Patents by Inventor Andrés Francesch

Andrés Francesch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240166666
    Abstract: A compound of general formula I and pharmaceutical compositions, kits, methods of making, and methods for treating cancer using the same.
    Type: Application
    Filed: June 22, 2023
    Publication date: May 23, 2024
    Inventors: Maria del Carmen Cuevas Marchante, Andres Francesch Solloso, Valentin Martinez Barrasa
  • Patent number: 11713325
    Abstract: A compound of general formula I and pharmaceutical compositions, kits, methods of making, and methods for treating cancer using the same.
    Type: Grant
    Filed: April 5, 2022
    Date of Patent: August 1, 2023
    Assignee: Pharma Mar, S.A.
    Inventors: Maria del Carmen Cuevas Marchante, Andres Francesch Solloso, Valentin Martinez Barrasa
  • Publication number: 20220242883
    Abstract: A compound of general formula I and pharmaceutical compositions, kits, methods of making, and methods for treating cancer using the same.
    Type: Application
    Filed: April 5, 2022
    Publication date: August 4, 2022
    Inventors: María del Carmen Cuevas Marchante, Andres Francesch Solloso, Valentin Martinez Barrasa
  • Publication number: 20220168436
    Abstract: Drug conjugates of formula [D-(X)b-(AA)w-(L)-]n-Ab wherein: D is a drug moiety having the following formula (I) or a pharmaceutically acceptable salt, ester, solvate, tautomer or stereoisomer thereof, wherein: A is selected from R1, R2 and R3 is H, ORa, OCORa, OCOORa, alkyl, alkenyl, alkynyl, etc; R3? is, CORa, COORa, CONRaRb, etc; each of R4to R10 and R12 is alkyl, alkenyl or alkynyl; R11 is H, CORa, COORa, alkyl, alkenyl or alkynyl, or R11 and R12+N+C atoms to which they are attached may form a heterocyclic group; each of R13 and R14 is H, CORa, COORa, alkyl, alkenyl or alkynyl; each Ra and Rb is H, alkyl, alkenyl, alkynyl, etc.
    Type: Application
    Filed: December 16, 2021
    Publication date: June 2, 2022
    Inventors: Carmen CUEVAS MARCHANTE, Juan Manuel DOMINGUEZ CORREA, Andres FRANCESCH SOLLOSO, Maria GARRANZO GARCIA-IBARROLA, Maria Jose MUNOZ ALONSO, Francisco SANCHEZ MADRID, Juan Manuel ZAPATA HERNANDEZ, Alicia GARCIA ARROYO, Maria Angeles URSA PECHARROMAN
  • Patent number: 11339180
    Abstract: A compound of general formula I and pharmaceutical compositions, kits, methods of making, and methods for treating cancer using the same.
    Type: Grant
    Filed: April 2, 2021
    Date of Patent: May 24, 2022
    Assignee: PHARMA MAR, S.A.
    Inventors: María del Carmen Cuevas Marchante, Andrés Francesch Solloso, Valentín Martínez Barrasa
  • Patent number: 11332480
    Abstract: A compound of general formula I, wherein X, R1-R4 take various meanings, for use in the treatment of cancer.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: May 17, 2022
    Assignee: PHARMA MAR, S.A.
    Inventors: María del Carmen Cuevas Marchante, Andrés Francesch Solloso, Valentín Martínez Barrasa
  • Patent number: 11224663
    Abstract: Drug conjugates of formula [D-(X)b-(AA)w-(L)-]n-Ab wherein: D is a drug moiety having the following formula (I) or a pharmaceutically acceptable salt, ester, solvate, tautomer or stereoisomer thereof, wherein: A is selected from (II) and (III) R1, R2 and R3 is H, ORa, OCORa, OCO—ORa, alkyl, alkenyl, alkynyl, etc.; R3? is, CORa, COORa, CONRaRb, etc; each of R4 to R10 and R12 is alkyl, alkenyl or alkynyl; R11 is H, CORa, COORa, alkyl, alkenyl or alkynyl, or R11 and R12+N+C atoms to which they are attached may form a heterocyclic group; each of R13 and R14 is H, CORa, COORa, alkyl, alkenyl or alkynyl; each Ra and Rb is H, alkyl, alkenyl, alkynyl, etc.
    Type: Grant
    Filed: June 2, 2014
    Date of Patent: January 18, 2022
    Assignee: PHARMA MAR, S.A.
    Inventors: Cármen Cuevas Marchante, Juan Manuel Domínguez Correa, Andrés Francesch Solloso, María Garranzo García-Ibarrola, María José Munoz Alonso, Francisco Sánchez Madrid, Juan Manuel Zapata Hernández, Alicia García Arroyo, Maria Ángeles Ursa Pecharromán
  • Publication number: 20210246146
    Abstract: A compound of general formula I and pharmaceutical compositions, kits, methods of making, and methods for treating cancer using the same.
    Type: Application
    Filed: April 2, 2021
    Publication date: August 12, 2021
    Inventors: María del Carmen Cuevas Marchante, Andrés Francesch Solloso, Valentín Martínez Barrasa
  • Publication number: 20210070775
    Abstract: A compound of general formula I, wherein X, R1-R4 take various meanings, for use in the treatment of cancer.
    Type: Application
    Filed: April 27, 2018
    Publication date: March 11, 2021
    Inventors: María del Carmen Cuevas Marchante, Andrés Francesch Solloso, Valentín Martínez Barrasa
  • Patent number: 10538535
    Abstract: A compound of general formula I, wherein X, R1-R4 take various meanings, for use in the treatment of cancer.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: January 21, 2020
    Assignee: PHARMA MAR, S.A.
    Inventors: María del Carmen Cuevas Marchante, Andrés Francesch Solloso, Valentín Martínez Barrasa
  • Patent number: 10442820
    Abstract: A compound of general formula I, wherein X, R1-R4 take various meanings, for use in the treatment of cancer.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: October 15, 2019
    Assignee: PHARMA MAR, S.A.
    Inventors: María del Carmen Cuevas Marchante, Andrés Francesch Solloso, Valentín Martínez Barrasa
  • Publication number: 20180312529
    Abstract: A compound of general formula I, wherein X, R1-R4 take various meanings, for use in the treatment of cancer.
    Type: Application
    Filed: April 27, 2018
    Publication date: November 1, 2018
    Inventors: María del Carmen Cuevas Marchante, Andrés Francesch Solloso, Valentín Martínez Barrasa
  • Patent number: 9428524
    Abstract: This invention relates to compounds of formula II: wherein R1, R2, ProtSH, and ProtNH are as defined, to processes for the synthesis of ecteinascidins of formula I from compounds of formula II, and to processes for the synthesis of compounds of formula II.
    Type: Grant
    Filed: May 24, 2011
    Date of Patent: August 30, 2016
    Assignee: PHARMA MAR, S.A.
    Inventors: Ma Jesús Martin López, Andrés Francesch Solloso, Maria del Carmen Cuevas Marchante
  • Publication number: 20160129128
    Abstract: Drug conjugates of formula [D-(X)b-(AA)w-(L)-]n-Ab wherein: D is a drug moiety having the following formula (I) or a pharmaceutically acceptable salt, ester, solvate, tautomer or stereoisomer thereof, wherein: A is selected from (II) and (III) R1, R2 and R3 is H, ORa, OCORa, OCO—ORa, alkyl, alkenyl, alkynyl, etc; R3? is, CORa, COORa, CONRaRb, etc; each of R4 to R10 and R12 is alkyl, alkenyl or alkynyl; R11 is H, CORa, COORa, alkyl, alkenyl or alkynyl, or R11 and R12+N+C atoms to which they are attached may form a heterocyclic group; each of R13 and R14 is H, CORa, COORa, alkyl, alkenyl or alkynyl; each Ra and Rb is H, alkyl, alkenyl, alkynyl, etc.
    Type: Application
    Filed: June 2, 2014
    Publication date: May 12, 2016
    Inventors: Cármen CUEVAS MARCHANTE, Juan Manuel DOMÍNGUEZ CORREA, Andrés FRANCESCH SOLLOSO, María GARRANZO GARCÍA-IBARROLA, María José MUNOZ ALONSO, Francisco SÁNCHEZ MADRID, Juan Manuel ZAPATA HERNÁNDEZ, Alicia GARCÍA ARROYO, Maria Ángeles URSA PECHARROMÁN
  • Patent number: 8962602
    Abstract: A compound of general formula (I), wherein R1-R17 and the - - - - - - line take various meanings for use in the treatment of cancer.
    Type: Grant
    Filed: April 26, 2011
    Date of Patent: February 24, 2015
    Assignee: Pharma Mar, S.A.
    Inventors: Rogelio Fernández Rodríguez, José Fernando Reyes Benítez, Andrés Francesch Solloso, María del Carmen Cuevas Marchante
  • Patent number: 8501968
    Abstract: Antitumoral compounds obtained from a porifera, of the family Raspailiidae, genus Lithoplocamia, species lithistoides, and derivatives thereof are provided.
    Type: Grant
    Filed: June 29, 2011
    Date of Patent: August 6, 2013
    Assignee: PharmaMar, S.A.
    Inventors: Ma Jesús Martin López, Laura Coello Molinero, José Fernando Reyes Benítez, Alberto Rodríguez Vicente, María Garranzo García-Ibarrola, Carmen Murcia Pérez, Andrés Francesch Solloso, Francisco Sánchez Sancho, Maria del Carmen Cuevas Marchante, Rogelio Fernández Rodríguez
  • Publication number: 20130066067
    Abstract: This invention relates to compounds of formula II: wherein R1, R2, ProtSH, and ProtNH are as defined, to processes for the synthesis of ecteinascidins of formula I from compounds of formula II, and to processes for the synthesis of compounds of formula II.
    Type: Application
    Filed: May 24, 2011
    Publication date: March 14, 2013
    Applicant: Pharma Mar, S.A.
    Inventors: Ma Jesús Martín López, Andrés Francesch Solloso, Maria del Carmen Cuevas Marchante
  • Publication number: 20130040921
    Abstract: A compound of general formula (I), wherein R1-R17 and the ------ line take various meanings for use in the treatment of cancer.
    Type: Application
    Filed: April 26, 2011
    Publication date: February 14, 2013
    Applicant: PHARMA MAR, S.A.
    Inventors: Rogelio Fernández Rodríguez, José Fernando Reyes Benítez, Andrés Francesch Solloso, María del Carmen Cuevas Marchante
  • Patent number: 8324406
    Abstract: Antitumoral compounds obtained from a porifera, of the family Raspailiidae, genus Lithoplocamia, species lithistoides, and derivatives thereof are provided.
    Type: Grant
    Filed: June 15, 2007
    Date of Patent: December 4, 2012
    Assignee: Pharma Mar, S.A.
    Inventors: Ma Jesús Martín López, Laura Coello Molinero, José Fernando Reyes Benítez, Alberto Rodríguez Vicente, María Garranzo García-Ibarrola, Carmen Murcia Pérez, Andrés Francesch Solloso, Francisco Sánchez Sancho, María del Carmen Cuevas Marchante, Rogelio Fernández Rodríguez
  • Publication number: 20120190870
    Abstract: Antitumoral compounds obtained from a porifera, of the family Raspailiidae, genus Lithoplocamia, species lithistoides, and derivatives thereof are provided.
    Type: Application
    Filed: June 29, 2011
    Publication date: July 26, 2012
    Inventors: Ma Jesús Martín López, Laura Coello Molinero, José Fernando Reyes Benítez, Alberto Rodríguez Vicente, María Garranzo García- Ibarrola, Carmen Murcia Pérez, Andrés Francesch Solloso, Francisco Sánchez Sancho, María del Carmen Cuevas Marchante, Rogelio Fernández Rodríguez