Abstract: Patient imaging systems, such as PET imaging systems, for example, may suffer from the introduction of artificially introduced noise. This noise is, typically, introduced during iterations of reconstruction algorithms, such as the least-squares algorithms, which attempts to recreate a 2D or a 3D image from raw acquisition information. The noise appears as “hot-spots” in the reconstructed image. Approaches to address these artefacts use filtering approaches. Typically, a least-squares reconstruction is supplemented with a penalty term, an approach known as “Relative Difference Penalty”. The penalty parameter causes the reconstruction algorithm to filter more or less strongly at certain regions of the reconstruction. The present application proposes an approach which supplements the penalty term with continuous probability information about the likelihood of an edge being present in a portion of an image.

Abstract: An imaging system includes a magnetic resonance portion that produces an electric field and a second imaging portion, including a detector with a two dimensional array of detector tiles, wherein adjacent tiles along an axial direction are spaced apart by an electrically conductive material, which shields the tiles from the electric field. An imaging system includes a first imaging portion having a detector, which includes an array of scintillation crystals and a photo-sensor coupled to the array of scintillation crystals, wherein an output of the photo-sensor includes a unique ratio of information that identifies each crystal.

Abstract: An imaging system includes a magnetic resonance portion that produces an electric field and a second imaging portion, including a detector with a two dimensional array of detector tiles, wherein adjacent tiles along an axial direction are spaced apart by an electrically conductive material, which shields the tiles from the electric field. An imaging system includes a first imaging portion having a detector, which includes an array of scintillation crystals and a photo-sensor coupled to the array of scintillation crystals, wherein an output of the photo-sensor includes a unique ratio of information that identifies each crystal.

Abstract: A magnetic resonance (MR) image segmentation processor (32) is configured to identify one or more geometrical regions of a subject using an MR image of the subject. An emission data reconstruction processor (40) is configured to generate an attenuation map (54) of the subject by assigning initial attenuation values (52) to the geometrical regions of the subject, and to: (i) process (56) emission data acquired from the subject to generate an emission image (58) of the subject, the processing employing the attenuation map of the subject; (ii) update (60) the attenuation map based on corrections calculated using the emission image of the subject; and (iii) iterate operations (i) and (ii) to iteratively generate a reconstructed emission image of the subject.

Abstract: A foundation, particularly a foundation of a wind turbine, is provided. The foundation includes a central foundation member and a plurality of foundation segments which are segments of a circular, ring shaped or polygonal foundation element and which are connected to the central foundation member using a plurality of locking elements.

Abstract: A magnetic resonance (MR) image segmentation processor (32) is configured to identify one or more geometrical regions of a subject using an MR image of the subject. An emission data reconstruction processor (40) is configured to generate an attenuation map (54) of the subject by assigning initial attenuation values (52) to the geometrical regions of the subject, and to: (i) process (56) emission data acquired from the subject to generate an emission image (58) of the subject, the processing employing the attenuation map of the subject; (ii) update (60) the attenuation map based on corrections calculated using the emission image of the subject; and (iii) iterate operations (i) and (ii) to iteratively generate a reconstructed emission image of the subject.

Abstract: Provided is a method comprising introducing a sample comprising a plurality of oligonucleotides into an ion pair high performance liquid chromatography column having a buffered mobile phase and allowing at least a portion of the oligonucleotides to separate; allowing the oligonucleotides to elute from the column; and introducing the oligonucleotides into a mass spectrometer and quantifying at least a portion of the oligonucleotides by mass spectrometry. In the method, at least a portion of the oligonucleotides are co-eluting oligonucleotides that differ in mass by no more than 20%; and the buffered mobile phase causes at least 50 mole percent of co-eluting oligonucleotides to have the same charge when they enter the mass spectrometer.

Abstract: A foundation, particularly a foundation of a wind turbine, is provided. The foundation includes a central foundation member and a plurality of foundation segments which are segments of a circular, ring shaped or polygonal foundation element and which are connected to the central foundation member using a plurality of locking elements.

Abstract: Provided is a method comprising introducing a sample comprising a plurality of oligonucleotides into an ion pair high performance liquid chromatography column having a buffered mobile phase and allowing at least a portion of the oligonucleotides to separate; allowing the oligonucleotides to elute from the column; and introducing the oligonucleotides into a mass spectrometer and quantifying at least a portion of the oligonucleotides by mass spectrometry. In the method, at least a portion of the oligonucleotides are co-eluting oligonucleotides that differ in mass by no more than 20%; and the buffered mobile phase causes at least 50 mole percent of co-eluting oligonucleotides to have the same charge when they enter the mass spectrometer.

Abstract: The present invention relates to oligonucleotide synthesis. In particular, the present invention provides methods for characterizing samples useful for making oligonucleotides.

Abstract: The invention relates to a system for the data transmission of digital transmission data (17, 18) between a first digital protective device (1) and a second digital protective device (9) on a section (A) of an energy supply line (2) in a transmission direction (15) and in a reception direction (16). The first digital protective device (1) is connected to an end (6) of an electrical data transmission line (7) via a first coupling device (5). The second digital protective device (9) is connected to the other end (12) of the electrical data transmission line (7) via a second coupling device (11). In order to establish data transmission with little complication, the data transmission line (7) is one-paired, and both coupling devices (5, 11) are adapted to enable transmission of digital transmission data in the transmission and reception direction (15 or 16) on the one-paired data transmission line (7) in the manner of a digital telecommunication transmission.

Abstract: The invention relates to a system for the data transmission of digital transmission data (17, 18) between a first digital protective device (1) and a second digital protective device (9) on a section (A) of an energy supply line (2) in a transmission direction (15) and in a reception direction (16). The first digital protective device (1) is connected to an end (6) of an electrical data transmission line (7) via a first coupling device (5). The second digital protective device (9) is connected to the other end (12) of the electrical data transmission line (7) via a second coupling device (11). In order to establish data transmission with little complication, the data transmission line (7) is one-paired, and both coupling devices (5, 11) are adapted to enable transmission of digital transmission data in the transmission and reception direction (15 or 16) on the one-paired data transmission line (7) in the manner of a digital telecommunication transmission.