Patents by Inventor Anand Prakash

Anand Prakash has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel asymmetric synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid
    Publication number: 20090069600
    Abstract: The invention encompasses processes for the synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid, (S)-Pregabalin, and intermediates of (S)-Pregabalin.
    Type: Application
    Filed: October 28, 2008
    Publication date: March 12, 2009
    Inventors: Vinod Kumar Kansal, Brijnath P. Chaurasia, V. Govardhan Rao, Anand Prakash Tiwari
  • Novel asymmetric synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid
    Publication number: 20090069593
    Abstract: The invention encompasses processes for the synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid, (S)-Pregabalin, and intermediates of (S)-Pregabalin.
    Type: Application
    Filed: October 28, 2008
    Publication date: March 12, 2009
    Inventors: Vinod Kumar Kansal, Brijnath P. Chaurasia, V. Govardhan Rao, Anand Prakash Tiwari
  • Novel asymmetric synthesis of (S)-(+)-3-(Aminomethyl)-5-methylhexanoic acid
    Publication number: 20090062562
    Abstract: The invention encompasses processes for the synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid, (S)-Pregabalin, and intermediates of (S)-Pregabalin.
    Type: Application
    Filed: October 28, 2008
    Publication date: March 5, 2009
    Inventors: Vinod Kumar Kansal, Brijnath P. Chaurasia, V. Govardhan Rao, Anand Prakash Tiwari
  • Process for the purification of macrolides
    Patent number: 7473366
    Abstract: The invention relates to a process for the recovery of a macrolide in substantial pure form including: a) treating an impure or crude macrolide with water immiscible solvent to form a mixture, b) optionally concentrating the mixture, c) treating with ammonia gas to phase out impurities, d) separating impurities, e) optionally concentrating a phase containing the macrolide, f) loading on silica gel chromatography, optionally reversed phase or pretreated with silver, and eluting the macrolide, g) affording the macrolide in the substantially pure form, h) optional repetition of steps f and g to afford the macrolide in the substantially pure form. The macrolide is preferably tacrolimus, immunomycin or sirolimus.
    Type: Grant
    Filed: December 5, 2003
    Date of Patent: January 6, 2009
    Assignee: BioCon Limited
    Inventors: Nitin Sopanrao Patil, Rakesh Mendhe, Anand Prakash Khedkar, Ramakrishnan Melarkode, Ramavana Gururaja
  • Chiral 3-carbamoylmethyl-5-methyl hexanoic acids, key intermediates for the synthesis of (S)-Pregabalin
    Patent number: 7470812
    Abstract: The invention encompasses the synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid, (S)-Pregabalin, via the intermediate, (3R)-5-methyl-3-(2-oxo-2{[(1R)-1-phenylethyl]amino}ethyl)hexanoic acid.
    Type: Grant
    Filed: August 21, 2007
    Date of Patent: December 30, 2008
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Vinod Kumar Kansal, Brijnath P. Chaurasia, Anand Prakash Tiwari
  • Chiral 3-carbamoylmethyl-5-methyl hexanoic acids, key intermediates for the synthesis of (S)-pregabalin
    Patent number: 7465826
    Abstract: The invention encompasses the synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid, (S)-Pregabalin, via the intermediate, (3R)-5-methyl-3-(2-oxo-2{[(1R)-1-phenylethyl]amino}ethyl)hexanoic acid.
    Type: Grant
    Filed: August 21, 2007
    Date of Patent: December 16, 2008
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Vinod Kumar Kansal, Brijnath P. Chaurasia, Anand Prakash Tiwari
  • Synthesis of (S)-(+)-3-(aminomethyl)-5-methyl hexanoic acid
    Publication number: 20080306292
    Abstract: Provided are syntheses of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid, (S)-Pregabalin via a chiral intermediate of the following formula 4 wherein Ar is a C6-10 aromatic group, R is a straight or branched C1-4 alkyl, ester, or carboxylic acid, and R1 is a straight or branched C1-5 alkyl, aralkyl, or substituted aralkyl.
    Type: Application
    Filed: March 24, 2008
    Publication date: December 11, 2008
    Inventors: Vinod Kumar Kansal, Brijnath P. Chaurasia, Anand Prakash Tiwari, Shivaji Haribhau Shelke
  • Asymmetric synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid
    Patent number: 7446220
    Abstract: The invention encompasses processes for the synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid, (S)-Pregabalin, and intermediates of (S)-Pregabalin.
    Type: Grant
    Filed: September 19, 2006
    Date of Patent: November 4, 2008
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Vinod Kumar Kansal, Brijnath P. Chaurasia, V. Govardhan Rao, Anand Prakash Tiwari
  • Carbon Blacks Having Low PAH Amounts and Methods of Making Same
    Publication number: 20080159947
    Abstract: Carbon blacks, such as rubber blacks, having a low PAH concentration are described. Furthermore, elastomeric or rubber compositions containing the carbon black of the present invention are further described, as well as methods of making carbon black having a low PAH concentration.
    Type: Application
    Filed: November 6, 2007
    Publication date: July 3, 2008
    Inventors: Irina S. Yurovskaya, William L. Sifleet, Steven J. List, Martin C. Green, Anand Prakash
  • Manufacture and purification of cyclosporin A
    Patent number: 7176001
    Abstract: The present invention provides an improved method for the manufacture of Cyclosporin A is disclosed. Cyclosporin A is produced by solid state fermentation of Fusarium solani in a bioreactor under optimal fermentation parameters. The product is extracted and further purified by treating with alum and subsequent chromatographic procedures to get pharmaceutical acceptable purity.
    Type: Grant
    Filed: February 29, 2000
    Date of Patent: February 13, 2007
    Assignee: Biocon Limited
    Inventors: Anand Prakash Khedkar, Pampapathy Subramaniyam, Konayakanahalli Nanjunda Swamy Anand, Melarkode Ramkrishna, Shreehas Pradeep Tambe, Sambasivam Ganesh, Anindya Sircar, Shrikumar Suryanarayan
  • Manufacture and purification of mycophenolic acid
    Patent number: 6927047
    Abstract: The present invention provides an improved method for the manufacture of Mycophenolic acid by solid substrate fermentation of Pencillium brevi-campactum, in a contained bioreactor under optimal fermentation parameters with its subsequent purification steps.
    Type: Grant
    Filed: February 29, 2000
    Date of Patent: August 9, 2005
    Assignee: Biocon Limited
    Inventors: Anindya Sircar, Shrikumar Suryanarayan, Anand Prakash Khedkar, Pampapathy Subramaniyam, Shreehas Pradeep Tambe