provided.
    Type: Application
    Filed: December 9, 2005
    Publication date: April 6, 2006
    Inventors: Camellia Adams, Avi Ashkenazi, Anan Chuntharapai, Kyung Kim
  • Apo-2 receptor
    Publication number: 20060035334
    Abstract: Novel polypeptides, designated Apo-2, which are capable of modulating apoptosis are provided. Compositions including Apo-2 chimeras, nucleic acid encoding Apo-2, and antibodies to Apo-2 are also provided.
    Type: Application
    Filed: October 7, 2005
    Publication date: February 16, 2006
    Inventors: Camellia Adams, Avi Ashkenazi, Anan Chuntharapai, Kyung Kim
  • Monoclonal antibodies to type I interferon receptor
    Publication number: 20060020118
    Abstract: Anti-IFNAR1 monoclonal antibodies with neutralizing activities against the anti-viral cytopathic effects of various type I interferons are provided.
    Type: Application
    Filed: March 29, 2004
    Publication date: January 26, 2006
    Applicant: Genentech, Inc.
    Inventors: Anan Chuntharapai, Kyung Kim, Richard Love, Ji Lu
  • Method for making monoclonal antibodies and cross-reactive antibodies obtainable by the method
    Publication number: 20050282230
    Abstract: A method of making monoclonal antibodies according to a mixed antigen immunization protocol is described. In addition, antibodies obtainable by the method are disclosed which specifically cross-react with two or more different receptors to which Apo-2 ligand (Apo-2L) can bind.
    Type: Application
    Filed: April 13, 2005
    Publication date: December 22, 2005
    Inventors: Avi Ashkenazi, Anan Chuntharapai, K. Kim
  • Compositions and methods for the diagnosis and treatment of tumor
    Publication number: 20050107595
    Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: September 10, 2004
    Publication date: May 19, 2005
    Inventors: Belinda Cairns, Ruihuan Chen, Gretchen Frantz, Kenneth Hillan, Hartmut Koeppen, Heidi Phillips, Paul Polakis, Susan Spencer, Victoria Smith, P. Williams, Thomas Wu, Zemin Zhang, Chie Sakanaka, Anan Chuntharapai, Chae Reed
  • TACI antibodies and uses thereof
    Publication number: 20050043516
    Abstract: TACI receptor antibodies are provided. The TACI antibodies may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treatment and diagnosis using the TACI antibodies are also provided.
    Type: Application
    Filed: July 25, 2003
    Publication date: February 24, 2005
    Applicant: Genentech, Inc.
    Inventors: Anan Chuntharapai, Iqbal Grewal, Kyung Kim, Minhong Yan
  • DR4 antibodies and uses thereof
    Publication number: 20040180049
    Abstract: Death Receptor 4 (DR4) antibodies are provided. The DR4 antibodies may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treatment and diagnosis using the DR4 antibodies are also provided.
    Type: Application
    Filed: July 30, 2003
    Publication date: September 16, 2004
    Applicant: Genentech, Inc.
    Inventors: Avi J. Ashkenazi, Anan Chuntharapai, Kyung Jin Kim
  • Human dr4 antibodies and uses thereof
    Publication number: 20040147725
    Abstract: Human Death Receptor 4 (DR4) antibodies are provided. The human DR4 antibodies may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treatment and diagnosis using the DR4 antibodies are also provided.
    Type: Application
    Filed: December 12, 2003
    Publication date: July 29, 2004
    Inventors: Anan Chuntharapai, Kyung Jin Kim