Patents by Inventor Andre Koltermann
Andre Koltermann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10202421Abstract: The invention relates to a novel compounds targeting human cancer cells, a method for synthesis of such compounds, and use of such compounds in treating cancer.Type: GrantFiled: September 2, 2016Date of Patent: February 12, 2019Inventor: Andre Koltermann
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Patent number: 9637434Abstract: The invention relates to a method for obtaining ethanol from a carbohydrate-containing raw substrate wherein the ethanol that is produced is separated during fermentation using a carrier gas. The invention further relates to the adsorption of the ethanol from the gas phase to an adsorber, the desorption of the ethanol during a subsequent process step, and to the further concentration of the ethanol.Type: GrantFiled: December 8, 2010Date of Patent: May 2, 2017Assignee: SUD-CHEMIE IP GMBH & CO. KGInventors: Michael Zavrel, Michael Kraus, Sandra Hofmann, Ulrich Kettling, Andre Koltermann, Christian Ott, Zdravko Dragovic
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Publication number: 20170096452Abstract: The invention relates to a novel compounds targeting human cancer cells, a method for synthesis of such compounds, and use of such compounds in treating cancer.Type: ApplicationFiled: September 2, 2016Publication date: April 6, 2017Inventor: Andre Koltermann
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Patent number: 9458443Abstract: The invention discloses cellulase enzymes with optimized properties for processing of cellulose- and lignocellulose-containing substrates. In particular, cellobiohydrolase enzymes with preferred characteristics are disclosed. The present invention provides fusion, insertion, deletion and/or substitution variants of such enzymes. Enzyme variants have enhanced thermostability, proteolytic stability, specific activity and/or stability at extreme pH. Nucleic acid molecules encoding said enzymes, a composition comprising said enzymes, a method for preparation, and the use for cellulose processing and/or for the production of biofuels are disclosed.Type: GrantFiled: February 11, 2011Date of Patent: October 4, 2016Assignee: SUD-CHEMIE IP GMBH & CO. KGInventors: Ulrich Kettling, Christoph Reisinger, Thomas Brück, Andre Koltermann, Jochen Gerlach, Isabel Unterstrasser, Lutz Röcher, Markus Rarbach, Jörg Claren, Andreas Kohl, Jan Carsten Pieck, Dominik Schlosser
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Patent number: 9273295Abstract: The present invention relates to enzymes and processes. In particular, there is described an isolated polypeptide comprising the amino acid sequence corresponding to Citrobacter freundii phytase or a homologue, a modified form, a functional equivalent or an effective fragment thereof. There is also described a host cell transformed or transfected with a nucleic acid encoding a bacterial phytase enzyme or a modified form as well as the use of such a phytase or modified form in food or animal feed.Type: GrantFiled: September 14, 2011Date of Patent: March 1, 2016Assignee: DUPONT NUTRITION BIOSCIENCES APSInventors: Andrei Miasnikov, Vijay Kumar, Oliver Kensch, Klaus Pellangahr, Birgitta Leuthner, Ulrich Kettling, Andre Koltermann
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Publication number: 20150218594Abstract: Provided are enzymatic processes for the production of chemicals like ethanol from carbon sources like glucose, in particular, a process for the production of a target chemical is disclosed using a cell-free enzyme system that converts carbohydrate sources to the intermediate pyruvate and subsequently the intermediate pyruvate to the target chemical wherein a minimized number of enzymes and only one cofactor is employed.Type: ApplicationFiled: August 20, 2013Publication date: August 6, 2015Applicant: CLARIANT PRODUKTE (DEUTSCHLAND) GMBHInventors: Michael Kraus, André Koltermann, Ulrich Kettling, Daniel Garbe, Thomas Brueck, Jan-Karl Guterl, Volker Sieber
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Patent number: 9005936Abstract: The invention is directed to a liquefied sugar beet and/or sugar cane biomass material as well as production methods and uses thereof. The liquefied biomass is storage stable and can be used for the production of a product resulting from fermentation.Type: GrantFiled: May 21, 2010Date of Patent: April 14, 2015Assignee: Süd-Chemie IP GmbH & Co. KGInventors: Andre Koltermann, Markus Rarbach, Thomas Bruck, Jochen Gerlach, Isabel Unterstrasser, Andreas Kohl, Zdravko Dragovic, Ulrich Kettling
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Patent number: 8859247Abstract: An enzymatic process is described for the production of chemicals from carbon sources. In particular, according to one aspect, a process for the production of a target organic compound from a carbon source by a cell-free enzyme system is disclosed.Type: GrantFiled: December 28, 2009Date of Patent: October 14, 2014Assignee: Süd-Chemie IP GmbH & Co. KGInventors: Andre Koltermann, Ulrich Kettling, Volker Sieber
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Patent number: 8679795Abstract: The present invention relates to polypeptides having xylanase activity and nucleic acid sequences encoding such polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides. One specific application of the xylanase is the selective hydrolysis of pentose sugar components of hemicellulose-containing plant biomass. The nucleotide sequence may be used for the production of the xylanase or optimized mutants thereof.Type: GrantFiled: December 15, 2010Date of Patent: March 25, 2014Assignee: Sud-Chemie IP GmbH & Co. KGInventors: Andreas Kohl, Isabel Unterstrasser, Markus Rarbach, Andre Koltermann, Christoph Reisinger, Thomas Brück, Ulrich Kettling, Gudmundur O. Hreggvidsson, Olafur H. Fridjonsson
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Patent number: 8524471Abstract: The invention concerns a method for the enzymatic treatment of raw polymeric feedstock comprising the following steps: (a) preferably separation of soluble components from the raw polymeric feedstock, (b) treating the raw polymeric feedstock with an enzyme system in order to liberate defined soluble monomeric or oligomeric building blocks from the insoluble raw polymeric feedstock; and (c) separating the defined monomeric or oligomeric building blocks produced in step b) from the remainder of the raw polymeric feedstock. Preferably, the enzyme system used in step b) contains not more than 50%, preferably not more than 20%, more preferably not more than 10%, more preferably not more than 5%, more preferably not more than 2%, more preferably not more than 1% of other enzyme activities apart from the enzyme activity resulting in liberation of said defined monomeric or oligomeric building blocks from the raw polymeric feedstock according to step b).Type: GrantFiled: June 12, 2008Date of Patent: September 3, 2013Assignee: Sud-Chemie IP GmbH & Co. KGInventors: Andre Koltermann, Ulrich Kettling, Thomas Bruck, Markus Rarbach
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Patent number: 8470963Abstract: The invention relates to a synthetic bifunctional non-antibody compound comprising one or more effector moieties and one or more binder moieties, wherein the effector moieties are operably linked to the binder moieties via a linker, the effector moieties are ligands to at least one pathogen pattern recognition receptor (PRR) and the binder moieties bind to a marker of a tumor cell.Type: GrantFiled: July 2, 2007Date of Patent: June 25, 2013Assignee: Sku Asset Management GmbHInventor: Andre Koltermann
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Publication number: 20130136825Abstract: The present invention relates to enzymes and processes. In particular, there is described an isolated polypeptide comprising the amino acid sequence corresponding to Citrobacter freundii phytase or a homologue, a modified form, a functional equivalent or an effective fragment thereof. There is also described a host cell transformed or transfected with a nucleic acid encoding a bacterial phytase enzyme or a modified form as well as the use of such a phytase or modified form in food or animal feed.Type: ApplicationFiled: September 14, 2011Publication date: May 30, 2013Applicant: DUPONT NUTRITION BIOSCIENCES APSInventors: Andrei Miasnikov, Vijay Kumar, Oliver Kensch, Klaus Pellangahr, Birgitta Leuthner, Ulrich Kettling, Andre Koltermann
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Publication number: 20130123115Abstract: The invention discloses cellulase enzymes with optimized properties for processing of cellulose- and lignocellulose-containing substrates. In particular, cellobiohydrolase enzymes with preferred characteristics are disclosed. The present invention provides fusion, insertion, deletion and/or substitution variants of such enzymes. Enzyme variants have enhanced thermostability, proteolytic stability, specific activity and/or stability at extreme pH. Nucleic acid molecules encoding said enzymes, a composition comprising said enzymes, a method for preparation, and the use for cellulose processing and/or for the production of biofuels are disclosed.Type: ApplicationFiled: February 11, 2011Publication date: May 16, 2013Applicant: SUD-CHEMIE IP GMBH & CO. KGInventors: Ulrich Kettling, Christoph Reisinger, Thomas Brück, Andre Koltermann, Jochen Gerlach, Isabel Unterstrasser, Lutz Röcher, Markus Rarbach, Jörg Claren, Andreas Kohl, Jan Carsten Pieck, Dominik Schlosser
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Publication number: 20130109062Abstract: The present invention relates to polypeptides having xylanase activity and nucleic acid sequences encoding such polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides. One specific application of the xylanase is the selective hydrolysis of pentose sugar components of hemicellulose-containing plant biomass. The nucleotide sequence may be used for the production of the xylanase or optimized mutants thereof.Type: ApplicationFiled: December 15, 2010Publication date: May 2, 2013Applicant: SÜD-CHEMIE AGInventors: Andreas Kohl, Isabel Unterstrasser, Markus Rarbach, Andre Koltermann, Christoph Reisinger, Thomas Brück, Ulrich Kettling, Gudmundur O. Hreggvidsson, Olafur H. Fridjonsson
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Publication number: 20130095543Abstract: The invention relates to a method for obtaining ethanol from a carbohydrate-containing raw substrate wherein the ethanol that is produced is separated during fermentation using a carrier gas. The invention further relates to the adsorption of the ethanol from the gas phase to an adsorber, the desorption of the ethanol during a subsequent process step, and to the further concentration of the ethanol.Type: ApplicationFiled: December 8, 2010Publication date: April 18, 2013Applicant: SUD-CHEMIE AGInventors: Michael Zavrel, Michael Kraus, Sandra Hofmann, Ulrich Kettling, Andre Koltermann, Christian Ott, Zdravko Dragovic
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Publication number: 20120301578Abstract: The present invention relates to enzymes and processes. In particular, there is described an isolated polypeptide comprising the amino acid sequence corresponding to Citrobacter freundii phytase or a homologue, a modified form, a functional equivalent or an effective fragment thereof. There is also described a host cell transformed or transfected with a nucleic acid encoding a bacterial phytase enzyme or a modified form as well as the use of such a phytase or modified form in food or animal feed.Type: ApplicationFiled: September 14, 2011Publication date: November 29, 2012Inventors: Andrei Miasnikov, Vijay Kumar, Oliver Kensch, Klaus Pellangahr, Birgitta Leuthner, Ulrich Kettling, Andre Koltermann
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Publication number: 20120135475Abstract: The invention is directed to a liquefied sugar beet and/or sugar cane biomass material as well as production methods and uses thereof. The liquefied biomass is storage stable and can be used for the production of a product resulting from fermentation.Type: ApplicationFiled: May 21, 2010Publication date: May 31, 2012Applicant: SUD-CHEMIE AGInventors: Andre Koltermann, Markus Rarbach, Thomas Bruck, Jochen Gerlach, Isabel Unterstrasser, Andreas Kohl, Zdravko Dragovic, Ulrich Kettling
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Patent number: 8143045Abstract: The present invention relates to enzymes and processes. In particular, there is described an isolated polypeptide comprising the amino acid sequence corresponding to Citrobacter freundii phytase or a homologue, a modified form, a functional equivalent or an effective fragment thereof. There is also described a host cell transformed or transfected with a nucleic acid encoding a bacterial phytase enzyme or a modified form as well as the use of such a phytase or modified form in food or animal feed.Type: GrantFiled: April 3, 2007Date of Patent: March 27, 2012Assignee: Danisco A/SInventors: Andrei Miasnikov, Vijay Kumar, Oliver Kensch, Klaus Pellangahr, Birgitta Leuthner, Ulrich Kettling, Andre Koltermann
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Publication number: 20120064194Abstract: The present invention relates to enzymes and processes. In particular, there is described a host 3140 cell transformed or transfected with a nucleic acid encoding a bacterial phytase enzyme and variants thereof.Type: ApplicationFiled: July 27, 2011Publication date: March 15, 2012Inventors: Andrei Miasnikov, Vijay Kumar, Oliver Kensch, Klaus Pellengahr, Birgitta Leuthner, Ulrich Kettling, Andre Koltermann
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Publication number: 20120010153Abstract: The invention relates to a novel compounds targeting human cancer cells, a method for synthesis of such compounds, and use of such compounds in treating cancer.Type: ApplicationFiled: January 14, 2010Publication date: January 12, 2012Inventor: Andre Koltermann