Abstract: A compression garment having one or more flex frames that can be shortened or lengthened to apply or release a compressive force to the limb or other anatomical feature of a user. The compression garment can have a wire made of shape memory material (shape memory alloy). A controller of the compression garment can supply an electrical input to the wire, generating heat that can cause the wire to contract such that the flex frame deflects to a shorter length to apply a compressive force to the limb or other anatomical feature of the user. The one or more flex frames can be contracted in unison or in sequence to direct the flow of bodily fluids in the limb or other anatomical feature of the user.

Abstract: Some embodiments of the invention advantageously leverage the expansion of the prostatic urethra using adjustable lumen tension rings (ALTRs) of desired sizes to control and improve flow throughout the range of the urethra. As such, some embodiments include tension ring(s) or cylinders that sits either inside or outside the prostatic wall and is at least partially within the lumen and/or is partially or fully anchored, attached, adhered, or otherwise held in place with respect to the bladder or other locations within the urethra and/or elsewhere in the urethra. The expansion of the lumen can be pre-configured based on pre-operative metrology of the prostatic urethra to a customized and adjustable fit across the various zones within the urethra and based on the patient specific and evolving needs.

Abstract: Described herein are polymer formulations for facilitating electrical stimulation of nasal or sinus tissue. The polymer formulations may be hydrogels that are prepared by a UV cross-linking process. The hydrogels may be included as a component of nasal stimulator devices that electrically stimulate the lacrimal gland to improve tear production and treat dry eye. Additionally, devices and methods for manufacturing the nasal stimulators, including shaping of the hydrogel, are described herein.

Abstract: Described herein are polymer formulations for facilitating electrical stimulation of nasal or sinus tissue. The polymer formulations may be hydrogels that are prepared by a UV cross-linking process. The hydrogels may be included as a component of nasal stimulator devices that electrically stimulate the lacrimal gland to improve tear production and treat dry eye. Additionally, devices and methods for manufacturing the nasal stimulators, including shaping of the hydrogel, are described herein.

Abstract: Systems and methods can advantageously leverage the pupillary accommodation reflex to provide improved quality of vision throughout the range of focus distances. As such, some embodiments include an accommodating pupillary lens (APL) that sits at least partially within the pupil and/or is partially or fully attached, adhered, or otherwise held in place with respect to the iris, and/or is anchored in the sulcus and/or elsewhere in the eye. The optical power of the lens can be configured to change with changes in pupil diameter.

Abstract: Described here are devices, systems, and methods for increasing tear production by stimulating the cornea, conjunctiva, and/or subconjunctiva. In some variations, the devices may be in the form of a contact lens. The contact lens may comprise a lens body and a stimulator chip, where the stimulator chip is embedded in the lens body. An external power source wirelessly transmits energy to the stimulator chip, where the stimulator chip may convert the energy to an electric waveform to stimulate the cornea, conjunctiva, and/or subconjunctiva. Stimulation may activate the lacrimal reflex to increase tear production. The devices and systems for increasing tear production may be used in methods of treating dry eye, reducing the symptoms of tired eye, increasing comfort for contact lens wearers, and extending the number of years a contact lens user can wear contacts. Also described are methods of manufacturing a contact lens.

Abstract: Described here are devices, systems, and methods for increasing tear production by stimulating the cornea, conjunctiva, and/or subconjunctiva. In some variations, the devices may be in the form of a contact lens. The contact lens may comprise a lens body and a stimulator chip, where the stimulator chip is embedded in the lens body. An external power source wirelessly transmits energy to the stimulator chip, where the stimulator chip may convert the energy to an electric waveform to stimulate the cornea, conjunctiva, and/or subconjunctiva. Stimulation may activate the lacrimal reflex to increase tear production. The devices and systems for increasing tear production may be used in methods of treating dry eye, reducing the symptoms of tired eye, increasing comfort for contact lens wearers, and extending the number of years a contact lens user can wear contacts. Also described are methods of manufacturing a contact lens.

Abstract: Described here are devices, systems, and methods for increasing tear production by stimulating the cornea, conjunctiva, and/or subconjunctiva. In some variations, the devices may be in the form of a contact lens. The contact lens may comprise a lens body and a stimulator chip, where the stimulator chip is embedded in the lens body. An external power source wirelessly transmits energy to the stimulator chip, where the stimulator chip may convert the energy to an electric waveform to stimulate the cornea, conjunctiva, and/or subconjunctiva. Stimulation may activate the lacrimal reflex to increase tear production. The devices and systems for increasing tear production may be used in methods of treating dry eye, reducing the symptoms of tired eye, increasing comfort for contact lens wearers, and extending the number of years a contact lens user can wear contacts. Also described are methods of manufacturing a contact lens.

Abstract: An intraocular lens comprises an optic and at least two haptics, each of which comprises a step feature that protrudes from a posterior surface of the haptic to prevent posterior capsular opacification.

Abstract: A composite ophthalmic device comprising an ophthalmic structure, means or lens having a photo-shifting material deployed thereon or therewithin so as to up-shift or down-shift the amplitude, wavelength (or both) of incident radiation into the visible wavelength range.

Abstract: An intraocular lens comprises an optic and at least two haptics. Each haptic is offset in an anterior direction from a central optic plane of the optic. The offset allows for predictable posterior vaulting upon implantation.